ATE318909T1 - Konstitutive expression von nicht-infektiöser hiv-ähnlicher teilchen - Google Patents

Konstitutive expression von nicht-infektiöser hiv-ähnlicher teilchen

Info

Publication number
ATE318909T1
ATE318909T1 AT98960976T AT98960976T ATE318909T1 AT E318909 T1 ATE318909 T1 AT E318909T1 AT 98960976 T AT98960976 T AT 98960976T AT 98960976 T AT98960976 T AT 98960976T AT E318909 T1 ATE318909 T1 AT E318909T1
Authority
AT
Austria
Prior art keywords
particles
hiv
constitutive expression
modified
genome
Prior art date
Application number
AT98960976T
Other languages
German (de)
English (en)
Inventor
Benjamin Rovinski
Fei-Long Yao
Shi Xian Cao
Original Assignee
Aventis Pasteur
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25537545&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE318909(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aventis Pasteur filed Critical Aventis Pasteur
Application granted granted Critical
Publication of ATE318909T1 publication Critical patent/ATE318909T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16023—Virus like particles [VLP]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16311—Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
    • C12N2740/16322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • AIDS & HIV (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT98960976T 1997-12-16 1998-12-14 Konstitutive expression von nicht-infektiöser hiv-ähnlicher teilchen ATE318909T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/991,773 US6121021A (en) 1997-12-16 1997-12-16 Constitutive expression of non-infectious HIV-like particles

Publications (1)

Publication Number Publication Date
ATE318909T1 true ATE318909T1 (de) 2006-03-15

Family

ID=25537545

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98960976T ATE318909T1 (de) 1997-12-16 1998-12-14 Konstitutive expression von nicht-infektiöser hiv-ähnlicher teilchen

Country Status (12)

Country Link
US (2) US6121021A (cg-RX-API-DMAC7.html)
EP (1) EP1038001B8 (cg-RX-API-DMAC7.html)
JP (1) JP2004509601A (cg-RX-API-DMAC7.html)
AT (1) ATE318909T1 (cg-RX-API-DMAC7.html)
AU (1) AU749174B2 (cg-RX-API-DMAC7.html)
BR (1) BR9813626A (cg-RX-API-DMAC7.html)
CA (1) CA2312943C (cg-RX-API-DMAC7.html)
DE (1) DE69833686T2 (cg-RX-API-DMAC7.html)
DK (1) DK1038001T3 (cg-RX-API-DMAC7.html)
ES (1) ES2262250T3 (cg-RX-API-DMAC7.html)
PT (1) PT1038001E (cg-RX-API-DMAC7.html)
WO (1) WO1999031250A2 (cg-RX-API-DMAC7.html)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6080408A (en) * 1994-08-22 2000-06-27 Connaught Laboratories Limited Human immunodeficiency virus type 1 nucleic acids devoid of long terminal repeats capable of encoding for non-infectious, immunogenic, retrovirus-like particles
US7135191B2 (en) * 1997-09-04 2006-11-14 Zsolt Istvan Hertelendy Urogenital or anorectal transmucosal vaccine delivery system
US6121021A (en) * 1997-12-16 2000-09-19 Connaught Laboratories Limited Constitutive expression of non-infectious HIV-like particles
EP1083230A1 (en) * 1999-09-10 2001-03-14 Academisch Medisch Centrum Amsterdam Viral replicons and viruses dependent on inducing agents
US20040105871A1 (en) * 2000-03-02 2004-06-03 Robinson Harriet L. Compositions and methods for generating an immune response
EP2388015A1 (en) 2000-03-02 2011-11-23 Emory University DNA expression vectors and methods of use
WO2002072754A2 (en) * 2001-03-08 2002-09-19 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Mva expressing modified hiv envelope, gag, and pol genes
US8623379B2 (en) * 2000-03-02 2014-01-07 Emory University Compositions and methods for generating an immune response
EP1280551B1 (en) * 2000-04-27 2007-01-10 Sanofi Pasteur Limited Vaccines against hiv infection
EP1776961A1 (en) * 2000-04-27 2007-04-25 Sanofi Pasteur Limited Immunizing against HIV infection
US7122180B2 (en) * 2000-10-23 2006-10-17 Children's Medical Center Corporation DNA vectors containing mutated HIV proviruses
WO2004042001A2 (en) * 2002-05-17 2004-05-21 Emory University Virus-like particles, methods of preparation, and immonogenic compositions
US9045727B2 (en) * 2002-05-17 2015-06-02 Emory University Virus-like particles, methods of preparation, and immunogenic compositions
EP2055316A1 (en) * 2003-09-09 2009-05-06 VIRxSYS Corporation Lentivirus vector-based approaches for generating an immune response to HIV in humans
US20090257983A1 (en) * 2008-04-11 2009-10-15 Scheiber Lane Bernard Medical treatment device for treating aids by utilizing modified human immunodeficiency virus virions to insert anti-viral medications into t-helper cells
US20110293693A1 (en) * 2010-05-31 2011-12-01 Scheiber Lane Bernard Quantum unit of inheritance vector therapy
US20110293694A1 (en) * 2010-05-31 2011-12-01 Scheiber Lane Bernard Quantum unit of inheritance vector therapy method
EP3173096A1 (en) 2011-04-06 2017-05-31 Biovaxim Limited Pharmaceutical compositions for preventing and/or treating an hiv disease in humans

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5001230A (en) * 1988-02-18 1991-03-19 Schering Corporation T cell activation markers
GB8923123D0 (en) * 1989-10-13 1989-11-29 Connaught Lab A vaccine for human immunodeficiency virus
CA2067778A1 (en) * 1989-10-16 1991-04-17 The Whitehead Institute For Biomedical Research Non-infectious hiv-1 particles and uses therefor
WO1991007425A1 (en) * 1989-11-20 1991-05-30 Oncogen Limited Partnership Non-replicating recombinant-made retroviral particles used as antiviral agents and immunogens
JP3494300B2 (ja) 1990-04-03 2004-02-09 ジェネンテック・インコーポレーテッド Ｈｉｖに対する予防接種のための方法および組成物
JPH08500005A (ja) * 1992-03-27 1996-01-09 ホワイトヘッド インスティチュート フォー バイオメディカル リサーチ 非感染性ｈｉｖ粒子およびその用途
CA2164505A1 (en) * 1993-06-07 1994-12-22 Phillip W. Berman Hiv envelope polypeptides
KR960703136A (ko) * 1993-06-09 1996-06-19 미첼 클레인 탠덤 합성 hiv-1 펩티드들
US6080408A (en) * 1994-08-22 2000-06-27 Connaught Laboratories Limited Human immunodeficiency virus type 1 nucleic acids devoid of long terminal repeats capable of encoding for non-infectious, immunogenic, retrovirus-like particles
AU725143B2 (en) * 1996-10-17 2000-10-05 Oxford Biomedica (Uk) Limited Retroviral vectors
JP4312265B2 (ja) * 1997-04-09 2009-08-12 ラング−ジ チャン ワクチン評価のための動物モデル
US6121021A (en) * 1997-12-16 2000-09-19 Connaught Laboratories Limited Constitutive expression of non-infectious HIV-like particles

Also Published As

Publication number Publication date
CA2312943C (en) 2009-02-24
AU1657799A (en) 1999-07-05
BR9813626A (pt) 2002-07-23
EP1038001B1 (en) 2006-03-01
PT1038001E (pt) 2006-07-31
DK1038001T3 (da) 2006-07-10
US6121021A (en) 2000-09-19
US6572863B1 (en) 2003-06-03
WO1999031250A3 (en) 1999-08-19
DE69833686T2 (de) 2006-11-30
EP1038001B8 (en) 2006-09-13
AU749174B2 (en) 2002-06-20
JP2004509601A (ja) 2004-04-02
DE69833686D1 (de) 2006-04-27
CA2312943A1 (en) 1999-06-24
ES2262250T3 (es) 2006-11-16
WO1999031250A2 (en) 1999-06-24
EP1038001A2 (en) 2000-09-27

Similar Documents

Publication Publication Date Title
ATE318909T1 (de) Konstitutive expression von nicht-infektiöser hiv-ähnlicher teilchen
PL332876A1 (en) Lentoviral vectors
NO983102L (no) Uttrykk og forsterkning av sekvenselementer (EASE) for eukaryote ekspresjonssystemer
ATE349540T1 (de) Expression der bazillus thuringiensis cry- proteine in pflanzen-plastiden
AU2002257420A1 (en) A system for inducible expression in eukaryotic cells
DK0747485T3 (da) Fremstilling af proteiner ved anvendelse af homolog rekombination
DE69637147D1 (de) Transportproteine und deren verwendungen
BG60107B2 (bg) Метод за получаване на еукариотен полипептид
TR199801933A2 (xx) Biyolojik olarak tolare edilebilen d���k molek�ler polietileniminler.
DK1702979T3 (da) Improved keratinocyte culture and uses thereof
AU634289B2 (en) A multifunctional rna having self-processing activity, the preparation thereof and the use thereof
AU5539898A (en) Nucleic acid construct for the cell cycle regulated expression of structural genes
DK1025245T3 (da) Hurtig etablering af stabile pattedyrscelelinjer, der producerer höje koncentrationer af rekombinante proteiner
AU2520595A (en) Virosome-mediated intracellular delivery of therapeutic agents
DK0843731T3 (da) Adenovirusvektorer til genterapi
DK203588A (da) Fremgangsmaade til fremstilling af proteiner
EA199900144A1 (ru) Способ индуцирования вирусной устойчивости в растении
DE3577994D1 (de) Vergroessernde virale dna-segmente.
EP0336383A3 (en) Novel recombinant human lymphotoxin
DK176387A (da) Fremgangsmaade til frembringelse af et funktionelt polypeptid i en eukaryot vaertscelle ved anvendelse af en rekombinant dna udtrykkelsesvektor omfattende en bk virusforstaerker
WO2001083822A3 (en) Use of representations of dna for genetic analysis
DK0635061T3 (da) Fremgangsmåde til begrænsning af genetisk manipulerede organismers overlevelse i deres miljø
PT1032418E (pt) Replicoes compactos do virus epstein-barr
NO912099L (no) Ekspresjon av hiv-proteiner i drosophilia-celler.

Legal Events

Date Code Title Description
EEFA Change of the company name
UEP Publication of translation of european patent specification

Ref document number: 1038001

Country of ref document: EP