ATE293459T1 - Konjugate enthaltend zwei wirkstoffe - Google Patents
Konjugate enthaltend zwei wirkstoffeInfo
- Publication number
- ATE293459T1 ATE293459T1 AT98954603T AT98954603T ATE293459T1 AT E293459 T1 ATE293459 T1 AT E293459T1 AT 98954603 T AT98954603 T AT 98954603T AT 98954603 T AT98954603 T AT 98954603T AT E293459 T1 ATE293459 T1 AT E293459T1
- Authority
- AT
- Austria
- Prior art keywords
- active ingredients
- conjugates containing
- carrier
- linker
- functional group
- Prior art date
Links
- 239000004480 active ingredient Substances 0.000 title 1
- 125000000524 functional group Chemical group 0.000 abstract 2
- 102000009027 Albumins Human genes 0.000 abstract 1
- 108010088751 Albumins Proteins 0.000 abstract 1
- 102000001690 Factor VIII Human genes 0.000 abstract 1
- 108010054218 Factor VIII Proteins 0.000 abstract 1
- 102000008946 Fibrinogen Human genes 0.000 abstract 1
- 108010049003 Fibrinogen Proteins 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 229960000301 factor viii Drugs 0.000 abstract 1
- 229940012952 fibrinogen Drugs 0.000 abstract 1
- 239000003094 microcapsule Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Detergent Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9724143.4A GB9724143D0 (en) | 1997-11-14 | 1997-11-14 | Pharmaceutical conjugate |
| PCT/GB1998/003442 WO1999025383A1 (en) | 1997-11-14 | 1998-11-16 | Conjugates comprising two active agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE293459T1 true ATE293459T1 (de) | 2005-05-15 |
Family
ID=10822123
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98954603T ATE293459T1 (de) | 1997-11-14 | 1998-11-16 | Konjugate enthaltend zwei wirkstoffe |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7001989B2 (https=) |
| EP (1) | EP1047452B1 (https=) |
| JP (1) | JP2001523648A (https=) |
| AT (1) | ATE293459T1 (https=) |
| AU (1) | AU1165899A (https=) |
| DE (1) | DE69829880T2 (https=) |
| ES (1) | ES2238774T3 (https=) |
| GB (1) | GB9724143D0 (https=) |
| WO (1) | WO1999025383A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6933366B2 (en) * | 1996-12-27 | 2005-08-23 | Tripep Ab | Specificity exchangers that redirect antibodies to bacterial adhesion receptors |
| WO1999064072A1 (de) * | 1998-06-10 | 1999-12-16 | Baxter Aktiengesellschaft | Konjugat, bestehend aus einem lektin und einem blutgerinnungsfaktor |
| GB9825105D0 (en) * | 1998-11-16 | 1999-01-13 | Andaris Ltd | Pharamaceutical conjugates |
| GB9827813D0 (en) * | 1998-12-17 | 1999-02-10 | Andaris Ltd | Pharmaceutical conjugates |
| DE19926475A1 (de) * | 1999-06-10 | 2000-12-14 | Ktb Tumorforschungs Gmbh | Träger-Pharmaka-Konjugate |
| AU6389000A (en) * | 1999-07-28 | 2001-02-19 | Valentis, Inc. | Sonoporation of tumors |
| GB0323378D0 (en) * | 2003-10-07 | 2003-11-05 | Univ Leicester | Therapeutic agent |
| JP5230610B2 (ja) | 2006-05-05 | 2013-07-10 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | 二価ｓｍａｃ模倣物およびその使用 |
| GB0623607D0 (en) * | 2006-11-27 | 2007-01-03 | Haemostatix Ltd | Tissue adhesive |
| US20090170195A1 (en) * | 2007-12-28 | 2009-07-02 | Kent State University | Curcumin-hyaluronan compounds |
| CN102112144A (zh) | 2008-05-16 | 2011-06-29 | 拜耳医药保健有限公司 | 靶向性凝固因子及其使用方法 |
| JP5770161B2 (ja) * | 2009-04-06 | 2015-08-26 | ノヴォ ノルディスク アー／エス | 血小板への第ｖｉｉｉ因子タンパク質の標的送達 |
| GB201101740D0 (en) * | 2011-02-01 | 2011-03-16 | Haemostatix Ltd | Therapeutic agents with improved fibrinogen binding |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4970300A (en) * | 1985-02-01 | 1990-11-13 | New York University | Modified factor VIII |
| IL85372A (en) * | 1987-02-12 | 1992-12-01 | Us Health | Penta to nona-peptides with laminin - like activity having an amino acid sequence and anti- metastatic compositions containing them |
| WO1996039128A1 (en) | 1995-06-06 | 1996-12-12 | Hemosphere, Inc. | Protein particles for therapeutic and diagnostic use |
| US5716614A (en) * | 1994-08-05 | 1998-02-10 | Molecular/Structural Biotechnologies, Inc. | Method for delivering active agents to mammalian brains in a complex with eicosapentaenoic acid or docosahexaenoic acid-conjugated polycationic carrier |
| PT796090E (pt) * | 1994-12-16 | 2003-07-31 | Elan Drug Delivery Ltd | Microparticulas reticuladas e sua utilizacao como veiculos terapeuticos |
| ES2232862T3 (es) * | 1996-10-21 | 2005-06-01 | Quadrant Drug Delivery Limited | Sustitutos de plaquetas y procedimientos de conjugacion apropiados para su preparacion. |
-
1997
- 1997-11-14 GB GBGB9724143.4A patent/GB9724143D0/en not_active Ceased
-
1998
- 1998-11-16 AU AU11658/99A patent/AU1165899A/en not_active Abandoned
- 1998-11-16 DE DE69829880T patent/DE69829880T2/de not_active Expired - Lifetime
- 1998-11-16 AT AT98954603T patent/ATE293459T1/de active
- 1998-11-16 WO PCT/GB1998/003442 patent/WO1999025383A1/en not_active Ceased
- 1998-11-16 ES ES98954603T patent/ES2238774T3/es not_active Expired - Lifetime
- 1998-11-16 JP JP2000520816A patent/JP2001523648A/ja active Pending
- 1998-11-16 EP EP98954603A patent/EP1047452B1/en not_active Expired - Lifetime
-
2002
- 2002-11-22 US US10/302,428 patent/US7001989B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU1165899A (en) | 1999-06-07 |
| JP2001523648A (ja) | 2001-11-27 |
| US7001989B2 (en) | 2006-02-21 |
| DE69829880T2 (de) | 2005-09-22 |
| ES2238774T3 (es) | 2005-09-01 |
| WO1999025383A1 (en) | 1999-05-27 |
| GB9724143D0 (en) | 1998-01-14 |
| EP1047452B1 (en) | 2005-04-20 |
| EP1047452A1 (en) | 2000-11-02 |
| DE69829880D1 (de) | 2005-05-25 |
| US20030087826A1 (en) | 2003-05-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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