ATE298565T1 - N-formyl hydroxylamine derivate als inhibitoren der bakteriellen polypeptid deformylase zur behandlung von mikrobiellen infektionen - Google Patents
N-formyl hydroxylamine derivate als inhibitoren der bakteriellen polypeptid deformylase zur behandlung von mikrobiellen infektionenInfo
- Publication number
- ATE298565T1 ATE298565T1 AT01980753T AT01980753T ATE298565T1 AT E298565 T1 ATE298565 T1 AT E298565T1 AT 01980753 T AT01980753 T AT 01980753T AT 01980753 T AT01980753 T AT 01980753T AT E298565 T1 ATE298565 T1 AT E298565T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- inhibitors
- microbial infections
- bacterial polypeptide
- hydroxylamine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/417—Imidazole-alkylamines, e.g. histamine, phentolamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/14—Radicals substituted by nitrogen atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0028519A GB0028519D0 (en) | 2000-11-23 | 2000-11-23 | Antimicrobial agents |
GB0116864A GB0116864D0 (en) | 2001-07-11 | 2001-07-11 | Antimicrobial agents |
PCT/GB2001/004965 WO2002041886A1 (en) | 2000-11-23 | 2001-11-08 | Ydroxamic acid or n-formyl hydroxylamine derivatives as inhibitors of bakterial polypeptide deformylase for treating microbial infections |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE298565T1 true ATE298565T1 (de) | 2005-07-15 |
Family
ID=26245320
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01980753T ATE298565T1 (de) | 2000-11-23 | 2001-11-08 | N-formyl hydroxylamine derivate als inhibitoren der bakteriellen polypeptid deformylase zur behandlung von mikrobiellen infektionen |
Country Status (6)
Country | Link |
---|---|
US (2) | US7173053B2 (de) |
EP (1) | EP1339400B1 (de) |
AT (1) | ATE298565T1 (de) |
AU (1) | AU2002212541A1 (de) |
DE (1) | DE60111768T2 (de) |
WO (1) | WO2002041886A1 (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE298565T1 (de) * | 2000-11-23 | 2005-07-15 | Vernalis Oxford Ltd | N-formyl hydroxylamine derivate als inhibitoren der bakteriellen polypeptid deformylase zur behandlung von mikrobiellen infektionen |
UY27813A1 (es) * | 2002-05-31 | 2003-12-31 | Smithkline Beecham Corp | Inhibidores de la peptido-desformilasa |
WO2005037272A1 (en) * | 2003-10-22 | 2005-04-28 | Arpida A/S | Benzimidazole derivatives and use thereof as peptide deformylase inhibitors |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5733882A (en) * | 1994-01-17 | 1998-03-31 | Smithkline Beecham Corporation | Retroviral protease inhibitors |
US5665753A (en) * | 1994-03-03 | 1997-09-09 | Smithkline Beecham Corporation | Cytokine inhibiting imidazole substituted hydroxamic acid derivatives |
GB9404046D0 (en) | 1994-03-03 | 1994-04-20 | Smithkline Beecham Corp | Novel compounds |
US5703092A (en) * | 1995-04-18 | 1997-12-30 | The Dupont Merck Pharmaceutical Company | Hydroxamic acid compounds as metalloprotease and TNF inhibitors |
US6340709B1 (en) * | 1996-12-17 | 2002-01-22 | Warner-Lambert Company | Use of matrix metalloproteinase inhibitors for treating neurological disorders and promoting wound healing |
PL194240B1 (pl) | 1998-02-07 | 2007-05-31 | British Biotech Pharm | Zastosowanie pochodnych N-formylohydroksyloaminy i amidowa pochodna N-formylohydroksyloaminy |
GB9810464D0 (en) * | 1998-05-16 | 1998-07-15 | British Biotech Pharm | Hydroxamic acid derivatives |
AU3979200A (en) * | 1999-04-09 | 2000-11-14 | British Biotech Pharmaceuticals Limited | Antimicrobial agents |
ATE298565T1 (de) * | 2000-11-23 | 2005-07-15 | Vernalis Oxford Ltd | N-formyl hydroxylamine derivate als inhibitoren der bakteriellen polypeptid deformylase zur behandlung von mikrobiellen infektionen |
-
2001
- 2001-11-08 AT AT01980753T patent/ATE298565T1/de not_active IP Right Cessation
- 2001-11-08 AU AU2002212541A patent/AU2002212541A1/en not_active Abandoned
- 2001-11-08 US US10/432,252 patent/US7173053B2/en not_active Expired - Fee Related
- 2001-11-08 WO PCT/GB2001/004965 patent/WO2002041886A1/en not_active Application Discontinuation
- 2001-11-08 EP EP01980753A patent/EP1339400B1/de not_active Expired - Lifetime
- 2001-11-08 DE DE60111768T patent/DE60111768T2/de not_active Expired - Fee Related
-
2006
- 2006-09-26 US US11/526,591 patent/US20090069322A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20090069322A1 (en) | 2009-03-12 |
US20040106666A1 (en) | 2004-06-03 |
EP1339400A1 (de) | 2003-09-03 |
US7173053B2 (en) | 2007-02-06 |
DE60111768D1 (de) | 2005-08-04 |
AU2002212541A1 (en) | 2002-06-03 |
DE60111768T2 (de) | 2006-04-27 |
EP1339400B1 (de) | 2005-06-29 |
WO2002041886A1 (en) | 2002-05-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69628466D1 (de) | Zwischenverbindungen zur Herstellung von neunen Pyridoncarbonsäurederivate oder deren Salzen | |
YU55902A (sh) | 3-aminohinazolin-2,4-dioni kao antibakterijska sredstva | |
NZ506679A (en) | HIV inhibiting pyrimidine derivatives | |
MXPA04009497A (es) | Piridinoilpiperidinas como antagonistas de 5-ht1f. | |
TNSN03045A1 (en) | QUINAZOLINES AS MMP-13 INHIBITORS | |
MY133572A (en) | Gyrase inhibitors and uses thereof | |
PE20061305A1 (es) | Compuestos derivados de fenilacetamidas como inhibidores de proteincinasas | |
NZ510369A (en) | Use of heteroaryl substituted N-(indole-2-carbonyl-) amides for treatment of infection | |
NO20081005L (no) | 8-methoxy-9h-isothiazolo[5,4-b]quinoline-3,4-diones and related compounds as anti-infective agents | |
ATE319680T1 (de) | Substituierte 2-benzylamino-2-phenyl- acetamidverbindungen | |
ATE298565T1 (de) | N-formyl hydroxylamine derivate als inhibitoren der bakteriellen polypeptid deformylase zur behandlung von mikrobiellen infektionen | |
DK0625155T3 (da) | Pyrroloimidazolyl- og imidazopyridinyl-substituerede 1H-benzimidazolderivater som aromataseinhibitorer | |
TNSN04121A1 (en) | Acides 3 - (imidazolyl) - 2 - alkoxypropanoiques servant d'inhibiteurs de tafia | |
ATE397609T1 (de) | Corticotropinfreisetzungsfaktor antagonisten | |
DE60021347D1 (de) | Antibakteriell wirksame hydroxamsäure-derivate | |
ATE316953T1 (de) | Stabilisator für hydroxylaminlösungen | |
AP2001002356A0 (en) | Tricyclic analgesics. | |
ATE270295T1 (de) | Benzoxazine zur verwendung in der behandlung parkinsonscher krankheit | |
PE20030538A1 (es) | Derivados de gabusectin, procedimientos para su preparacion y su uso |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |