ATE302622T1 - Stabilisierung von implantierbarem bioprothesegewebe - Google Patents

Stabilisierung von implantierbarem bioprothesegewebe

Info

Publication number
ATE302622T1
ATE302622T1 AT01908805T AT01908805T ATE302622T1 AT E302622 T1 ATE302622 T1 AT E302622T1 AT 01908805 T AT01908805 T AT 01908805T AT 01908805 T AT01908805 T AT 01908805T AT E302622 T1 ATE302622 T1 AT E302622T1
Authority
AT
Austria
Prior art keywords
implantable
stabilization
bioprosthetic tissue
tissue
bioprosthesis
Prior art date
Application number
AT01908805T
Other languages
English (en)
Inventor
Narendra Vyavahare
Ivan Alferiev
Robert J Levy
Original Assignee
Philadelphia Children Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philadelphia Children Hospital filed Critical Philadelphia Children Hospital
Application granted granted Critical
Publication of ATE302622T1 publication Critical patent/ATE302622T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/507—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
AT01908805T 2000-02-09 2001-02-02 Stabilisierung von implantierbarem bioprothesegewebe ATE302622T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/501,331 US6391538B1 (en) 2000-02-09 2000-02-09 Stabilization of implantable bioprosthetic tissue
PCT/US2001/003509 WO2001058503A1 (en) 2000-02-09 2001-02-02 Stabilization of implantable bioprosthetic tissue

Publications (1)

Publication Number Publication Date
ATE302622T1 true ATE302622T1 (de) 2005-09-15

Family

ID=23993090

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01908805T ATE302622T1 (de) 2000-02-09 2001-02-02 Stabilisierung von implantierbarem bioprothesegewebe

Country Status (7)

Country Link
US (2) US6391538B1 (de)
EP (1) EP1257305B1 (de)
JP (1) JP4841097B2 (de)
AT (1) ATE302622T1 (de)
CA (1) CA2397263C (de)
DE (1) DE60112897T2 (de)
WO (1) WO2001058503A1 (de)

Families Citing this family (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6254564B1 (en) 1998-09-10 2001-07-03 Percardia, Inc. Left ventricular conduit with blood vessel graft
US6214054B1 (en) * 1998-09-21 2001-04-10 Edwards Lifesciences Corporation Method for fixation of biological tissues having mitigated propensity for post-implantation calcification and thrombosis and bioprosthetic devices prepared thereby
DE10010074B4 (de) 2000-02-28 2005-04-14 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Vorrichtung zur Befestigung und Verankerung von Herzklappenprothesen
DE10010073B4 (de) * 2000-02-28 2005-12-22 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verankerung für implantierbare Herzklappenprothesen
US6468660B2 (en) * 2000-12-29 2002-10-22 St. Jude Medical, Inc. Biocompatible adhesives
FR2828263B1 (fr) 2001-08-03 2007-05-11 Philipp Bonhoeffer Dispositif d'implantation d'un implant et procede d'implantation du dispositif
US7147661B2 (en) * 2001-12-20 2006-12-12 Boston Scientific Santa Rosa Corp. Radially expandable stent
US6878168B2 (en) 2002-01-03 2005-04-12 Edwards Lifesciences Corporation Treatment of bioprosthetic tissues to mitigate post implantation calcification
DE60326541D1 (de) 2002-01-07 2009-04-23 Philadelphia Children Hospital Entgegenwirken bioprothetischer kalzifizierung
US20040148016A1 (en) * 2002-11-07 2004-07-29 Klein Dean A. Biocompatible medical device coatings
US7189259B2 (en) * 2002-11-26 2007-03-13 Clemson University Tissue material and process for bioprosthesis
US7632291B2 (en) 2003-06-13 2009-12-15 Trivascular2, Inc. Inflatable implant
US20050244460A1 (en) * 2004-04-29 2005-11-03 Ivan Alferiev Biodegradable crosslinking strategies using triglycidyl amine (TGA)
DE102005003632A1 (de) 2005-01-20 2006-08-17 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Katheter für die transvaskuläre Implantation von Herzklappenprothesen
CN1903143A (zh) * 2005-07-29 2007-01-31 广东冠昊生物科技有限公司 生物型人工血管及其制备方法
DE102005051849B4 (de) 2005-10-28 2010-01-21 JenaValve Technology Inc., Wilmington Vorrichtung zur Implantation und Befestigung von Herzklappenprothesen
DE102005052628B4 (de) * 2005-11-04 2014-06-05 Jenavalve Technology Inc. Selbstexpandierendes, flexibles Drahtgeflecht mit integrierter Klappenprothese für den transvaskulären Herzklappenersatz und ein System mit einer solchen Vorrichtung und einem Einführkatheter
US20070213813A1 (en) 2005-12-22 2007-09-13 Symetis Sa Stent-valves for valve replacement and associated methods and systems for surgery
FI20060288A0 (fi) * 2006-03-27 2006-03-27 Abr Innova Oy Pinnoitusmenetelmä
EP2077718B2 (de) 2006-10-27 2022-03-09 Edwards Lifesciences Corporation Biologisches gewebe für chirurgische implantation
US8142805B1 (en) 2006-11-06 2012-03-27 Clemson University Research Foundation Implantable devices including fixed tissues
US8753390B2 (en) 2007-03-15 2014-06-17 OrthoSpace Ltd. Methods for implanting a prosthesis in a human shoulder
US9138315B2 (en) 2007-04-13 2015-09-22 Jenavalve Technology Gmbh Medical device for treating a heart valve insufficiency or stenosis
US7896915B2 (en) 2007-04-13 2011-03-01 Jenavalve Technology, Inc. Medical device for treating a heart valve insufficiency
EP3150171A1 (de) 2007-05-15 2017-04-05 JenaValve Technology, Inc. Handgriff zur manipulation einer katheterspitze, kathetersystem und medizinisches einführungssystem zur einführung eines selbstexpandierenden herzklappenstents
US9101691B2 (en) * 2007-06-11 2015-08-11 Edwards Lifesciences Corporation Methods for pre-stressing and capping bioprosthetic tissue
US8858490B2 (en) 2007-07-18 2014-10-14 Silk Road Medical, Inc. Systems and methods for treating a carotid artery
US8357387B2 (en) * 2007-12-21 2013-01-22 Edwards Lifesciences Corporation Capping bioprosthetic tissue to reduce calcification
JP2011513220A (ja) * 2008-02-21 2011-04-28 ヴァトリックス・メディカル・インコーポレーテッド デリバリービヒクルと組み合わせた結合組織安定剤の適用による動脈瘤の処置
US8317858B2 (en) 2008-02-26 2012-11-27 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US9044318B2 (en) 2008-02-26 2015-06-02 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis
US8398704B2 (en) 2008-02-26 2013-03-19 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US8465540B2 (en) 2008-02-26 2013-06-18 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis
ES2903231T3 (es) 2008-02-26 2022-03-31 Jenavalve Tech Inc Stent para el posicionamiento y anclaje de una prótesis valvular en un sitio de implantación en el corazón de un paciente
US9168130B2 (en) * 2008-02-26 2015-10-27 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US20100119605A1 (en) * 2008-11-12 2010-05-13 Isenburg Jason C Compositions for tissue stabilization
US20100292779A1 (en) 2009-05-15 2010-11-18 Helmut Straubinger Device for compressing a stent and a system as well as a method for loading a stent into a medical delivery system
WO2011014563A1 (en) 2009-07-29 2011-02-03 Vatrix Medical, Inc. Tissue stabilization for heart failure
WO2011044455A1 (en) * 2009-10-09 2011-04-14 Vatrix Medical, Inc. In vivo chemical stabilization of vulnerable plaque
FR2951549B1 (fr) 2009-10-15 2013-08-23 Olivier Schussler Procede d'obtention de bioprotheses medicales implantables
US8444624B2 (en) 2009-10-19 2013-05-21 Vatrix Medical, Inc. Vascular medical devices with sealing elements and procedures for the treatment of isolated vessel sections
EP2549957B1 (de) 2010-03-23 2019-01-30 Edwards Lifesciences Corporation Verfahren zur bearbeitung eines scheibenförmigen bioprothese-gewebes
US10856978B2 (en) 2010-05-20 2020-12-08 Jenavalve Technology, Inc. Catheter system
US11278406B2 (en) 2010-05-20 2022-03-22 Jenavalve Technology, Inc. Catheter system for introducing an expandable heart valve stent into the body of a patient, insertion system with a catheter system and medical device for treatment of a heart valve defect
JP2013526388A (ja) 2010-05-25 2013-06-24 イエナバルブ テクノロジー インク 人工心臓弁、及び人工心臓弁とステントを備える経カテーテル搬送体内プロテーゼ
US8906601B2 (en) 2010-06-17 2014-12-09 Edwardss Lifesciences Corporation Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates
US9351829B2 (en) 2010-11-17 2016-05-31 Edwards Lifesciences Corporation Double cross-linkage process to enhance post-implantation bioprosthetic tissue durability
US9289307B2 (en) 2011-10-18 2016-03-22 Ortho-Space Ltd. Prosthetic devices and methods for using same
WO2013056898A1 (en) 2011-10-21 2013-04-25 Jenavalve Technology Inc. Catheter system for introducing an expandable heart valve stent into the body of a patient, insertion system with a catheter system and medical device for treatment of a heart valve defect
DE202013011734U1 (de) 2012-05-16 2014-04-29 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Katheter-Zuführsystem zum Einführen einer expandierbaren Herzklappenprothese sowie medizinische Vorrichtung zum Behandeln eines Herzklappendefekts
US20140017263A1 (en) 2012-06-28 2014-01-16 Clemson University Delivery Agents for Targeted Treatment of Elastin Degradation
US9283241B2 (en) * 2012-07-10 2016-03-15 Clemson University Treatment to render implants resistant to diabetes
US10238771B2 (en) 2012-11-08 2019-03-26 Edwards Lifesciences Corporation Methods for treating bioprosthetic tissue using a nucleophile/electrophile in a catalytic system
JP6563394B2 (ja) 2013-08-30 2019-08-21 イェーナヴァルヴ テクノロジー インコーポレイテッド 人工弁のための径方向に折り畳み自在のフレーム及び当該フレームを製造するための方法
US9795573B2 (en) 2013-09-24 2017-10-24 Clemson University Multi-step connective tissue stabilization method and stabilized tissue formed thereby
US9615922B2 (en) 2013-09-30 2017-04-11 Edwards Lifesciences Corporation Method and apparatus for preparing a contoured biological tissue
US10959839B2 (en) 2013-10-08 2021-03-30 Edwards Lifesciences Corporation Method for directing cellular migration patterns on a biological tissue
WO2016154452A2 (en) 2015-03-24 2016-09-29 Osiris Therapeutics, Inc. Compositions comprising meniscal tissues and uses thereof
CN107530168B (zh) 2015-05-01 2020-06-09 耶拿阀门科技股份有限公司 在心脏瓣膜替换中具有降低的起搏器比例的装置和方法
WO2017046647A1 (en) 2015-09-18 2017-03-23 Ortho-Space Ltd. Intramedullary fixated subacromial spacers
EP3454795B1 (de) 2016-05-13 2023-01-11 JenaValve Technology, Inc. Herzklappenprotheseneinführungssystem zur einführung einer herzklappenprothese mit einführerhülse und ladesystem
JP7094965B2 (ja) 2017-01-27 2022-07-04 イエナバルブ テクノロジー インク 心臓弁模倣
US11045981B2 (en) 2017-01-30 2021-06-29 Ortho-Space Ltd. Processing machine and methods for processing dip-molded articles
CA3062547A1 (en) 2017-05-31 2018-12-06 Edwards Lifesciences Corporation Collagen fibers and articles formed therefrom
CN111491675A (zh) 2018-01-23 2020-08-04 爱德华兹生命科学公司 用于预拉伸可植入生物相容性材料的方法及其生产的材料和装置
KR102271744B1 (ko) * 2018-07-25 2021-07-01 가톨릭대학교 산학협력단 생체 모사형 인공방광 및 이의 제어방법
CA3116158A1 (en) 2018-11-01 2020-05-07 Edwards Lifesciences Corporation Transcatheter pulmonic regenerative valve
WO2023237406A1 (en) * 2022-06-08 2023-12-14 Cortronik GmbH Process for applying a polymer coating to a protein-containing biological material

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4394370A (en) * 1981-09-21 1983-07-19 Jefferies Steven R Bone graft material for osseous defects and method of making same
US4753652A (en) 1984-05-04 1988-06-28 Children's Medical Center Corporation Biomaterial implants which resist calcification
CA1264476A (en) * 1985-05-30 1990-01-16 William J. Schultz Epoxy resin curing agent, process, and composition
JPH01500730A (ja) 1986-08-20 1989-03-16 ザ・チャイルドレンズ・メディカル・センター・コーポレーション 生物学的材料移植片
AT398373B (de) * 1987-12-17 1994-11-25 Immuno Ag Biologisches resorbierbares implantationsmaterial sowie verfahren zur herstellung desselben
JP2592420B2 (ja) * 1988-01-25 1997-03-19 日本合成化学工業株式会社 ポリビニルアルコール系繊維の製造法
JPH069920A (ja) * 1992-06-24 1994-01-18 Kansai Paint Co Ltd 水性塗料用樹脂組成物
US5436291A (en) 1992-07-09 1995-07-25 University Of Michigan, The Board Of . . . Calcification-resistant synthetic biomaterials
JPH0680741A (ja) * 1992-08-28 1994-03-22 Seiren Co Ltd 蛋白質含有合成高分子材料及びその調製方法
JPH07184990A (ja) * 1993-12-28 1995-07-25 Kuraray Co Ltd 医療用高分子材料および医療材料
US5891196A (en) * 1997-04-16 1999-04-06 Baxter International Inc. Method for actively binding heparin to crosslinked biological tissues
US6117979A (en) 1997-08-18 2000-09-12 Medtronic, Inc. Process for making a bioprosthetic device and implants produced therefrom
US6008292A (en) * 1997-12-02 1999-12-28 Baxter International Inc. Method for inhibiting calcification of aldehyde-fixed bioprosthetic materials
KR100509855B1 (ko) * 1999-06-25 2005-08-23 가부시키가이샤 가네카 냄새가 억제되고, 세트성이 개량된 재생 콜라겐 섬유 및그 제조 방법, 및 세트 방법

Also Published As

Publication number Publication date
US6391538B1 (en) 2002-05-21
US6824970B2 (en) 2004-11-30
DE60112897D1 (de) 2005-09-29
US20020172706A1 (en) 2002-11-21
CA2397263A1 (en) 2001-08-16
JP2003522001A (ja) 2003-07-22
EP1257305B1 (de) 2005-08-24
JP4841097B2 (ja) 2011-12-21
CA2397263C (en) 2011-01-25
WO2001058503A1 (en) 2001-08-16
EP1257305A1 (de) 2002-11-20
DE60112897T2 (de) 2006-06-08

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