ATE348619T1 - Ivabradin enthaltende pharmazeutische zusammensetzung mit oraler dispersion - Google Patents
Ivabradin enthaltende pharmazeutische zusammensetzung mit oraler dispersionInfo
- Publication number
- ATE348619T1 ATE348619T1 AT03731734T AT03731734T ATE348619T1 AT E348619 T1 ATE348619 T1 AT E348619T1 AT 03731734 T AT03731734 T AT 03731734T AT 03731734 T AT03731734 T AT 03731734T AT E348619 T1 ATE348619 T1 AT E348619T1
- Authority
- AT
- Austria
- Prior art keywords
- pharmaceutical composition
- composition containing
- oral dispersion
- containing ivabradine
- ivabradine
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0200791A FR2834896B1 (fr) | 2002-01-23 | 2002-01-23 | Composition pharmaceutique orodispersible d'ivabradine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE348619T1 true ATE348619T1 (de) | 2007-01-15 |
Family
ID=27589555
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03731734T ATE348619T1 (de) | 2002-01-23 | 2003-01-22 | Ivabradin enthaltende pharmazeutische zusammensetzung mit oraler dispersion |
Country Status (28)
| Country | Link |
|---|---|
| US (2) | US20050106238A1 (de) |
| EP (1) | EP1474152B1 (de) |
| JP (1) | JP4500052B2 (de) |
| KR (1) | KR100613550B1 (de) |
| CN (1) | CN1278688C (de) |
| AR (1) | AR038206A1 (de) |
| AT (1) | ATE348619T1 (de) |
| AU (1) | AU2003215706B2 (de) |
| BR (1) | BRPI0307056B1 (de) |
| CA (1) | CA2473203C (de) |
| CY (1) | CY1108854T1 (de) |
| DE (1) | DE60310526T2 (de) |
| DK (1) | DK1474152T3 (de) |
| EA (1) | EA007681B1 (de) |
| ES (1) | ES2278165T3 (de) |
| FR (1) | FR2834896B1 (de) |
| GE (1) | GEP20063820B (de) |
| HK (1) | HK1076741A1 (de) |
| MA (1) | MA27102A1 (de) |
| MX (1) | MXPA04007199A (de) |
| NO (1) | NO333698B1 (de) |
| NZ (1) | NZ533842A (de) |
| PL (1) | PL204938B1 (de) |
| PT (1) | PT1474152E (de) |
| SI (1) | SI1474152T1 (de) |
| UA (1) | UA78278C2 (de) |
| WO (1) | WO2003061662A1 (de) |
| ZA (1) | ZA200405129B (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2868777B1 (fr) * | 2004-04-13 | 2006-05-26 | Servier Lab | Nouveau procede de synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable |
| FR2882553B1 (fr) * | 2005-02-28 | 2007-05-04 | Servier Lab | Forme cristalline beta du chlorhydrate de l'ivabradine, son procede de preparation, et les compositions pharmaceutiques qui la contiennent |
| EP1917979A4 (de) * | 2005-08-23 | 2009-06-03 | Astellas Pharma Inc | Therapeutikum für vorhofflimmern |
| FR2894825B1 (fr) * | 2005-12-21 | 2010-12-03 | Servier Lab | Nouvelle association d'un inhibiteur du courant if sinusal et d'un inhibiteur de l'enzyme de conversion et les compositions pharmaceutiques qui la contiennent |
| FR2911279B1 (fr) * | 2007-01-11 | 2009-03-06 | Servier Lab | Utilisation de l'ivabradine pour l'obtention de medicaments destines au traitement de la dysfonction endotheliale |
| WO2010128525A2 (en) | 2009-05-04 | 2010-11-11 | Dinesh Shantilal Patel | A formulation of ivabradine for treating the cardiovascular disease |
| CA2800444C (en) | 2010-06-14 | 2018-03-20 | Ratiopharm Gmbh | Ivabradine-containing pharmaceutical composition |
| CN103393611B (zh) * | 2013-08-06 | 2015-08-19 | 南京正大天晴制药有限公司 | 一种盐酸伊伐布雷定片剂及其制备方法 |
| WO2016102423A1 (en) * | 2014-12-22 | 2016-06-30 | Ratiopharm Gmbh | Composition comprising ivabradine in a dissolved form |
| GR1008821B (el) | 2015-06-11 | 2016-08-01 | Φαρματεν Ανωνυμος Βιομηχανικη Και Εμπορικη Εταιρεια Φαρμακευτικων Ιατρικων Και Καλλυντικων Προϊοντων | Φαρμακευτικο σκευασμα που περιλαμβανει υδροχλωρικη ιβαμπραδινη και μεθοδος παρασκευης αυτου |
| CN106265582A (zh) * | 2016-08-31 | 2017-01-04 | 辰欣药业股份有限公司 | 一种盐酸伊伐布雷定片及其制备工艺 |
| CA3145456A1 (en) * | 2019-07-01 | 2021-01-07 | Orion Corporation | Methods for administering (r)-n-[4-(1,4,5,6-tetrahydro-6-oxo-3-pyridazinyl)phenyl]acetamide |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT376147B (de) * | 1980-12-15 | 1984-10-10 | Gergely Gerhard | Verfahren und vorrichtung zum granulieren eines pulvergemisches |
| DE3505433A1 (de) * | 1985-02-16 | 1986-08-21 | Basf Ag, 6700 Ludwigshafen | Direkttablettierhilfsmittel |
| DE3506276C1 (de) * | 1985-02-22 | 1986-04-24 | Meggle Milchindustrie Gmbh & Co Kg, 8094 Reitmehring | Direkttablettiermittel |
| JP3253127B2 (ja) * | 1991-06-07 | 2002-02-04 | 帝國製薬株式会社 | 生理活性ポリペプチド含有製剤 |
| FR2681862B1 (fr) * | 1991-09-27 | 1993-11-12 | Adir Cie | Nouvelles (benzocycloalkyl)alkylamines, leur procede de preparation, et les compositions pharmaceutiques qui les contiennent. |
| FR2710265B1 (fr) * | 1993-09-22 | 1995-10-20 | Adir | Composition pharmaceutique bioadhésive pour la libération contrôlée de principes actifs. |
| EP0745382B1 (de) * | 1994-01-31 | 2003-11-12 | Yamanouchi Pharmaceutical Co. Ltd. | Intraoral löslicher formpressling und verfahren zu seiner herstellung |
| WO1998051328A1 (en) * | 1997-05-09 | 1998-11-19 | Feronpatent Limited | Stabilisation of interferons in aqueous solution for manufacture of sublingually administered tablets |
| US6024981A (en) * | 1997-04-16 | 2000-02-15 | Cima Labs Inc. | Rapidly dissolving robust dosage form |
| ES2178876T5 (es) * | 1998-03-06 | 2012-10-01 | Aptalis Pharma S.R.L. | Pastilla de desintegración rápida |
| JP2983973B1 (ja) * | 1998-10-13 | 1999-11-29 | 大正薬品工業株式会社 | 口腔内速崩壊性固形製剤 |
| JP2000273039A (ja) * | 1999-01-20 | 2000-10-03 | Taisho Pharmaceut Co Ltd | 口腔内崩壊性組成物 |
| JP2001058944A (ja) * | 1999-06-18 | 2001-03-06 | Takeda Chem Ind Ltd | 速崩壊性固形製剤 |
| ATE371439T1 (de) * | 2000-07-27 | 2007-09-15 | Roquette Freres | Granulat bestehend aus stärke und laktose |
| UA80393C2 (uk) * | 2000-12-07 | 2007-09-25 | Алтана Фарма Аг | Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці |
| FR2818552B1 (fr) * | 2000-12-26 | 2003-02-07 | Servier Lab | Compositions pharmaceutique solide thermoformable pour la liberation controlee d'ivabradine |
| FR2834889B1 (fr) * | 2002-01-18 | 2004-04-02 | Roquette Freres | Forme pharmaceutique solide orodispersible |
-
2002
- 2002-01-23 FR FR0200791A patent/FR2834896B1/fr not_active Expired - Fee Related
-
2003
- 2003-01-22 AT AT03731734T patent/ATE348619T1/de active
- 2003-01-22 DK DK03731734T patent/DK1474152T3/da active
- 2003-01-22 UA UA20040806963A patent/UA78278C2/uk unknown
- 2003-01-22 EA EA200400927A patent/EA007681B1/ru not_active IP Right Cessation
- 2003-01-22 PL PL370161A patent/PL204938B1/pl unknown
- 2003-01-22 EP EP03731734A patent/EP1474152B1/de not_active Expired - Lifetime
- 2003-01-22 GE GE5627A patent/GEP20063820B/en unknown
- 2003-01-22 AU AU2003215706A patent/AU2003215706B2/en not_active Ceased
- 2003-01-22 MX MXPA04007199A patent/MXPA04007199A/es active IP Right Grant
- 2003-01-22 SI SI200330632T patent/SI1474152T1/sl unknown
- 2003-01-22 CA CA2473203A patent/CA2473203C/fr not_active Expired - Fee Related
- 2003-01-22 BR BRPI0307056-5A patent/BRPI0307056B1/pt not_active IP Right Cessation
- 2003-01-22 DE DE60310526T patent/DE60310526T2/de not_active Expired - Lifetime
- 2003-01-22 US US10/502,594 patent/US20050106238A1/en not_active Abandoned
- 2003-01-22 NZ NZ533842A patent/NZ533842A/en not_active IP Right Cessation
- 2003-01-22 ES ES03731734T patent/ES2278165T3/es not_active Expired - Lifetime
- 2003-01-22 CN CNB038027119A patent/CN1278688C/zh not_active Expired - Fee Related
- 2003-01-22 JP JP2003561606A patent/JP4500052B2/ja not_active Expired - Fee Related
- 2003-01-22 WO PCT/FR2003/000198 patent/WO2003061662A1/fr active IP Right Grant
- 2003-01-22 PT PT03731734T patent/PT1474152E/pt unknown
- 2003-01-22 KR KR1020047011350A patent/KR100613550B1/ko not_active IP Right Cessation
- 2003-01-22 AR ARP030100177A patent/AR038206A1/es unknown
-
2004
- 2004-06-28 ZA ZA2004/05129A patent/ZA200405129B/en unknown
- 2004-07-12 MA MA27776A patent/MA27102A1/fr unknown
- 2004-08-18 NO NO20043440A patent/NO333698B1/no not_active IP Right Cessation
-
2005
- 2005-10-10 HK HK05108934A patent/HK1076741A1/xx not_active IP Right Cessation
-
2007
- 2007-01-16 CY CY20071100061T patent/CY1108854T1/el unknown
-
2010
- 2010-06-23 US US12/803,280 patent/US20100267693A1/en not_active Abandoned
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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