ATE311877T1 - Lp(a)-mindernde mittel und inhibitoren der apoprotein (a) produktion - Google Patents

Lp(a)-mindernde mittel und inhibitoren der apoprotein (a) produktion

Info

Publication number
ATE311877T1
ATE311877T1 AT99905282T AT99905282T ATE311877T1 AT E311877 T1 ATE311877 T1 AT E311877T1 AT 99905282 T AT99905282 T AT 99905282T AT 99905282 T AT99905282 T AT 99905282T AT E311877 T1 ATE311877 T1 AT E311877T1
Authority
AT
Austria
Prior art keywords
production
apoprotein
inhibitors
reducing agents
lower alkylene
Prior art date
Application number
AT99905282T
Other languages
English (en)
Inventor
Akira Yamamoto
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ATE311877T1 publication Critical patent/ATE311877T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT99905282T 1998-02-24 1999-02-23 Lp(a)-mindernde mittel und inhibitoren der apoprotein (a) produktion ATE311877T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP4200498 1998-02-24
PCT/JP1999/000798 WO1999043318A1 (fr) 1998-02-24 1999-02-23 AGENTS DE REDUCTION DU TAUX DE Lp(a) ET INHIBITEURS DE LA PRODUCTION D'APOPROTEINE (a)

Publications (1)

Publication Number Publication Date
ATE311877T1 true ATE311877T1 (de) 2005-12-15

Family

ID=12624057

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99905282T ATE311877T1 (de) 1998-02-24 1999-02-23 Lp(a)-mindernde mittel und inhibitoren der apoprotein (a) produktion

Country Status (7)

Country Link
US (1) US6166036A (de)
EP (1) EP1000620B1 (de)
JP (1) JP3412829B2 (de)
AT (1) ATE311877T1 (de)
DE (1) DE69928749T2 (de)
ES (1) ES2255245T3 (de)
WO (1) WO1999043318A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101943676B1 (ko) 2011-06-28 2019-01-29 메르크 파텐트 게엠베하 금속 착물
EP2768808B1 (de) 2011-10-20 2017-11-15 Merck Patent GmbH Materialien für organische elektrolumineszenzvorrichtungen
WO2015186747A1 (ja) * 2014-06-04 2015-12-10 元夫 通 ４－置換安息香酸誘導体の固体分散体、その製造方法およびそれを含む医薬組成物
WO2017070017A1 (en) * 2015-10-23 2017-04-27 Rush University Medical Center Topical compositions providing pain relief and methods of use thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5231184A (en) * 1987-11-23 1993-07-27 Janssen Pharmaceutica N.V. Pridazinamine derivatives
JP2657324B2 (ja) * 1989-04-19 1997-09-24 大塚製薬株式会社 ヘテロ環を有するフェニルカルボン酸誘導体
JPH04112868A (ja) * 1990-09-03 1992-04-14 Otsuka Pharmaceut Co Ltd 置換ヘテロ環を有するフェニルカルボン酸誘導体
ATE309212T1 (de) * 1992-09-11 2005-11-15 Taiho Pharmaceutical Co Ltd Optisch aktive 1-phenylpyrrolidonderivate

Also Published As

Publication number Publication date
DE69928749D1 (de) 2006-01-12
EP1000620B1 (de) 2005-12-07
DE69928749T2 (de) 2006-06-29
US6166036A (en) 2000-12-26
WO1999043318A1 (fr) 1999-09-02
JP3412829B2 (ja) 2003-06-03
EP1000620A1 (de) 2000-05-17
ES2255245T3 (es) 2006-06-16
EP1000620A4 (de) 2004-03-17

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties