ATE284203T1 - Verfahren zur herstellung eines poly(vinyl)alkoholkryogels - Google Patents
Verfahren zur herstellung eines poly(vinyl)alkoholkryogelsInfo
- Publication number
- ATE284203T1 ATE284203T1 AT98918953T AT98918953T ATE284203T1 AT E284203 T1 ATE284203 T1 AT E284203T1 AT 98918953 T AT98918953 T AT 98918953T AT 98918953 T AT98918953 T AT 98918953T AT E284203 T1 ATE284203 T1 AT E284203T1
- Authority
- AT
- Austria
- Prior art keywords
- poly
- vinyl
- producing
- tissue
- hydrogel
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/52—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
- C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
- C08J3/075—Macromolecular gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30756—Cartilage endoprostheses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/23—Carbohydrates
- A61L2300/236—Glycosaminoglycans, e.g. heparin, hyaluronic acid, chondroitin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
- A61L2300/254—Enzymes, proenzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
- A61L2300/256—Antibodies, e.g. immunoglobulins, vaccines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
- A61L2300/414—Growth factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/42—Anti-thrombotic agents, anticoagulants, anti-platelet agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/426—Immunomodulating agents, i.e. cytokines, interleukins, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/432—Inhibitors, antagonists
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/64—Animal cells
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2329/00—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal, or ketal radical; Hydrolysed polymers of esters of unsaturated alcohols with saturated carboxylic acids; Derivatives of such polymer
- C08J2329/02—Homopolymers or copolymers of unsaturated alcohols
- C08J2329/04—Polyvinyl alcohol; Partially hydrolysed homopolymers or copolymers of esters of unsaturated alcohols with saturated carboxylic acids
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
- Y10S623/901—Method of manufacturing prosthetic device
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Dispersion Chemistry (AREA)
- Cell Biology (AREA)
- Botany (AREA)
- Zoology (AREA)
- Inorganic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4587597P | 1997-05-05 | 1997-05-05 | |
US08/932,029 US5981826A (en) | 1997-05-05 | 1997-09-17 | Poly(vinyl alcohol) cryogel |
PCT/US1998/009129 WO1998050017A1 (en) | 1997-05-05 | 1998-05-05 | Poly(vinyl alcohol) cryogel |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE284203T1 true ATE284203T1 (de) | 2004-12-15 |
Family
ID=26723293
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98918953T ATE284203T1 (de) | 1997-05-05 | 1998-05-05 | Verfahren zur herstellung eines poly(vinyl)alkoholkryogels |
Country Status (11)
Country | Link |
---|---|
US (3) | US5981826A (de) |
EP (2) | EP0991402B1 (de) |
JP (2) | JP3506718B2 (de) |
AT (1) | ATE284203T1 (de) |
AU (1) | AU728426B2 (de) |
CA (1) | CA2288793C (de) |
DE (1) | DE69828050T2 (de) |
DK (1) | DK0991402T3 (de) |
ES (1) | ES2232945T3 (de) |
PT (1) | PT991402E (de) |
WO (1) | WO1998050017A1 (de) |
Families Citing this family (174)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7195013B2 (en) * | 1993-11-09 | 2007-03-27 | Advanced Circulatory Systems, Inc. | Systems and methods for modulating autonomic function |
US7195012B2 (en) * | 2003-04-28 | 2007-03-27 | Advanced Circulatory Systems, Inc. | Systems and methods for reducing intracranial pressure |
US7082945B2 (en) * | 2003-04-28 | 2006-08-01 | Advanced Circulatory Systems, Inc. | Ventilator and methods for treating head trauma |
US20030008396A1 (en) * | 1999-03-17 | 2003-01-09 | Ku David N. | Poly(vinyl alcohol) hydrogel |
US6569417B2 (en) | 1997-10-10 | 2003-05-27 | Micro Therapeutics, Inc. | Methods for treating urinary incontinence in mammals |
US6268405B1 (en) * | 1999-05-04 | 2001-07-31 | Porex Surgical, Inc. | Hydrogels and methods of making and using same |
US6719797B1 (en) * | 1999-08-13 | 2004-04-13 | Bret A. Ferree | Nucleus augmentation with in situ formed hydrogels |
ATE257397T1 (de) * | 1999-10-29 | 2004-01-15 | Univ Drexel | Bindende hydrogele zum ersatz des nukleus pulposus |
US7214245B1 (en) * | 1999-10-29 | 2007-05-08 | Drexel University | Associating hydrogels for nucleus pulposus replacement in intervertebral discs |
AU4361601A (en) * | 2000-03-13 | 2001-09-24 | Biocure Inc | Hydrogel biomedical articles |
EP1263803B1 (de) * | 2000-03-13 | 2007-09-19 | BioCure, Inc. | Embolische zusammensetzungen |
US20030009213A1 (en) * | 2000-03-13 | 2003-01-09 | Jun Yang | Stent having cover with drug delivery capability |
US6652883B2 (en) * | 2000-03-13 | 2003-11-25 | Biocure, Inc. | Tissue bulking and coating compositions |
US6613082B2 (en) * | 2000-03-13 | 2003-09-02 | Jun Yang | Stent having cover with drug delivery capability |
US6629997B2 (en) * | 2000-03-27 | 2003-10-07 | Kevin A. Mansmann | Meniscus-type implant with hydrogel surface reinforced by three-dimensional mesh |
US7022135B2 (en) * | 2001-08-17 | 2006-04-04 | Medtronic, Inc. | Film with highly porous vascular graft prostheses |
SE0103404D0 (sv) * | 2001-10-12 | 2001-10-12 | Protista Internat Ab | Macroporous gel, ITS preparation and its use |
SE0103403D0 (sv) * | 2001-10-12 | 2001-10-12 | Protista Internat Ab | Separation medium, ITS preparation and ITS use |
US6783721B2 (en) * | 2001-10-30 | 2004-08-31 | Howmedica Osteonics Corp. | Method of making an ion treated hydrogel |
EA007594B1 (ru) * | 2001-11-26 | 2006-12-29 | Джинентех, Инк. | Конструкция катетера и области ее применения |
US7147661B2 (en) | 2001-12-20 | 2006-12-12 | Boston Scientific Santa Rosa Corp. | Radially expandable stent |
EP1497410A4 (de) * | 2002-04-01 | 2005-05-25 | Peter K Law | Zelltransplantation zur herzregenerierung |
US20040023579A1 (en) * | 2002-07-30 | 2004-02-05 | Kainth Arvinder Pal Singh | Fiber having controlled fiber-bed friction angles and/or cohesion values, and composites made from same |
US20040023589A1 (en) * | 2002-07-30 | 2004-02-05 | Kainth Arvinder Pal Singh | Superabsorbent materials having high, controlled gel-bed friction angles and composites made from the same |
US7297395B2 (en) * | 2002-07-30 | 2007-11-20 | Kimberly-Clark Worldwide, Inc. | Superabsorbent materials having low, controlled gel-bed friction angles and composites made from the same |
US7745532B2 (en) * | 2002-08-02 | 2010-06-29 | Cambridge Polymer Group, Inc. | Systems and methods for controlling and forming polymer gels |
US7485670B2 (en) * | 2002-08-02 | 2009-02-03 | Cambridge Polymer Group, Inc. | Systems and methods for controlling and forming polymer gels |
WO2005017000A1 (en) * | 2003-07-31 | 2005-02-24 | Cambridge Polymer Group | Systems and methods for controlling and forming polymer gels |
US7959636B2 (en) * | 2002-08-15 | 2011-06-14 | Arthrex, Inc. | Osteochondral repair using plug fashioned from whole distal femur or condyle formed of hydrogel composition |
US20040044320A1 (en) * | 2002-08-27 | 2004-03-04 | Kainth Arvinder Pal Singh | Composites having controlled friction angles and cohesion values |
US20040044321A1 (en) * | 2002-08-27 | 2004-03-04 | Kainth Arvinder Pal Singh | Superabsorbent materials having controlled gel-bed friction angles and cohesion values and composites made from same |
US7264634B2 (en) | 2002-09-20 | 2007-09-04 | Arthrex, Inc. | Method and instrumentation for osteochondral repair using preformed implants |
US7004971B2 (en) * | 2002-12-31 | 2006-02-28 | Depuy Acromed, Inc. | Annular nucleus pulposus replacement |
US20040143327A1 (en) * | 2003-01-17 | 2004-07-22 | Ku David N. | Solid implant |
US7766011B2 (en) | 2003-04-28 | 2010-08-03 | Advanced Circulatory Systems, Inc. | Positive pressure systems and methods for increasing blood pressure and circulation |
US20040253890A1 (en) * | 2003-06-13 | 2004-12-16 | Ostgard Estelle Anne | Fibers with lower edgewise compression strength and sap containing composites made from the same |
US20040253440A1 (en) * | 2003-06-13 | 2004-12-16 | Kainth Arvinder Pal Singh | Fiber having controlled fiber-bed friction angles and/or cohesion values, and composites made from same |
US9206414B2 (en) * | 2003-08-13 | 2015-12-08 | Axcelon Biopolymers Corporation | Anisotropic nanocomposite hydrogel |
US20050037082A1 (en) * | 2003-08-13 | 2005-02-17 | Wan-Kei Wan | Poly(vinyl alcohol)-bacterial cellulose nanocomposite |
JP2005097271A (ja) * | 2003-08-20 | 2005-04-14 | Matsumoto Shika Univ | 抗真菌剤用組成物 |
US20050055099A1 (en) * | 2003-09-09 | 2005-03-10 | Ku David N. | Flexible spinal disc |
US20050171604A1 (en) * | 2004-01-20 | 2005-08-04 | Alexander Michalow | Unicondylar knee implant |
JP4683843B2 (ja) * | 2004-01-29 | 2011-05-18 | 京セラ株式会社 | 人工髄核ディスクおよびその製造方法。 |
EP1713851A2 (de) * | 2004-02-04 | 2006-10-25 | Cambridge Polymer Group, Inc. | Systeme und verfahren zur regulierung und bildung von polymergelen |
US20100063174A1 (en) * | 2004-02-04 | 2010-03-11 | Ruberti Jeffrey W | Systems and methods for controlling and forming polymer gels |
WO2005077013A2 (en) | 2004-02-06 | 2005-08-25 | Georgia Tech Research Corporation | Surface directed cellular attachment |
WO2005077304A1 (en) | 2004-02-06 | 2005-08-25 | Georgia Tech Research Corporation | Load bearing biocompatible device |
US7282165B2 (en) * | 2004-04-27 | 2007-10-16 | Howmedica Osteonics Corp. | Wear resistant hydrogel for bearing applications |
US8414547B2 (en) * | 2004-04-29 | 2013-04-09 | C. R. Bard, Inc. | Modulating agents for antimicrobial coatings |
US20080063693A1 (en) * | 2004-04-29 | 2008-03-13 | Bacterin Inc. | Antimicrobial coating for inhibition of bacterial adhesion and biofilm formation |
US20050278025A1 (en) * | 2004-06-10 | 2005-12-15 | Salumedica Llc | Meniscus prosthesis |
ATE489058T1 (de) * | 2004-06-29 | 2010-12-15 | Inc Biocure | Bandscheiben-nucleus-pulposus-implantat |
WO2006017845A2 (en) * | 2004-08-11 | 2006-02-16 | California Institute Of Technology | High aspect ratio template and method for producing same |
US8075904B2 (en) * | 2004-08-11 | 2011-12-13 | California Institute Of Technology | High aspect ratio template and method for producing same for central and peripheral nerve repair |
WO2006021122A2 (de) * | 2004-08-25 | 2006-03-02 | Innogel Ag | Polyvinylalkohol gele, insbesondere in situ gelierend |
JP2008512174A (ja) * | 2004-09-10 | 2008-04-24 | スティッチング ダッチ ポリマー インスティテュート | 放射線不透過性の補綴椎間円板核 |
US20090088846A1 (en) * | 2007-04-17 | 2009-04-02 | David Myung | Hydrogel arthroplasty device |
US7235592B2 (en) * | 2004-10-12 | 2007-06-26 | Zimmer Gmbh | PVA hydrogel |
US20060093639A1 (en) * | 2004-10-29 | 2006-05-04 | Starkebaum Warren L | Method and device for destroying body tissue |
AU2006216655B2 (en) | 2005-02-23 | 2012-05-31 | Zimmer Technology, Inc. | Blend hydrogels and methods of making |
US20060200250A1 (en) * | 2005-03-04 | 2006-09-07 | Ku David N | Biocompatible implant device |
WO2006102756A1 (en) * | 2005-03-30 | 2006-10-05 | University Western Ontario | Anisotropic hydrogels |
US20060224244A1 (en) * | 2005-03-31 | 2006-10-05 | Zimmer Technology, Inc. | Hydrogel implant |
US20060235542A1 (en) * | 2005-04-15 | 2006-10-19 | Zimmer Technology, Inc. | Flexible segmented bearing implant |
JP2008542518A (ja) | 2005-06-06 | 2008-11-27 | ザ ジェネラル ホスピタル コーポレイション ディー ビー エイ マサチューセッツ ジェネラル ホスピタル | 靱性ヒドロゲル |
EP1906873A2 (de) * | 2005-07-27 | 2008-04-09 | Georgia Tech Research Corporation | Implantierbare prothetische klappe für ein gefäss |
WO2007022188A2 (en) * | 2005-08-15 | 2007-02-22 | New York Society For The Relief Of The Ruptured And Crippled Maintaining The Hospital For Special Surgery | A porous non-biodegradable hydrogel admixed with a chemoattractant for tissue replacement |
ES2340526T3 (es) * | 2005-08-26 | 2010-06-04 | Synthes Gmbh | Protesis de un balon de hidrogel para el nucleus pulposus. |
US7799087B2 (en) * | 2005-08-31 | 2010-09-21 | Zimmer Gmbh | Implant |
US20070088444A1 (en) * | 2005-10-13 | 2007-04-19 | Robert A Hodorek | Method for repairing a bone defect using a formable implant which hardens in vivo |
US7914578B2 (en) * | 2005-10-24 | 2011-03-29 | Gil Vardi | Method and apparatus for expanding tissue |
US20070098799A1 (en) * | 2005-10-28 | 2007-05-03 | Zimmer, Inc. | Mineralized Hydrogels and Methods of Making and Using Hydrogels |
EP1973498B1 (de) * | 2005-11-09 | 2014-04-23 | Zimmer GmbH | Implantat |
US8262730B2 (en) | 2005-12-07 | 2012-09-11 | Zimmer, Inc. | Methods of bonding or modifying hydrogels using irradiation |
US20070141108A1 (en) * | 2005-12-20 | 2007-06-21 | Zimmer, Inc. | Fiber-reinforced water-swellable articles |
EP1801135B1 (de) * | 2005-12-22 | 2010-09-29 | Zimmer Inc. | Perfluorcyclobutanvernetzte Hydrogele |
US8506633B2 (en) * | 2005-12-27 | 2013-08-13 | Warsaw Orthopedic, Inc. | Rehydration and restoration of intervertebral discs with polyelectrolytes |
US8801790B2 (en) * | 2005-12-27 | 2014-08-12 | Warsaw Orthopedic, Inc. | Intervertebral disc augmentation and rehydration with superabsorbent polymers |
US20070149641A1 (en) * | 2005-12-28 | 2007-06-28 | Goupil Dennis W | Injectable bone cement |
US8038920B2 (en) * | 2006-01-25 | 2011-10-18 | Carticept Medical, Inc. | Methods of producing PVA hydrogel implants and related devices |
US20070233084A1 (en) * | 2006-01-25 | 2007-10-04 | Spinemedica Corporation | Implantable spinous process prosthetic devices, including cuffs, and methods of fabricating same |
US8603171B2 (en) * | 2006-01-25 | 2013-12-10 | Mimedx Group, Inc. | Spinal disc implants with flexible keels and methods of fabricating implants |
US20070179617A1 (en) * | 2006-01-25 | 2007-08-02 | Spinemedica Corporation | Prosthetic wide range motion facets and methods of fabricating same |
US20070179607A1 (en) * | 2006-01-31 | 2007-08-02 | Zimmer Technology, Inc. | Cartilage resurfacing implant |
US20070191957A1 (en) * | 2006-02-07 | 2007-08-16 | Spinemedica Corporation | Spinal implants with cooperating suture anchors |
EP1965736A2 (de) * | 2006-02-09 | 2008-09-10 | Zimmer GmbH | Implantat |
US7520888B2 (en) * | 2006-02-14 | 2009-04-21 | Warsaw Orthopedic, Inc. | Treatment of the vertebral column |
US8110242B2 (en) * | 2006-03-24 | 2012-02-07 | Zimmer, Inc. | Methods of preparing hydrogel coatings |
WO2007125060A1 (de) * | 2006-04-28 | 2007-11-08 | Zimmer Gmbh | Implantat |
US20080073817A1 (en) * | 2006-05-12 | 2008-03-27 | Abbott Laboratories | Forming pre-made pieces of pva into specific models |
AU2007267550A1 (en) * | 2006-05-25 | 2007-12-06 | The General Hospital Corporation | Anti-cross-linking agents and methods for inhibiting cross-linking of injectable hydrogel formulations |
EP2029059A2 (de) * | 2006-05-25 | 2009-03-04 | Spinemedica Corporation | Patientenspezifische wirbelsäulenimplantate sowie entsprechende systeme und verfahren |
US8246973B2 (en) | 2006-06-21 | 2012-08-21 | Advanced Cardiovascular Systems, Inc. | Freeze-thaw method for modifying stent coating |
US20080004702A1 (en) * | 2006-06-29 | 2008-01-03 | Spinemedica Corporation | Spinal implants with cooperating anchoring sutures |
KR101454041B1 (ko) * | 2006-11-06 | 2014-10-27 | 노파르티스 아게 | 안구 장치 및 그의 제조 및 사용 방법 |
CA2668347C (en) | 2006-11-07 | 2017-06-20 | Genentech, Inc. | Tissue plasminogen activator variant uses |
US7879100B2 (en) * | 2007-01-19 | 2011-02-01 | Spinemedica, Llc | Methods and systems for forming implants with selectively exposed mesh for fixation and related implants |
CA2618125A1 (en) * | 2007-02-08 | 2008-08-08 | Zimmer, Inc. | Hydrogel proximal interphalangeal implant |
US20100210752A1 (en) | 2007-04-23 | 2010-08-19 | The General Hospital Corporation | Pva hydrogels having improved creep resistance, lubricity, and toughness |
AU2008242534A1 (en) * | 2007-04-24 | 2008-10-30 | The General Hospital Corporation | PVA-PAA hydrogels |
US8979935B2 (en) * | 2007-07-31 | 2015-03-17 | Zimmer, Inc. | Joint space interpositional prosthetic device with internal bearing surfaces |
US7731988B2 (en) * | 2007-08-03 | 2010-06-08 | Zimmer, Inc. | Multi-polymer hydrogels |
US20090043398A1 (en) * | 2007-08-09 | 2009-02-12 | Zimmer, Inc. | Method of producing gradient articles by centrifugation molding or casting |
US8062739B2 (en) * | 2007-08-31 | 2011-11-22 | Zimmer, Inc. | Hydrogels with gradient |
US7947784B2 (en) * | 2007-11-16 | 2011-05-24 | Zimmer, Inc. | Reactive compounding of hydrogels |
US8167787B2 (en) | 2008-01-03 | 2012-05-01 | Revent Medical, Inc. | Partially erodable systems for treatment of obstructive sleep apnea |
US8034362B2 (en) * | 2008-01-04 | 2011-10-11 | Zimmer, Inc. | Chemical composition of hydrogels for use as articulating surfaces |
EP2240090B1 (de) | 2008-01-25 | 2019-06-19 | The Johns Hopkins University | Biologisch abbaubare nervenführungen |
WO2009103021A1 (en) * | 2008-02-14 | 2009-08-20 | Documotion Research, Inc. | Tamper evident materials for securely carrying information |
JP2011515162A (ja) * | 2008-03-21 | 2011-05-19 | バイオミメディカ インコーポレイテッド | 水和ポリマーインプラントを骨に接着するための方法、デバイスおよび組成物 |
WO2009140197A1 (en) | 2008-05-12 | 2009-11-19 | Revent Medical, Inc. | Partially erodable systems for treatment of obstructive sleep apnea |
US9439801B2 (en) | 2012-06-29 | 2016-09-13 | Revent Medical, Inc. | Systems and methods for treatment of sleep apnea |
WO2009143646A1 (de) * | 2008-05-27 | 2009-12-03 | Innogel Ag | Nucleus ersatz basierend auf injizierbaren pva gelen |
CA2727777A1 (en) * | 2008-07-07 | 2010-01-14 | Biomimedica, Inc. | Hydrophilic interpenetrating polymer networks derived from hydrophobic polymers |
US20120209396A1 (en) | 2008-07-07 | 2012-08-16 | David Myung | Orthopedic implants having gradient polymer alloys |
US9289302B2 (en) * | 2008-07-28 | 2016-03-22 | Zimmer, Inc. | Mosaicplasty constructs |
JP5722773B2 (ja) * | 2008-08-05 | 2015-05-27 | バイオミメディカ インコーポレイテッド | ポリウレタングラフト化ヒドロゲル |
CA2675217C (en) * | 2008-08-13 | 2016-10-04 | National Research Council Of Canada | Tissue-mimicking phantom for prostate cancer brachytherapy |
US8246876B2 (en) * | 2008-08-18 | 2012-08-21 | Cook Medical Technologies Llc | Embolization particles and method for making same |
CN102149735A (zh) * | 2008-09-15 | 2011-08-10 | 玛丽亚·斯特罗姆 | 乙烯醇共聚物冷冻凝胶、乙烯醇共聚物及其制备方法和由其制得的产品 |
WO2010065951A1 (en) * | 2008-12-05 | 2010-06-10 | Cambridge Polymer Group, Inc. | Hydrolyzed hydrogels |
WO2010067378A2 (en) | 2008-12-08 | 2010-06-17 | Reliance Life Sciences Pvt. Ltd. | Hydrogel composition |
KR20110110265A (ko) * | 2008-12-29 | 2011-10-06 | 신세스 게엠바하 | 수술 부위의 보존을 위한 막 조성물의 형성 방법 및 결과적으로 얻어진 막조성물 |
US8636803B2 (en) | 2009-04-07 | 2014-01-28 | Spinal Stabilization Technologies, Llc | Percutaneous implantable nuclear prosthesis |
EP2512354A4 (de) * | 2009-12-18 | 2015-09-09 | Biomimedica Inc | Verfahren, vorrichtung und system zum schaben und formen eines gelenks |
JP2013521952A (ja) * | 2010-03-19 | 2013-06-13 | レベント メディカル インコーポレイテッド | 睡眠時無呼吸の治療システム及び方法 |
CA2793213A1 (en) | 2010-03-19 | 2011-09-22 | Revent Medical Inc. | Systems and methods for treatment of sleep apnea |
WO2011146930A2 (en) | 2010-05-21 | 2011-11-24 | Revent Medical, Inc. | Systems and methods for treatment of sleep apnea |
US9232805B2 (en) | 2010-06-29 | 2016-01-12 | Biocure, Inc. | In-situ forming hydrogel wound dressings containing antimicrobial agents |
EP2598091A4 (de) | 2010-07-26 | 2014-08-20 | Revent Medical Inc | Systeme und verfahren zur behandlung von schlafapnoe |
US8668739B2 (en) | 2010-08-20 | 2014-03-11 | Zimmer, Inc. | Unitary orthopedic implant |
AU2011293169A1 (en) | 2010-08-27 | 2013-03-21 | Biomimedica, Inc. | Hydrophobic and hydrophilic interpenetrating polymer networks derived from hydrophobic polymers and methods of preparing the same |
US8353964B2 (en) | 2010-11-04 | 2013-01-15 | Carpenter Clyde T | Anatomic total disc replacement |
US8557270B2 (en) | 2011-01-12 | 2013-10-15 | New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery | Interconnected porous non-degradable poly(vinyl) alcohol implant and method of manufacture |
WO2012098419A1 (en) | 2011-01-20 | 2012-07-26 | Centre National De La Recherche Scientifique | Device for tissue repair |
EP2757964B1 (de) | 2011-05-26 | 2016-05-04 | Cartiva, Inc. | Konisches gelenkimplantat und zugehörige instrumente |
WO2012176024A1 (en) | 2011-06-23 | 2012-12-27 | Indian Institute Of Technology Kanpur | Cryogels of pva-boronic acid containing co-polymers for cell culture |
US20130103157A1 (en) | 2011-10-03 | 2013-04-25 | Lampros Kourtis | Polymeric adhesive for anchoring compliant materials to another surface |
EP2782524B1 (de) | 2011-11-21 | 2017-12-20 | Biomimedica, Inc | Systeme zum verankern orthopädischer implantate in knochen |
JP2015510818A (ja) * | 2012-03-20 | 2015-04-13 | トラスティーズ オブ タフツ カレッジ | 薬物送達のための絹リザーバー |
EP2687188A1 (de) | 2012-07-20 | 2014-01-22 | Le Centre National De La Recherche Scientifique | Künstliche Sehne oder Band mit entlang seiner Länge veränderlicher Steifigkeit |
US9737294B2 (en) | 2013-01-28 | 2017-08-22 | Cartiva, Inc. | Method and system for orthopedic repair |
EP2948068A4 (de) | 2013-01-28 | 2016-09-28 | Cartiva Inc | Systeme und verfahren für orthopädischen reparaturen |
US9179997B2 (en) * | 2013-03-06 | 2015-11-10 | St. Jude Medical, Cardiology Division, Inc. | Thermochromic polyvinyl alcohol based hydrogel artery |
US9295479B2 (en) | 2013-03-14 | 2016-03-29 | Spinal Stabilization Technologies, Llc | Surgical device |
US20140277467A1 (en) | 2013-03-14 | 2014-09-18 | Spinal Stabilization Technologies, Llc | Prosthetic Spinal Disk Nucleus |
US10245075B2 (en) | 2013-03-15 | 2019-04-02 | Eurica Califorrniaa | Nondestructive means of ectopic pregnancy management |
JP6432860B2 (ja) * | 2013-08-30 | 2018-12-05 | 国立大学法人横浜国立大学 | ハイブリッドゲルの製造方法 |
US9561095B1 (en) | 2015-10-12 | 2017-02-07 | Phi Nguyen | Body augmentation device |
US9873769B2 (en) | 2014-07-10 | 2018-01-23 | Cambridge Polymer Group, Inc. | Thiolated PEG-PVA hydrogels |
WO2016073587A1 (en) | 2014-11-04 | 2016-05-12 | Spinal Stabilization Technologies Llc | Percutaneous implantable nuclear prosthesis |
CA2966748C (en) | 2014-11-04 | 2023-03-21 | Spinal Stabilization Technologies Llc | Percutaneous implantable nuclear prosthesis |
US10201425B2 (en) | 2015-03-02 | 2019-02-12 | Georgia Tech Research Corporation | Implantable open vein valve |
EP3892241A1 (de) | 2015-03-31 | 2021-10-13 | Cartiva, Inc. | Bohrer für karpometakarpalimplantat |
US9907663B2 (en) | 2015-03-31 | 2018-03-06 | Cartiva, Inc. | Hydrogel implants with porous materials and methods |
EP3282961A4 (de) | 2015-04-14 | 2018-12-05 | Cartiva, Inc. | Werkzeug zur erzeugung einer konischen öffnung in gewebe und zugehörige verfahren |
JP6578592B2 (ja) * | 2015-05-07 | 2019-09-25 | 国立大学法人北陸先端科学技術大学院大学 | 人工血管用ゲル材料及びその製造方法 |
US11077228B2 (en) | 2015-08-10 | 2021-08-03 | Hyalex Orthopaedics, Inc. | Interpenetrating polymer networks |
CN108348227B (zh) | 2015-09-01 | 2021-03-09 | 脊柱稳定技术有限责任公司 | 可植入的核假体 |
EP3393537B1 (de) | 2015-12-22 | 2024-05-22 | Access Vascular, Inc. | Hochfeste biomedizinische materialien |
ITUB20160702A1 (it) | 2016-02-12 | 2017-08-12 | Consiglio Nazionale Ricerche | Criogel per la rimozione di eparine ed eparinoidi da soluzioni acquose, fisiologiche e da fluidi biologici, suo processo di preparazione ed usi |
IL265812B1 (en) | 2016-10-06 | 2024-05-01 | Medicem Tech S R O | Osmotic cervical dilators combined with hydrogel |
US10653783B2 (en) * | 2016-11-09 | 2020-05-19 | Colorado School Of Mines | Sustained release of bioactive factors from zwitterionic hydrogels |
AU2018290246A1 (en) | 2017-06-21 | 2020-01-30 | Access Vascular, Inc | High strength porous materials incorporating water soluble polymers |
US10869950B2 (en) | 2018-07-17 | 2020-12-22 | Hyalex Orthopaedics, Inc. | Ionic polymer compositions |
EP3829468A4 (de) | 2018-09-04 | 2022-08-10 | Spinal Stabilization Technologies LLC | Implantierbare nuklearprothese, kits und zugehörige verfahren |
US11517141B1 (en) | 2018-09-27 | 2022-12-06 | Ripples Ltd. | Ink-printing apparatuses, methods and formulations |
EP3897765A2 (de) | 2018-12-19 | 2021-10-27 | Access Vascular, Inc. | Hochfeste poröse materialien für kontrollierte freisetzung |
CN109762182B (zh) * | 2019-01-02 | 2021-09-24 | 大连理工大学 | 一种高强度-多孔结构聚乙烯醇-单宁酸水凝胶的制备方法及应用 |
CN109998625A (zh) * | 2019-03-28 | 2019-07-12 | 浙江大学 | 一种组织夹 |
WO2022006000A1 (en) | 2020-06-30 | 2022-01-06 | Access Vascular, Inc. | Articles comprising markings and related methods |
WO2022155430A1 (en) * | 2021-01-15 | 2022-07-21 | Athena Devices, Inc. | Compositions and methods for soft tissue augmentation |
KR102590624B1 (ko) * | 2022-09-07 | 2023-10-20 | 주식회사 뉴로소나 | 초음파 음향 결합용 고형겔 제조 장치 및 방법 |
CN115624652B (zh) * | 2022-10-27 | 2024-04-09 | 青岛海洋科技中心 | 一种聚乙烯醇人工眼组织工程替代材料的制备方法及其制备的人工眼组织工程替代材料 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4734097A (en) * | 1981-09-25 | 1988-03-29 | Nippon Oil Company, Ltd. | Medical material of polyvinyl alcohol and process of making |
JPS62204740A (ja) * | 1985-11-14 | 1987-09-09 | 日石三菱株式会社 | 義歯床 |
JPS62153229A (ja) * | 1985-12-27 | 1987-07-08 | Nippon Oil Co Ltd | 皮膚マ−カ− |
US5266480A (en) * | 1986-04-18 | 1993-11-30 | Advanced Tissue Sciences, Inc. | Three-dimensional skin culture system |
JP3007903B2 (ja) | 1991-03-29 | 2000-02-14 | 京セラ株式会社 | 人工椎間板 |
US5258042A (en) | 1991-12-16 | 1993-11-02 | Henry Ford Health System | Intravascular hydrogel implant |
US5260066A (en) * | 1992-01-16 | 1993-11-09 | Srchem Incorporated | Cryogel bandage containing therapeutic agent |
US5258032A (en) | 1992-04-03 | 1993-11-02 | Bertin Kim C | Knee prosthesis provisional apparatus and resection guide and method of use in knee replacement surgery |
US5343877A (en) * | 1992-09-09 | 1994-09-06 | University Of Iowa Research Foundation | Orthopedic implant and method |
US5326364A (en) | 1992-12-16 | 1994-07-05 | Wright Medical Technology, Inc. | Trapezial implant |
US5556429A (en) | 1994-05-06 | 1996-09-17 | Advanced Bio Surfaces, Inc. | Joint resurfacing system |
US5700289A (en) * | 1995-10-20 | 1997-12-23 | North Shore University Hospital Research Corporation | Tissue-engineered bone repair using cultured periosteal cells |
US5847046A (en) * | 1997-03-12 | 1998-12-08 | United States Surgical Corporation | Biodegradable bone cement |
-
1997
- 1997-09-17 US US08/932,029 patent/US5981826A/en not_active Expired - Lifetime
-
1998
- 1998-05-05 DE DE69828050T patent/DE69828050T2/de not_active Expired - Lifetime
- 1998-05-05 WO PCT/US1998/009129 patent/WO1998050017A1/en active IP Right Grant
- 1998-05-05 ES ES98918953T patent/ES2232945T3/es not_active Expired - Lifetime
- 1998-05-05 EP EP98918953A patent/EP0991402B1/de not_active Expired - Lifetime
- 1998-05-05 EP EP04012443A patent/EP1468676A3/de not_active Withdrawn
- 1998-05-05 DK DK98918953T patent/DK0991402T3/da active
- 1998-05-05 CA CA002288793A patent/CA2288793C/en not_active Expired - Fee Related
- 1998-05-05 AT AT98918953T patent/ATE284203T1/de not_active IP Right Cessation
- 1998-05-05 PT PT98918953T patent/PT991402E/pt unknown
- 1998-05-05 AU AU71766/98A patent/AU728426B2/en not_active Ceased
- 1998-05-05 JP JP54838198A patent/JP3506718B2/ja not_active Expired - Lifetime
-
1999
- 1999-03-17 US US09/271,032 patent/US6231605B1/en not_active Expired - Lifetime
-
2001
- 2001-05-01 US US09/846,788 patent/US20010029399A1/en not_active Abandoned
-
2002
- 2002-07-22 JP JP2002212822A patent/JP3971260B2/ja not_active Expired - Lifetime
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EP0991402A1 (de) | 2000-04-12 |
ES2232945T3 (es) | 2005-06-01 |
DE69828050T2 (de) | 2005-12-01 |
EP0991402B1 (de) | 2004-12-08 |
EP1468676A2 (de) | 2004-10-20 |
AU7176698A (en) | 1998-11-27 |
US6231605B1 (en) | 2001-05-15 |
EP0991402A4 (de) | 2001-08-22 |
EP1468676A3 (de) | 2008-04-09 |
WO1998050017A1 (en) | 1998-11-12 |
AU728426B2 (en) | 2001-01-11 |
DK0991402T3 (da) | 2005-03-29 |
CA2288793C (en) | 2006-02-14 |
CA2288793A1 (en) | 1998-11-12 |
US20010029399A1 (en) | 2001-10-11 |
US5981826A (en) | 1999-11-09 |
PT991402E (pt) | 2005-02-28 |
DE69828050D1 (de) | 2005-01-13 |
JP3971260B2 (ja) | 2007-09-05 |
JP2003038637A (ja) | 2003-02-12 |
JP3506718B2 (ja) | 2004-03-15 |
JP2001508690A (ja) | 2001-07-03 |
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