ATE317397T1 - Transparente flüssigkeit zur verabreichung von verkapselten medikamenten - Google Patents
Transparente flüssigkeit zur verabreichung von verkapselten medikamentenInfo
- Publication number
- ATE317397T1 ATE317397T1 AT95904099T AT95904099T ATE317397T1 AT E317397 T1 ATE317397 T1 AT E317397T1 AT 95904099 T AT95904099 T AT 95904099T AT 95904099 T AT95904099 T AT 95904099T AT E317397 T1 ATE317397 T1 AT E317397T1
- Authority
- AT
- Austria
- Prior art keywords
- pct
- date
- compositions
- sec
- administration
- Prior art date
Links
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 239000007788 liquid Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 5
- 239000013543 active substance Substances 0.000 abstract 3
- 241001465754 Metazoa Species 0.000 abstract 2
- 239000008346 aqueous phase Substances 0.000 abstract 2
- 239000002775 capsule Substances 0.000 abstract 2
- 108010010803 Gelatin Proteins 0.000 abstract 1
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- 229920002472 Starch Polymers 0.000 abstract 1
- 229920000159 gelatin Polymers 0.000 abstract 1
- 239000008273 gelatin Substances 0.000 abstract 1
- 235000019322 gelatine Nutrition 0.000 abstract 1
- 235000011852 gelatine desserts Nutrition 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000012071 phase Substances 0.000 abstract 1
- 239000004014 plasticizer Substances 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- 235000019698 starch Nutrition 0.000 abstract 1
- 239000008107 starch Substances 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/23—Calcitonins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/095—Oxytocins; Vasopressins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
- A61K38/363—Fibrinogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2984—Microcapsule with fluid core [includes liposome]
- Y10T428/2985—Solid-walled microcapsule from synthetic polymer
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Dispersion Chemistry (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15384693A | 1993-11-17 | 1993-11-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE317397T1 true ATE317397T1 (de) | 2006-02-15 |
Family
ID=22548991
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95904099T ATE317397T1 (de) | 1993-11-17 | 1994-11-16 | Transparente flüssigkeit zur verabreichung von verkapselten medikamenten |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5707648A (de) |
| EP (1) | EP0736041B1 (de) |
| JP (3) | JPH09510182A (de) |
| AT (1) | ATE317397T1 (de) |
| AU (1) | AU692506B2 (de) |
| CA (1) | CA2176927C (de) |
| DE (1) | DE69434626D1 (de) |
| WO (1) | WO1995014037A1 (de) |
Families Citing this family (112)
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|---|---|---|---|---|
| US6352707B1 (en) | 1992-02-24 | 2002-03-05 | Anton-Lewis Usala | Transplant encapsulation in a hydrogel matrix to obscure immune recognition |
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| GB9412394D0 (en) * | 1994-06-21 | 1994-08-10 | Danbiosyst Uk | Colonic drug delivery composition |
| GB2318056B (en) * | 1995-08-08 | 1999-05-26 | Danbiosyst Uk | Composition for enhanced uptake of polar drugs from the colon |
| GB9516268D0 (en) | 1995-08-08 | 1995-10-11 | Danbiosyst Uk | Compositiion for enhanced uptake of polar drugs from the colon |
| AUPN801296A0 (en) * | 1996-02-12 | 1996-03-07 | Csl Limited | Stabilised growth hormone formulation and method of preparation thereof |
| ZA9711731B (en) | 1996-12-31 | 1998-07-01 | Monsanto Co | Aqueous glycerol formulations of somatotropin |
| ZA9711733B (en) * | 1996-12-31 | 1998-07-01 | Monsanto Co | Method for solubilization and naturation of somatotropins |
| FR2761889B1 (fr) * | 1997-04-11 | 1999-12-31 | Oreal | Patch pharmaceutique, cosmetique ou dermo-pharmaceutique pour la delivrance de plusieurs composes actifs de nature differente |
| DE69834038D1 (de) | 1997-07-01 | 2006-05-18 | Isis Pharmaceutical Inc | Zusammensetzungen und verfahren zur verabreichung von oligonukleotiden über die speiseröhre |
| US20030133974A1 (en) * | 1997-07-01 | 2003-07-17 | Curatolo William John | Encapsulated solution dosage forms of sertraline |
| US7153845B2 (en) * | 1998-08-25 | 2006-12-26 | Columbia Laboratories, Inc. | Bioadhesive progressive hydration tablets |
| US8765177B2 (en) * | 1997-09-12 | 2014-07-01 | Columbia Laboratories, Inc. | Bioadhesive progressive hydration tablets |
| EP1059941B1 (de) * | 1998-03-05 | 2004-05-26 | Phares Pharmaceutical Research N.V. | Arzneimittel und deren verwendung |
| EP1469009A2 (de) | 1998-05-21 | 2004-10-20 | Isis Parmaceuticals, Inc. | Zusammensetzungen und Verfahren für nicht-parenterale Verabreichung von Oligonukleotiden |
| JP2002515514A (ja) | 1998-05-21 | 2002-05-28 | アイシス・ファーマシューティカルス・インコーポレーテッド | オリゴヌクレオチドの局所送逹のための組成物及び方法 |
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| JP2000237284A (ja) * | 1999-02-17 | 2000-09-05 | Shionogi Qualicaps Kk | 硬質カプセル製剤 |
| US8119159B2 (en) * | 1999-02-22 | 2012-02-21 | Merrion Research Iii Limited | Solid oral dosage form containing an enhancer |
| US20070148228A1 (en) * | 1999-02-22 | 2007-06-28 | Merrion Research I Limited | Solid oral dosage form containing an enhancer |
| US7658938B2 (en) | 1999-02-22 | 2010-02-09 | Merrion Reasearch III Limited | Solid oral dosage form containing an enhancer |
| US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
| US6761903B2 (en) | 1999-06-30 | 2004-07-13 | Lipocine, Inc. | Clear oil-containing pharmaceutical compositions containing a therapeutic agent |
| US6267985B1 (en) | 1999-06-30 | 2001-07-31 | Lipocine Inc. | Clear oil-containing pharmaceutical compositions |
| DE19913692A1 (de) * | 1999-03-25 | 2000-09-28 | Basf Ag | Mechanisch stabile pharmazeutische Darreichungsformen, enthaltend flüssige oder halbfeste oberflächenaktive Substanzen |
| US6228392B1 (en) * | 1999-04-29 | 2001-05-08 | Gene Tools, Llc | Osmotic delivery composition, solution, and method |
| US7169889B1 (en) | 1999-06-19 | 2007-01-30 | Biocon Limited | Insulin prodrugs hydrolyzable in vivo to yield peglylated insulin |
| US20030236236A1 (en) * | 1999-06-30 | 2003-12-25 | Feng-Jing Chen | Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs |
| US6982281B1 (en) * | 2000-11-17 | 2006-01-03 | Lipocine Inc | Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs |
| US6309663B1 (en) | 1999-08-17 | 2001-10-30 | Lipocine Inc. | Triglyceride-free compositions and methods for enhanced absorption of hydrophilic therapeutic agents |
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| US7732404B2 (en) * | 1999-12-30 | 2010-06-08 | Dexcel Ltd | Pro-nanodispersion for the delivery of cyclosporin |
| DE10026698A1 (de) * | 2000-05-30 | 2001-12-06 | Basf Ag | Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung |
| DE10026699A1 (de) * | 2000-05-30 | 2001-12-06 | Basf Ag | Formulierung auf Heparin-, Glycosaminoglycan- oder Heparinoidbasis und Verwendung der Formulierung sowie der Formulierungsgrundlage |
| ATE311192T1 (de) | 2000-05-31 | 2005-12-15 | Encelle Inc | Verfahren zur behandlung von chronischen geschwüren |
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| JP4748923B2 (ja) * | 2000-12-27 | 2011-08-17 | アレス トレーディング ソシエテ アノニム | 低温微粉砕による脂質マイクロ粒子 |
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| US6913903B2 (en) * | 2001-09-07 | 2005-07-05 | Nobex Corporation | Methods of synthesizing insulin polypeptide-oligomer conjugates, and proinsulin polypeptide-oligomer conjugates and methods of synthesizing same |
| US7196059B2 (en) * | 2001-09-07 | 2007-03-27 | Biocon Limited | Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith |
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| US20120148675A1 (en) | 2010-12-10 | 2012-06-14 | Basawaraj Chickmath | Testosterone undecanoate compositions |
| CA2819234A1 (en) | 2011-01-07 | 2012-07-12 | Merrion Research Iii Limited | Pharmaceutical compositions of iron for oral administration |
| KR102196009B1 (ko) | 2011-10-25 | 2021-01-04 | 프로테나 바이오사이언시즈 리미티드 | 항체 제형 및 방법 |
| JP2014532713A (ja) | 2011-11-02 | 2014-12-08 | ハルシオン,インコーポレイテッド | 創傷処置の方法及び組成物 |
| US9668474B2 (en) * | 2012-02-10 | 2017-06-06 | Stepan Company | Structured surfactant suspending systems |
| TWI523863B (zh) | 2012-11-01 | 2016-03-01 | 艾普森藥品公司 | 體抑素-多巴胺嵌合體類似物 |
| HK1213486A1 (zh) | 2012-11-01 | 2016-07-08 | Ipsen Pharma S.A.S. | 促生长素抑制素类似物及其二聚体 |
| WO2016033549A2 (en) | 2014-08-28 | 2016-03-03 | Lipocine Inc. | (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE |
| WO2016033556A1 (en) | 2014-08-28 | 2016-03-03 | Lipocine Inc. | BIOAVAILABLE SOLID STATE (17-β)-HYDROXY-4-ANDROSTEN-3-ONE ESTERS |
| ES2975708T3 (es) | 2015-01-29 | 2024-07-12 | Novo Nordisk As | Comprimidos que comprenden agonista del GLP-1 y recubrimiento entérico |
| US20160361322A1 (en) | 2015-06-15 | 2016-12-15 | Lipocine Inc. | Composition and method for oral delivery of androgen prodrugs |
| EP3544614B1 (de) | 2016-11-28 | 2025-12-31 | Lipocine Inc. | Orale testosteron-undecanoat-therapie |
| JP2021531348A (ja) | 2018-07-20 | 2021-11-18 | リポシン,インク. | 肝臓病 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| DE3237814A1 (de) * | 1982-10-12 | 1984-04-12 | Warner-Lambert Co., 07950 Morris Plains, N.J. | Wasserfreie emulsionen und verwendung derselben |
| EP0190833B1 (de) * | 1985-02-07 | 1991-03-27 | Takeda Chemical Industries, Ltd. | Verfahren zur Herstellung von Mikrokapseln |
| CA1301642C (en) * | 1987-03-30 | 1992-05-26 | Howard Bernard Dawson | Chemical formulations |
| US5026825A (en) * | 1988-09-08 | 1991-06-25 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Intranasal calcitonin formulations |
| US5002771A (en) * | 1989-02-06 | 1991-03-26 | Rorer Pharmaceutical Corp. | Calcitonin suppository formulations |
| US5230185A (en) * | 1990-04-06 | 1993-07-27 | Church & Dwight Co., Inc. | Blasting apparatus and method |
| US5045337A (en) * | 1990-04-19 | 1991-09-03 | The Procter & Gamble Company | Food microemulsion |
| ES2136620T3 (es) * | 1991-04-19 | 1999-12-01 | Lds Technologies Inc | Formulaciones de microemulsiones convertibles. |
| MX9204379A (es) * | 1991-07-26 | 1993-02-01 | Smithkline Beecham Corp | Microemulsiones de agua en aceite auto-emulsificables, estables, farmaceuticamente aceptables. |
| WO1993006921A1 (en) * | 1991-10-04 | 1993-04-15 | Gs Biochem Ab | Particles, method of preparing said particles and uses thereof |
| US5177911A (en) * | 1991-11-15 | 1993-01-12 | Ruemelin Charles R | Abrasive blast cabinet |
| JPH07501022A (ja) * | 1991-11-15 | 1995-02-02 | クラインホーフ・クラウス | スポーク車輪、リムおよびスポーク車輪のためのニップルおよびスポーク車輪のためのリムを造るための方法 |
| US5206219A (en) * | 1991-11-25 | 1993-04-27 | Applied Analytical Industries, Inc. | Oral compositions of proteinaceous medicaments |
| WO1994019001A1 (en) * | 1993-02-17 | 1994-09-01 | Smithkline Beecham Corporation | Microemulsions comprising therapeutic peptides |
| EP0684832A4 (de) * | 1993-02-17 | 1996-09-11 | Smithkline Beecham Corp | Mikroemulsionen enthaltende pharmazeutische zubereitungen. |
| EP0684834A4 (de) * | 1993-02-17 | 1996-09-25 | Smithkline Beecham Corp | Mikroemulsionen, die therapeutische peptide enthalten. |
-
1994
- 1994-11-16 AU AU12917/95A patent/AU692506B2/en not_active Expired
- 1994-11-16 JP JP7514649A patent/JPH09510182A/ja not_active Withdrawn
- 1994-11-16 US US08/406,935 patent/US5707648A/en not_active Expired - Lifetime
- 1994-11-16 DE DE69434626T patent/DE69434626D1/de not_active Expired - Lifetime
- 1994-11-16 CA CA2176927A patent/CA2176927C/en not_active Expired - Lifetime
- 1994-11-16 WO PCT/US1994/013394 patent/WO1995014037A1/en not_active Ceased
- 1994-11-16 EP EP95904099A patent/EP0736041B1/de not_active Expired - Lifetime
- 1994-11-16 AT AT95904099T patent/ATE317397T1/de not_active IP Right Cessation
-
2007
- 2007-11-28 JP JP2007307119A patent/JP5100334B2/ja not_active Expired - Lifetime
-
2012
- 2012-03-16 JP JP2012059920A patent/JP2012149074A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2176927A1 (en) | 1995-05-26 |
| JP2012149074A (ja) | 2012-08-09 |
| CA2176927C (en) | 2010-03-23 |
| EP0736041A1 (de) | 1996-10-09 |
| WO1995014037A1 (en) | 1995-05-26 |
| US5707648A (en) | 1998-01-13 |
| EP0736041A4 (de) | 1997-09-10 |
| JP5100334B2 (ja) | 2012-12-19 |
| JP2008101017A (ja) | 2008-05-01 |
| DE69434626D1 (de) | 2006-04-20 |
| AU692506B2 (en) | 1998-06-11 |
| JPH09510182A (ja) | 1997-10-14 |
| AU1291795A (en) | 1995-06-06 |
| EP0736041B1 (de) | 2006-02-08 |
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