ATE285755T1 - Grosse poröse partikel erhältlich durch sprühtrocknung und geeignet zur pulmonalen anwendung - Google Patents
Grosse poröse partikel erhältlich durch sprühtrocknung und geeignet zur pulmonalen anwendungInfo
- Publication number
- ATE285755T1 ATE285755T1 AT00959327T AT00959327T ATE285755T1 AT E285755 T1 ATE285755 T1 AT E285755T1 AT 00959327 T AT00959327 T AT 00959327T AT 00959327 T AT00959327 T AT 00959327T AT E285755 T1 ATE285755 T1 AT E285755T1
- Authority
- AT
- Austria
- Prior art keywords
- spray drying
- porous particles
- large porous
- particles available
- particles
- Prior art date
Links
- 239000002245 particle Substances 0.000 title abstract 3
- 230000002685 pulmonary effect Effects 0.000 title abstract 2
- 238000001694 spray drying Methods 0.000 title abstract 2
- 150000003904 phospholipids Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- 150000001735 carboxylic acids Chemical class 0.000 abstract 1
- 229940039227 diagnostic agent Drugs 0.000 abstract 1
- 239000000032 diagnostic agent Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 150000008105 phosphatidylcholines Chemical class 0.000 abstract 1
- 150000008104 phosphatidylethanolamines Chemical class 0.000 abstract 1
- 229940067605 phosphatidylethanolamines Drugs 0.000 abstract 1
- 229940067626 phosphatidylinositols Drugs 0.000 abstract 1
- 150000003905 phosphatidylinositols Chemical class 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Biophysics (AREA)
- Otolaryngology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15066299P | 1999-08-25 | 1999-08-25 | |
| PCT/US2000/023118 WO2001013892A2 (en) | 1999-08-25 | 2000-08-23 | Large porous particles by spray-drying |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE285755T1 true ATE285755T1 (de) | 2005-01-15 |
Family
ID=22535487
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00959327T ATE285755T1 (de) | 1999-08-25 | 2000-08-23 | Grosse poröse partikel erhältlich durch sprühtrocknung und geeignet zur pulmonalen anwendung |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1210069B1 (enExample) |
| JP (1) | JP2003507411A (enExample) |
| AT (1) | ATE285755T1 (enExample) |
| AU (1) | AU768299B2 (enExample) |
| CA (1) | CA2383491A1 (enExample) |
| DE (1) | DE60017152D1 (enExample) |
| WO (1) | WO2001013892A2 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6565885B1 (en) | 1997-09-29 | 2003-05-20 | Inhale Therapeutic Systems, Inc. | Methods of spray drying pharmaceutical compositions |
| US20060165606A1 (en) | 1997-09-29 | 2006-07-27 | Nektar Therapeutics | Pulmonary delivery particles comprising water insoluble or crystalline active agents |
| US7871598B1 (en) * | 2000-05-10 | 2011-01-18 | Novartis Ag | Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use |
| PT1280520E (pt) * | 2000-05-10 | 2014-12-16 | Novartis Ag | Pós à base de fosfolípidos para administração de fármacos |
| US6848197B2 (en) * | 2001-04-18 | 2005-02-01 | Advanced Inhalation Research, Inc. | Control of process humidity to produce large, porous particles |
| JP2004528339A (ja) * | 2001-04-26 | 2004-09-16 | ネクター セラピューティクス | 気道に対して又は気道を介して高分子を送達するための新規方法及び組成物 |
| GB0120123D0 (en) * | 2001-08-17 | 2001-10-10 | Upperton Ltd | Preparation of microparticles |
| CA2465779A1 (en) * | 2001-11-20 | 2003-05-30 | Advanced Inhalation Research, Inc. | Compositions for sustained action product delivery |
| ES2364636T3 (es) | 2001-12-19 | 2011-09-08 | Novartis Ag | Administración pulmonar de aminoglucósidos. |
| AU2003287132B2 (en) * | 2002-12-13 | 2009-03-12 | Adagit | Pharmaceutical porous particles |
| JP2012522009A (ja) * | 2009-03-26 | 2012-09-20 | パルマトリックス，インコーポレイテッド | 肺炎および人工呼吸器関連気管気管支炎を治療および予防するための方法 |
| RU2577698C2 (ru) | 2009-03-26 | 2016-03-20 | Пулмэтрикс, Инк. | Сухие порошкообразные составы и способы лечения легочных заболеваний |
| CA2809666C (en) * | 2010-08-30 | 2020-09-22 | Michael M. Lipp | Dry powder formulations and methods for treating pulmonary diseases |
| US20130164338A1 (en) | 2010-08-30 | 2013-06-27 | Pulmatrix, Inc. | Treatment of cystic fibrosis using calcium lactate, leucine and sodium chloride in a respiraple dry powder |
| ES2710537T3 (es) * | 2010-09-29 | 2019-04-25 | Pulmatrix Operating Co Inc | Polvos secos catiónicos |
| RU2640921C2 (ru) | 2010-09-29 | 2018-01-12 | Пулмэтрикс, Инк. | Катионы одновалентных металлов сухих порошков для ингаляций |
| CA2865972C (en) | 2012-02-29 | 2022-01-04 | Pulmatrix, Inc. | Inhalable dry powders |
| MX2015013845A (es) | 2013-04-01 | 2016-05-09 | Pulmatrix Inc | Polvos secos de tiotropio. |
| AU2015213678C1 (en) | 2014-02-10 | 2019-03-21 | Respivant Sciences Gmbh | Mast cell stabilizers treatment for systemic disorders |
| EP3104854B1 (en) | 2014-02-10 | 2020-04-08 | Respivant Sciences GmbH | Mast cell stabilizers for lung disease treatment |
| CA2965759C (en) | 2014-10-31 | 2023-12-12 | Glaxosmithkline Intellectual Property Development Limited | Powdered polypeptides with decreased disulfide impurities comprising divalent cationic materials |
| US10238625B2 (en) | 2015-08-07 | 2019-03-26 | Respivant Sciences Gmbh | Methods for the treatment of mast cell related disorders with mast cell stabilizers |
| US10265296B2 (en) | 2015-08-07 | 2019-04-23 | Respivant Sciences Gmbh | Methods for the treatment of systemic disorders treatable with mast cell stabilizers, including mast cell related disorders |
| CA3035528A1 (en) | 2016-08-31 | 2018-03-08 | Respivant Sciences Gmbh | Cromolyn compositions for treatment of chronic cough due to idiopathic pulmonary fibrosis |
| AU2017339366A1 (en) | 2016-10-07 | 2019-04-11 | Respivant Sciences Gmbh | Cromolyn compositions for treatment of pulmonary fibrosis |
| CA3133804A1 (en) * | 2019-03-22 | 2020-10-01 | Mannkind Corporation | Inhalable dry powders |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6582728B1 (en) * | 1992-07-08 | 2003-06-24 | Inhale Therapeutic Systems, Inc. | Spray drying of macromolecules to produce inhaleable dry powders |
| WO1997026863A1 (de) * | 1996-01-24 | 1997-07-31 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Verfahren zur herstellung von pulverförmigen lungensurfactant-zubereitungen |
| US5855913A (en) * | 1997-01-16 | 1999-01-05 | Massachusetts Instite Of Technology | Particles incorporating surfactants for pulmonary drug delivery |
| EP0954282B1 (en) * | 1997-01-16 | 2005-01-19 | Massachusetts Institute Of Technology | Preparation of particles for inhalation |
-
2000
- 2000-08-23 EP EP00959327A patent/EP1210069B1/en not_active Expired - Lifetime
- 2000-08-23 JP JP2001518030A patent/JP2003507411A/ja not_active Withdrawn
- 2000-08-23 DE DE60017152T patent/DE60017152D1/de not_active Expired - Lifetime
- 2000-08-23 AT AT00959327T patent/ATE285755T1/de not_active IP Right Cessation
- 2000-08-23 AU AU70666/00A patent/AU768299B2/en not_active Ceased
- 2000-08-23 WO PCT/US2000/023118 patent/WO2001013892A2/en not_active Ceased
- 2000-08-23 CA CA002383491A patent/CA2383491A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1210069A2 (en) | 2002-06-05 |
| EP1210069B1 (en) | 2004-12-29 |
| AU768299B2 (en) | 2003-12-04 |
| DE60017152D1 (de) | 2005-02-03 |
| WO2001013892A3 (en) | 2001-06-21 |
| WO2001013892A2 (en) | 2001-03-01 |
| AU7066600A (en) | 2001-03-19 |
| JP2003507411A (ja) | 2003-02-25 |
| CA2383491A1 (en) | 2001-03-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |