DE69829880D1 - Konjugate enthaltend zwei wirkstoffe - Google Patents
Konjugate enthaltend zwei wirkstoffeInfo
- Publication number
- DE69829880D1 DE69829880D1 DE69829880T DE69829880T DE69829880D1 DE 69829880 D1 DE69829880 D1 DE 69829880D1 DE 69829880 T DE69829880 T DE 69829880T DE 69829880 T DE69829880 T DE 69829880T DE 69829880 D1 DE69829880 D1 DE 69829880D1
- Authority
- DE
- Germany
- Prior art keywords
- active substances
- carrier
- conjugate contains
- linker
- functional group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Detergent Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9724143.4A GB9724143D0 (en) | 1997-11-14 | 1997-11-14 | Pharmaceutical conjugate |
GB9724143 | 1997-11-14 | ||
PCT/GB1998/003442 WO1999025383A1 (en) | 1997-11-14 | 1998-11-16 | Conjugates comprising two active agents |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69829880D1 true DE69829880D1 (de) | 2005-05-25 |
DE69829880T2 DE69829880T2 (de) | 2005-09-22 |
Family
ID=10822123
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69829880T Expired - Lifetime DE69829880T2 (de) | 1997-11-14 | 1998-11-16 | Konjugate enthaltend zwei wirkstoffe |
Country Status (9)
Country | Link |
---|---|
US (1) | US7001989B2 (de) |
EP (1) | EP1047452B1 (de) |
JP (1) | JP2001523648A (de) |
AT (1) | ATE293459T1 (de) |
AU (1) | AU1165899A (de) |
DE (1) | DE69829880T2 (de) |
ES (1) | ES2238774T3 (de) |
GB (1) | GB9724143D0 (de) |
WO (1) | WO1999025383A1 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6933366B2 (en) * | 1996-12-27 | 2005-08-23 | Tripep Ab | Specificity exchangers that redirect antibodies to bacterial adhesion receptors |
AU4121899A (en) * | 1998-06-10 | 1999-12-30 | Baxter Aktiengesellschaft | Conjugate consisting of a lectin and a blood coagulation factor |
GB9825105D0 (en) * | 1998-11-16 | 1999-01-13 | Andaris Ltd | Pharamaceutical conjugates |
GB9827813D0 (en) * | 1998-12-17 | 1999-02-10 | Andaris Ltd | Pharmaceutical conjugates |
DE19926475A1 (de) * | 1999-06-10 | 2000-12-14 | Ktb Tumorforschungs Gmbh | Träger-Pharmaka-Konjugate |
WO2001008709A1 (en) * | 1999-07-28 | 2001-02-08 | Valentis, Inc. | Sonoporation of tumors |
GB0323378D0 (en) * | 2003-10-07 | 2003-11-05 | Univ Leicester | Therapeutic agent |
NZ572531A (en) | 2006-05-05 | 2011-09-30 | Univ Michigan | Bivalent smac mimetics and the uses thereof |
GB0623607D0 (en) | 2006-11-27 | 2007-01-03 | Haemostatix Ltd | Tissue adhesive |
US20090170195A1 (en) * | 2007-12-28 | 2009-07-02 | Kent State University | Curcumin-hyaluronan compounds |
CA2724630A1 (en) | 2008-05-16 | 2009-11-19 | Bayer Healthcare Llc | Targeted coagulation factors and method of using the same |
CN102482340B (zh) * | 2009-04-06 | 2015-05-13 | 诺沃—诺迪斯克有限公司 | 因子viii蛋白向血小板的靶向递送 |
GB201101740D0 (en) * | 2011-02-01 | 2011-03-16 | Haemostatix Ltd | Therapeutic agents with improved fibrinogen binding |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4970300A (en) * | 1985-02-01 | 1990-11-13 | New York University | Modified factor VIII |
IL85372A (en) * | 1987-02-12 | 1992-12-01 | Us Health | Penta to nona-peptides with laminin - like activity having an amino acid sequence and anti- metastatic compositions containing them |
WO1996039128A1 (en) | 1995-06-06 | 1996-12-12 | Hemosphere, Inc. | Protein particles for therapeutic and diagnostic use |
US5716614A (en) | 1994-08-05 | 1998-02-10 | Molecular/Structural Biotechnologies, Inc. | Method for delivering active agents to mammalian brains in a complex with eicosapentaenoic acid or docosahexaenoic acid-conjugated polycationic carrier |
CN1175208A (zh) * | 1994-12-16 | 1998-03-04 | 安达里斯有限公司 | 交联的微粒及其作为治疗载体的用途 |
EP1028752B1 (de) | 1996-10-21 | 2004-12-15 | Quadrant Drug Delivery Limited | Plättchen-ersatzmittel und geeignetes konjugations-herstellungsverfahren |
-
1997
- 1997-11-14 GB GBGB9724143.4A patent/GB9724143D0/en not_active Ceased
-
1998
- 1998-11-16 JP JP2000520816A patent/JP2001523648A/ja active Pending
- 1998-11-16 AU AU11658/99A patent/AU1165899A/en not_active Abandoned
- 1998-11-16 EP EP98954603A patent/EP1047452B1/de not_active Expired - Lifetime
- 1998-11-16 DE DE69829880T patent/DE69829880T2/de not_active Expired - Lifetime
- 1998-11-16 WO PCT/GB1998/003442 patent/WO1999025383A1/en active IP Right Grant
- 1998-11-16 AT AT98954603T patent/ATE293459T1/de active
- 1998-11-16 ES ES98954603T patent/ES2238774T3/es not_active Expired - Lifetime
-
2002
- 2002-11-22 US US10/302,428 patent/US7001989B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ES2238774T3 (es) | 2005-09-01 |
WO1999025383A1 (en) | 1999-05-27 |
DE69829880T2 (de) | 2005-09-22 |
EP1047452B1 (de) | 2005-04-20 |
GB9724143D0 (en) | 1998-01-14 |
US7001989B2 (en) | 2006-02-21 |
JP2001523648A (ja) | 2001-11-27 |
ATE293459T1 (de) | 2005-05-15 |
EP1047452A1 (de) | 2000-11-02 |
AU1165899A (en) | 1999-06-07 |
US20030087826A1 (en) | 2003-05-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |