ES8504811A1 - Un procedimiento para preparar nuevas benzotiopiridinonas - Google Patents
Un procedimiento para preparar nuevas benzotiopiridinonasInfo
- Publication number
- ES8504811A1 ES8504811A1 ES524090A ES524090A ES8504811A1 ES 8504811 A1 ES8504811 A1 ES 8504811A1 ES 524090 A ES524090 A ES 524090A ES 524090 A ES524090 A ES 524090A ES 8504811 A1 ES8504811 A1 ES 8504811A1
- Authority
- ES
- Spain
- Prior art keywords
- carbon atoms
- group
- benzothiopyranopyridinones
- cycloalkyl
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/78—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Catalysts (AREA)
- Common Detailed Techniques For Electron Tubes Or Discharge Tubes (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
PROCEDIMIENTO PARA PREPARAR NUEVAS BENZOTIOPIRANPIRIDINONAS.CONSISTE EN CONDENSAR UN TIOL DE FORMULA (II) CON UNA 4-PIPERIDONA DE FORMULA (III) O UNA SAL DE LA MISMA, EN PRESENCIA DE UN ACIDO FUERTE COMO POLIFOSFORICO Y CON CALENTAMIENTO DURANTE VARIAS HORAS A VARIOS DIAS, PARA OBTENER LAS BENZOTIOPIRANPIRIDONAS DE FORMULA (I) Y SUS SALES. SIENDO A, B, C Y D IDENTICOS O DIFERENTES Y REPRESENTAN H, UN RADILAL ALQUILO LINEAL O RAMIFICADO DE C 1 A 5, UN RADICAL ALCOXILO LINEAL O RAMIFICADO DE C 1 A 6, UN RADICAL NITRO Y OTROS, O UNO DE LOS GRUPOS A Y B O C Y D, REPRESENTAN CON LOS ATOMOS DE CARBONO A LOS QUE ESTAN UNIDOS, UN CICLO BENCENICO; R, H Y X UN RADICAL ALQUILO DE C 1 A 8.SE UTILIZAN COMO MEDICAMENTOS, POR SUS EFECTOS ANTIDOPAMINERGICOS, ANTIDEPRESIVOS Y ANTISICOTICOS EN EL SISTEMA NERVIOSO AUTONOMO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8220433 | 1982-07-14 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES524090A0 ES524090A0 (es) | 1985-04-16 |
| ES8504811A1 true ES8504811A1 (es) | 1985-04-16 |
Family
ID=10531672
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES524090A Expired ES8504811A1 (es) | 1982-07-14 | 1983-07-13 | Un procedimiento para preparar nuevas benzotiopiridinonas |
| ES539317A Granted ES539317A0 (es) | 1982-07-14 | 1985-01-02 | Un procedimiento para preparar nuevas benzotiopiranpiridinonas |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES539317A Granted ES539317A0 (es) | 1982-07-14 | 1985-01-02 | Un procedimiento para preparar nuevas benzotiopiranpiridinonas |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4547507A (es) |
| EP (1) | EP0099303B1 (es) |
| JP (1) | JPS5946286A (es) |
| KR (1) | KR900006755B1 (es) |
| AT (1) | ATE29030T1 (es) |
| AU (1) | AU559672B2 (es) |
| CA (1) | CA1202974A (es) |
| DE (1) | DE3373097D1 (es) |
| DK (1) | DK322383A (es) |
| ES (2) | ES8504811A1 (es) |
| FI (1) | FI75162C (es) |
| GB (1) | GB2123419B (es) |
| GR (1) | GR79605B (es) |
| HU (1) | HU188475B (es) |
| IE (1) | IE55315B1 (es) |
| IL (1) | IL69132A (es) |
| NZ (1) | NZ204893A (es) |
| PT (1) | PT77021B (es) |
| ZA (1) | ZA834868B (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4689225A (en) * | 1984-11-02 | 1987-08-25 | Institut Merieux | Vaccine for cytomegalovirus |
| US5198598A (en) * | 1991-07-19 | 1993-03-30 | Henkel Kommanditgesellschaft Auf Aktien | Telomerization process of a conjugated alkadiene with a polyol |
| GB9418326D0 (en) * | 1994-09-12 | 1994-11-02 | Lilly Industries Ltd | Pharmaceutical compounds |
| ATE247114T1 (de) * | 1994-09-12 | 2003-08-15 | Lilly Co Eli | Serotonergische modulatoren |
| US5574028A (en) * | 1994-10-31 | 1996-11-12 | Eli Lilly And Company | Method for treating anxiety |
| GB2308362A (en) * | 1995-12-19 | 1997-06-25 | Lilly Industries Ltd | Pharmaceutical indole derivatives |
| US8592421B2 (en) | 2003-08-04 | 2013-11-26 | Valery Khazhmuratovich Zhilov | Cyclic bioisosters of purine system derivatives and a pharmaceutical composition based thereon |
| EP3375784A1 (en) * | 2017-03-14 | 2018-09-19 | Artax Biopharma Inc. | Aza-dihydro-acridone derivatives |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3086972A (en) * | 1960-03-24 | 1963-04-23 | Sandoz Ag | Aza-thiaxanthene derivatives |
| US3236854A (en) * | 1961-09-08 | 1966-02-22 | Rhone Poulenc Sa | Azathioxanthene derivatives |
| CH500215A (de) * | 1967-12-01 | 1970-12-15 | Sandoz Ag | Verfahren zur Herstellung neuer Benzothiopyranopyridinderivate |
| EP0035924B1 (fr) * | 1980-03-06 | 1983-08-03 | Roussel-Uclaf | Nouvelles benzothiopyrano/2,3-c/pyridines et leurs sels avec les acides, leur préparation, leur application à titre de médicaments et les compositions les renfermant |
-
1983
- 1983-06-30 IL IL69132A patent/IL69132A/xx unknown
- 1983-07-04 ZA ZA834868A patent/ZA834868B/xx unknown
- 1983-07-11 AT AT83401431T patent/ATE29030T1/de not_active IP Right Cessation
- 1983-07-11 DE DE8383401431T patent/DE3373097D1/de not_active Expired
- 1983-07-11 EP EP83401431A patent/EP0099303B1/fr not_active Expired
- 1983-07-12 US US06/512,964 patent/US4547507A/en not_active Expired - Fee Related
- 1983-07-12 GR GR71913A patent/GR79605B/el unknown
- 1983-07-12 PT PT77021A patent/PT77021B/pt not_active IP Right Cessation
- 1983-07-13 IE IE1623/83A patent/IE55315B1/en not_active IP Right Cessation
- 1983-07-13 CA CA000432346A patent/CA1202974A/fr not_active Expired
- 1983-07-13 DK DK322383A patent/DK322383A/da not_active Application Discontinuation
- 1983-07-13 NZ NZ204893A patent/NZ204893A/en unknown
- 1983-07-13 AU AU16781/83A patent/AU559672B2/en not_active Ceased
- 1983-07-13 FI FI832560A patent/FI75162C/fi not_active IP Right Cessation
- 1983-07-13 ES ES524090A patent/ES8504811A1/es not_active Expired
- 1983-07-13 GB GB08318911A patent/GB2123419B/en not_active Expired
- 1983-07-13 HU HU832497A patent/HU188475B/hu not_active IP Right Cessation
- 1983-07-14 KR KR1019830003209A patent/KR900006755B1/ko not_active IP Right Cessation
- 1983-07-14 JP JP58127064A patent/JPS5946286A/ja active Pending
-
1985
- 1985-01-02 ES ES539317A patent/ES539317A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| AU1678183A (en) | 1984-01-19 |
| AU559672B2 (en) | 1987-03-19 |
| PT77021B (fr) | 1986-04-11 |
| ES524090A0 (es) | 1985-04-16 |
| EP0099303A3 (en) | 1984-09-12 |
| FI832560A (fi) | 1984-01-15 |
| US4547507A (en) | 1985-10-15 |
| GB8318911D0 (en) | 1983-08-17 |
| HU188475B (en) | 1986-04-28 |
| GB2123419A (en) | 1984-02-01 |
| PT77021A (fr) | 1983-08-01 |
| EP0099303B1 (fr) | 1987-08-19 |
| CA1202974A (fr) | 1986-04-08 |
| GR79605B (es) | 1984-10-31 |
| ES8602008A1 (es) | 1985-11-01 |
| FI75162C (fi) | 1988-05-09 |
| KR900006755B1 (ko) | 1990-09-20 |
| KR840005449A (ko) | 1984-11-12 |
| FI832560A0 (fi) | 1983-07-13 |
| DK322383A (da) | 1984-01-15 |
| ES539317A0 (es) | 1985-11-01 |
| IL69132A0 (en) | 1983-10-31 |
| NZ204893A (en) | 1986-07-11 |
| ZA834868B (en) | 1984-08-29 |
| GB2123419B (en) | 1985-10-02 |
| EP0099303A2 (fr) | 1984-01-25 |
| IE55315B1 (en) | 1990-08-01 |
| DK322383D0 (da) | 1983-07-13 |
| FI75162B (fi) | 1988-01-29 |
| IL69132A (en) | 1986-02-28 |
| DE3373097D1 (en) | 1987-09-24 |
| IE831623L (en) | 1984-01-14 |
| ATE29030T1 (de) | 1987-09-15 |
| JPS5946286A (ja) | 1984-03-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970203 |