ATE296575T1 - Herstellungsverfahren für eine medizinische elektrode - Google Patents

Herstellungsverfahren für eine medizinische elektrode

Info

Publication number
ATE296575T1
ATE296575T1 AT01900586T AT01900586T ATE296575T1 AT E296575 T1 ATE296575 T1 AT E296575T1 AT 01900586 T AT01900586 T AT 01900586T AT 01900586 T AT01900586 T AT 01900586T AT E296575 T1 ATE296575 T1 AT E296575T1
Authority
AT
Austria
Prior art keywords
skin
spikes
base member
subject
drug
Prior art date
Application number
AT01900586T
Other languages
English (en)
Inventor
Goran Stemme
Jan Peter Enoksson
Patrick Griss
Pekka Merilainen
Original Assignee
Instrumentarium Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/489,556 external-priority patent/US6622035B1/en
Application filed by Instrumentarium Corp filed Critical Instrumentarium Corp
Application granted granted Critical
Publication of ATE296575T1 publication Critical patent/ATE296575T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/685—Microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/25—Bioelectric electrodes therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/318—Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • A61B5/325—Preparing electrode sites, e.g. by abrasion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0209—Special features of electrodes classified in A61B5/24, A61B5/25, A61B5/283, A61B5/291, A61B5/296, A61B5/053
    • A61B2562/0215—Silver or silver chloride containing
AT01900586T 2000-01-21 2001-01-20 Herstellungsverfahren für eine medizinische elektrode ATE296575T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17742300P 2000-01-21 2000-01-21
US09/489,556 US6622035B1 (en) 2000-01-21 2000-01-21 Electrode for measurement of weak bioelectrical signals
PCT/IB2001/000059 WO2001052731A1 (en) 2000-01-21 2001-01-20 Medical electrode

Publications (1)

Publication Number Publication Date
ATE296575T1 true ATE296575T1 (de) 2005-06-15

Family

ID=26873276

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01900586T ATE296575T1 (de) 2000-01-21 2001-01-20 Herstellungsverfahren für eine medizinische elektrode

Country Status (7)

Country Link
US (1) US20040054393A1 (de)
EP (1) EP1164928B1 (de)
JP (1) JP2003520094A (de)
AT (1) ATE296575T1 (de)
AU (1) AU2542001A (de)
DE (1) DE60111125T2 (de)
WO (1) WO2001052731A1 (de)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6622035B1 (en) 2000-01-21 2003-09-16 Instrumentarium Corp. Electrode for measurement of weak bioelectrical signals
SE0102736D0 (sv) * 2001-08-14 2001-08-14 Patrick Griss Side opened out-of-plane microneedles for microfluidic transdermal interfacing and fabrication process of side opened out-of-plane microneedles
US6785569B2 (en) 2001-09-07 2004-08-31 Orbital Research Dry physiological recording electrode
US8428682B1 (en) 2006-06-16 2013-04-23 Orbital Research Inc. Wet or dry electrode, other sensors, actuators, or markers with a novel adhesive collar
US6782283B2 (en) 2001-09-07 2004-08-24 Robert N. Schmidt Dry penetrating recording device
US7286864B1 (en) 2001-09-07 2007-10-23 Orbital Research, Inc. Dry physiological recording device
US7050847B2 (en) 2002-03-26 2006-05-23 Stig Ollmar Non-invasive in vivo determination of body fluid parameter
US6912417B1 (en) 2002-04-05 2005-06-28 Ichor Medical Systmes, Inc. Method and apparatus for delivery of therapeutic agents
US7630759B2 (en) * 2002-05-20 2009-12-08 Epi-Sci, Llc Method and system for detecting electrophysiological changes in pre-cancerous and cancerous breast tissue and epithelium
CA2444211C (en) 2002-10-11 2013-11-19 Dermal Therapy (Barbados) Inc. Determination of biological conditions using impedance measurements
US6961603B2 (en) * 2003-06-17 2005-11-01 Instrumentarim Corp. Unitary multi-electrode biopotential signal sensor and method for making same
CA2559083C (en) 2004-03-08 2015-06-16 Ichor Medical Systems, Inc. Improved apparatus for electrically mediated delivery of therapeutic agents
EP1602330A1 (de) * 2004-06-04 2005-12-07 Universite Libre De Bruxelles Medizinisches Gerät zur Überwachung des Verhaltens von Gliedemuskeln
US20060047194A1 (en) * 2004-08-31 2006-03-02 Grigorov Ilya L Electrode apparatus and system
US9089691B2 (en) * 2004-12-07 2015-07-28 Cardiac Pacemakers, Inc. Stimulator for auricular branch of vagus nerve
DE102005030859A1 (de) * 2005-07-01 2007-01-04 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Elektrodenanordnung, deren Verwendung sowie Verfahren zu deren Herstellung
DE102005030858A1 (de) * 2005-07-01 2007-01-04 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Elektrodenanordnung, deren Verwendung sowie Verfahren zu deren Herstellung
US9636035B2 (en) 2005-12-14 2017-05-02 Scibase Ab Medical apparatus for determination of biological conditions using impedance measurements
JP5001950B2 (ja) * 2005-12-14 2012-08-15 サイベース、アクチボラグ インピーダンス測定値を用いて生物学的な状態を決定する医療装置
WO2007070004A2 (en) 2005-12-14 2007-06-21 Silex Microsystems Ab Methods for making micro needles and applications thereof
US9610459B2 (en) * 2009-07-24 2017-04-04 Emkinetics, Inc. Cooling systems and methods for conductive coils
US20100168501A1 (en) * 2006-10-02 2010-07-01 Daniel Rogers Burnett Method and apparatus for magnetic induction therapy
US9339641B2 (en) 2006-01-17 2016-05-17 Emkinetics, Inc. Method and apparatus for transdermal stimulation over the palmar and plantar surfaces
US20070167990A1 (en) * 2006-01-17 2007-07-19 Theranova, Llc Method and apparatus for low frequency induction therapy for the treatment of urinary incontinence and overactive bladder
TW200744534A (en) * 2006-06-09 2007-12-16 Univ Nat Chiao Tung Microprobe array structure and manufacturing method thereof
US10786669B2 (en) 2006-10-02 2020-09-29 Emkinetics, Inc. Method and apparatus for transdermal stimulation over the palmar and plantar surfaces
US9005102B2 (en) 2006-10-02 2015-04-14 Emkinetics, Inc. Method and apparatus for electrical stimulation therapy
US11224742B2 (en) 2006-10-02 2022-01-18 Emkinetics, Inc. Methods and devices for performing electrical stimulation to treat various conditions
US7850578B2 (en) * 2006-10-12 2010-12-14 Matt Balaker Exercise device
WO2008043156A1 (en) * 2006-10-13 2008-04-17 Noble House Group Pty. Ltd. Means for sampling animal blood
US8238995B2 (en) * 2006-12-08 2012-08-07 General Electric Company Self-adhering electrodes and methods of making the same
TW200829215A (en) * 2007-01-03 2008-07-16 Univ Nat Chiao Tung Micro probe array and manufacturing method of the trans-print mold thereof
EP2165187B1 (de) 2007-02-01 2018-05-16 LS Biopath, Inc. Gerät und verfahren zum nachweis und zur charakterisierung von anomalem gewebe und anomalen zellen
WO2008095075A1 (en) * 2007-02-01 2008-08-07 Ls Biopath, Inc. Optical system for identification and characterization of abnormal tissue and cells
US7713196B2 (en) * 2007-03-09 2010-05-11 Nellcor Puritan Bennett Llc Method for evaluating skin hydration and fluid compartmentalization
US8755892B2 (en) 2007-05-16 2014-06-17 Cardiac Pacemakers, Inc. Systems for stimulating neural targets
US11672483B2 (en) * 2008-02-04 2023-06-13 University of Pittsburgh—of the Commonwealth System of Higher Education Skin screw electrodes
EP2280645B1 (de) * 2008-05-02 2015-03-18 Covidien LP Hautvorbereitungsvorrichtung und biopotenzialsensor
DE102008048984B4 (de) * 2008-09-25 2012-08-09 Deutsches Zentrum für Luft- und Raumfahrt e.V. Sensor zur Erfassung von elektrischen Biopotentialen sowie medizinischer Apparat mit einem Sensor
US8948838B2 (en) 2009-01-27 2015-02-03 Scibase Ab Switch probe for multiple electrode measurement of impedance
TWI481383B (zh) * 2009-09-25 2015-04-21 Univ Nat Chiao Tung 生醫感測器及其電極結構
AU2010313487A1 (en) 2009-10-26 2012-05-24 Emkinetics, Inc. Method and apparatus for electromagnetic stimulation of nerve, muscle, and body tissues
US8229537B2 (en) 2010-03-17 2012-07-24 General Electric Company Motion artifact rejection microelectrode
WO2011141426A1 (en) 2010-05-10 2011-11-17 Tt Seed S.R.L. Needle device for detecting biosignals through the skin
US8588884B2 (en) * 2010-05-28 2013-11-19 Emkinetics, Inc. Microneedle electrode
WO2012048109A2 (en) * 2010-10-06 2012-04-12 Indiana University Research & Technology Corporation Multi-terminal nanoelectrode array
KR20120046554A (ko) * 2010-11-02 2012-05-10 연세대학교 산학협력단 암 조직 검출용 센서 및 이의 제조방법
CN102353706B (zh) * 2011-06-09 2013-11-06 西安交通大学 一种高深宽比超微钨电极阵列及其制备方法
JP5699818B2 (ja) * 2011-06-09 2015-04-15 株式会社村田製作所 筋電センサ
CN102334989B (zh) * 2011-07-29 2013-03-27 上海交通大学 刺入深度可控的异平面微针阵列脑电干电极
KR101122526B1 (ko) 2011-08-19 2012-03-16 서현배 니들어셈블리의 교체가 편리한 피부미용치료기
US20130150696A1 (en) * 2011-12-12 2013-06-13 Huntington Medical Research Institutes Hybrid multielectrode arrays
US9089268B2 (en) * 2013-03-13 2015-07-28 Advanced Semiconductor Engineering, Inc. Neural sensing device and method for making the same
US9192313B1 (en) 2013-03-14 2015-11-24 Orbital Research Inc. Dry physiological recording device and method of manufacturing
CA2906558A1 (en) * 2013-03-15 2014-09-25 Amit Rajguru Method and apparatus for transdermal stimulation over the palmar and plantar surfaces
US9173583B2 (en) * 2013-03-15 2015-11-03 Advanced Semiconductor Engineering, Inc. Neural sensing device and method for making the same
GB2521342B (en) * 2013-10-17 2016-08-03 Monica Healthcare Ltd Apparatus and method for detecting an abdominal electrophysiological signal
CN104398258B (zh) * 2014-11-03 2016-05-25 中国科学院深圳先进技术研究院 3d微丝电极阵列固定装置及3d微丝电极阵列裁剪方法
JP2016159065A (ja) * 2015-03-05 2016-09-05 ニプロ株式会社 脳波検出用電極
FR3039979B1 (fr) * 2015-08-11 2017-09-01 Bioserenity Procede de mesure d'un parametre electrophysiologique au moyen d'un capteur electrode capacitive de capacite controlee
KR101757203B1 (ko) * 2015-10-08 2017-07-12 (주)와이브레인 생체 신호 감지용 건식 전극 및 이를 제조하는 방법
KR101727149B1 (ko) * 2015-10-22 2017-04-14 (주)와이브레인 생체 신호 감지용 건식 전극 및 이를 제조하는 방법
KR102424007B1 (ko) 2016-03-28 2022-07-26 아이커 메디칼 시스템스 인코포레이티드 치료제를 전달하기 위한 방법 및 장치
US11058337B2 (en) 2017-02-03 2021-07-13 International Business Machines Corporation Flexible silicon nanowire electrode
US11547849B2 (en) 2017-06-07 2023-01-10 Neuronexus Technologies, Inc. Systems and methods for ruggedized penetrating medical electrode arrays
US11109787B2 (en) * 2018-05-21 2021-09-07 Vine Medical LLC Multi-tip probe for obtaining bioelectrical measurements
EP3801243B1 (de) 2018-05-24 2022-04-20 Scibase Ab Impedanzmessvorrichtung
SE544094C2 (en) 2018-11-05 2021-12-21 Scibase Ab Medical device for analyzing epithelial barrier function using electrical impedance spectroscopy
US11744501B2 (en) 2020-05-07 2023-09-05 GE Precision Healthcare LLC Multi-sensor patch
CN113854989B (zh) * 2021-09-27 2024-03-19 武汉大学 用于药物注射的集传感与执行功能于一体的可穿戴器件
EP4257175A1 (de) * 2022-04-04 2023-10-11 Aurimod GmbH Elektrodenarray und elektrode für die periphere nervenstimulation

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1128329A (en) * 1964-12-23 1968-09-25 Nat Res Dev Electrodes for making electrical contact to the living body of a mammal
US4004578A (en) * 1974-09-10 1977-01-25 Salve S.A. Expendable electro-cardiograph electrode
DE3502913C1 (de) * 1985-01-29 1986-07-03 Günter Prof. Dr.rer.nat. 5100 Aachen Rau Messaufnehmer zur nichtinvasiven Erfassung elektrophysiologischer Groessen
US4640290A (en) * 1985-04-25 1987-02-03 Westinghouse Electric Corp. Shielded, self-preparing electrode suitable for electroencephalographic mapping
US4969468A (en) * 1986-06-17 1990-11-13 Alfred E. Mann Foundation For Scientific Research Electrode array for use in connection with a living body and method of manufacture
JPH05173Y2 (de) * 1987-01-20 1993-01-06
US5197471A (en) * 1990-05-24 1993-03-30 Otero Servio T A Dry medical electrode
US5309909A (en) * 1992-05-22 1994-05-10 Physio-Control Corporation Combined skin preparation and monitoring electrode
US5305746A (en) * 1992-09-29 1994-04-26 Aspect Medical Systems, Inc. Disposable, pre-gelled, self-prepping electrode
US5458141A (en) * 1993-08-04 1995-10-17 Quinton Instrument Company Abrasive skin electrode
DE69521459T2 (de) * 1994-02-15 2002-03-28 Kawasaki Steel Co Hochfeste feuerverzinkte stahlplatte mit hervorragenden plattierungseigenschaften und herstellungsverfahren
US5645063A (en) * 1995-06-05 1997-07-08 Quinton Instrument Company Skin electrode having multiple conductive center members
DE19525607A1 (de) * 1995-07-14 1997-01-16 Boehringer Ingelheim Kg Transcorneales Arzneimittelfreigabesystem
ZA975326B (en) * 1996-06-18 1998-01-14 Alza Corp Device and method for enhancing transdermal flux of agents being delivered or sampled.
US6503231B1 (en) * 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
US6662035B2 (en) * 2001-09-13 2003-12-09 Neuropace, Inc. Implantable lead connector assembly for implantable devices and methods of using it

Also Published As

Publication number Publication date
AU2542001A (en) 2001-07-31
DE60111125T2 (de) 2006-05-04
JP2003520094A (ja) 2003-07-02
EP1164928A1 (de) 2002-01-02
US20040054393A1 (en) 2004-03-18
WO2001052731A1 (en) 2001-07-26
DE60111125D1 (de) 2005-07-07
EP1164928B1 (de) 2005-06-01

Similar Documents

Publication Publication Date Title
ATE296575T1 (de) Herstellungsverfahren für eine medizinische elektrode
Henry et al. Microfabricated microneedles: a novel approach to transdermal drug delivery
Henry et al. Micromachined needles for the transdermal delivery of drugs
US6454755B1 (en) Method and apparatus for transdermal delivery of compounds utilizing disruption of the epidermis
JP3696513B2 (ja) 針状体の製造方法
US6503231B1 (en) Microneedle device for transport of molecules across tissue
US8043250B2 (en) High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances
US5879326A (en) Method and apparatus for disruption of the epidermis
ES2308657T3 (es) Microagujas para la administracion de farmacos minimamente invasiva o para el muestreo diagnostico.
ES2235723T3 (es) Dispositivo para raspar la piel.
CA2330207C (en) Microneedle devices and methods of manufacture and use thereof
ATE384549T1 (de) Mikronadel-vorrichtungen und verfahren zur herstellung
US20050261632A1 (en) High-Aspect-Ratio Microdevices and Methods for Transdermal Delivery and Sampling of Active Substances
US20090200262A1 (en) Method for Producing Porous Microneedles and their Use
ATE390167T1 (de) Mikronadelanordnungen
Lee et al. Biocompatible benzocyclobutene (BCB)-based neural implants with micro-fluidic channel
WO2009130926A1 (ja) 経皮投薬方法、ニードル形成体及び経皮投薬装置
US20080051695A1 (en) High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances
CN109152878B (zh) 用于从患者皮肤去除外源颗粒的系统和方法
CN101553275A (zh) 用于活性物质透皮递送和取样的高纵横比微器件和方法
CN112957606A (zh) 皮肤物理促渗剂及其应用
ATE389432T1 (de) Vorrichtung zur transdermalen verabreichung von wirkstoffen
KR101983970B1 (ko) 다단구조 마이크로니들 패치 및 이의 제조방법
CN100402107C (zh) 金属微针阵列芯片及其制备方法和用途
JP2019500194A (ja) 動電学的な経皮及び経粘膜送達の促進装置

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties