ATE299701T1 - Antibakteriell wirksame hydroxamsäure-derivate - Google Patents

Antibakteriell wirksame hydroxamsäure-derivate

Info

Publication number
ATE299701T1
ATE299701T1 AT00901231T AT00901231T ATE299701T1 AT E299701 T1 ATE299701 T1 AT E299701T1 AT 00901231 T AT00901231 T AT 00901231T AT 00901231 T AT00901231 T AT 00901231T AT E299701 T1 ATE299701 T1 AT E299701T1
Authority
AT
Austria
Prior art keywords
group
acid derivatives
represents hydrogen
hydroxamic acid
alkyl
Prior art date
Application number
AT00901231T
Other languages
English (en)
Inventor
Michael George Hunter
Raymond Paul Beckett
Martin John Clements
Mark Whittaker
Original Assignee
Vernalis Oxford Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vernalis Oxford Ltd filed Critical Vernalis Oxford Ltd
Application granted granted Critical
Publication of ATE299701T1 publication Critical patent/ATE299701T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Indole Compounds (AREA)
AT00901231T 1999-01-29 2000-01-27 Antibakteriell wirksame hydroxamsäure-derivate ATE299701T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9901863.2A GB9901863D0 (en) 1999-01-29 1999-01-29 Antibacterial agents
PCT/GB2000/000233 WO2000044373A1 (en) 1999-01-29 2000-01-27 Antibacterial hydroxamic acid derivatives

Publications (1)

Publication Number Publication Date
ATE299701T1 true ATE299701T1 (de) 2005-08-15

Family

ID=10846641

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00901231T ATE299701T1 (de) 1999-01-29 2000-01-27 Antibakteriell wirksame hydroxamsäure-derivate

Country Status (8)

Country Link
US (1) US6545051B1 (de)
EP (1) EP1146867B1 (de)
JP (1) JP2002535362A (de)
AT (1) ATE299701T1 (de)
AU (1) AU2118900A (de)
DE (1) DE60021347T2 (de)
GB (1) GB9901863D0 (de)
WO (1) WO2000044373A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002541197A (ja) * 1999-04-09 2002-12-03 ブリティッシュ バイオテック ファーマシューティカルズ リミテッド 抗菌剤
GB0208579D0 (en) * 2002-04-13 2002-05-22 British Biotech Pharm Antibacterial agents
WO2004062601A2 (en) 2003-01-08 2004-07-29 Chiron Corporation Antibacterial agents
KR100648133B1 (ko) * 2005-04-25 2006-11-23 일동제약주식회사 펩티드 데포르밀라제 저해제로서 신규의 히드록사믹 산유도체 및 그 제조방법
EP2170814B1 (de) 2007-06-12 2016-08-17 Achaogen, Inc. Antibakterielle mittel
EP2847168A1 (de) 2012-05-10 2015-03-18 Achaogen, Inc. Antibakterielle wirkstoffe
US11653649B2 (en) * 2017-06-29 2023-05-23 Kimberly-Clark Worldwide, Inc. Antimicrobial composition including a dihydroxamic acid and methods of inhibiting microbial growth utilizing the same

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8921326D0 (en) 1989-09-21 1989-11-08 Beecham Group Plc Novel treatment
JPH03157372A (ja) * 1989-11-13 1991-07-05 Yamanouchi Pharmaceut Co Ltd Ｙｌ―０１８６９ｐ物質及びその製造法
EP0689538B1 (de) * 1993-03-16 1998-08-12 British Biotech Pharmaceuticals Limited Hydroxamsaeurederivate als metalloproteinase inhibitoren
GB9320660D0 (en) * 1993-10-07 1993-11-24 British Bio Technology Inhibition of cytokine production
GB9401129D0 (en) * 1994-01-21 1994-03-16 British Bio Technology Hydroxamic acid derivatives as metalloproteinase inhibitors
GB9613547D0 (en) 1996-06-27 1996-08-28 Pharmacia Spa Matrix metalloproteinase inhibitors
IL128337A0 (en) * 1996-09-10 2000-01-31 British Biotech Pharm Cytostatic hydroxamic acid derivatives
GB9803005D0 (en) * 1998-02-12 1998-04-08 British Biotech Pharm Anti-inflammatory agents
GB9804777D0 (en) * 1998-03-07 1998-04-29 British Biotech Pharm Anti-inflammatory agents
IL137774A0 (en) * 1998-03-12 2001-10-31 British Biotech Pharm Cytostatic agents

Also Published As

Publication number Publication date
WO2000044373A1 (en) 2000-08-03
EP1146867A1 (de) 2001-10-24
DE60021347T2 (de) 2006-05-24
DE60021347D1 (de) 2005-08-25
GB9901863D0 (en) 1999-03-17
US6545051B1 (en) 2003-04-08
AU2118900A (en) 2000-08-18
JP2002535362A (ja) 2002-10-22
EP1146867B1 (de) 2005-07-20

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Legal Events

Date Code Title Description
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