ATE313541T1 - Benzofuran derivate und ihre verwendung als antibakterielle wirkstoffe - Google Patents

Benzofuran derivate und ihre verwendung als antibakterielle wirkstoffe

Info

Publication number
ATE313541T1
ATE313541T1 AT01969459T AT01969459T ATE313541T1 AT E313541 T1 ATE313541 T1 AT E313541T1 AT 01969459 T AT01969459 T AT 01969459T AT 01969459 T AT01969459 T AT 01969459T AT E313541 T1 ATE313541 T1 AT E313541T1
Authority
AT
Austria
Prior art keywords
benzofuran derivatives
antibacterial actives
preparation
pharmaceutical compositions
compounds
Prior art date
Application number
AT01969459T
Other languages
English (en)
Inventor
Kaspar Burri
Dieter Gillessen
Sorana Greiveldinger-Poenaru
Khalid Islam
Original Assignee
Arpida Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arpida Ag filed Critical Arpida Ag
Application granted granted Critical
Publication of ATE313541T1 publication Critical patent/ATE313541T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/86—Benzo [b] furans; Hydrogenated benzo [b] furans with an oxygen atom directly attached in position 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT01969459T 2000-07-29 2001-07-20 Benzofuran derivate und ihre verwendung als antibakterielle wirkstoffe ATE313541T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/EP2000/007357 WO2002010156A1 (en) 2000-07-29 2000-07-29 Benzofuran derivatives and their use as antibacterial agents
PCT/EP2001/008426 WO2002010157A1 (en) 2000-07-29 2001-07-20 Benzofuran derivatives and their use as antibacterial agents

Publications (1)

Publication Number Publication Date
ATE313541T1 true ATE313541T1 (de) 2006-01-15

Family

ID=8164043

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01969459T ATE313541T1 (de) 2000-07-29 2001-07-20 Benzofuran derivate und ihre verwendung als antibakterielle wirkstoffe

Country Status (14)

Country Link
US (1) US7030130B2 (de)
EP (1) EP1307445B1 (de)
JP (1) JP2004505077A (de)
CN (1) CN1317277C (de)
AT (1) ATE313541T1 (de)
AU (1) AU2001289714A1 (de)
CA (1) CA2417401C (de)
DE (1) DE60116106T2 (de)
DK (1) DK1307445T3 (de)
ES (1) ES2250474T3 (de)
MX (1) MXPA03000606A (de)
NO (1) NO325691B1 (de)
TW (1) TWI283674B (de)
WO (2) WO2002010156A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6969730B2 (en) 2001-03-16 2005-11-29 Abbott Laboratories Amines as histamine-3 receptor ligands and their therapeutic applications
EP1370546A2 (de) * 2001-03-16 2003-12-17 Abbott Laboratories Amine als histamin-3 rezeptorliganden und ihre therapeutischen anwendungen
HUP0600114A2 (en) * 2003-07-11 2007-09-28 Arpida Ag Benzofuran derivatives and their use in the treatment of microbal infections
WO2005014586A1 (en) * 2003-08-08 2005-02-17 Arpida Ag Novel process for the preparation of 2h-chromenes
DE10351315A1 (de) * 2003-10-31 2005-06-16 Aventis Pharma Deutschland Gmbh 2-Phenyl-benzofuran-Derivate, Verfahren zur ihrer Herstellung und ihre Verwendung
US7148254B2 (en) 2003-10-31 2006-12-12 Sanofi-Aventis Deutschland Gmbh 2-Phenylbenzofuran derivatives, a process for preparing them, and their use
CN101087779A (zh) * 2005-01-07 2007-12-12 阿皮德公开股份有限公司 选择的苯并呋喃衍生物
CN101115743B (zh) * 2005-02-18 2011-04-13 阿皮德公开股份有限公司 用于制备2h-色烯的新方法
US7737157B2 (en) * 2008-08-29 2010-06-15 Hutchison Medipharma Enterprises Limited Pyrimidine compounds
KR101156666B1 (ko) 2010-09-17 2012-06-15 대한민국(농촌진흥청장) 신규한 항생활성 화합물 및 그 화합물을 포함하는 항생 조성물
CN103288805B (zh) * 2013-03-13 2016-09-14 天津药物研究院有限公司 含有苯并呋喃的嘧啶类化合物及其制备方法和用途
RU2657559C2 (ru) * 2015-12-01 2018-06-14 Общество с ограниченной ответственностью "Квантум Фармасьютикалс" Медицинское применение фармацевтических композиций на основе роданиновых производных бензотиофена, ингибиторов белка клеточного деления FtsZ
US11390614B2 (en) 2017-11-10 2022-07-19 Jiangsu Hengrui Medicine Co., Ltd. Method for preparing benzofuran derivative

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB875562A (en) * 1957-02-21 1961-08-23 Wellcome Found Improvements in and relating to pyrimidine derivatives and the preparation thereof
US4438267A (en) * 1980-11-11 1984-03-20 Daluge Susan M Monoheteroring compounds and their use
ZA833067B (en) * 1982-05-01 1984-12-24 Wellcome Found Antibacterial compounds
DK190983A (da) * 1982-05-01 1983-11-02 Wellcome Found 2,4-diamino-5-(substituerede)pyrimidiner, fremgangsmaade til deres fremstilling og mellemprodukter derfor
EP0866791B1 (de) * 1995-12-04 2002-01-30 Arpida AG, Diaminopyrimidine, diese enthaltende pharmazeutische zusammensetzungen und ihre verwendung als antibakterielle mittel

Also Published As

Publication number Publication date
CN1440404A (zh) 2003-09-03
US20040034047A1 (en) 2004-02-19
CA2417401A1 (en) 2002-02-07
CA2417401C (en) 2009-11-10
CN1317277C (zh) 2007-05-23
NO20030417L (no) 2003-01-27
DE60116106D1 (de) 2006-01-26
DE60116106T2 (de) 2006-06-29
WO2002010156A1 (en) 2002-02-07
EP1307445A1 (de) 2003-05-07
MXPA03000606A (es) 2004-04-02
JP2004505077A (ja) 2004-02-19
WO2002010157A1 (en) 2002-02-07
NO325691B1 (no) 2008-07-07
US7030130B2 (en) 2006-04-18
EP1307445B1 (de) 2005-12-21
TWI283674B (en) 2007-07-11
DK1307445T3 (da) 2006-04-10
ES2250474T3 (es) 2006-04-16
AU2001289714A1 (en) 2002-02-13
NO20030417D0 (no) 2003-01-27

Similar Documents

Publication Publication Date Title
ATE286500T1 (de) 1,2,3,4-tetrahydroisochinolin-derivate
NO20034230L (no) 1,2,3,4-tetrahydroisokinolin-derivater som urotensin II reseptor-antagonister
NO20042844L (no) 4-(piperidyl- og pyrrolidyl-alkyl-ureido)-kinoliner som uprotensin II reseptor-antagonister
MXPA03004780A (es) Nuevas sulfamidas.
NO20051102L (no) Sulfonylamino-eddiksyre-derivater
TR200402704T4 (tr) Yeni fenil-propargileter türevleri
IL155806A0 (en) Novel benzazepines and related heterocyclic derivatives which are useful as orexin receptor antagonists
ECSP045378A (es) Derivados novedosos de diazabiciclononeno
ES2243579T3 (es) Derivados de pirazolopirideno.
DE60035639D1 (de) Hydroxydiphenyletherverbindungen
ATE313541T1 (de) Benzofuran derivate und ihre verwendung als antibakterielle wirkstoffe
ATE383345T1 (de) Quinoxalin-3-on-verdindungen als orexin-rezeptor antagonisten.
WO2002024665A8 (en) Arylalkane-sulfonamides having endothelin-antagonist activity
DE60225155D1 (de) 3-substituierte 6,7-dihydroxytetrahydroisochinolin-derivate zur verwendung als antibkaterielle mittel
MY140724A (en) Novel arylethene-sulfonamides
NO20022971L (no) Butyndiol-derivater
IL172675A0 (en) Benzofuran derivatives and their use in the treatment of microbial infections
ATE251619T1 (de) 1,4-dioxacycloalkan-2-one und 1,4-dioxacycloalken-2-one

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1307445

Country of ref document: EP

REN Ceased due to non-payment of the annual fee