ATE309358T1 - Superaktive, wachstumshormone freisetzende hormonanaloge vom schwein - Google Patents

Superaktive, wachstumshormone freisetzende hormonanaloge vom schwein

Info

Publication number
ATE309358T1
ATE309358T1 AT00953666T AT00953666T ATE309358T1 AT E309358 T1 ATE309358 T1 AT E309358T1 AT 00953666 T AT00953666 T AT 00953666T AT 00953666 T AT00953666 T AT 00953666T AT E309358 T1 ATE309358 T1 AT E309358T1
Authority
AT
Austria
Prior art keywords
growth
growth hormone
animal
hormone
superactive
Prior art date
Application number
AT00953666T
Other languages
German (de)
English (en)
Inventor
Robert J Schwartz
Ruxandra Draghia-Akli
Original Assignee
Baylor College Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baylor College Medicine filed Critical Baylor College Medicine
Application granted granted Critical
Publication of ATE309358T1 publication Critical patent/ATE309358T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Feed For Specific Animals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Fodder In General (AREA)
AT00953666T 1999-07-26 2000-07-24 Superaktive, wachstumshormone freisetzende hormonanaloge vom schwein ATE309358T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14562499P 1999-07-26 1999-07-26
PCT/US2000/020127 WO2001006988A2 (en) 1999-07-26 2000-07-24 Super-active porcine growth hormone releasing hormone analog

Publications (1)

Publication Number Publication Date
ATE309358T1 true ATE309358T1 (de) 2005-11-15

Family

ID=22513900

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00953666T ATE309358T1 (de) 1999-07-26 2000-07-24 Superaktive, wachstumshormone freisetzende hormonanaloge vom schwein

Country Status (13)

Country Link
US (3) US6551996B1 (https=)
EP (1) EP1204321B1 (https=)
JP (1) JP4644402B2 (https=)
KR (1) KR20020047096A (https=)
CN (1) CN1635898A (https=)
AT (1) ATE309358T1 (https=)
AU (1) AU772752B2 (https=)
BR (1) BR0012748A (https=)
CA (1) CA2378943C (https=)
DE (1) DE60023906T2 (https=)
MX (1) MXPA02000938A (https=)
PL (1) PL366132A1 (https=)
WO (1) WO2001006988A2 (https=)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040192593A1 (en) * 1999-07-26 2004-09-30 Baylor College Of Medicine Protease resistant ti-growth hormone releasing hormone
US20030074679A1 (en) * 2000-12-12 2003-04-17 Schwartz Robert J. Administration of nucleic acid sequence to female animal to enhance growth in offspring
AR035671A1 (es) * 2000-12-12 2004-06-23 Advisys Inc Administracion de secuencia de acido nucleico a un animal hembra, para aumentar el crecimiento de la descendencia
AU2002324909A1 (en) * 2001-09-07 2003-03-24 Baylor College Of Medicine Linear dna fragments for gene expression
AR037038A1 (es) * 2001-10-26 2004-10-20 Baylor College Medicine Una composicion y metodo para alterar la masa corporal magra y las propiedades oseas en un sujeto
AU2002357143B2 (en) 2001-12-11 2009-07-30 Advisys, Inc. Growth hormone releasing hormone supplementation for treating chronically ill subjects
US7250405B2 (en) * 2002-02-07 2007-07-31 Baylor College Of Medicine Modified pituitary gland development in offspring from expectant mother animals treated with growth hormone releasing hormone therapy
CA2485976A1 (en) * 2002-05-28 2003-12-04 Advisys, Inc. Increased delivery of a nucleic acid construct in vivo by the poly-l-glutamate (plg) system
AU2003249208B2 (en) * 2002-07-16 2010-03-04 Vgx Pharmaceuticals, Llc Codon optimized synthetic plasmids
KR20050071498A (ko) * 2002-09-18 2005-07-07 상트르 오스피딸리에 드 루니버시떼 드 몬트리알 성장 호르몬 방출 호르몬 유사체
CA2513743C (en) * 2003-01-28 2013-06-25 Advisys, Inc. Reducing culling in herd animals growth hormone releasing hormone (ghrh)
CA2575926C (en) * 2003-08-04 2014-02-25 Advisys, Inc. Canine specific growth hormone releasing hormone
US7442673B2 (en) * 2003-08-15 2008-10-28 Crompton Corporation Reaction products of mercaptobenzothiazoles, mercaptothiazolines, and mercaptobenzimidazoles with epoxides as lubricant additives
ATE467417T1 (de) * 2003-12-31 2010-05-15 VGX Pharmaceuticals LLC Reduzierung von arthritis und lahmheit bei personen unter supllement von wachstumshormon freisetzendem hormon (ghrh)
US20090005333A1 (en) * 2004-01-26 2009-01-01 Vgx Pharmaceuticlas, Inc. Reducing culling in herd animals growth hormone releasing hormone (ghrh)
US7846720B2 (en) * 2005-01-26 2010-12-07 Vgx Pharmaceuticals, Inc. Optimized high yield synthetic plasmids
DK2118123T3 (en) 2007-01-31 2016-01-25 Dana Farber Cancer Inst Inc Stabilized p53 peptides and uses thereof
US8592377B2 (en) 2007-03-28 2013-11-26 President And Fellows Of Harvard College Stitched polypeptides
US8226468B2 (en) * 2008-11-13 2012-07-24 Igt Gaming system and method including points of symbol expansion
US20100267635A1 (en) * 2009-04-20 2010-10-21 Theratechonolgies Inc. Use of protease inhibitors and grf molecules in combination therapy
US20100267636A1 (en) * 2009-04-20 2010-10-21 Theratechnologies Inc. Use of cytochrome p450-metabolized drugs and grf molecules in combination therapy
ES2711526T3 (es) 2010-08-13 2019-05-06 Aileron Therapeutics Inc Macrociclos peptidomiméticos
TW201806968A (zh) 2011-10-18 2018-03-01 艾利倫治療公司 擬肽巨環化合物
US8993316B2 (en) 2011-11-16 2015-03-31 Brian P. Hanley Methods and compositions for gene therapy and GHRH therapy
CN102516364B (zh) * 2011-12-26 2013-11-06 吉林农业大学 一种模拟猪生长激素样的活性肽及制备方法与应用
EP2819688A4 (en) 2012-02-15 2015-10-28 Aileron Therapeutics Inc TRIAZOL AND THIOETHER-COUPLED PEPTIDOMIMETIC MACROCYCLES
BR112014020103A2 (pt) 2012-02-15 2018-10-09 Aileron Therapeutics, Inc. macrociclos peptidomiméticos
WO2013190520A2 (en) 2012-06-22 2013-12-27 The General Hospital Corporation Gh-releasing agents in the treatment of vascular stenosis and associated conditions
WO2014071241A1 (en) 2012-11-01 2014-05-08 Aileron Therapeutics, Inc. Disubstituted amino acids and methods of preparation and use thereof
EP3197478A4 (en) 2014-09-24 2018-05-30 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
WO2016154058A1 (en) 2015-03-20 2016-09-29 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
WO2017181277A1 (en) 2016-04-19 2017-10-26 Griffon Pharmaceuticals Inc. Pegylated bioactive peptides and uses thereof
CN112724260B (zh) * 2021-01-15 2021-11-30 安徽中起生物科技有限公司 一种脂质体包封的重组兽用促生长蛋白及其制备方法和应用
CN113582881B (zh) * 2021-07-29 2022-10-11 浙江新码生物医药有限公司 一种非天然氨基酸及其应用、包含其的重组蛋白以及重组蛋白偶联物

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4410512A (en) 1981-12-28 1983-10-18 Beckman Instruments, Inc. Combinations having synergistic pituitary growth hormone releasing activity
US5036045A (en) 1985-09-12 1991-07-30 The University Of Virginia Alumni Patents Foundation Method for increasing growth hormone secretion
US4839344A (en) 1987-06-12 1989-06-13 Eastman Kodak Company Polypeptide compounds having growth hormone releasing activity
USRE33699E (en) 1987-07-09 1991-09-24 International Minerals & Chemical Corp. Growth hormone-releasing factor analogs
US5023322A (en) 1988-08-31 1991-06-11 Mta Kutatas-Es Szervezetelemzo Intezete Analogs of growth hormone releasing factor (GRF) and a method for the preparation thereof
US5084442A (en) 1988-09-06 1992-01-28 Hoffmann-La Roche Inc. Cyclic growth hormone releasing factor analogs and method for the manufacture thereof
US5137872A (en) 1989-09-18 1992-08-11 Pitman-Moore, Inc. Growth hormone-releasing factor analogs
WO1991011522A1 (en) 1990-01-26 1991-08-08 Baylor College Of Medicine MUTATED PROMOTER REGION FROM CHICKEN SKELETAL α-ACTIN GENE
EP0544706A4 (en) 1990-06-29 1993-10-13 Hoffmann-La Roche Inc. Histidine substituted growth hormone releasing factor analogs
US5486505A (en) 1990-07-24 1996-01-23 Polygen Holding Corporation Polypeptide compounds having growth hormone releasing activity
CA2084061A1 (en) 1991-04-09 1992-10-10 Arthur M. Felix Growth hormone releasing factor analogs
US5663146A (en) 1991-08-22 1997-09-02 Administrators Of The Tulane Educational Fund Polypeptide analogues having growth hormone releasing activity
US5298422A (en) 1991-11-06 1994-03-29 Baylor College Of Medicine Myogenic vector systems
AU683121B2 (en) 1993-12-23 1997-10-30 Novo Nordisk A/S Compounds with growth hormone releasing properties
US5792747A (en) 1995-01-24 1998-08-11 The Administrators Of The Tulane Educational Fund Highly potent agonists of growth hormone releasing hormone
EP0820296A4 (en) 1995-04-14 1999-06-30 Univ Tulane ANALOGS OF THE GROWTH HORMONE-RELEASING FACTOR
AU7522896A (en) * 1995-10-27 1997-05-15 Merck & Co., Inc. Wet granulation formulation of a growth hormone secretagogue
US6123964A (en) 1995-10-27 2000-09-26 Merck & Co., Inc. Wet granulation formulation of a growth hormone secretagogue
TW432073B (en) 1995-12-28 2001-05-01 Pfizer Pyrazolopyridine compounds
US6221617B1 (en) * 1996-12-06 2001-04-24 Julie Heinrich Bioassay for growth hormone releasing hormone
US6127341A (en) * 1997-06-20 2000-10-03 Novo Nordisk A/S Compounds with growth hormone releasing properties
EP1005484A1 (en) * 1997-06-20 2000-06-07 Novo Nordisk A/S Compounds with growth hormone releasing properties
AU8589998A (en) * 1997-07-24 1999-02-16 Valentis, Inc. Ghrh expression system and methods of use
ATE511400T1 (de) * 2000-03-03 2011-06-15 Genetronics Inc Nukleinsäure-fomulierungen zur genverabreichung

Also Published As

Publication number Publication date
KR20020047096A (ko) 2002-06-21
US20030148948A1 (en) 2003-08-07
CN1635898A (zh) 2005-07-06
DE60023906T2 (de) 2006-07-20
AU6607800A (en) 2001-02-13
JP2003517294A (ja) 2003-05-27
WO2001006988A3 (en) 2001-08-09
CA2378943A1 (en) 2001-02-01
BR0012748A (pt) 2003-06-10
DE60023906D1 (de) 2005-12-15
WO2001006988A2 (en) 2001-02-01
PL366132A1 (en) 2005-01-24
MXPA02000938A (es) 2004-03-19
US6551996B1 (en) 2003-04-22
EP1204321B1 (en) 2005-11-09
JP4644402B2 (ja) 2011-03-02
AU772752B2 (en) 2004-05-06
US20030129172A1 (en) 2003-07-10
CA2378943C (en) 2012-09-18
EP1204321A4 (en) 2002-11-06
EP1204321A2 (en) 2002-05-15
US7166461B2 (en) 2007-01-23

Similar Documents

Publication Publication Date Title
ATE309358T1 (de) Superaktive, wachstumshormone freisetzende hormonanaloge vom schwein
EP0429586A4 (en) Growth hormone fusion proteins
EP0607297A4 (en) Hormone analogs with multiple ctp extensions.
ATE319827T1 (de) Polypeptid, das die differenzierung unterdrueckt
DE602004012424D1 (de) Homogene herstellungen von il-29
ATE295414T1 (de) Menschliche ctla-8 und verwendung von ctla-8 ähnlichen proteinen
NZ227788A (en) Peptide having growth hormone regulatory effects, and compositions
Uys et al. Changes in digestive enzyme activities of Clarias gariepinus (Pisces: Clariidae) after feeding
FR2678624B1 (https=)
CA2383136A1 (en) Obg3 globular head and uses thereof for decreasing body mass
IL210455A (en) A polypeptide for reducing mammalian signaling 13il, and using a polypeptide to produce a drug for up-regulating gene expression 2ra13-il in mammals
ATE257859T1 (de) Humanes, rekombinantes interferon-beta mit verbesserter löslichkeit
NO954188D0 (no) Modifisert-protein- og -peptid - farmasöytika
ATE464378T1 (de) Verwendung des globulären kopfes von acrp30 zur verstärkung der zunahme von muskelmasse und - differenzierung
DE69831979D1 (de) Gefrorenes lebensmittel
GR3031927T3 (en) Cysteine depleted il-6 muteins
ATE432287T1 (de) Peptidfragmente mit den zelltod verhindernder aktivität
EP0561877A4 (https=)
MXPA02000801A (es) Homologo humano de polinucleotidos, nesp55 de proteina secretora de neuroendocrino bovino y usos el mismo relacionado con la obesidad.
JPS6437298A (en) Production of c-terminal amidated peptide
JPH01131198A (ja) Ｐｔｈ修飾物およびｐｔｈ修飾物含有またはｐｔｈ修飾物からなる治療組成物
EP0191869A4 (en) FISH-CALCITONINE COMBAT AND ITS PRODUCTION AND GENE SYSTEM FOR THIS.
ATE432985T1 (de) Polypeptide mit aktivität der stimulierung von neutrophilen
DE60329838D1 (de) Verwendung von alpha-s2 casein vorläufer-abgeleiteten peptiden
ATE282704T1 (de) Isolierte und gereinigte humane lösliche guanylylcyclase alpha1/beta1 (hsgc alpha1/beta1)

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties