ATE340869T1 - Massenmarkierte hybridisierungssonden - Google Patents

Massenmarkierte hybridisierungssonden

Info

Publication number
ATE340869T1
ATE340869T1 AT98900611T AT98900611T ATE340869T1 AT E340869 T1 ATE340869 T1 AT E340869T1 AT 98900611 T AT98900611 T AT 98900611T AT 98900611 T AT98900611 T AT 98900611T AT E340869 T1 ATE340869 T1 AT E340869T1
Authority
AT
Austria
Prior art keywords
hybridization probe
mass
base sequence
mass marked
marked hybridization
Prior art date
Application number
AT98900611T
Other languages
English (en)
Inventor
Guenter Schmidt
Andrew Hugin Thompson
Robert Alexander Wal Johnstone
Original Assignee
Xzillion Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9700746.2A external-priority patent/GB9700746D0/en
Priority claimed from GBGB9718255.4A external-priority patent/GB9718255D0/en
Priority claimed from GBGB9726953.4A external-priority patent/GB9726953D0/en
Application filed by Xzillion Gmbh & Co Kg filed Critical Xzillion Gmbh & Co Kg
Application granted granted Critical
Publication of ATE340869T1 publication Critical patent/ATE340869T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6872—Methods for sequencing involving mass spectrometry
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Discharge Heating (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Surgical Instruments (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT98900611T 1997-01-15 1998-01-15 Massenmarkierte hybridisierungssonden ATE340869T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9700746.2A GB9700746D0 (en) 1996-10-04 1997-01-15 Hybridisation probes
GBGB9718255.4A GB9718255D0 (en) 1996-10-04 1997-08-28 Hybridisation probes
GBGB9726953.4A GB9726953D0 (en) 1997-12-19 1997-12-19 Hybridisation probes

Publications (1)

Publication Number Publication Date
ATE340869T1 true ATE340869T1 (de) 2006-10-15

Family

ID=27268674

Family Applications (2)

Application Number Title Priority Date Filing Date
AT98900611T ATE340869T1 (de) 1997-01-15 1998-01-15 Massenmarkierte hybridisierungssonden
AT03076965T ATE374836T1 (de) 1997-01-15 1998-01-15 Massenmarkierte hybridisierungssonden

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT03076965T ATE374836T1 (de) 1997-01-15 1998-01-15 Massenmarkierte hybridisierungssonden

Country Status (10)

Country Link
EP (2) EP0979305B1 (de)
JP (3) JP3884087B2 (de)
CN (1) CN100434531C (de)
AT (2) ATE340869T1 (de)
AU (1) AU725966B2 (de)
CA (2) CA2441655A1 (de)
DE (2) DE69838519T2 (de)
IL (1) IL130885A (de)
NZ (1) NZ336769A (de)
WO (1) WO1998031830A1 (de)

Families Citing this family (94)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9707980D0 (en) 1997-04-21 1997-06-11 Brax Genomics Ltd Characterising DNA
US6312904B1 (en) * 1997-07-11 2001-11-06 Xzillion Gmbh & Co. Kg Characterizing nucleic acid
AU738237B2 (en) * 1997-07-22 2001-09-13 Qiagen Genomics, Inc. Methods and compositions for analyzing nucleic acid molecules utilizing sizing techniques
GB9718921D0 (en) * 1997-09-05 1997-11-12 Brax Genomics Ltd Catalytically generated mass labels
JP2001516591A (ja) * 1997-09-15 2001-10-02 ブラックス グループ リミテッド 質量分析法による核酸の分析方法
WO1999029898A2 (de) * 1997-12-05 1999-06-17 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Verfahren zur identifikation von nucleinsäuren durch matrix-assistierte laser desorptions/ionisations massenspektrometrie
GB9815163D0 (en) * 1998-07-13 1998-09-09 Brax Genomics Ltd Compounds
GB9815166D0 (en) * 1998-07-13 1998-09-09 Brax Genomics Ltd Compounds for mass spectrometry
GB9815164D0 (en) * 1998-07-13 1998-09-09 Brax Genomics Ltd Compounds for mass spectrometry
GB9823646D0 (en) 1997-12-19 1998-12-23 Brax Genomics Ltd Compounds for mass spectrometry
WO1999060007A2 (en) * 1998-05-15 1999-11-25 Isis Innovation Limited Libraries of oligomers labelled with different tags
US7399844B2 (en) 1998-07-09 2008-07-15 Agilent Technologies, Inc. Method and reagents for analyzing the nucleotide sequence of nucleic acids
US6270976B1 (en) 1998-09-15 2001-08-07 Brax Group Limited Characterizing nucleic acid by mass spectrometry
JP3668075B2 (ja) * 1999-10-12 2005-07-06 光夫 板倉 遺伝物質シーケンス決定用懸濁系、その懸濁系を用いた遺伝物質シーケンス決定方法およびその懸濁系を用いたＳＮＰｓ高速スコアリング方法
US6509157B1 (en) * 1999-11-05 2003-01-21 Roche Molecular Systems, Inc 3 blocked nucleic acid amplification primers
DE19963536C2 (de) * 1999-12-20 2003-04-10 Epigenomics Ag Verfahren zur Analyse von Nukleinsäuresequenzen
JP2001204463A (ja) * 2000-01-27 2001-07-31 Toyo Kohan Co Ltd ヌクレオチド固定用担体
GB0006141D0 (en) 2000-03-14 2000-05-03 Brax Group Ltd Mass labels
CA2408291C (en) 2000-05-04 2014-07-15 Yale University High density protein arrays for screening of protein activity
AU8356201A (en) * 2000-08-11 2002-02-25 Agilix Corp Ultra-sensitive detection systems
US20040209251A1 (en) 2000-10-19 2004-10-21 Schneider Luke V Methods for determining protein and peptide terminal sequences
WO2002050307A1 (en) * 2000-12-12 2002-06-27 Chugai Seiyaku Kabushiki Kaisha Method of detecting polymorphism in dna by using mass spectroscopy
US7666588B2 (en) 2001-03-02 2010-02-23 Ibis Biosciences, Inc. Methods for rapid forensic analysis of mitochondrial DNA and characterization of mitochondrial DNA heteroplasmy
US7226739B2 (en) 2001-03-02 2007-06-05 Isis Pharmaceuticals, Inc Methods for rapid detection and identification of bioagents in epidemiological and forensic investigations
US20030027135A1 (en) 2001-03-02 2003-02-06 Ecker David J. Method for rapid detection and identification of bioagents
WO2004060278A2 (en) 2002-12-06 2004-07-22 Isis Pharmaceuticals, Inc. Methods for rapid identification of pathogens in humans and animals
US20040121309A1 (en) 2002-12-06 2004-06-24 Ecker David J. Methods for rapid detection and identification of bioagents in blood, bodily fluids, and bodily tissues
US7217510B2 (en) 2001-06-26 2007-05-15 Isis Pharmaceuticals, Inc. Methods for providing bacterial bioagent characterizing information
PT1425586E (pt) 2001-09-14 2007-12-31 Electrophoretics Ltd Marcadores de massa
JP4606028B2 (ja) * 2002-04-04 2011-01-05 エレクトロフォレティクス リミテッド 被分析物の分析方法
JP2004037128A (ja) * 2002-06-28 2004-02-05 Canon Inc マトリクス援助レーザー脱着／イオン化飛行時間型質量分析法による基板上の物質の解析方法
SG190453A1 (en) 2002-10-29 2013-06-28 Target Discovery Inc Method for increasing ionization efficiency in mass spectroscopy
EP1588145B1 (de) 2003-01-30 2011-07-06 Life Technologies Corporation Verfahren, mixturen, kits und zusammensetzungen bezüglich der analytbestimmung
US8158354B2 (en) 2003-05-13 2012-04-17 Ibis Biosciences, Inc. Methods for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture
US7964343B2 (en) 2003-05-13 2011-06-21 Ibis Biosciences, Inc. Method for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture
US8288523B2 (en) 2003-09-11 2012-10-16 Ibis Biosciences, Inc. Compositions for use in identification of bacteria
US8546082B2 (en) 2003-09-11 2013-10-01 Ibis Biosciences, Inc. Methods for identification of sepsis-causing bacteria
US8097416B2 (en) 2003-09-11 2012-01-17 Ibis Biosciences, Inc. Methods for identification of sepsis-causing bacteria
JP2005140755A (ja) * 2003-11-10 2005-06-02 Japan Science & Technology Agency 質量分析用プローブ及びそれを用いた質量分析方法
US20050148771A1 (en) 2004-01-05 2005-07-07 Applera Corporation. Active esters of N-substituted piperazine acetic acids, including isotopically enriched versions thereof
US20050148087A1 (en) 2004-01-05 2005-07-07 Applera Corporation Isobarically labeled analytes and fragment ions derived therefrom
US7355045B2 (en) 2004-01-05 2008-04-08 Applera Corporation Isotopically enriched N-substituted piperazine acetic acids and methods for the preparation thereof
US7666592B2 (en) 2004-02-18 2010-02-23 Ibis Biosciences, Inc. Methods for concurrent identification and quantification of an unknown bioagent
EP1623234B1 (de) 2004-03-01 2007-06-06 Applera Corporation Bestimmung von analytcharakteristika auf der grundlage von bindungseigenschaften
EP2458619B1 (de) 2004-05-24 2017-08-02 Ibis Biosciences, Inc. Massenspektrometrie mit selektivem Ionfilter durch digitale Schwelle
US20050266411A1 (en) 2004-05-25 2005-12-01 Hofstadler Steven A Methods for rapid forensic analysis of mitochondrial DNA
US20070048752A1 (en) 2004-07-12 2007-03-01 Applera Corporation Mass tags for quantitative analyses
US7811753B2 (en) 2004-07-14 2010-10-12 Ibis Biosciences, Inc. Methods for repairing degraded DNA
CA2575675A1 (en) 2004-07-30 2006-03-09 Adeza Biomedical Corporation Oncofetal fibronectin as a marker for disease and other conditions and methods for detection of oncofetal fibronectin
WO2006135400A2 (en) 2004-08-24 2006-12-21 Isis Pharmaceuticals, Inc. Methods for rapid identification of recombinant organisms
US20060183238A1 (en) 2005-02-09 2006-08-17 Applera Corporation Amine-containing compound analysis methods
US8182992B2 (en) 2005-03-03 2012-05-22 Ibis Biosciences, Inc. Compositions for use in identification of adventitious viruses
US8084207B2 (en) 2005-03-03 2011-12-27 Ibis Bioscience, Inc. Compositions for use in identification of papillomavirus
EP1904655A2 (de) 2005-07-21 2008-04-02 Isis Pharmaceuticals, Inc. Verfahren zur raschen identifizierung und quantifizierung von nukleinsäurevarianten
GB0515323D0 (en) 2005-07-26 2005-08-31 Electrophoretics Ltd Mass labels
GB0518585D0 (en) 2005-09-12 2005-10-19 Electrophoretics Ltd Mass labels
US8975404B2 (en) 2006-01-24 2015-03-10 Dh Technologies Development Pte. Ltd. Labeling reagents for analyte determination and methods and compounds used in making the same
US8088582B2 (en) 2006-04-06 2012-01-03 Ibis Biosciences, Inc. Compositions for the use in identification of fungi
JP5413836B2 (ja) 2006-05-26 2014-02-12 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド ヒドロキシル化化合物のためのタグ付け試薬およびその方法
US11098345B2 (en) 2006-06-05 2021-08-24 California Institute Of Technology Methods for detecting target analytes
US7906341B2 (en) 2006-06-30 2011-03-15 Dh Technologies Development Pte, Ltd. Methods, mixtures, kits and compositions pertaining to analyte determination
US8362242B2 (en) 2006-06-30 2013-01-29 Dh Technologies Development Pte. Ltd. Analyte determination utilizing mass tagging reagents comprising a non-encoded detectable label
US8048626B2 (en) 2006-07-28 2011-11-01 California Institute Of Technology Multiplex Q-PCR arrays
US11525156B2 (en) 2006-07-28 2022-12-13 California Institute Of Technology Multiplex Q-PCR arrays
US11560588B2 (en) 2006-08-24 2023-01-24 California Institute Of Technology Multiplex Q-PCR arrays
EP2064332B1 (de) 2006-09-14 2012-07-18 Ibis Biosciences, Inc. Gezielte gesamtgenomamplifizierung zur identifizierung von krankheitserregern
JP5680304B2 (ja) 2007-02-23 2015-03-04 アイビス バイオサイエンシズ インコーポレイティッド 迅速な法医学的ｄｎａ分析法
GB0704764D0 (en) 2007-03-12 2007-04-18 Electrophoretics Ltd Isobarically labelled reagents and methods of their use
US9598724B2 (en) 2007-06-01 2017-03-21 Ibis Biosciences, Inc. Methods and compositions for multiple displacement amplification of nucleic acids
CN101519698B (zh) * 2008-03-10 2013-05-22 周国华 一种利用序列标签定量测定核酸的方法
WO2017120148A1 (en) * 2016-01-04 2017-07-13 Quantumdx Group Limited Design, synthesis and use of synthetic nucleotides comprising charge mass tags
WO2010033599A2 (en) 2008-09-16 2010-03-25 Ibis Biosciences, Inc. Mixing cartridges, mixing stations, and related kits, systems, and methods
WO2010033625A1 (en) 2008-09-16 2010-03-25 Ibis Biosciences, Inc. Microplate handling systems and related computer program products and methods
EP2347254A2 (de) 2008-09-16 2011-07-27 Ibis Biosciences, Inc. Probenverarbeitungseinheiten, -systeme und damit verbundene verfahren
EP2396803A4 (de) 2009-02-12 2016-10-26 Ibis Biosciences Inc Ionisationssondenanordnungen
WO2010104798A1 (en) 2009-03-08 2010-09-16 Ibis Biosciences, Inc. Bioagent detection methods
WO2010104981A2 (en) 2009-03-10 2010-09-16 University Of Maryland Biotechnology Institute Deuterium isobaric tag reagents for quantitative analysis
WO2010114842A1 (en) 2009-03-30 2010-10-07 Ibis Biosciences, Inc. Bioagent detection systems, devices, and methods
EP2454000A4 (de) 2009-07-17 2016-08-10 Ibis Biosciences Inc Systeme zur identifizierung von biowirkstoffen
US8950604B2 (en) 2009-07-17 2015-02-10 Ibis Biosciences, Inc. Lift and mount apparatus
US9416409B2 (en) 2009-07-31 2016-08-16 Ibis Biosciences, Inc. Capture primers and capture sequence linked solid supports for molecular diagnostic tests
EP2462244B1 (de) 2009-08-06 2016-07-20 Ibis Biosciences, Inc. Basiszusammensetzungen ohne massebestimmung zur nukleinsäureerkennung
US9890408B2 (en) 2009-10-15 2018-02-13 Ibis Biosciences, Inc. Multiple displacement amplification
US9758840B2 (en) 2010-03-14 2017-09-12 Ibis Biosciences, Inc. Parasite detection via endosymbiont detection
ES2676183T3 (es) 2010-07-02 2018-07-17 Ventana Medical Systems, Inc. Detección de dianas usando marcas de masa y espectrometría de masas
US8492163B2 (en) 2011-01-31 2013-07-23 Dh Technologies Development Pte. Ltd. Methods, mixtures, kits and compositions pertaining to analyte determination
US9708647B2 (en) * 2015-03-23 2017-07-18 Insilixa, Inc. Multiplexed analysis of nucleic acid hybridization thermodynamics using integrated arrays
US20170089915A1 (en) * 2015-09-30 2017-03-30 Agilent Technologies, Inc. Methods of analyte derivatization and enhanced soft ionization
WO2017155858A1 (en) 2016-03-07 2017-09-14 Insilixa, Inc. Nucleic acid sequence identification using solid-phase cyclic single base extension
CN119510370A (zh) 2019-03-14 2025-02-25 因斯利克萨公司 基于时间门控的荧光检测的方法和系统
EP4240872A1 (de) * 2020-11-06 2023-09-13 Waters Technologies Corporation Verfahren und zusammensetzungen zur nukleinsäureanalyse
US20240290602A1 (en) * 2021-07-08 2024-08-29 Shimadzu Corporation Microorganism Mass Spectrometry Method
CN116496335B (zh) * 2023-03-21 2024-03-08 中国药科大学 一种修饰核苷酸及其应用
CN118980740B (zh) * 2024-09-19 2025-01-24 常州越泰检测科技有限公司 一种磁粉检测用喷照一体装置

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5547835A (en) * 1993-01-07 1996-08-20 Sequenom, Inc. DNA sequencing by mass spectrometry
GB9315847D0 (en) * 1993-07-30 1993-09-15 Isis Innovation Tag reagent and assay method
EP0735144B1 (de) * 1995-03-28 2002-06-05 Japan Science and Technology Corporation Verfahren zur molekularen Indexierung von Genen unter Verwendung von Restriktionsenzymen
CA2218188A1 (en) * 1995-04-11 1996-10-17 Trustees Of Boston University Solid phase sequencing of biopolymers
ATE191515T1 (de) * 1996-01-23 2000-04-15 Rapigene Inc Verfahren und zusammensetzungen zum analysieren von nukleinsäuremolekulen mittels bemessungstechniken
GB9618544D0 (en) * 1996-09-05 1996-10-16 Brax Genomics Ltd Characterising DNA

Also Published As

Publication number Publication date
JP2004357697A (ja) 2004-12-24
DE69836013D1 (de) 2006-11-09
WO1998031830A1 (en) 1998-07-23
CA2441655A1 (en) 1998-07-23
DE69838519D1 (de) 2007-11-15
EP0979305B1 (de) 2006-09-27
EP1400599A1 (de) 2004-03-24
NZ336769A (en) 2001-01-26
AU5570098A (en) 1998-08-07
EP0979305A1 (de) 2000-02-16
CN1250483A (zh) 2000-04-12
IL130885A0 (en) 2001-01-28
JP2006208400A (ja) 2006-08-10
IL130885A (en) 2005-05-17
EP1400599B1 (de) 2007-10-03
ATE374836T1 (de) 2007-10-15
JP3884087B2 (ja) 2007-02-21
CN100434531C (zh) 2008-11-19
AU725966B2 (en) 2000-10-26
CA2277786A1 (en) 1998-07-23
DE69836013T2 (de) 2007-05-24
DE69838519T2 (de) 2008-07-03
JP2001508307A (ja) 2001-06-26

Similar Documents

Publication Publication Date Title
ATE374836T1 (de) Massenmarkierte hybridisierungssonden
CY1113185T1 (el) Μεθοδοι συνενωσης αποδεκτη πεπτιδιου
DE69006394D1 (de) Organische elektrolumineszente Vorrichtung.
DE3877894D1 (de) Bio-lichtmessfuehler.
DE69012892D1 (de) Organische elektrolumineszente Vorrichtung.
DE3789182D1 (de) Sonde für Elektrophorese-Massenspektrometrie.
ES554046A0 (es) Un metodo para analizar el adn de un individuo.
FI873495L (fi) Foerstaerkt hybridiseringsanalys.
DK1627880T3 (da) Boronester og -syreforbindelser samt syntese og anvendelser
PT990047E (pt) Metodos e composicoes para a analise de acidos nucleicos por espectroscopia de massa.
DE3766189D1 (de) Pipettiervorrichtung.
ATE114651T1 (de) Alkynylamino-nukleotide.
FI880329L (fi) Fluoresenimmunobestaemning, till vilken energioeverfoering mellan tvao fluorofor anknyter sig.
DE3875354D1 (de) Fluoreszenzpolarisationsimmunassay fuer amphetamin/methamphetamin.
DK1329519T3 (da) Probe til diagnosticering af infektionssygdom, der skyldes Staphylococcus aureus
ATE174926T1 (de) Hydrophobe nukleinsäure-sonde
CA2337761A1 (en) ARYLSULPHONE-BASED BINDERS FOR MASS SPECTROMETRY ANALYSIS
DE3669043D1 (de) Testreagenzien.
DE69632643D1 (de) Verwendungen von nukleinsäuren die ein retrovirus aus schweinen entnommen sind
DE3854209D1 (de) Analyse von organischen Substanzen.
DE3879725D1 (de) Einrichtung fuer eine flache tastatur.
DK114387A (da) Fremgangsmaade til afproevning af en biologisk, nucleinsyreholdig proeve for tilstedevaerelsen af en specifik mikroorganisme
DE69018930D1 (de) Wandlerprüfung.
DE3788907D1 (de) Ablenkungsjoch mit wärmedissipierenden Mitteln für ein Oszilloskop.
FI851919A7 (fi) Menetelmä nukleotidien hybridisaation koettimen valmistamiseksi.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties