ATE309543T1 - Natürlicher ligand von gpcr chemr23 und dessen verwendung - Google Patents
Natürlicher ligand von gpcr chemr23 und dessen verwendungInfo
- Publication number
- ATE309543T1 ATE309543T1 AT02754857T AT02754857T ATE309543T1 AT E309543 T1 ATE309543 T1 AT E309543T1 AT 02754857 T AT02754857 T AT 02754857T AT 02754857 T AT02754857 T AT 02754857T AT E309543 T1 ATE309543 T1 AT E309543T1
- Authority
- AT
- Austria
- Prior art keywords
- chemr23
- gpcr
- coupled receptor
- protein coupled
- natural ligand
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
- G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Analytical Chemistry (AREA)
- Urology & Nephrology (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Rheumatology (AREA)
- Physics & Mathematics (AREA)
- Wood Science & Technology (AREA)
- Gastroenterology & Hepatology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30385801P | 2001-07-09 | 2001-07-09 | |
| US09/905,253 US20030096299A1 (en) | 2001-07-09 | 2001-07-13 | Natural ligand of G protein coupled receptor ChemR23 and uses thereof |
| PCT/EP2002/007647 WO2003006996A2 (en) | 2001-07-09 | 2002-07-09 | Natural ligand of gpcr chemr23 and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE309543T1 true ATE309543T1 (de) | 2005-11-15 |
Family
ID=26973689
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02754857T ATE309543T1 (de) | 2001-07-09 | 2002-07-09 | Natürlicher ligand von gpcr chemr23 und dessen verwendung |
Country Status (9)
| Country | Link |
|---|---|
| US (5) | US20030096299A1 (de) |
| EP (1) | EP1405083B1 (de) |
| JP (2) | JP4446737B2 (de) |
| AT (1) | ATE309543T1 (de) |
| CA (1) | CA2450587C (de) |
| DE (1) | DE60207254T2 (de) |
| DK (1) | DK1405083T3 (de) |
| ES (1) | ES2252494T3 (de) |
| WO (1) | WO2003006996A2 (de) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7858755B2 (en) * | 2001-07-09 | 2010-12-28 | Euroscreen S.A. | Monoclonal antibodies that bind Chemerin polypeptide |
| US20030096299A1 (en) * | 2001-07-09 | 2003-05-22 | Valerie Wittamer | Natural ligand of G protein coupled receptor ChemR23 and uses thereof |
| US7419658B2 (en) * | 2001-07-09 | 2008-09-02 | Euroscreen S.A. | Isolated ligand of ChemerinR |
| US7470772B2 (en) * | 2001-07-09 | 2008-12-30 | Euroscreen S.A. | Antibody that specifically binds to Chemerin receptor ligand precursor |
| AU2003274076A1 (en) * | 2002-10-31 | 2004-05-25 | Ipf Pharmaceuticals Gmbh | Human chondroosteomodulin (tig2), production, and use for the treatment or diagnosis of bone diseases, cartilage diseases, obesity, inflammatory diseases, and skin diseases |
| US20050037946A1 (en) * | 2003-01-13 | 2005-02-17 | Millennium Pharmaceuticals, Inc. | Methods and compositions for treating cardiovascular disease using 1722, 10280, 59917, 85553, 10653, 9235, 21668, 17794, 2210, 6169, 10102, 21061, 17662, 1468, 12282, 6350, 9035, 1820, 23652, 7301, 8925, 8701, 3533, 9462, 9123, 12788, 17729, 65552, 1261, 21476, 33770, 9380, 2569654, 33556, 53656, 44143, 32612, 10671, 261, 44570, 41922, 2552, 2417, 19319, 43969, 8921, 8993, 955, 32345, 966, 1920, 17318, 1510, 14180, 26005, 554, 16408, 42028, 112091, 13886, 13942, 1673, 54946 or 2419 |
| US8580517B2 (en) * | 2003-02-05 | 2013-11-12 | Washington University In St. Louis | Biosensor and use thereof to identify therapeutic drug molecules and molecules binding orphan receptors |
| US20050202029A1 (en) * | 2003-10-03 | 2005-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Family of cystatin-related chemoattractant proteins |
| JP2008502307A (ja) * | 2003-10-28 | 2008-01-31 | プロテミックス ディスカバリー リミティド | 抗肥満活性及び他の関連用途を有するペプチド |
| WO2005050212A1 (en) * | 2003-11-19 | 2005-06-02 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with g protein-coupled receptor chemr23 (chemr23) |
| US8178077B2 (en) * | 2004-10-19 | 2012-05-15 | Reverse Proteomics Research Institute Co., Ltd. | Drug development target protein and target gene, and method of screening |
| EP1864131B1 (de) * | 2005-03-03 | 2011-09-28 | ChemCom S.A. | Natürlicher ligand des g-protein-gekoppelten rezeptors rcc356 und verwendungen davon |
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| CN103539834B (zh) * | 2012-07-09 | 2016-12-21 | 深圳先进技术研究院 | 趋化素衍生肽及其表达基因和应用 |
| US9708413B2 (en) | 2012-11-22 | 2017-07-18 | Glytech, Inc. | Glycosylated linker, compound containing glycosylated linker moiety and physiologically active substance moiety or salt thereof, and methods for producing said compound or salt thereof |
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| US9144178B2 (en) * | 2013-03-01 | 2015-09-22 | International Business Machines Corporation | Selective clamping of electronics card to coolant-cooled structure |
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| CN110609020B (zh) * | 2019-08-15 | 2021-10-01 | 济南大学 | 基于回文分子信标检测atp的生物传感器及其制备方法和应用 |
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| US5948664A (en) | 1996-02-29 | 1999-09-07 | The Regents Of The University Of California | PI 3-kinase polypeptides |
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| JP2002511259A (ja) | 1998-04-09 | 2002-04-16 | ジェンセット | 5’estおよびコードされるヒトタンパク質 |
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| US20030096299A1 (en) | 2001-07-09 | 2003-05-22 | Valerie Wittamer | Natural ligand of G protein coupled receptor ChemR23 and uses thereof |
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2001
- 2001-07-13 US US09/905,253 patent/US20030096299A1/en not_active Abandoned
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2002
- 2002-07-09 WO PCT/EP2002/007647 patent/WO2003006996A2/en not_active Ceased
- 2002-07-09 DK DK02754857T patent/DK1405083T3/da active
- 2002-07-09 ES ES02754857T patent/ES2252494T3/es not_active Expired - Lifetime
- 2002-07-09 DE DE60207254T patent/DE60207254T2/de not_active Expired - Lifetime
- 2002-07-09 AT AT02754857T patent/ATE309543T1/de active
- 2002-07-09 JP JP2003512713A patent/JP4446737B2/ja not_active Expired - Lifetime
- 2002-07-09 CA CA2450587A patent/CA2450587C/en not_active Expired - Lifetime
- 2002-07-09 EP EP02754857A patent/EP1405083B1/de not_active Expired - Lifetime
- 2002-07-23 US US10/201,187 patent/US20030104478A1/en not_active Abandoned
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- 2006-09-29 US US11/529,867 patent/US7582734B2/en not_active Expired - Lifetime
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Also Published As
| Publication number | Publication date |
|---|---|
| DE60207254T2 (de) | 2006-07-13 |
| US20090047741A1 (en) | 2009-02-19 |
| ES2252494T3 (es) | 2006-05-16 |
| WO2003006996A3 (en) | 2003-12-04 |
| US20090081729A1 (en) | 2009-03-26 |
| JP2005500047A (ja) | 2005-01-06 |
| JP4446737B2 (ja) | 2010-04-07 |
| JP2009148278A (ja) | 2009-07-09 |
| US7582734B2 (en) | 2009-09-01 |
| EP1405083B1 (de) | 2005-11-09 |
| CA2450587C (en) | 2011-03-22 |
| WO2003006996A2 (en) | 2003-01-23 |
| US20030104478A1 (en) | 2003-06-05 |
| CA2450587A1 (en) | 2003-01-23 |
| DE60207254D1 (de) | 2005-12-15 |
| US8003347B2 (en) | 2011-08-23 |
| EP1405083A2 (de) | 2004-04-07 |
| US7666401B2 (en) | 2010-02-23 |
| US20070238862A1 (en) | 2007-10-11 |
| US20030096299A1 (en) | 2003-05-22 |
| DK1405083T3 (da) | 2006-03-20 |
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