ATE286503T1 - (hetero)aryl-sulfonamid derivate, deren herstellung und deren verwenddung als faktor xa inhibitoren - Google Patents

(hetero)aryl-sulfonamid derivate, deren herstellung und deren verwenddung als faktor xa inhibitoren

Info

Publication number
ATE286503T1
ATE286503T1 AT98935200T AT98935200T ATE286503T1 AT E286503 T1 ATE286503 T1 AT E286503T1 AT 98935200 T AT98935200 T AT 98935200T AT 98935200 T AT98935200 T AT 98935200T AT E286503 T1 ATE286503 T1 AT E286503T1
Authority
AT
Austria
Prior art keywords
optionally substituted
heterocyclic ring
preparation
antithrombotic
alkyl
Prior art date
Application number
AT98935200T
Other languages
English (en)
Inventor
John Preston
Andrew Stocker
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE286503T1 publication Critical patent/ATE286503T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT98935200T 1997-07-29 1998-07-23 (hetero)aryl-sulfonamid derivate, deren herstellung und deren verwenddung als faktor xa inhibitoren ATE286503T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9715895.0A GB9715895D0 (en) 1997-07-29 1997-07-29 Heterocyclic compounds
PCT/GB1998/002200 WO1999009027A1 (en) 1997-07-29 1998-07-23 (hetero)aryl-sulfonamide derivatives, their preparation and their use as factor xa inhibitors

Publications (1)

Publication Number Publication Date
ATE286503T1 true ATE286503T1 (de) 2005-01-15

Family

ID=10816579

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98935200T ATE286503T1 (de) 1997-07-29 1998-07-23 (hetero)aryl-sulfonamid derivate, deren herstellung und deren verwenddung als faktor xa inhibitoren

Country Status (10)

Country Link
US (1) US6486154B1 (de)
EP (1) EP1015449B1 (de)
JP (1) JP2001515077A (de)
AT (1) ATE286503T1 (de)
AU (1) AU8454998A (de)
DE (1) DE69828516T2 (de)
ES (1) ES2234133T3 (de)
GB (1) GB9715895D0 (de)
PT (1) PT1015449E (de)
WO (1) WO1999009027A1 (de)

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WO2003000657A1 (fr) 2001-06-20 2003-01-03 Daiichi Pharmaceutical Co., Ltd. Derives de diamine
DE10155075A1 (de) 2001-11-09 2003-05-22 Merck Patent Gmbh Cyclische Sulfonamide
DK1569912T3 (en) 2002-12-03 2015-06-29 Pharmacyclics Inc 2- (2-hydroxybiphenyl-3-yl) -1h-benzoimidazole-5-carboxamidine derivatives as factor VIIa inhibitors.
WO2005019200A2 (en) * 2003-08-14 2005-03-03 Icos Corporation Aryl piperidine derivatives as vla-1 integrin antagonists and uses thereof
TWI396686B (zh) 2004-05-21 2013-05-21 Takeda Pharmaceutical 環狀醯胺衍生物、以及其製品和用法
US7815871B2 (en) 2006-04-18 2010-10-19 Advanced Liquid Logic, Inc. Droplet microactuator system
CN105829296A (zh) 2013-12-18 2016-08-03 巴斯夫欧洲公司 带有亚胺衍生的取代基的唑类化合物

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Also Published As

Publication number Publication date
WO1999009027A1 (en) 1999-02-25
DE69828516D1 (de) 2005-02-10
JP2001515077A (ja) 2001-09-18
EP1015449A1 (de) 2000-07-05
GB9715895D0 (en) 1997-10-01
AU8454998A (en) 1999-03-08
EP1015449B1 (de) 2005-01-05
US6486154B1 (en) 2002-11-26
DE69828516T2 (de) 2006-01-05
ES2234133T3 (es) 2005-06-16
PT1015449E (pt) 2005-04-29

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