ATE338950T1 - Verfahren zum nachweis von allosteren effektoren eines rezeptors - Google Patents
Verfahren zum nachweis von allosteren effektoren eines rezeptorsInfo
- Publication number
- ATE338950T1 ATE338950T1 AT03748170T AT03748170T ATE338950T1 AT E338950 T1 ATE338950 T1 AT E338950T1 AT 03748170 T AT03748170 T AT 03748170T AT 03748170 T AT03748170 T AT 03748170T AT E338950 T1 ATE338950 T1 AT E338950T1
- Authority
- AT
- Austria
- Prior art keywords
- variation
- receptor
- kinetics
- detecting
- labeled
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 239000012637 allosteric effector Substances 0.000 title abstract 3
- 102000034287 fluorescent proteins Human genes 0.000 abstract 7
- 108091006047 fluorescent proteins Proteins 0.000 abstract 7
- 241000243321 Cnidaria Species 0.000 abstract 1
- 230000008033 biological extinction Effects 0.000 abstract 1
- 230000008512 biological response Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000010494 dissociation reaction Methods 0.000 abstract 1
- 230000005593 dissociations Effects 0.000 abstract 1
- 230000005284 excitation Effects 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 238000005259 measurement Methods 0.000 abstract 1
- 230000004962 physiological condition Effects 0.000 abstract 1
- 238000006862 quantum yield reaction Methods 0.000 abstract 1
- 230000004044 response Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06086—Dipeptides with the first amino acid being basic
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/557—Immunoassay; Biospecific binding assay; Materials therefor using kinetic measurement, i.e. time rate of progress of an antigen-antibody interaction
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Plural Heterocyclic Compounds (AREA)
- Auxiliary Devices For Music (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pyrane Compounds (AREA)
- Electrotherapy Devices (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0207436A FR2840993B1 (fr) | 2002-06-17 | 2002-06-17 | Procede de mise en evidence d'un effecteur allosterique d'un recepteur |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE338950T1 true ATE338950T1 (de) | 2006-09-15 |
Family
ID=29595303
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03748170T ATE338950T1 (de) | 2002-06-17 | 2003-06-16 | Verfahren zum nachweis von allosteren effektoren eines rezeptors |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20060194259A1 (de) |
| EP (1) | EP1514112B1 (de) |
| JP (1) | JP2005530158A (de) |
| AT (1) | ATE338950T1 (de) |
| AU (1) | AU2003267483A1 (de) |
| CA (1) | CA2489389A1 (de) |
| DE (1) | DE60308182T2 (de) |
| DK (1) | DK1514112T3 (de) |
| ES (1) | ES2273026T3 (de) |
| FR (1) | FR2840993B1 (de) |
| WO (1) | WO2003107004A2 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102007022915A1 (de) * | 2007-05-14 | 2008-11-20 | Stiftung Caesar Center Of Advanced European Studies And Research | Polymerisationssensor |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2764387B1 (fr) * | 1997-06-05 | 1999-07-23 | Centre Nat Rech Scient | Utilisation d'une proteine fluorescente pour la detection d'interactions entre une proteine cible et son ligand |
| AU2030000A (en) * | 1998-11-25 | 2000-06-13 | Cadus Pharmaceutical Corporation | Methods and compositions for identifying receptor effectors |
-
2002
- 2002-06-17 FR FR0207436A patent/FR2840993B1/fr not_active Expired - Fee Related
-
2003
- 2003-06-16 AT AT03748170T patent/ATE338950T1/de not_active IP Right Cessation
- 2003-06-16 ES ES03748170T patent/ES2273026T3/es not_active Expired - Lifetime
- 2003-06-16 US US10/518,298 patent/US20060194259A1/en not_active Abandoned
- 2003-06-16 CA CA002489389A patent/CA2489389A1/fr not_active Abandoned
- 2003-06-16 WO PCT/FR2003/001817 patent/WO2003107004A2/fr not_active Ceased
- 2003-06-16 DE DE60308182T patent/DE60308182T2/de not_active Expired - Fee Related
- 2003-06-16 DK DK03748170T patent/DK1514112T3/da active
- 2003-06-16 JP JP2004513772A patent/JP2005530158A/ja active Pending
- 2003-06-16 AU AU2003267483A patent/AU2003267483A1/en not_active Abandoned
- 2003-06-16 EP EP03748170A patent/EP1514112B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE60308182T2 (de) | 2007-08-23 |
| ES2273026T3 (es) | 2007-05-01 |
| EP1514112A2 (de) | 2005-03-16 |
| US20060194259A1 (en) | 2006-08-31 |
| FR2840993A1 (fr) | 2003-12-19 |
| JP2005530158A (ja) | 2005-10-06 |
| AU2003267483A1 (en) | 2003-12-31 |
| FR2840993B1 (fr) | 2005-04-08 |
| DE60308182D1 (de) | 2006-10-19 |
| EP1514112B1 (de) | 2006-09-06 |
| DK1514112T3 (da) | 2007-01-15 |
| WO2003107004A2 (fr) | 2003-12-24 |
| CA2489389A1 (fr) | 2003-12-24 |
| WO2003107004A3 (fr) | 2004-06-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1514112 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |