BR9913951A - Tratamento de infecção de hepatite b com timosina alfa 1 em combinação com lamivudina e flamciclovir - Google Patents
Tratamento de infecção de hepatite b com timosina alfa 1 em combinação com lamivudina e flamciclovirInfo
- Publication number
- BR9913951A BR9913951A BR9913951-0A BR9913951A BR9913951A BR 9913951 A BR9913951 A BR 9913951A BR 9913951 A BR9913951 A BR 9913951A BR 9913951 A BR9913951 A BR 9913951A
- Authority
- BR
- Brazil
- Prior art keywords
- lamivudine
- hepatitis
- infection
- treatment
- flamciclovir
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2292—Thymosin; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
Resumo da Patente de Invenção para: <B>''TRATAMENTO DE INFECçãO DE HEPATITE B COM TIMOSINA ALFA 1 EM COMBINAçãO COM LAMIVUDINA OU EM COMBINAçãO COM LAMIVUDINA E FAMCICLOVIR''<D> Tratamento de infecção por vírus da hepatite B, em um paciente, por administração, ao paciente, de um regime de droga incluindo uma quantidade eficaz anti-viral de timosina alfa 1 (T<244>1), uma quantidade eficaz anti-viral de lamivudina e, opcionalmente, uma quantidade eficaz anti-viral de famciclovir.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10177198P | 1998-09-25 | 1998-09-25 | |
US09/168,869 US6288033B1 (en) | 1998-09-25 | 1998-10-09 | Treatment of hepatitis B infection with thymosin alpha 1 in combination with lamivudine or in combination with lamivudine and famciclovir |
PCT/US1999/021954 WO2000018417A2 (en) | 1998-09-25 | 1999-09-22 | Treatment of hepatitis b infection with thymosin alpha 1 and lamivudine |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9913951A true BR9913951A (pt) | 2001-06-12 |
Family
ID=26798617
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9913951-0A BR9913951A (pt) | 1998-09-25 | 1999-09-22 | Tratamento de infecção de hepatite b com timosina alfa 1 em combinação com lamivudina e flamciclovir |
Country Status (16)
Country | Link |
---|---|
US (1) | US6288033B1 (pt) |
EP (1) | EP1115420B1 (pt) |
JP (1) | JP2002525333A (pt) |
CN (1) | CN1183964C (pt) |
AT (1) | ATE220332T1 (pt) |
AU (1) | AU757833B2 (pt) |
BR (1) | BR9913951A (pt) |
CA (1) | CA2345462A1 (pt) |
DE (1) | DE69902103T2 (pt) |
DK (1) | DK1115420T3 (pt) |
ES (1) | ES2181502T3 (pt) |
HK (1) | HK1041215B (pt) |
MX (1) | MXPA01003105A (pt) |
PT (1) | PT1115420E (pt) |
TR (1) | TR200100845T2 (pt) |
WO (1) | WO2000018417A2 (pt) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2003039582A (ja) * | 2001-07-19 | 2003-02-13 | Three M Innovative Properties Co | 湿潤防滑性シート及び湿潤防滑構造体 |
US6855346B2 (en) * | 2001-10-05 | 2005-02-15 | Tzu-Sheng Wu | Pharmaceutical composition having prophylactic effects on lamivudine-related disease relapse and drug resistance and methods of using the same |
PL370453A1 (en) * | 2001-10-26 | 2005-05-30 | Rhode Island Hospital | Thymosin augmentation of genetic immunization |
US20060259603A1 (en) * | 2005-05-16 | 2006-11-16 | Shrader Anthony G | User based - workflow and business process management |
WO2007037790A2 (en) * | 2005-06-08 | 2007-04-05 | Elan Corporation, Plc | Modified release famciclovir compositions |
MX2008013872A (es) * | 2006-05-02 | 2008-11-14 | Sigma Tau Ind Farmaceuti | Uso de timosina alfa 1, sola o en combinacion con ptx3 o ganciclovir, para el tratamiento de infeccion por citomegalovirus. |
ES2288118B1 (es) * | 2006-05-10 | 2008-11-01 | Bcn Peptides, S.A. | Procedimiento para sintetizar timosinas. |
US8716012B2 (en) * | 2009-05-08 | 2014-05-06 | Sciclone Pharmaceuticals, Inc. | Alpha thymosin peptides as vaccine enhancers |
CA2826875A1 (en) * | 2011-02-09 | 2012-08-16 | Sciclone Pharmaceuticals, Inc. | Thymosin alpha peptide for preventing, reducing the severity of, and treating infection |
JP2016507569A (ja) * | 2013-02-07 | 2016-03-10 | トビラ セラピューティクス, インコーポレイテッド | ラミブジン結晶塩 |
US11136378B2 (en) * | 2015-11-30 | 2021-10-05 | HBVtech LLC | Methods of curing HBV infection and providing complete protection against HBV infection |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8904855D0 (en) | 1989-03-03 | 1989-04-12 | Beecham Group Plc | Pharmaceutical treatment |
US5308833A (en) | 1992-02-06 | 1994-05-03 | Sciclone Pharmaceuticals | Method for treating hepatitis B carriers with minimal disease |
EP0627930A4 (en) | 1992-07-13 | 1997-08-20 | Kenneth E Sherman | COMPOSITION AND METHOD FOR TREATING HEPATITIS B. |
US5939423A (en) | 1997-04-16 | 1999-08-17 | Sciclone Pharmaceuticals, Inc. | Treatment of hepatitis B infection with thymosin alpha 1 and famciclovir |
-
1998
- 1998-10-09 US US09/168,869 patent/US6288033B1/en not_active Expired - Fee Related
-
1999
- 1999-09-22 CN CNB998113824A patent/CN1183964C/zh not_active Expired - Lifetime
- 1999-09-22 CA CA002345462A patent/CA2345462A1/en not_active Abandoned
- 1999-09-22 BR BR9913951-0A patent/BR9913951A/pt not_active Application Discontinuation
- 1999-09-22 PT PT99969679T patent/PT1115420E/pt unknown
- 1999-09-22 ES ES99969679T patent/ES2181502T3/es not_active Expired - Lifetime
- 1999-09-22 DE DE69902103T patent/DE69902103T2/de not_active Expired - Lifetime
- 1999-09-22 MX MXPA01003105A patent/MXPA01003105A/es active IP Right Grant
- 1999-09-22 AU AU60570/99A patent/AU757833B2/en not_active Ceased
- 1999-09-22 TR TR2001/00845T patent/TR200100845T2/xx unknown
- 1999-09-22 EP EP99969679A patent/EP1115420B1/en not_active Expired - Lifetime
- 1999-09-22 WO PCT/US1999/021954 patent/WO2000018417A2/en active IP Right Grant
- 1999-09-22 AT AT99969679T patent/ATE220332T1/de active
- 1999-09-22 DK DK99969679T patent/DK1115420T3/da active
- 1999-09-22 JP JP2000571935A patent/JP2002525333A/ja not_active Withdrawn
-
2002
- 2002-04-16 HK HK02102845.1A patent/HK1041215B/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU6057099A (en) | 2000-04-17 |
US6288033B1 (en) | 2001-09-11 |
TR200100845T2 (tr) | 2001-10-22 |
HK1041215B (zh) | 2005-08-26 |
DE69902103T2 (de) | 2003-02-27 |
CN1183964C (zh) | 2005-01-12 |
CA2345462A1 (en) | 2000-04-06 |
EP1115420B1 (en) | 2002-07-10 |
JP2002525333A (ja) | 2002-08-13 |
ATE220332T1 (de) | 2002-07-15 |
MXPA01003105A (es) | 2003-05-15 |
EP1115420A2 (en) | 2001-07-18 |
ES2181502T3 (es) | 2003-02-16 |
PT1115420E (pt) | 2002-11-29 |
DE69902103D1 (de) | 2002-08-14 |
DK1115420T3 (da) | 2002-11-04 |
WO2000018417A3 (en) | 2000-07-06 |
WO2000018417A2 (en) | 2000-04-06 |
HK1041215A1 (en) | 2002-07-05 |
CN1320041A (zh) | 2001-10-31 |
AU757833B2 (en) | 2003-03-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PT956861E (pt) | Terapia combinada compreendendo ribavirina e interferao alfa em doentes sem tratamento antiviral anterior tendo infeccao cronica pelo virus da hepatite c | |
MY133891A (en) | Polyethylene glycol modified interferon therapy | |
MY141594A (en) | 3'-PRODRUGS OF 2'-DEOXY-ß-L-NUCLEOSIDES | |
DE60131250T8 (de) | Nucleosid-analoga mit monozyklischen basischen carboxamidingruppen | |
TR200402565T4 (tr) | Hepatit delta virüsü enfeksiyonunun tedavi edilmesinde ß-L-2'-deoksi-nükleosidlerin kullanımı | |
RS20120201A3 (en) | METHODS AND MIXTURES FOR TREATMENT OF VIRAL HEPATITIS C | |
DK0831852T3 (da) | Nukleosider med anti-hepatitis B-virusaktivitet | |
CO4970691A1 (es) | Terapia en combinacion para erradicar vhc-arn detectable en pacientes que padecen infeccion de hepatitis c cronica | |
AR021876A1 (es) | Terapia de combinacion para vhc por induccion de ribavirina - interferon alfa pegilado | |
BR9913951A (pt) | Tratamento de infecção de hepatite b com timosina alfa 1 em combinação com lamivudina e flamciclovir | |
TR200101085T2 (tr) | Kronik hepatit C enfeksiyonlu hastalarda algılanabilir HCV-RNA'nın yok edilmesi için birleşik ribavirin-interferon alfa tedavisi | |
ATE339211T1 (de) | L-fmau zur behandlung von hepatitis-delta-virus- infizierung | |
MD990258A (en) | Method of treatment of the acute viral hepatitis B | |
FI954127A0 (fi) | Menetelmä C-hepatiitin hoitamiseksi interferonihoitoon reagoimattomissa potilaissa | |
ATE348628T1 (de) | Behandlung von hepatitis c mit thymosin, interferon und ribavirin | |
MXPA94003453A (es) | Metodo y composicion para el tratamiento de pacientes con hepatitis b que tienen descompensacion hepatica. | |
RU98109203A (ru) | Способ лечения вирусного гепатита b у детей | |
ATE332704T1 (de) | Behandlung von hepatitis c mit thymosin und pegyliertem interferon |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O E 10 (VIII) DA LPI. |
|
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |