ATE28569T1 - Zusammensetzung, die einen radiomarkierten antikoerper enthaelt, ausruestung zu ihrer herstellung und ausruestung zur krebs- oder tumorbestimmung, die diese zusammensetzung enthaelt. - Google Patents
Zusammensetzung, die einen radiomarkierten antikoerper enthaelt, ausruestung zu ihrer herstellung und ausruestung zur krebs- oder tumorbestimmung, die diese zusammensetzung enthaelt.Info
- Publication number
- ATE28569T1 ATE28569T1 AT80303614T AT80303614T ATE28569T1 AT E28569 T1 ATE28569 T1 AT E28569T1 AT 80303614 T AT80303614 T AT 80303614T AT 80303614 T AT80303614 T AT 80303614T AT E28569 T1 ATE28569 T1 AT E28569T1
- Authority
- AT
- Austria
- Prior art keywords
- composition
- hcg
- equipment
- cancer
- antibody
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/806—Antigenic peptides or proteins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/828—Cancer
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicinal Preparation (AREA)
- Supports For Pipes And Cables (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/089,153 US4311688A (en) | 1979-10-29 | 1979-10-29 | Composition and method for cancer detection in humans |
EP80303614A EP0028092B1 (de) | 1979-10-29 | 1980-10-14 | Zusammensetzung, die einen radiomarkierten Antikörper enthält, Ausrüstung zu ihrer Herstellung und Ausrüstung zur Krebs- oder Tumorbestimmung, die diese Zusammensetzung enthält |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE28569T1 true ATE28569T1 (de) | 1987-08-15 |
Family
ID=22215979
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT80303614T ATE28569T1 (de) | 1979-10-29 | 1980-10-14 | Zusammensetzung, die einen radiomarkierten antikoerper enthaelt, ausruestung zu ihrer herstellung und ausruestung zur krebs- oder tumorbestimmung, die diese zusammensetzung enthaelt. |
Country Status (13)
Country | Link |
---|---|
US (2) | US4311688A (de) |
EP (1) | EP0028092B1 (de) |
JP (1) | JPS5695119A (de) |
AT (1) | ATE28569T1 (de) |
AU (1) | AU6377280A (de) |
BR (1) | BR8006935A (de) |
CA (1) | CA1152431A (de) |
DE (1) | DE3071996D1 (de) |
DK (1) | DK455780A (de) |
FI (1) | FI803381L (de) |
IL (1) | IL60780A (de) |
NO (1) | NO803213L (de) |
ZA (1) | ZA805813B (de) |
Families Citing this family (73)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4311688A (en) * | 1979-10-29 | 1982-01-19 | Serono Laboratories Inc. | Composition and method for cancer detection in humans |
USRE32417E (en) * | 1979-10-29 | 1987-05-12 | Summa Medical Corporation | Radiolabeled antibody to anti-tumor associated antigen and process |
US4472371A (en) * | 1979-10-29 | 1984-09-18 | Summa Medical Corporation | Radiolabeled antibody to anti-tumor associated antigen and process |
US4855126A (en) * | 1980-07-10 | 1989-08-08 | Chembiomed Ltd. | Method to detect T-antigen delayed hypersensitivity |
EP0090025A4 (de) * | 1981-09-28 | 1984-01-12 | Roberto Luis Ceriani | Kennzeichnung einer spezifischen brustdrüse. |
US4584268A (en) * | 1981-10-13 | 1986-04-22 | Ceriani Roberto Luis | Method and compositions for carcinoma diagnosis |
ES8404857A1 (es) * | 1981-10-27 | 1984-05-16 | Hybritech Inc | Un procedimiento para preparar un anticuerpo monoclonal para un antigeno asociado a un tumor. |
US4472509A (en) * | 1982-06-07 | 1984-09-18 | Gansow Otto A | Metal chelate conjugated monoclonal antibodies |
US4454106A (en) * | 1982-06-07 | 1984-06-12 | Gansow Otto A | Use of metal chelate conjugated monoclonal antibodies |
GB2122641B (en) * | 1982-06-07 | 1986-08-06 | Otto A Gansow | Metal chelate conjugated monoclonal antibodies where in the metal is an emitter |
EP0149709B2 (de) * | 1983-07-29 | 1995-11-29 | Milton David Goldenberg | Verfahren zur Erhöhung der Zielspezifizität in Antikörperbestimmungen und zur Räumung von nichtzielspezifischen diagnostischen und therapeutischen Faktoren |
US4624846A (en) * | 1983-07-29 | 1986-11-25 | Immunomedics, Inc. | Method for enhancing target specificity of antibody localization and clearance of non-target diagnostic and therapeutic principles |
US4782840A (en) * | 1984-03-02 | 1988-11-08 | Neoprobe Corporation | Method for locating, differentiating, and removing neoplasms |
US4652440A (en) * | 1984-05-03 | 1987-03-24 | Paik Chang H | Method of stably radiolabeling antibodies with technetium and rhenium |
US4665897A (en) * | 1984-05-25 | 1987-05-19 | Lemelson Jerome H | Composition and method for detecting and treating cancer |
US4674480A (en) * | 1984-05-25 | 1987-06-23 | Lemelson Jerome H | Drug compositions and methods of applying same |
JPS6117065A (ja) * | 1984-07-04 | 1986-01-25 | Mitsui Toatsu Chem Inc | ヒト絨毛性ゴナドトロピンの測定試薬 |
US4692332A (en) * | 1985-01-18 | 1987-09-08 | Mcmichael John | Immunotherapeutic methods and compositions employing antigens characteristic of malignant neoplasms |
US4880626A (en) * | 1985-01-18 | 1989-11-14 | Mcmichael John | Immunotherapeutic methods and compositions for the treatment of diseases of viral origin, including acquired immune deficiency syndrome |
US4689222A (en) * | 1985-01-18 | 1987-08-25 | Mcmichael John | Methods and materials for alleviation of pain symptoms of malignant neoplasia |
US4826672A (en) * | 1985-06-07 | 1989-05-02 | President And Fellows Of Harvard College | Astatinated organic compounds |
US4830847A (en) * | 1985-06-28 | 1989-05-16 | The Procter & Gamble Company | Diphosphonate-derivatized macromolecules |
US4735210A (en) * | 1985-07-05 | 1988-04-05 | Immunomedics, Inc. | Lymphographic and organ imaging method and kit |
US5776093A (en) | 1985-07-05 | 1998-07-07 | Immunomedics, Inc. | Method for imaging and treating organs and tissues |
GB8519457D0 (en) * | 1985-08-02 | 1985-09-11 | Faulk Ward Page | Tumour imaging agents |
WO1987004164A1 (en) * | 1986-01-06 | 1987-07-16 | The University Of Melbourne | Technetium-antibody conjugate |
US4877868A (en) * | 1986-03-12 | 1989-10-31 | Neorx Corporation | Radionuclide antibody coupling |
US5320941A (en) * | 1986-06-06 | 1994-06-14 | Dallan Young | DNA sequence encoding mas onhcogene, polypeptides encoded therefrom and diagnostic and other methods based therefrom |
US4863713A (en) * | 1986-06-23 | 1989-09-05 | The Board Of Trustees Of Leland Stanford Jr. Univ. | Method and system for administering therapeutic and diagnostic agents |
US4762701A (en) * | 1986-10-31 | 1988-08-09 | Smithkline Beckman Corporation | In vivo cellular tracking |
US4877599A (en) * | 1986-11-10 | 1989-10-31 | New England Deaconess Hospital Corporation | Detection of vascular disease with labelled antibodies |
DE3728599A1 (de) * | 1986-12-10 | 1988-06-23 | Hoechst Ag | Verfahren zur herstellung einer mit technetium-99m-markierten organspezifischen substanz |
US5053493A (en) * | 1987-04-02 | 1991-10-01 | Centocor Cardiovascular Imaging Partners, L.P. | Method for labeling antibodies with a metal ion |
US5648471A (en) * | 1987-12-03 | 1997-07-15 | Centocor, Inc. | One vial method for labeling antibodies with Technetium-99m |
US5084266A (en) * | 1988-02-03 | 1992-01-28 | The University Of Melbourne | Method for tumor imaging utilizing a labelled tumor specific antibody and a non-tumor reactive antibody |
US4867962A (en) * | 1988-02-26 | 1989-09-19 | Neorx Corporation | Functionally specific antibodies |
US5128119A (en) * | 1989-06-12 | 1992-07-07 | Immunomedics, Inc. | Methods for technetium/rhenium labeling of f(ab1)2 fragments |
US5001052A (en) * | 1989-02-09 | 1991-03-19 | Wisconsin Alumni Research Foundation | Immunoassay for FHAP and antibody useful therewith |
US5179008A (en) * | 1989-02-09 | 1993-01-12 | Wisconsin Alumni Research Foundation | Hybridoma and monoclonal antibody to FHAP |
US5279968A (en) * | 1989-07-20 | 1994-01-18 | Syncor International Corporation | Method of labelling leucocytes with Tc-99m, d,1-HMPAO |
US5460785A (en) * | 1989-08-09 | 1995-10-24 | Rhomed Incorporated | Direct labeling of antibodies and other protein with metal ions |
US5078985A (en) * | 1989-08-09 | 1992-01-07 | Rhomed, Incorporated | Radiolabeling antibodies and other proteins with technetium or rhenium by regulated reduction |
US5346687A (en) * | 1989-08-09 | 1994-09-13 | Rhomed Incorporated | Direct radiolabeling of antibody against stage specific embryonic antigen for diagnostic imaging |
ATE172879T1 (de) * | 1989-08-09 | 1998-11-15 | Rhomed Inc | Direkte radioetikettierung von antikörpern und sonstigen proteinen mittels technetium oder rhenium |
CA1340250C (en) * | 1989-09-18 | 1998-12-15 | Hans J. Hansen | Method for rapidly radiolabeling monovalent antibody fragments with technetium |
US5130129A (en) * | 1990-03-06 | 1992-07-14 | The Regents Of The University Of California | Method for enhancing antibody transport through capillary barriers |
US5011676A (en) * | 1990-03-27 | 1991-04-30 | Thomas Jefferson University | Method to directly radiolabel antibodies for diagnostic imaging and therapy |
FI920459A (fi) * | 1991-02-05 | 1992-08-06 | Hoechst Ag | Foerfarande foer framstaellning av ett med teknetium-99m maerkt organspecifikt aemne. |
AU4288493A (en) * | 1992-05-15 | 1993-12-13 | Mallinckrodt Medical, Inc. | Method of preparing a diagnostic agent for detecting inflammations |
WO1994002068A1 (en) * | 1992-07-21 | 1994-02-03 | The General Hospital Corporation | System of drug delivery to the lymphatic tissues |
US5756825A (en) * | 1992-09-08 | 1998-05-26 | Safavy; Ahmad | Hydroxamic acid-based bifunctional chelating compounds |
US5670132A (en) * | 1994-09-20 | 1997-09-23 | Immunomedics, Inc. | Modified radioantibody fragments for reduced renal uptake |
US5900377A (en) * | 1997-03-03 | 1999-05-04 | Syncor International Corporation | Method for isolating and radiolabeling leukocytes for use in vivo |
US6080384A (en) * | 1997-03-25 | 2000-06-27 | American Biogenetic Sciences, Inc. | Methods for radionuclide-labeling of biomolecules and kits utilizing the same |
US7666609B1 (en) * | 1998-12-01 | 2010-02-23 | Shanghai Cp Guojian Pharmaceutical Co. Ltd. | Method and composition for diagnosis of melanocytic lesions |
US20020117169A1 (en) | 2001-02-27 | 2002-08-29 | Kurz Daniel R. | Cover and applicator for a portion of a mammalian body |
ES2282355T3 (es) * | 2002-10-11 | 2007-10-16 | Sentoclone Ab | Inmunoterapia de cancer. |
CA2501330A1 (en) * | 2002-10-11 | 2004-04-22 | Sentina Biotechnology Incorporated | Methods for detection of breast cancer |
CN1279056C (zh) * | 2003-06-06 | 2006-10-11 | 马菁 | 肿瘤相关抗原sm5-1的特异性抗体及其应用 |
US20050232926A1 (en) * | 2003-06-06 | 2005-10-20 | Oncomax Acquisition Corp. | Antibodies specific for cancer associated antigen SM5-1 and uses thereof |
AU2004303448A1 (en) | 2003-12-23 | 2005-07-07 | Mount Sinai Hospital | Methods for detecting markers associated with endometrial disease or phase |
AU2006328944B2 (en) * | 2005-12-21 | 2011-08-25 | Sentoclone International Ab | Method for treating disseminated cancer |
WO2007071388A1 (en) * | 2005-12-21 | 2007-06-28 | Sentoclone Ab | Improved method for expansion of tumour-reactive t-lymphocytes for immunotherapy of patients with cancer |
US8101173B2 (en) * | 2005-12-21 | 2012-01-24 | Sentoclone International Ab | Method for treating urinary bladder cancer |
AU2006328945B2 (en) * | 2005-12-21 | 2011-06-30 | Sentoclone International Ab | Method for treating malignant melanoma |
US8329399B2 (en) | 2006-10-27 | 2012-12-11 | Siu K W Michael | Endometrial biomarkers |
WO2008141318A1 (en) * | 2007-05-14 | 2008-11-20 | Dr. Susan Love Research Foundation | Device for determining risk of developing breast cancer and method thereof |
CA2618163A1 (en) | 2008-02-07 | 2009-08-07 | K. W. Michael Siu | Head and neck cancer biomarkers |
JP2011528326A (ja) * | 2008-07-18 | 2011-11-17 | セントクローネ インターナショナル エービー | インビトロ拡大されたtリンパ球及びガン治療に適切な血管形成インヒビターを含む組成物 |
US9040464B2 (en) | 2010-08-16 | 2015-05-26 | Mount Sinai Hosptial | Markers of the male urogenital tract |
US8668900B2 (en) | 2011-02-15 | 2014-03-11 | Kuwait University | Cancer-imaging agent and method of radioimaging using the same |
EP3559037A1 (de) | 2016-12-22 | 2019-10-30 | Wake Forest University Health Sciences | Auf sirp-gamma abzielende mittel zur behandlung von krebs |
EP4200613A1 (de) | 2020-08-19 | 2023-06-28 | Theraonco | Monosaccharidverbindung zur markierung der zellsekretion |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4010251A (en) * | 1974-12-16 | 1977-03-01 | Green Allan M | Scanning agent composition and use in imaging liver and for biliary function |
FR2310748A1 (fr) * | 1975-05-15 | 1976-12-10 | Abramovici J | Procede de marquage de proteines a l'aide du technetium |
US4116776A (en) * | 1976-04-19 | 1978-09-26 | International Radioimmune Systems, Inc. | Diagnostic blood test and kit for detecting human chorionic gonadotropin |
US4323546A (en) * | 1978-05-22 | 1982-04-06 | Nuc Med Inc. | Method and composition for cancer detection in humans |
US4311688A (en) * | 1979-10-29 | 1982-01-19 | Serono Laboratories Inc. | Composition and method for cancer detection in humans |
DE3004234A1 (de) * | 1980-02-06 | 1981-08-13 | Desowag-Bayer Holzschutz GmbH, 4000 Düsseldorf | Wundbehandlungs-, wundverschluss- und wundschutzmittel fuer baeume |
US4348376A (en) * | 1980-03-03 | 1982-09-07 | Goldenberg Milton David | Tumor localization and therapy with labeled anti-CEA antibody |
US4331647A (en) * | 1980-03-03 | 1982-05-25 | Goldenberg Milton David | Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers |
-
1979
- 1979-10-29 US US06/089,153 patent/US4311688A/en not_active Expired - Lifetime
-
1980
- 1980-08-06 IL IL60780A patent/IL60780A/xx unknown
- 1980-09-19 ZA ZA00805813A patent/ZA805813B/xx unknown
- 1980-10-14 AT AT80303614T patent/ATE28569T1/de not_active IP Right Cessation
- 1980-10-14 EP EP80303614A patent/EP0028092B1/de not_active Expired
- 1980-10-14 DE DE8080303614T patent/DE3071996D1/de not_active Expired
- 1980-10-28 NO NO803213A patent/NO803213L/no unknown
- 1980-10-28 JP JP15025580A patent/JPS5695119A/ja active Granted
- 1980-10-28 AU AU63772/80A patent/AU6377280A/en not_active Abandoned
- 1980-10-28 CA CA000363411A patent/CA1152431A/en not_active Expired
- 1980-10-28 FI FI803381A patent/FI803381L/fi not_active Application Discontinuation
- 1980-10-28 DK DK455780A patent/DK455780A/da unknown
- 1980-10-29 BR BR8006935A patent/BR8006935A/pt unknown
-
1981
- 1981-06-02 US US06/269,404 patent/US4478815A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JPS5695119A (en) | 1981-08-01 |
NO803213L (no) | 1981-04-30 |
IL60780A (en) | 1984-02-29 |
FI803381L (fi) | 1981-04-30 |
US4478815A (en) | 1984-10-23 |
US4311688A (en) | 1982-01-19 |
EP0028092A2 (de) | 1981-05-06 |
AU6377280A (en) | 1981-05-07 |
DE3071996D1 (en) | 1987-09-03 |
EP0028092B1 (de) | 1987-07-29 |
JPS6138173B2 (de) | 1986-08-28 |
EP0028092A3 (en) | 1982-02-03 |
ZA805813B (en) | 1981-09-30 |
DK455780A (da) | 1981-04-30 |
BR8006935A (pt) | 1981-05-05 |
CA1152431A (en) | 1983-08-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |