ATE29030T1 - Benzothiopyranopyridinone und ihre salze, ihre herstellung und anwendung als arzneimittel und diese enthaltende zubereitungen. - Google Patents
Benzothiopyranopyridinone und ihre salze, ihre herstellung und anwendung als arzneimittel und diese enthaltende zubereitungen.Info
- Publication number
- ATE29030T1 ATE29030T1 AT83401431T AT83401431T ATE29030T1 AT E29030 T1 ATE29030 T1 AT E29030T1 AT 83401431 T AT83401431 T AT 83401431T AT 83401431 T AT83401431 T AT 83401431T AT E29030 T1 ATE29030 T1 AT E29030T1
- Authority
- AT
- Austria
- Prior art keywords
- carbon atoms
- group
- benzothiopyranopyridinones
- salts
- production
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 9
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- FYPPYPNWPSFUMG-UHFFFAOYSA-N 10h-thiochromeno[3,2-b]pyridine 5-oxide Chemical class C1=CC=C2S(=O)C3=CC=CC=C3CC2=N1 FYPPYPNWPSFUMG-UHFFFAOYSA-N 0.000 abstract 1
- -1 2-oxobenzimidazolyl Chemical group 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 230000001090 anti-dopaminergic effect Effects 0.000 abstract 1
- 230000000561 anti-psychotic effect Effects 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000000392 cycloalkenyl group Chemical group 0.000 abstract 1
- 125000000532 dioxanyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/78—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Catalysts (AREA)
- Common Detailed Techniques For Electron Tubes Or Discharge Tubes (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8220433 | 1982-07-14 | ||
| EP83401431A EP0099303B1 (de) | 1982-07-14 | 1983-07-11 | Benzothiopyranopyridinone und ihre Salze, ihre Herstellung und Anwendung als Arzneimittel und diese enthaltende Zubereitungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE29030T1 true ATE29030T1 (de) | 1987-09-15 |
Family
ID=10531672
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT83401431T ATE29030T1 (de) | 1982-07-14 | 1983-07-11 | Benzothiopyranopyridinone und ihre salze, ihre herstellung und anwendung als arzneimittel und diese enthaltende zubereitungen. |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4547507A (de) |
| EP (1) | EP0099303B1 (de) |
| JP (1) | JPS5946286A (de) |
| KR (1) | KR900006755B1 (de) |
| AT (1) | ATE29030T1 (de) |
| AU (1) | AU559672B2 (de) |
| CA (1) | CA1202974A (de) |
| DE (1) | DE3373097D1 (de) |
| DK (1) | DK322383A (de) |
| ES (2) | ES524090A0 (de) |
| FI (1) | FI75162C (de) |
| GB (1) | GB2123419B (de) |
| GR (1) | GR79605B (de) |
| HU (1) | HU188475B (de) |
| IE (1) | IE55315B1 (de) |
| IL (1) | IL69132A (de) |
| NZ (1) | NZ204893A (de) |
| PT (1) | PT77021B (de) |
| ZA (1) | ZA834868B (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4689225A (en) * | 1984-11-02 | 1987-08-25 | Institut Merieux | Vaccine for cytomegalovirus |
| US5198598A (en) * | 1991-07-19 | 1993-03-30 | Henkel Kommanditgesellschaft Auf Aktien | Telomerization process of a conjugated alkadiene with a polyol |
| GB9418326D0 (en) * | 1994-09-12 | 1994-11-02 | Lilly Industries Ltd | Pharmaceutical compounds |
| ES2204932T3 (es) * | 1994-09-12 | 2004-05-01 | Eli Lilly And Company Limited | Moduladores serotonergicos. |
| US5574028A (en) * | 1994-10-31 | 1996-11-12 | Eli Lilly And Company | Method for treating anxiety |
| GB2308362A (en) * | 1995-12-19 | 1997-06-25 | Lilly Industries Ltd | Pharmaceutical indole derivatives |
| AU2003301513A1 (en) * | 2003-08-04 | 2005-02-15 | Valery Khazhmuratovich Zhilov | Cyclic bioisosters of purine system derivatives and a pharmaceutical composition based thereon |
| RU2326870C2 (ru) * | 2003-08-04 | 2008-06-20 | Валерий Хажмуратович ЖИЛОВ | Применение циклических биоизостеров производных пуриновой системы для лечения расстройств, вызванных нарушениями нитрергической и дофаминергической систем |
| EP3375784A1 (de) * | 2017-03-14 | 2018-09-19 | Artax Biopharma Inc. | Aza-dihydro-acridonderivate |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3086972A (en) * | 1960-03-24 | 1963-04-23 | Sandoz Ag | Aza-thiaxanthene derivatives |
| US3236854A (en) * | 1961-09-08 | 1966-02-22 | Rhone Poulenc Sa | Azathioxanthene derivatives |
| CH500215A (de) * | 1967-12-01 | 1970-12-15 | Sandoz Ag | Verfahren zur Herstellung neuer Benzothiopyranopyridinderivate |
| ATE4384T1 (de) * | 1980-03-06 | 1983-08-15 | Roussel-Uclaf | Benzothiopyrano(2,3-c)pyridine und ihre saeureadditions-salze, ihre herstellung, ihre verwendung als arzneimittel und diese verbindungen enthaltende zusammensetzungen. |
-
1983
- 1983-06-30 IL IL69132A patent/IL69132A/xx unknown
- 1983-07-04 ZA ZA834868A patent/ZA834868B/xx unknown
- 1983-07-11 EP EP83401431A patent/EP0099303B1/de not_active Expired
- 1983-07-11 DE DE8383401431T patent/DE3373097D1/de not_active Expired
- 1983-07-11 AT AT83401431T patent/ATE29030T1/de not_active IP Right Cessation
- 1983-07-12 US US06/512,964 patent/US4547507A/en not_active Expired - Fee Related
- 1983-07-12 GR GR71913A patent/GR79605B/el unknown
- 1983-07-12 PT PT77021A patent/PT77021B/pt not_active IP Right Cessation
- 1983-07-13 GB GB08318911A patent/GB2123419B/en not_active Expired
- 1983-07-13 AU AU16781/83A patent/AU559672B2/en not_active Ceased
- 1983-07-13 FI FI832560A patent/FI75162C/fi not_active IP Right Cessation
- 1983-07-13 IE IE1623/83A patent/IE55315B1/en not_active IP Right Cessation
- 1983-07-13 DK DK322383A patent/DK322383A/da not_active Application Discontinuation
- 1983-07-13 HU HU832497A patent/HU188475B/hu not_active IP Right Cessation
- 1983-07-13 ES ES524090A patent/ES524090A0/es active Granted
- 1983-07-13 CA CA000432346A patent/CA1202974A/fr not_active Expired
- 1983-07-13 NZ NZ204893A patent/NZ204893A/en unknown
- 1983-07-14 JP JP58127064A patent/JPS5946286A/ja active Pending
- 1983-07-14 KR KR1019830003209A patent/KR900006755B1/ko not_active Expired
-
1985
- 1985-01-02 ES ES539317A patent/ES8602008A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| IL69132A0 (en) | 1983-10-31 |
| HU188475B (en) | 1986-04-28 |
| AU1678183A (en) | 1984-01-19 |
| KR840005449A (ko) | 1984-11-12 |
| EP0099303B1 (de) | 1987-08-19 |
| US4547507A (en) | 1985-10-15 |
| KR900006755B1 (ko) | 1990-09-20 |
| GB2123419A (en) | 1984-02-01 |
| ES8504811A1 (es) | 1985-04-16 |
| NZ204893A (en) | 1986-07-11 |
| FI75162B (fi) | 1988-01-29 |
| IL69132A (en) | 1986-02-28 |
| AU559672B2 (en) | 1987-03-19 |
| DK322383D0 (da) | 1983-07-13 |
| GB8318911D0 (en) | 1983-08-17 |
| FI75162C (fi) | 1988-05-09 |
| ES539317A0 (es) | 1985-11-01 |
| JPS5946286A (ja) | 1984-03-15 |
| EP0099303A3 (en) | 1984-09-12 |
| GR79605B (de) | 1984-10-31 |
| IE831623L (en) | 1984-01-14 |
| FI832560A0 (fi) | 1983-07-13 |
| IE55315B1 (en) | 1990-08-01 |
| DK322383A (da) | 1984-01-15 |
| PT77021B (fr) | 1986-04-11 |
| ES8602008A1 (es) | 1985-11-01 |
| PT77021A (fr) | 1983-08-01 |
| ES524090A0 (es) | 1985-04-16 |
| ZA834868B (en) | 1984-08-29 |
| GB2123419B (en) | 1985-10-02 |
| EP0099303A2 (de) | 1984-01-25 |
| FI832560L (fi) | 1984-01-15 |
| DE3373097D1 (en) | 1987-09-24 |
| CA1202974A (fr) | 1986-04-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |