ATE334667T1 - Alanin- und glycin-haltige arzneien gegen hepatitis - Google Patents
Alanin- und glycin-haltige arzneien gegen hepatitisInfo
- Publication number
- ATE334667T1 ATE334667T1 AT01900685T AT01900685T ATE334667T1 AT E334667 T1 ATE334667 T1 AT E334667T1 AT 01900685 T AT01900685 T AT 01900685T AT 01900685 T AT01900685 T AT 01900685T AT E334667 T1 ATE334667 T1 AT E334667T1
- Authority
- AT
- Austria
- Prior art keywords
- alanine
- glycine
- against hepatitis
- glycine containing
- containing medications
- Prior art date
Links
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 title abstract 8
- 239000004471 Glycine Substances 0.000 title abstract 4
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 title abstract 3
- 235000004279 alanine Nutrition 0.000 title abstract 3
- 208000006454 hepatitis Diseases 0.000 title abstract 2
- 231100000283 hepatitis Toxicity 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- MSWZFWKMSRAUBD-GASJEMHNSA-N 2-amino-2-deoxy-D-galactopyranose Chemical compound N[C@H]1C(O)O[C@H](CO)[C@H](O)[C@@H]1O MSWZFWKMSRAUBD-GASJEMHNSA-N 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- MSWZFWKMSRAUBD-UHFFFAOYSA-N beta-D-galactosamine Natural products NC1C(O)OC(CO)C(O)C1O MSWZFWKMSRAUBD-UHFFFAOYSA-N 0.000 abstract 1
- 230000030833 cell death Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000001553 hepatotropic effect Effects 0.000 abstract 1
- 230000010534 mechanism of action Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000008658 | 2000-01-18 | ||
| JP2000060097 | 2000-03-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE334667T1 true ATE334667T1 (de) | 2006-08-15 |
Family
ID=26583682
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01900685T ATE334667T1 (de) | 2000-01-18 | 2001-01-12 | Alanin- und glycin-haltige arzneien gegen hepatitis |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7208523B2 (de) |
| EP (1) | EP1249235B1 (de) |
| AT (1) | ATE334667T1 (de) |
| AU (1) | AU2001225499A1 (de) |
| DE (1) | DE60121913T2 (de) |
| ES (1) | ES2264437T3 (de) |
| WO (1) | WO2001052834A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1656933A1 (de) * | 2004-11-11 | 2006-05-17 | Ajinomoto Co., Inc. | Medizinische Zusammensetzung enthaltend L-Alanin zur Behandlung von nichtalkoholischer Fettlebererkrankung und/oder nichtalkoholischer Steatohepatitis |
| EP1829540A4 (de) * | 2004-12-10 | 2008-04-02 | Ajinomoto Kk | Zusammensetzung zur prävention/behandlung von leberkrankheiten |
| JPWO2007142297A1 (ja) * | 2006-06-09 | 2009-10-29 | 味の素株式会社 | 肝疾患予防・治療用組成物 |
| GB201019628D0 (en) * | 2010-11-19 | 2010-12-29 | Reckitt Benckiser Nv | Dyed coated bleach materials |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS51115909A (en) * | 1975-04-01 | 1976-10-13 | Otsuka Pharmaceut Factory Inc | A process for preparing amino acid parenteral injection mixed with a r educing sugar |
| DE2636828A1 (de) * | 1976-08-16 | 1978-02-23 | Fresenius Chem Pharm Ind | L-amonosaeurengemische fuer die behandlung von leberinsuffizienz sowie die herstellung derartiger gemische |
| JPS58126767A (ja) * | 1982-01-22 | 1983-07-28 | Ajinomoto Co Inc | 肝臓病患者用栄養組成物 |
| US4491589A (en) * | 1982-05-17 | 1985-01-01 | The Trustees Of Columbia University In The City Of New York | Amino acid solutions for parenteral nutrition and methods of formulation and use |
| SU1470739A1 (ru) * | 1984-07-16 | 1989-04-07 | Всесоюзный кардиологический научный центр АМН СССР | Гексапептид, обладающий гепатопротективным действием |
| JP3127484B2 (ja) * | 1991-02-28 | 2001-01-22 | 味の素株式会社 | 肝炎治療薬 |
| CA2078712A1 (en) * | 1991-09-23 | 1993-03-24 | Bernhard Sixt | Composition comprising amino acids for the prevention of hypoxic damage and a process for its preparation |
| JP3168669B2 (ja) * | 1992-02-26 | 2001-05-21 | 味の素株式会社 | 肝再生促進剤 |
| GB9512100D0 (en) * | 1995-06-14 | 1995-08-09 | Sandoz Nutrition Ltd | Improvements in or relating to organic compounds |
-
2001
- 2001-01-12 EP EP01900685A patent/EP1249235B1/de not_active Expired - Lifetime
- 2001-01-12 AT AT01900685T patent/ATE334667T1/de not_active IP Right Cessation
- 2001-01-12 ES ES01900685T patent/ES2264437T3/es not_active Expired - Lifetime
- 2001-01-12 AU AU2001225499A patent/AU2001225499A1/en not_active Abandoned
- 2001-01-12 DE DE60121913T patent/DE60121913T2/de not_active Expired - Lifetime
- 2001-01-12 WO PCT/JP2001/000109 patent/WO2001052834A1/ja not_active Ceased
-
2002
- 2002-07-18 US US10/196,816 patent/US7208523B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1249235A4 (de) | 2004-07-28 |
| DE60121913D1 (de) | 2006-09-14 |
| US20020198262A1 (en) | 2002-12-26 |
| US7208523B2 (en) | 2007-04-24 |
| ES2264437T3 (es) | 2007-01-01 |
| EP1249235A1 (de) | 2002-10-16 |
| WO2001052834A1 (en) | 2001-07-26 |
| AU2001225499A1 (en) | 2001-07-31 |
| DE60121913T2 (de) | 2007-03-01 |
| EP1249235B1 (de) | 2006-08-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1249235 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |