ATE28569T1 - Zusammensetzung, die einen radiomarkierten antikoerper enthaelt, ausruestung zu ihrer herstellung und ausruestung zur krebs- oder tumorbestimmung, die diese zusammensetzung enthaelt. - Google Patents

Zusammensetzung, die einen radiomarkierten antikoerper enthaelt, ausruestung zu ihrer herstellung und ausruestung zur krebs- oder tumorbestimmung, die diese zusammensetzung enthaelt.

Info

Publication number
ATE28569T1
ATE28569T1 AT80303614T AT80303614T ATE28569T1 AT E28569 T1 ATE28569 T1 AT E28569T1 AT 80303614 T AT80303614 T AT 80303614T AT 80303614 T AT80303614 T AT 80303614T AT E28569 T1 ATE28569 T1 AT E28569T1
Authority
AT
Austria
Prior art keywords
composition
hcg
equipment
cancer
antibody
Prior art date
Application number
AT80303614T
Other languages
English (en)
Inventor
Scott W Burchiel
David R Crockford
Buck A Rhodes
Original Assignee
University Patents Inc
Summa Medical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Patents Inc, Summa Medical Corp filed Critical University Patents Inc
Application granted granted Critical
Publication of ATE28569T1 publication Critical patent/ATE28569T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/806—Antigenic peptides or proteins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/828—Cancer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicinal Preparation (AREA)
  • Supports For Pipes And Cables (AREA)
AT80303614T 1979-10-29 1980-10-14 Zusammensetzung, die einen radiomarkierten antikoerper enthaelt, ausruestung zu ihrer herstellung und ausruestung zur krebs- oder tumorbestimmung, die diese zusammensetzung enthaelt. ATE28569T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/089,153 US4311688A (en) 1979-10-29 1979-10-29 Composition and method for cancer detection in humans
EP80303614A EP0028092B1 (de) 1979-10-29 1980-10-14 Zusammensetzung, die einen radiomarkierten Antikörper enthält, Ausrüstung zu ihrer Herstellung und Ausrüstung zur Krebs- oder Tumorbestimmung, die diese Zusammensetzung enthält

Publications (1)

Publication Number Publication Date
ATE28569T1 true ATE28569T1 (de) 1987-08-15

Family

ID=22215979

Family Applications (1)

Application Number Title Priority Date Filing Date
AT80303614T ATE28569T1 (de) 1979-10-29 1980-10-14 Zusammensetzung, die einen radiomarkierten antikoerper enthaelt, ausruestung zu ihrer herstellung und ausruestung zur krebs- oder tumorbestimmung, die diese zusammensetzung enthaelt.

Country Status (13)

Country Link
US (2) US4311688A (de)
EP (1) EP0028092B1 (de)
JP (1) JPS5695119A (de)
AT (1) ATE28569T1 (de)
AU (1) AU6377280A (de)
BR (1) BR8006935A (de)
CA (1) CA1152431A (de)
DE (1) DE3071996D1 (de)
DK (1) DK455780A (de)
FI (1) FI803381A7 (de)
IL (1) IL60780A (de)
NO (1) NO803213L (de)
ZA (1) ZA805813B (de)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4311688A (en) * 1979-10-29 1982-01-19 Serono Laboratories Inc. Composition and method for cancer detection in humans
USRE32417E (en) * 1979-10-29 1987-05-12 Summa Medical Corporation Radiolabeled antibody to anti-tumor associated antigen and process
US4472371A (en) * 1979-10-29 1984-09-18 Summa Medical Corporation Radiolabeled antibody to anti-tumor associated antigen and process
US4855126A (en) * 1980-07-10 1989-08-08 Chembiomed Ltd. Method to detect T-antigen delayed hypersensitivity
WO1983001004A1 (en) * 1981-09-28 1983-03-31 Roberto Luis Ceriani Specific mammary gland labelling
US4584268A (en) * 1981-10-13 1986-04-22 Ceriani Roberto Luis Method and compositions for carcinoma diagnosis
DE3239410A1 (de) * 1981-10-27 1983-05-19 Hybritech Inc., 92121 San Diego, Calif. Monoklonale antikoerper zu tumorassoziiertem antigen, zusammensetzungen, welche diese enthalten und deren anwendung zum tumornachweis
CA1225930A (en) * 1982-06-07 1987-08-25 Otto A. Gansow Metal chelate conjugated monoclonal antibodies
US4454106A (en) * 1982-06-07 1984-06-12 Gansow Otto A Use of metal chelate conjugated monoclonal antibodies
US4472509A (en) * 1982-06-07 1984-09-18 Gansow Otto A Metal chelate conjugated monoclonal antibodies
US4624846A (en) * 1983-07-29 1986-11-25 Immunomedics, Inc. Method for enhancing target specificity of antibody localization and clearance of non-target diagnostic and therapeutic principles
EP0149709B2 (de) * 1983-07-29 1995-11-29 Milton David Goldenberg Verfahren zur Erhöhung der Zielspezifizität in Antikörperbestimmungen und zur Räumung von nichtzielspezifischen diagnostischen und therapeutischen Faktoren
US4782840A (en) * 1984-03-02 1988-11-08 Neoprobe Corporation Method for locating, differentiating, and removing neoplasms
US4652440A (en) * 1984-05-03 1987-03-24 Paik Chang H Method of stably radiolabeling antibodies with technetium and rhenium
US4674480A (en) * 1984-05-25 1987-06-23 Lemelson Jerome H Drug compositions and methods of applying same
US4665897A (en) * 1984-05-25 1987-05-19 Lemelson Jerome H Composition and method for detecting and treating cancer
JPS6117065A (ja) * 1984-07-04 1986-01-25 Mitsui Toatsu Chem Inc ヒト絨毛性ゴナドトロピンの測定試薬
US4689222A (en) * 1985-01-18 1987-08-25 Mcmichael John Methods and materials for alleviation of pain symptoms of malignant neoplasia
US4692332A (en) * 1985-01-18 1987-09-08 Mcmichael John Immunotherapeutic methods and compositions employing antigens characteristic of malignant neoplasms
US4880626A (en) * 1985-01-18 1989-11-14 Mcmichael John Immunotherapeutic methods and compositions for the treatment of diseases of viral origin, including acquired immune deficiency syndrome
US4826672A (en) * 1985-06-07 1989-05-02 President And Fellows Of Harvard College Astatinated organic compounds
US4830847A (en) * 1985-06-28 1989-05-16 The Procter & Gamble Company Diphosphonate-derivatized macromolecules
US5776093A (en) * 1985-07-05 1998-07-07 Immunomedics, Inc. Method for imaging and treating organs and tissues
US4735210A (en) * 1985-07-05 1988-04-05 Immunomedics, Inc. Lymphographic and organ imaging method and kit
GB8519457D0 (en) * 1985-08-02 1985-09-11 Faulk Ward Page Tumour imaging agents
EP0252951A4 (de) * 1986-01-06 1988-09-07 Univ Melbourne Technetium-antikörper konjugate.
US4877868A (en) * 1986-03-12 1989-10-31 Neorx Corporation Radionuclide antibody coupling
US5320941A (en) * 1986-06-06 1994-06-14 Dallan Young DNA sequence encoding mas onhcogene, polypeptides encoded therefrom and diagnostic and other methods based therefrom
US4863713A (en) * 1986-06-23 1989-09-05 The Board Of Trustees Of Leland Stanford Jr. Univ. Method and system for administering therapeutic and diagnostic agents
US4762701A (en) * 1986-10-31 1988-08-09 Smithkline Beckman Corporation In vivo cellular tracking
US4877599A (en) * 1986-11-10 1989-10-31 New England Deaconess Hospital Corporation Detection of vascular disease with labelled antibodies
DE3728599A1 (de) * 1986-12-10 1988-06-23 Hoechst Ag Verfahren zur herstellung einer mit technetium-99m-markierten organspezifischen substanz
US5053493A (en) * 1987-04-02 1991-10-01 Centocor Cardiovascular Imaging Partners, L.P. Method for labeling antibodies with a metal ion
US5648471A (en) * 1987-12-03 1997-07-15 Centocor, Inc. One vial method for labeling antibodies with Technetium-99m
US5084266A (en) * 1988-02-03 1992-01-28 The University Of Melbourne Method for tumor imaging utilizing a labelled tumor specific antibody and a non-tumor reactive antibody
US4867962A (en) * 1988-02-26 1989-09-19 Neorx Corporation Functionally specific antibodies
US5128119A (en) * 1989-06-12 1992-07-07 Immunomedics, Inc. Methods for technetium/rhenium labeling of f(ab1)2 fragments
US5001052A (en) * 1989-02-09 1991-03-19 Wisconsin Alumni Research Foundation Immunoassay for FHAP and antibody useful therewith
US5179008A (en) * 1989-02-09 1993-01-12 Wisconsin Alumni Research Foundation Hybridoma and monoclonal antibody to FHAP
US5279968A (en) * 1989-07-20 1994-01-18 Syncor International Corporation Method of labelling leucocytes with Tc-99m, d,1-HMPAO
US5078985A (en) * 1989-08-09 1992-01-07 Rhomed, Incorporated Radiolabeling antibodies and other proteins with technetium or rhenium by regulated reduction
US5346687A (en) * 1989-08-09 1994-09-13 Rhomed Incorporated Direct radiolabeling of antibody against stage specific embryonic antigen for diagnostic imaging
US5460785A (en) * 1989-08-09 1995-10-24 Rhomed Incorporated Direct labeling of antibodies and other protein with metal ions
DE69032742T2 (de) * 1989-08-09 1999-06-17 Rhomed, Inc., Albuquerque, N.Mex. Direkte radioetikettierung von antikörpern und sonstigen proteinen mittels technetium oder rhenium
CA1340250C (en) * 1989-09-18 1998-12-15 Hans J. Hansen Method for rapidly radiolabeling monovalent antibody fragments with technetium
US5130129A (en) * 1990-03-06 1992-07-14 The Regents Of The University Of California Method for enhancing antibody transport through capillary barriers
US5011676A (en) * 1990-03-27 1991-04-30 Thomas Jefferson University Method to directly radiolabel antibodies for diagnostic imaging and therapy
ATE147637T1 (de) * 1991-02-05 1997-02-15 Cis Bio Int Verfahren zur herstellung einer mit technetium- 99m markierten organspezifischen substanz
CA2135882A1 (en) * 1992-05-15 1993-11-25 Ernest K. J. Pauwels Method of preparing a diagnostic agent for detecting inflammations
EP0654973A4 (de) * 1992-07-21 1995-08-09 Gen Hospital Corp Anordnung zur abgabe von medikamenten an das lymphgewebe.
US5756825A (en) * 1992-09-08 1998-05-26 Safavy; Ahmad Hydroxamic acid-based bifunctional chelating compounds
US5670132A (en) * 1994-09-20 1997-09-23 Immunomedics, Inc. Modified radioantibody fragments for reduced renal uptake
US5900377A (en) * 1997-03-03 1999-05-04 Syncor International Corporation Method for isolating and radiolabeling leukocytes for use in vivo
US6080384A (en) * 1997-03-25 2000-06-27 American Biogenetic Sciences, Inc. Methods for radionuclide-labeling of biomolecules and kits utilizing the same
US7666609B1 (en) * 1998-12-01 2010-02-23 Shanghai Cp Guojian Pharmaceutical Co. Ltd. Method and composition for diagnosis of melanocytic lesions
RU2154468C1 (ru) * 1999-11-09 2000-08-20 Родионов Сергей Юрьевич Способ получения таблеток альфа-фетопротеина
US20020117169A1 (en) 2001-02-27 2002-08-29 Kurz Daniel R. Cover and applicator for a portion of a mammalian body
ATE394675T1 (de) * 2002-10-11 2008-05-15 Sentina Biotechnology Inc Verfahren zum nachweis von brustkrebs
DK1408106T3 (da) * 2002-10-11 2007-06-11 Sentoclone Ab Cancer immunterapi
CN1279056C (zh) * 2003-06-06 2006-10-11 马菁 肿瘤相关抗原sm5－1的特异性抗体及其应用
US20050232926A1 (en) * 2003-06-06 2005-10-20 Oncomax Acquisition Corp. Antibodies specific for cancer associated antigen SM5-1 and uses thereof
EP1711618B1 (de) 2003-12-23 2010-08-04 Mount Sinai Hospital Corporation Verfahren zum nachweis von mit endometrialer krankheit oder phase assoziierten markern
US8101173B2 (en) * 2005-12-21 2012-01-24 Sentoclone International Ab Method for treating urinary bladder cancer
WO2007071390A1 (en) * 2005-12-21 2007-06-28 Sentoclone Ab Method for treating malignant melanoma
EP1966369B1 (de) * 2005-12-21 2010-10-06 Sentoclone AB Verfahren zur expansion tumorreaktiver t-lymphozyten zur immuntherapie von patienten mit krebs
WO2007071389A1 (en) * 2005-12-21 2007-06-28 Sentoclone Ab Method for treating disseminated cancer
EP2087152B1 (de) 2006-10-27 2015-03-11 Walfish, Paul Endometriale biomarker
WO2008141318A1 (en) * 2007-05-14 2008-11-20 Dr. Susan Love Research Foundation Device for determining risk of developing breast cancer and method thereof
CA2618163A1 (en) 2008-02-07 2009-08-07 K. W. Michael Siu Head and neck cancer biomarkers
WO2010006808A1 (en) * 2008-07-18 2010-01-21 Sentoclone Ab Composition comprising in vitro expanded t-lymphocytes and vessel formation inhibitors suitable in the treatment of cancer
US9040464B2 (en) 2010-08-16 2015-05-26 Mount Sinai Hosptial Markers of the male urogenital tract
US8668900B2 (en) 2011-02-15 2014-03-11 Kuwait University Cancer-imaging agent and method of radioimaging using the same
US20230139592A1 (en) 2016-12-22 2023-05-04 Wake Forest University Health Sciences Sirp-gamma targeted agents for use in the treatment of cancer
WO2022038198A1 (en) 2020-08-19 2022-02-24 Diamidex Monosaccharide compound for the labelling of cell secretion

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4010251A (en) * 1974-12-16 1977-03-01 Green Allan M Scanning agent composition and use in imaging liver and for biliary function
FR2310748A1 (fr) * 1975-05-15 1976-12-10 Abramovici J Procede de marquage de proteines a l'aide du technetium
US4116776A (en) * 1976-04-19 1978-09-26 International Radioimmune Systems, Inc. Diagnostic blood test and kit for detecting human chorionic gonadotropin
US4323546A (en) * 1978-05-22 1982-04-06 Nuc Med Inc. Method and composition for cancer detection in humans
US4311688A (en) * 1979-10-29 1982-01-19 Serono Laboratories Inc. Composition and method for cancer detection in humans
DE3004234A1 (de) * 1980-02-06 1981-08-13 Desowag-Bayer Holzschutz GmbH, 4000 Düsseldorf Wundbehandlungs-, wundverschluss- und wundschutzmittel fuer baeume
US4348376A (en) * 1980-03-03 1982-09-07 Goldenberg Milton David Tumor localization and therapy with labeled anti-CEA antibody
US4331647A (en) * 1980-03-03 1982-05-25 Goldenberg Milton David Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers

Also Published As

Publication number Publication date
ZA805813B (en) 1981-09-30
EP0028092B1 (de) 1987-07-29
CA1152431A (en) 1983-08-23
NO803213L (no) 1981-04-30
US4478815A (en) 1984-10-23
AU6377280A (en) 1981-05-07
DK455780A (da) 1981-04-30
JPS6138173B2 (de) 1986-08-28
BR8006935A (pt) 1981-05-05
US4311688A (en) 1982-01-19
FI803381L (fi) 1981-04-30
IL60780A (en) 1984-02-29
FI803381A7 (fi) 1981-04-30
EP0028092A3 (en) 1982-02-03
DE3071996D1 (en) 1987-09-03
EP0028092A2 (de) 1981-05-06
JPS5695119A (en) 1981-08-01

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