ES2177596T3 - Procedimiento para reducir la influencia de ensayos diagnosticos por parte de heparina con empleo de sales metalicas, y reactivo diagnosticopara ensayos diagnosticos para la determinacion de la capacidad de coagulacion de la sangre que contiene sales metalicas. - Google Patents

Procedimiento para reducir la influencia de ensayos diagnosticos por parte de heparina con empleo de sales metalicas, y reactivo diagnosticopara ensayos diagnosticos para la determinacion de la capacidad de coagulacion de la sangre que contiene sales metalicas.

Info

Publication number
ES2177596T3
ES2177596T3 ES95112267T ES95112267T ES2177596T3 ES 2177596 T3 ES2177596 T3 ES 2177596T3 ES 95112267 T ES95112267 T ES 95112267T ES 95112267 T ES95112267 T ES 95112267T ES 2177596 T3 ES2177596 T3 ES 2177596T3
Authority
ES
Spain
Prior art keywords
diagnostic tests
diagnostic
heparine
determination
influence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95112267T
Other languages
English (en)
Inventor
Karl Dr Fickenscher
Norbert Dr Zander
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics GmbH Germany
Original Assignee
Dade Behring Marburg GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6526227&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2177596(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Dade Behring Marburg GmbH filed Critical Dade Behring Marburg GmbH
Application granted granted Critical
Publication of ES2177596T3 publication Critical patent/ES2177596T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/38—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence, e.g. gluco- or galactomannans, e.g. Konjac gum, Locust bean gum, Guar gum
    • G01N2400/40—Glycosaminoglycans, i.e. GAG or mucopolysaccharides, e.g. chondroitin sulfate, dermatan sulfate, hyaluronic acid, heparin, heparan sulfate, and related sulfated polysaccharides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/108331—Preservative, buffer, anticoagulant or diluent
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25125—Digestion or removing interfering materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • General Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ecology (AREA)
  • Cell Biology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

SE DAN A CONOCER MEDIOS ADICIONALES PARA PRUEBAS DE DETERMINACION DE LA CAPACIDAD DE COAGULACION DE LA SANGRE, DE FORMA QUE ES POSIBLE EVITAR EL INFLUJO DE LA PRUEBA MEDIANTE HEPARINA O REDUCIRLA AL MENOS DE MANERA CONSIDERABLE. LOS MEDIOS ADICIONALES CONTIENEN UNA SAL METALICA, QUE DE MANERA PREFERENTE DE TRATA DE SALES DE COBRE O DE ZINC.
ES95112267T 1994-08-20 1995-08-04 Procedimiento para reducir la influencia de ensayos diagnosticos por parte de heparina con empleo de sales metalicas, y reactivo diagnosticopara ensayos diagnosticos para la determinacion de la capacidad de coagulacion de la sangre que contiene sales metalicas. Expired - Lifetime ES2177596T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4429660A DE4429660B4 (de) 1994-08-20 1994-08-20 Zusatzmittel für diagnostische Tests zur Bestimmung der Gerinnungsfähigkeit des Blutes, Verfahren zur Reduzierung der Beeinflussung von diagnostischen Tests durch Heparin und Verwendung von Metallsalzen zu diesen Zwecken

Publications (1)

Publication Number Publication Date
ES2177596T3 true ES2177596T3 (es) 2002-12-16

Family

ID=6526227

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95112267T Expired - Lifetime ES2177596T3 (es) 1994-08-20 1995-08-04 Procedimiento para reducir la influencia de ensayos diagnosticos por parte de heparina con empleo de sales metalicas, y reactivo diagnosticopara ensayos diagnosticos para la determinacion de la capacidad de coagulacion de la sangre que contiene sales metalicas.

Country Status (9)

Country Link
US (1) US5705396A (es)
EP (1) EP0697463B1 (es)
JP (1) JP3939771B2 (es)
KR (1) KR960008310A (es)
AT (1) ATE218166T1 (es)
AU (1) AU697417B2 (es)
CA (1) CA2156469C (es)
DE (2) DE4429660B4 (es)
ES (1) ES2177596T3 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6010911A (en) * 1997-04-30 2000-01-04 Medtronic, Inc. Apparatus for performing a heparin-independent high sensitivity platelet function evaluation technique
US6245573B1 (en) 1998-02-12 2001-06-12 University Of Medicine And Dentistry Of New Jersey Rapid assessment of the coagulant activity of blood
KR100527545B1 (ko) * 2000-12-28 2005-11-09 주식회사 하이닉스반도체 반도체 소자의 제조 방법
US7247488B2 (en) * 2003-05-06 2007-07-24 Medtronic, Inc. Method and kit for testing a multi-channel blood assay cartridge
DE102005028018A1 (de) * 2005-06-16 2006-12-21 Dade Behring Marburg Gmbh Verfahren zur Standardisierung von Gerinnungstesten
FR2934052B1 (fr) * 2008-07-17 2011-11-25 Stago Diagnostica Dosage de l'activite du facteur tissulaire circulant
EP2484775A1 (de) 2011-02-07 2012-08-08 Siemens Healthcare Diagnostics Products GmbH Heparin-insensitives Verfahren zur Bestimmung von direkten Gerinnungsfaktorinhibitoren
EP2711711A1 (en) * 2012-09-19 2014-03-26 Technoclone GmbH Method for determining the direct thrombin inhibitor concentration in a plasma sample
JP6577778B2 (ja) * 2015-07-30 2019-09-18 シスメックス株式会社 凝固時間の測定方法およびその装置、凝固時間測定用試薬ならびに試薬キット
JP6595247B2 (ja) 2015-07-30 2019-10-23 シスメックス株式会社 凝固時間の測定方法およびその装置、凝固時間測定用試薬ならびに試薬キット
US11378577B2 (en) 2015-10-30 2022-07-05 Lsi Medience Corporation Reagent and method for measuring thrombin-antithrombin complex

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4199502A (en) 1978-08-04 1980-04-22 Warner-Lambert Company Removal of heparin from blood plasma samples using an insoluble protamine reaction product
US4226599A (en) * 1979-06-20 1980-10-07 Warner-Lambert Company Removal of heparin from heparin-containing blood plasma samples using a triethylaminoethyl cellulose tablet
US4250041A (en) * 1979-06-25 1981-02-10 Warner-Lambert Company Removal of heparin from blood plasma samples using an insoluble protamine reaction product
SE8702254D0 (sv) * 1987-05-29 1987-05-29 Kabivitrum Ab Novel heparin derivatives
WO1989012692A1 (en) 1988-06-06 1989-12-28 Massachusetts Institute Of Technology Large scale method for purification of high purity heparinase
US5055412A (en) * 1989-03-21 1991-10-08 Proksch Gary J Factor sensitive reagent for testing of blood coagulation containing ellagic acid and divalent metal ions and method of making the same
US5000854A (en) 1989-06-14 1991-03-19 The University Of Michigan Protamine-based filter device for removal of heparin from blood samples
WO1991016453A1 (en) * 1990-04-17 1991-10-31 Analytical Control Systems, Inc. Coagulation assays and reagents
US5151192A (en) * 1990-07-13 1992-09-29 Pall Corporation Method for removing heparin from blood or plasma
US5286388A (en) * 1991-06-20 1994-02-15 Ingram John M Method for neutralizing heparin in whole blood taken from an extracorporeal circuit

Also Published As

Publication number Publication date
CA2156469C (en) 2008-01-15
DE4429660B4 (de) 2004-02-12
AU697417B2 (en) 1998-10-08
KR960008310A (ko) 1996-03-22
US5705396A (en) 1998-01-06
JPH0868794A (ja) 1996-03-12
CA2156469A1 (en) 1996-02-21
AU3015095A (en) 1996-03-07
EP0697463B1 (de) 2002-05-29
JP3939771B2 (ja) 2007-07-04
DE59510217D1 (de) 2002-07-04
EP0697463A1 (de) 1996-02-21
ATE218166T1 (de) 2002-06-15
DE4429660A1 (de) 1996-02-22

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