ATE285755T1 - Grosse poröse partikel erhältlich durch sprühtrocknung und geeignet zur pulmonalen anwendung - Google Patents

Grosse poröse partikel erhältlich durch sprühtrocknung und geeignet zur pulmonalen anwendung

Info

Publication number
ATE285755T1
ATE285755T1 AT00959327T AT00959327T ATE285755T1 AT E285755 T1 ATE285755 T1 AT E285755T1 AT 00959327 T AT00959327 T AT 00959327T AT 00959327 T AT00959327 T AT 00959327T AT E285755 T1 ATE285755 T1 AT E285755T1
Authority
AT
Austria
Prior art keywords
spray drying
porous particles
large porous
particles available
particles
Prior art date
Application number
AT00959327T
Other languages
English (en)
Inventor
Michael M Lipp
Richard P Batycky
Giovanni Caponetti
Original Assignee
Advanced Inhalation Res Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advanced Inhalation Res Inc filed Critical Advanced Inhalation Res Inc
Application granted granted Critical
Publication of ATE285755T1 publication Critical patent/ATE285755T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
AT00959327T 1999-08-25 2000-08-23 Grosse poröse partikel erhältlich durch sprühtrocknung und geeignet zur pulmonalen anwendung ATE285755T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15066299P 1999-08-25 1999-08-25
PCT/US2000/023118 WO2001013892A2 (en) 1999-08-25 2000-08-23 Large porous particles by spray-drying

Publications (1)

Publication Number Publication Date
ATE285755T1 true ATE285755T1 (de) 2005-01-15

Family

ID=22535487

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00959327T ATE285755T1 (de) 1999-08-25 2000-08-23 Grosse poröse partikel erhältlich durch sprühtrocknung und geeignet zur pulmonalen anwendung

Country Status (7)

Country Link
EP (1) EP1210069B1 (de)
JP (1) JP2003507411A (de)
AT (1) ATE285755T1 (de)
AU (1) AU768299B2 (de)
CA (1) CA2383491A1 (de)
DE (1) DE60017152D1 (de)
WO (1) WO2001013892A2 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
AU6124601A (en) * 2000-05-10 2001-11-20 Alliance Pharmaceutical Corporation Phospholipid-based powders for drug delivery
US6848197B2 (en) 2001-04-18 2005-02-01 Advanced Inhalation Research, Inc. Control of process humidity to produce large, porous particles
WO2002087542A1 (en) * 2001-04-26 2002-11-07 Inhale Therapeutic Systems, Inc. Novel methods and compositions for delivering macromolecules to or via the respiratory tract
GB0120123D0 (en) * 2001-08-17 2001-10-10 Upperton Ltd Preparation of microparticles
WO2003043586A2 (en) * 2001-11-20 2003-05-30 Advanced Inhalation Research, Inc. Compositions for sustained action product delivery
JP2005514393A (ja) 2001-12-19 2005-05-19 ネクター セラピューティクス アミノグリコシドの肺への供給
CA2509216A1 (en) * 2002-12-13 2004-07-01 Adagit Pharmaceutical porous particles
EP2410985A2 (de) * 2009-03-26 2012-02-01 Pulmatrix, Inc. Verfahren zur behandlung und prophylaxe von pneumonie und tracheobronchitis im zusammenhang mit beatmungsgeräten
JP5671001B2 (ja) * 2009-03-26 2015-02-18 パルマトリックス，インコーポレイテッド 肺疾患を治療するための乾燥粉末製剤および方法
EP2448571B1 (de) 2010-08-30 2013-06-12 Pulmatrix, Inc. Einatembares trockenpulver mit calciumlactat, natriumchlorid und leukin
EP2611438B1 (de) * 2010-08-30 2020-04-01 Pulmatrix Operating Company, Inc. Trockenpulverformulierungen und verfahren zur behandlung von lungenerkrankugen
MX354828B (es) 2010-09-29 2018-03-22 Pulmatrix Operating Co Inc Polvos secos de cationes metálicos monovalentes para inhalación.
DK3470057T3 (da) * 2010-09-29 2021-11-22 Pulmatrix Operating Co Inc Kationiske tørpulvere omfattende magnesiumsalt
CN107596518B (zh) 2012-02-29 2021-04-23 普马特里克斯营业公司 可吸入干粉剂
WO2014165303A1 (en) 2013-04-01 2014-10-09 Pulmatrix, Inc. Tiotropium dry powders
SI3104853T1 (sl) 2014-02-10 2020-03-31 Respivant Sciences Gmbh Zdravljenje s stabilizatorji mastocitov za sistemske motnje
US20150224078A1 (en) 2014-02-10 2015-08-13 Patara Pharma, LLC Methods for the Treatment of Lung Diseases with Mast Cell Stabilizers
MX2017005692A (es) 2014-10-31 2017-08-07 Glaxosmithkline Ip Dev Ltd Formulacion en polvo.
US10238625B2 (en) 2015-08-07 2019-03-26 Respivant Sciences Gmbh Methods for the treatment of mast cell related disorders with mast cell stabilizers
WO2017027402A1 (en) 2015-08-07 2017-02-16 Patara Pharma, LLC Methods for the treatment of systemic disorders treatable with mast cell stabilizers, including mast cell related disorders
CA3035528A1 (en) 2016-08-31 2018-03-08 Respivant Sciences Gmbh Cromolyn compositions for treatment of chronic cough due to idiopathic pulmonary fibrosis
EP3522983A4 (de) 2016-10-07 2020-06-03 Respivant Sciences GmbH Cromolynzusammensetzung zur behandlung von lungenfibrose
CA3133804A1 (en) * 2019-03-22 2020-10-01 Mannkind Corporation Inhalable dry powders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6582728B1 (en) * 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
WO1997026863A1 (de) * 1996-01-24 1997-07-31 Byk Gulden Lomberg Chemische Fabrik Gmbh Verfahren zur herstellung von pulverförmigen lungensurfactant-zubereitungen
US5855913A (en) * 1997-01-16 1999-01-05 Massachusetts Instite Of Technology Particles incorporating surfactants for pulmonary drug delivery
PT954282E (pt) * 1997-01-16 2005-06-30 Massachusetts Inst Technology Preparacao de particulas para inalacao

Also Published As

Publication number Publication date
WO2001013892A3 (en) 2001-06-21
AU768299B2 (en) 2003-12-04
EP1210069A2 (de) 2002-06-05
AU7066600A (en) 2001-03-19
WO2001013892A2 (en) 2001-03-01
CA2383491A1 (en) 2001-03-01
JP2003507411A (ja) 2003-02-25
EP1210069B1 (de) 2004-12-29
DE60017152D1 (de) 2005-02-03

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