ATE327748T1 - Alkandiol derivate zur behandlung von knochenkrankheiten - Google Patents

Alkandiol derivate zur behandlung von knochenkrankheiten

Info

Publication number
ATE327748T1
ATE327748T1 AT02777456T AT02777456T ATE327748T1 AT E327748 T1 ATE327748 T1 AT E327748T1 AT 02777456 T AT02777456 T AT 02777456T AT 02777456 T AT02777456 T AT 02777456T AT E327748 T1 ATE327748 T1 AT E327748T1
Authority
AT
Austria
Prior art keywords
inhibit
esters
activity
compounds
independently
Prior art date
Application number
AT02777456T
Other languages
German (de)
English (en)
Inventor
Stuart Ralston
Iain Robert Greig
T Hof Robert Jurgen Van
Kenneth John Armour
Original Assignee
Univ Aberdeen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Aberdeen filed Critical Univ Aberdeen
Application granted granted Critical
Publication of ATE327748T1 publication Critical patent/ATE327748T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT02777456T 2001-10-31 2002-10-31 Alkandiol derivate zur behandlung von knochenkrankheiten ATE327748T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0126157.7A GB0126157D0 (en) 2001-10-31 2001-10-31 Therapeutic compounds

Publications (1)

Publication Number Publication Date
ATE327748T1 true ATE327748T1 (de) 2006-06-15

Family

ID=9924891

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02777456T ATE327748T1 (de) 2001-10-31 2002-10-31 Alkandiol derivate zur behandlung von knochenkrankheiten

Country Status (9)

Country Link
US (1) US7745424B2 (enExample)
EP (1) EP1441716B1 (enExample)
JP (1) JP2005511556A (enExample)
KR (1) KR20050042044A (enExample)
AT (1) ATE327748T1 (enExample)
CA (1) CA2465399A1 (enExample)
DE (1) DE60211935T2 (enExample)
GB (1) GB0126157D0 (enExample)
WO (1) WO2003037321A1 (enExample)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060177416A1 (en) 2003-10-14 2006-08-10 Medivas, Llc Polymer particle delivery compositions and methods of use
US20060286064A1 (en) * 2000-08-30 2006-12-21 Medivas, Llc Therapeutic polymers and methods
ATE380025T1 (de) 2003-05-07 2007-12-15 Univ Aberdeen Ketone und reduzierte ketone als therapeutische mittel zur behandlung von knochenerkrankungen
US20060188469A1 (en) * 2003-10-14 2006-08-24 Medivas, Llc Vaccine delivery compositions and methods of use
KR20060048138A (ko) 2004-05-28 2006-05-18 가부시키가이샤 닛폰 쇼쿠바이 불소 함유 화합물
GB0412553D0 (en) 2004-06-04 2004-07-07 Univ Aberdeen Therapeutic agents for the treatment of bone conditions
US20070053984A1 (en) * 2005-03-03 2007-03-08 Monique Spann-Wade Topical gels compositions
JP5178520B2 (ja) 2005-09-22 2013-04-10 メディバス エルエルシー 固体ポリマー送達組成物およびその使用法
EP1926780B1 (en) 2005-09-22 2013-08-14 Medivas, LLC Bis-( -amino)-diol-diester-containing poly(ester amide) and poly(ester urethane) compositions and methods of use
US20080317684A1 (en) * 2006-09-06 2008-12-25 Isw Group, Inc. Topical Compositions
GB0705400D0 (en) * 2007-03-21 2007-05-02 Univ Aberdeen Therapeutic compounds andm their use
GB0817207D0 (en) 2008-09-19 2008-10-29 Pimco 2664 Ltd therapeutic apsac compounds and their use
GB0817208D0 (en) 2008-09-19 2008-10-29 Pimco 2664 Ltd Therapeutic apsap compounds and their use
WO2010036973A1 (en) * 2008-09-25 2010-04-01 Comgenrx, Inc. Treatment of hyperproliferative disorders using cardiac glycosides
EP3159368B1 (en) 2011-06-23 2024-07-24 DSM IP Assets B.V. New biodegradable polyesteramide copolymers for drug delivery
US9873765B2 (en) 2011-06-23 2018-01-23 Dsm Ip Assets, B.V. Biodegradable polyesteramide copolymers for drug delivery
WO2013010400A1 (zh) * 2011-07-21 2013-01-24 Hou Wenge 一种基于布洛芬的化合物及其制备方法和应用及药物制剂
WO2014039042A1 (en) 2012-09-06 2014-03-13 Northeastern University Novel cannabinergic compounds and uses thereof
US11964956B2 (en) 2012-09-06 2024-04-23 Northeastern University Cannabinergic compounds and uses thereof
WO2014134127A1 (en) 2013-02-26 2014-09-04 Northeastern University Cannabinergic nitrate esters and related analogs
EP2818531B1 (en) * 2013-06-25 2017-07-26 Merck Patent GmbH Polymerisable compounds and the use thereof in liquid-crystal displays
GB201311361D0 (en) 2013-06-26 2013-08-14 Pimco 2664 Ltd Compounds and their therapeutic use
CA2970578C (en) 2014-12-17 2024-01-02 Pimco 2664 Limited N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamide and n-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)-benzenesulfonamide compounds and their therapeutic use
AU2015366355B2 (en) 2014-12-18 2020-05-28 Dsm Ip Assets B.V. Drug delivery system for delivery of acid sensitive drugs
CN113402386B (zh) * 2021-05-28 2024-05-03 武汉亿科德精细化工有限公司 一种新戊二醇二苯甲酸酯的合成方法
WO2024083934A1 (en) 2022-10-19 2024-04-25 Basf Se Method for preparing 1,4-butanediol diesters

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB663072A (en) 1947-05-24 1951-12-19 British Celanese Improvements relating to compositions comprising organic thermoplastic substances
GB661185A (en) 1947-11-24 1951-11-21 Sterling Drug Inc Improvements in or relating to the production of alkoxyalkyl esters of iodobenzoic acids
GB716877A (en) 1951-07-25 1954-10-13 British Celanese Improvements in polyesters and their intermediates
GB774180A (en) 1953-11-18 1957-05-08 Cecil Reginald Burch Grading or separation of solid materials in liquid suspension
GB774635A (en) 1954-06-29 1957-05-15 Thomae Gmbh Dr K New benzoic acid derivatives, and processes for their preparation
JPS4326316Y1 (enExample) 1964-11-21 1968-11-01
CH496647A (de) 1967-12-15 1970-09-30 Hoechst Ag Verfahren zur Herstellung von Terephthalsäure-(B-hydroxy-äthyl)-estern
US3689535A (en) 1968-09-26 1972-09-05 John Kollar Process for preparing ethylene glycol esters
US3715389A (en) 1971-03-01 1973-02-06 Halcon International Inc Process for preparing glycol esters from olefinically unsaturated compounds
DE2602030C2 (de) 1976-01-21 1983-12-01 Henkel KGaA, 4000 Düsseldorf Diphosphonoalkancarbonsäuren und Verfahren zu deren Herstellung
JP2748005B2 (ja) 1988-10-13 1998-05-06 旭電化工業株式会社 光学活性ビフェニル化合物および該化合物含有液晶組成物
IT1256450B (it) * 1992-11-26 1995-12-05 Soldato Piero Del Esteri nitrici con attivita' farmacologica e procedimento per la loro preparazione
US5374707A (en) * 1993-02-18 1994-12-20 Monsanto Company Hydroxy ethyl bibenzoate
JP3538444B2 (ja) * 1993-09-30 2004-06-14 株式会社三光開発科学研究所 ジヒドロキシ化合物およびその製造方法
US6124474A (en) 1999-12-21 2000-09-26 Abbott Laboratories Synthesis of chiral 2-azetidinemethanol compounds
JP4326316B2 (ja) 2003-12-09 2009-09-02 日産自動車株式会社 車両のトラクションコントロール装置

Also Published As

Publication number Publication date
DE60211935D1 (de) 2006-07-06
WO2003037321A1 (en) 2003-05-08
EP1441716B1 (en) 2006-05-31
KR20050042044A (ko) 2005-05-04
JP2005511556A (ja) 2005-04-28
EP1441716A1 (en) 2004-08-04
CA2465399A1 (en) 2003-05-08
US7745424B2 (en) 2010-06-29
DE60211935T2 (de) 2007-01-11
US20040254151A1 (en) 2004-12-16
GB0126157D0 (en) 2002-01-02

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