ATE299719T1 - Bioaktive prothesen aus leitendem material beschichtet mit einem polymer und einer substanz mit immunsuppressiven , antistenosen und antithrombosen eigenschaften - Google Patents

Bioaktive prothesen aus leitendem material beschichtet mit einem polymer und einer substanz mit immunsuppressiven , antistenosen und antithrombosen eigenschaften

Info

Publication number
ATE299719T1
ATE299719T1 AT99972115T AT99972115T ATE299719T1 AT E299719 T1 ATE299719 T1 AT E299719T1 AT 99972115 T AT99972115 T AT 99972115T AT 99972115 T AT99972115 T AT 99972115T AT E299719 T1 ATE299719 T1 AT E299719T1
Authority
AT
Austria
Prior art keywords
antistenosis
antithrombosis
immunosupressive
polymer
substance
Prior art date
Application number
AT99972115T
Other languages
English (en)
Inventor
Moel Alain Le
Natacha Betz
Christophe Bureau
Guy Deniau
Charles Baquey
Gerard Deleris
Werner Haberbosch
Original Assignee
Commissariat Energie Atomique
Inst Nat Sante Rech Med
Kerckhoff Klinik Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat Energie Atomique, Inst Nat Sante Rech Med, Kerckhoff Klinik Gmbh filed Critical Commissariat Energie Atomique
Application granted granted Critical
Publication of ATE299719T1 publication Critical patent/ATE299719T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0005—Use of materials characterised by their function or physical properties
    • A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
    • A61L33/0029—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate using an intermediate layer of polymer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/258—Genetic materials, DNA, RNA, genes, vectors, e.g. plasmids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406—Antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/41—Anti-inflammatory agents, e.g. NSAIDs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/42—Anti-thrombotic agents, anticoagulants, anti-platelet agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/18—Modification of implant surfaces in order to improve biocompatibility, cell growth, fixation of biomolecules, e.g. plasma treatment

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Materials Engineering (AREA)
  • Biomedical Technology (AREA)
  • Surgery (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT99972115T 1998-11-16 1999-11-15 Bioaktive prothesen aus leitendem material beschichtet mit einem polymer und einer substanz mit immunsuppressiven , antistenosen und antithrombosen eigenschaften ATE299719T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9814351A FR2785812B1 (fr) 1998-11-16 1998-11-16 Protheses bioactives, notamment a proprietes immunosuppressives, antistenose et antithrombose, et leur fabrication
PCT/FR1999/002795 WO2000029043A1 (fr) 1998-11-16 1999-11-15 Protheses bioactives a proprietes immunosuppressives, antistenose et antithrombose

Publications (1)

Publication Number Publication Date
ATE299719T1 true ATE299719T1 (de) 2005-08-15

Family

ID=9532761

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99972115T ATE299719T1 (de) 1998-11-16 1999-11-15 Bioaktive prothesen aus leitendem material beschichtet mit einem polymer und einer substanz mit immunsuppressiven , antistenosen und antithrombosen eigenschaften

Country Status (14)

Country Link
US (1) US6517858B1 (de)
EP (1) EP1131113B1 (de)
JP (1) JP4294873B2 (de)
AT (1) ATE299719T1 (de)
AU (1) AU769176B2 (de)
CA (1) CA2349930C (de)
DE (1) DE69926255T2 (de)
DK (1) DK1131113T3 (de)
ES (1) ES2246592T3 (de)
FR (1) FR2785812B1 (de)
IL (2) IL143086A0 (de)
MX (1) MXPA01004898A (de)
PT (1) PT1131113E (de)
WO (1) WO2000029043A1 (de)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7807211B2 (en) 1999-09-03 2010-10-05 Advanced Cardiovascular Systems, Inc. Thermal treatment of an implantable medical device
US20050002986A1 (en) * 2000-05-12 2005-01-06 Robert Falotico Drug/drug delivery systems for the prevention and treatment of vascular disease
US8236048B2 (en) 2000-05-12 2012-08-07 Cordis Corporation Drug/drug delivery systems for the prevention and treatment of vascular disease
US6776796B2 (en) 2000-05-12 2004-08-17 Cordis Corportation Antiinflammatory drug and delivery device
US20070276475A1 (en) 2000-09-29 2007-11-29 Llanos Gerard H Medical Devices, Drug Coatings and Methods for Maintaining the Drug Coatings Thereon
JP5100951B2 (ja) 2000-09-29 2012-12-19 コーディス・コーポレイション 被覆医用器具
FR2821575B1 (fr) * 2001-03-02 2003-10-24 Commissariat Energie Atomique Procede de greffage organique localise sans masque sur des protions conductrices ou semiconductrices de surfaces composites
US20020163504A1 (en) * 2001-03-13 2002-11-07 Pallakoff Matthew G. Hand-held device that supports fast text typing
US7247313B2 (en) * 2001-06-27 2007-07-24 Advanced Cardiovascular Systems, Inc. Polyacrylates coatings for implantable medical devices
FR2829046B1 (fr) * 2001-08-28 2005-01-14 Commissariat Energie Atomique Procede de greffage et de croissance d'un film organique conducteur sur une surface
US8303651B1 (en) 2001-09-07 2012-11-06 Advanced Cardiovascular Systems, Inc. Polymeric coating for reducing the rate of release of a therapeutic substance from a stent
US7153656B2 (en) * 2001-09-11 2006-12-26 Los Alamos National Security, Llc Nucleic acid sequence detection using multiplexed oligonucleotide PCR
US20030208166A1 (en) * 2002-05-06 2003-11-06 Schwartz Anthony H. Implantable device with free-flowing exit and uses thereof
US7655038B2 (en) 2003-02-28 2010-02-02 Biointeractions Ltd. Polymeric network system for medical devices and methods of use
US7736394B2 (en) * 2002-08-22 2010-06-15 Victhom Human Bionics Inc. Actuated prosthesis for amputees
EP1531766B1 (de) 2002-08-22 2012-08-01 Victhom Human Bionics Inc. Betätigbare beinprothese für oberschenkelamputierte
US20050095267A1 (en) * 2002-12-04 2005-05-05 Todd Campbell Nanoparticle-based controlled release polymer coatings for medical implants
FR2851258B1 (fr) * 2003-02-17 2007-03-30 Commissariat Energie Atomique Procede de revetement d'une surface, fabrication d'interconnexion en microelectronique utilisant ce procede, et circuits integres
FR2851181B1 (fr) * 2003-02-17 2006-05-26 Commissariat Energie Atomique Procede de revetement d'une surface
EP1608416B1 (de) * 2003-03-31 2009-01-07 Memry Corporation Medizinprodukte mit arzneimittel-elutions-eigenschaften und herstellungsverfahren dafür
US6923996B2 (en) * 2003-05-06 2005-08-02 Scimed Life Systems, Inc. Processes for producing polymer coatings for release of therapeutic agent
US7279174B2 (en) 2003-05-08 2007-10-09 Advanced Cardiovascular Systems, Inc. Stent coatings comprising hydrophilic additives
US20050118344A1 (en) 2003-12-01 2005-06-02 Pacetti Stephen D. Temperature controlled crimping
US7815689B2 (en) 2003-11-18 2010-10-19 Victhom Human Bionics Inc. Instrumented prosthetic foot
US9114198B2 (en) 2003-11-19 2015-08-25 Advanced Cardiovascular Systems, Inc. Biologically beneficial coatings for implantable devices containing fluorinated polymers and methods for fabricating the same
JP4618997B2 (ja) * 2003-12-09 2011-01-26 テルモ株式会社 ステントおよびその製造方法
US7637959B2 (en) 2004-02-12 2009-12-29 össur hf Systems and methods for adjusting the angle of a prosthetic ankle based on a measured surface angle
US7563780B1 (en) * 2004-06-18 2009-07-21 Advanced Cardiovascular Systems, Inc. Heparin prodrugs and drug delivery stents formed therefrom
FR2873016B1 (fr) 2004-07-15 2006-09-29 Pierre Marcel Bourgogne Protheses vasculaires artificielles delivrant en permanence des produits actifs empechant toute stenose, thrombose, proliferation cellulaire, etc.. d'acces aise permanent pour toute intervention
US20060013853A1 (en) * 2004-07-19 2006-01-19 Richard Robert E Medical devices having conductive substrate and covalently bonded coating layer
US8029563B2 (en) 2004-11-29 2011-10-04 Gore Enterprise Holdings, Inc. Implantable devices with reduced needle puncture site leakage
EP2716307B1 (de) * 2006-06-13 2022-08-03 Alchimedics Arzneimittelelutionsstent mit biologisch abbaubarer, mit elektrogepfropfter grundierung befestigter trennschicht
US9028859B2 (en) 2006-07-07 2015-05-12 Advanced Cardiovascular Systems, Inc. Phase-separated block copolymer coatings for implantable medical devices
US20080042662A1 (en) * 2006-08-16 2008-02-21 George Abraham Method For Detecting Stent Coating Defects
CA2673399C (en) 2007-01-05 2017-08-29 Victhom Human Bionics, Inc. Joint actuation mechanism for a prosthetic and/or orthotic device having a compliant transmission
US8211042B2 (en) * 2007-01-05 2012-07-03 Victom Human Bionics Inc. High torque active mechanism for orthotic and/or prosthetic devices
WO2008086629A1 (en) 2007-01-19 2008-07-24 Victhom Human Bionics Inc. Reactive layer control system for prosthetic and orthotic devices
US10265407B2 (en) 2007-02-15 2019-04-23 Yale University Modular nanodevices for smart adaptable vaccines
WO2008109347A2 (en) * 2007-03-02 2008-09-12 Yale University Methods for ex vivo administration of drugs to grafts using polymeric nanoparticles
JP2010526625A (ja) * 2007-05-15 2010-08-05 カメレオン バイオサーフェセズ リミテッド 医療器具へのポリマー・コーティング
US20090076591A1 (en) * 2007-09-19 2009-03-19 Boston Scientific Scimed, Inc. Stent Design Allowing Extended Release of Drug and/or Enhanced Adhesion of Polymer to OD Surface
US7863387B2 (en) 2007-10-25 2011-01-04 Boston Scientific Scimed, Inc. Dehydrofluorination and surface modification of fluoropolymers for drug delivery applications
US7833266B2 (en) * 2007-11-28 2010-11-16 Boston Scientific Scimed, Inc. Bifurcated stent with drug wells for specific ostial, carina, and side branch treatment
WO2009089324A1 (en) * 2008-01-08 2009-07-16 Yale University Compositions and methods for promoting patency of vascular grafts
US20090198321A1 (en) * 2008-02-01 2009-08-06 Boston Scientific Scimed, Inc. Drug-Coated Medical Devices for Differential Drug Release
CN102036626B (zh) 2008-03-24 2014-07-02 奥瑟Hf公司 经股的假肢系统和用于操作该系统的方法
US7951193B2 (en) * 2008-07-23 2011-05-31 Boston Scientific Scimed, Inc. Drug-eluting stent
US9060884B2 (en) 2011-05-03 2015-06-23 Victhom Human Bionics Inc. Impedance simulating motion controller for orthotic and prosthetic applications
US9532877B2 (en) 2011-11-11 2017-01-03 Springactive, Inc. Robotic device and method of using a parallel mechanism
US10543109B2 (en) 2011-11-11 2020-01-28 Össur Iceland Ehf Prosthetic device and method with compliant linking member and actuating linking member
US9044346B2 (en) 2012-03-29 2015-06-02 össur hf Powered prosthetic hip joint
EP2841098A4 (de) 2012-04-23 2016-03-02 Allertein Therapeutics Llc Nanopartikel zur behandlung von allergien
CN105228559B (zh) 2013-02-26 2018-01-09 奥苏尔公司 具有增强的稳定性和弹性能恢复的假足
WO2014159114A1 (en) 2013-03-14 2014-10-02 össur hf Prosthetic ankle: a method of controlling based on adaptation to speed
CN105188741A (zh) 2013-04-03 2015-12-23 阿勒丁医疗公司 新型纳米颗粒组合物
US9814560B2 (en) 2013-12-05 2017-11-14 W. L. Gore & Associates, Inc. Tapered implantable device and methods for making such devices
EP3128958B1 (de) 2014-04-11 2019-08-07 Össur HF Fussprothese mit abnehmbaren flexiblen elementen
EP3180465B1 (de) * 2014-09-16 2020-04-08 SRI International Bibliotheken von nicht-natürlichen, dihydroisoquinolinon-basierten polymeren zur wirkstoffentdeckung mit hohem durchsatz mittels glasfaser-array scan-technologie
CN105031745B (zh) * 2015-05-08 2018-10-19 上海起励生物技术服务中心 一种用聚合物包裹金属假体的骨科内植入物
US10357385B2 (en) 2015-06-05 2019-07-23 W. L. Gore & Associates, Inc. Low bleed implantable prosthesis with a taper
CN108601863A (zh) 2015-12-11 2018-09-28 国家儿童医院研究所 用于优化的患者特异性组织工程化血管移植物的系统和方法
EP3590343A1 (de) * 2018-07-04 2020-01-08 Centre National de la Recherche Scientifique Biozid-materialien und -vorrichtungen

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3826678A (en) * 1972-06-06 1974-07-30 Atomic Energy Commission Method for preparation of biocompatible and biofunctional materials and product thereof
US4879135A (en) * 1984-07-23 1989-11-07 University Of Medicine And Dentistry Of New Jersey Drug bonded prosthesis and process for producing same
US5344455A (en) * 1992-10-30 1994-09-06 Medtronic, Inc. Graft polymer articles having bioactive surfaces
US6174326B1 (en) 1996-09-25 2001-01-16 Terumo Kabushiki Kaisha Radiopaque, antithrombogenic stent and method for its production
CA2268809A1 (en) 1996-10-15 1998-04-23 Ebara Corporation Biologically active polymer products
US6776792B1 (en) * 1997-04-24 2004-08-17 Advanced Cardiovascular Systems Inc. Coated endovascular stent
US6254634B1 (en) * 1998-06-10 2001-07-03 Surmodics, Inc. Coating compositions
US6248127B1 (en) * 1998-08-21 2001-06-19 Medtronic Ave, Inc. Thromboresistant coated medical device

Also Published As

Publication number Publication date
AU769176B2 (en) 2004-01-15
AU1168100A (en) 2000-06-05
IL143086A (en) 2006-08-20
EP1131113A1 (de) 2001-09-12
MXPA01004898A (es) 2007-08-21
DK1131113T3 (da) 2005-11-14
CA2349930C (fr) 2007-06-26
FR2785812B1 (fr) 2002-11-29
FR2785812A1 (fr) 2000-05-19
DE69926255T2 (de) 2006-04-20
JP2002529203A (ja) 2002-09-10
US6517858B1 (en) 2003-02-11
PT1131113E (pt) 2005-11-30
WO2000029043A1 (fr) 2000-05-25
IL143086A0 (en) 2002-04-21
CA2349930A1 (fr) 2000-05-25
DE69926255D1 (de) 2005-08-25
JP4294873B2 (ja) 2009-07-15
ES2246592T3 (es) 2006-02-16
EP1131113B1 (de) 2005-07-20

Similar Documents

Publication Publication Date Title
ATE299719T1 (de) Bioaktive prothesen aus leitendem material beschichtet mit einem polymer und einer substanz mit immunsuppressiven , antistenosen und antithrombosen eigenschaften
CA2366665A1 (en) Polymer coated stent
WO2004030678A3 (en) Polymer compositions containing bioactive agents and methods for their use
ATE428372T1 (de) Beschichtung von stents zur verhinderung von restenose
WO2005084583A3 (en) Medical devices including metallic films and methods for making same
DE69913198D1 (de) Selbstexpandierende prothese mit biokompatibler beschichtung
BR9710100A (pt) Enxerto tubular com distensor e processo para a fabricação de um enxerto de tubular.
ATE255427T1 (de) Stents mit diamantartiger beschichtung
AU2003272774A8 (en) Multilayer stent
WO1998048852A3 (de) Polymerbeschichtete stents
EP1800700A3 (de) Implantat mit durch Laser hergestellter poröser Oberfläche
ATE219165T1 (de) Film- oder schicht-abscheidung und pulver herstellung
EP1493456A3 (de) Medikamente freisetzende Beschichtung für Stents und deren Herstellung
WO2002074194A3 (en) Stent with medicated multi-layer hydrid polymer coating
WO2007056762A3 (en) Grafts and stent grafts having a radiopaque beading
WO2004047873A3 (en) Carbon dioxide-assisted methods of providing biocompatible intraluminal prostheses
ES2183084T3 (es) Aplicacion de materiales a substratos.
DE60204893D1 (de) Gefässprothese beschichtet mit einem funktionellem dextran-derivate
DE50111797D1 (de) Verwendung von Folien aus Poly-Tri-Fluor-Ethoxypolyphosphazenen zur Umhüllung von medizinischen Vorrichtungen
DE69841041D1 (de) Stent beschichtet mit dna
DE60017757D1 (de) Humanisierte biomaterialien enthaltend monozyten oder makrophagen, ein verfahren zu ihrer herstellung und ihre anwendungen
WO2004085098A3 (en) Metallic nanoparticles as orthopedic biomaterial
WO1998058680A3 (de) Mit fluoralkylgruppen beschichtete stents
WO1997049434A3 (en) Heparinized medical devices containing heparin-binding growth factor conjugates
AU4606199A (en) Superficial implant and surface coating for stents and other implants

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1131113

Country of ref document: EP

REN Ceased due to non-payment of the annual fee