ATE277935T1 - Auf lipiden basierende systeme zur arzneistoffabgabe - Google Patents

Auf lipiden basierende systeme zur arzneistoffabgabe

Info

Publication number
ATE277935T1
ATE277935T1 AT01903609T AT01903609T ATE277935T1 AT E277935 T1 ATE277935 T1 AT E277935T1 AT 01903609 T AT01903609 T AT 01903609T AT 01903609 T AT01903609 T AT 01903609T AT E277935 T1 ATE277935 T1 AT E277935T1
Authority
AT
Austria
Prior art keywords
drug delivery
based drug
lipide
delivery systems
carbon atoms
Prior art date
Application number
AT01903609T
Other languages
German (de)
English (en)
Inventor
Kent Joergensen
Jesper Davidsen
Charlotte Vermehren
Sven Froekjaer
Ole G Mouritsen
Original Assignee
Liplasome Pharma As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Liplasome Pharma As filed Critical Liplasome Pharma As
Application granted granted Critical
Publication of ATE277935T1 publication Critical patent/ATE277935T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT01903609T 2000-02-10 2001-02-09 Auf lipiden basierende systeme zur arzneistoffabgabe ATE277935T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200000211 2000-02-10
DKPA200000616 2000-04-12
PCT/DK2001/000092 WO2001058910A2 (en) 2000-02-10 2001-02-09 Lipid-based drug delivery systems

Publications (1)

Publication Number Publication Date
ATE277935T1 true ATE277935T1 (de) 2004-10-15

Family

ID=26068763

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01903609T ATE277935T1 (de) 2000-02-10 2001-02-09 Auf lipiden basierende systeme zur arzneistoffabgabe

Country Status (9)

Country Link
EP (2) EP1254143B1 (enExample)
JP (1) JP2003522193A (enExample)
AT (1) ATE277935T1 (enExample)
AU (1) AU778659B2 (enExample)
CA (1) CA2399821A1 (enExample)
DE (1) DE60105977T2 (enExample)
ES (1) ES2230268T3 (enExample)
PT (1) PT1254143E (enExample)
WO (1) WO2001058910A2 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003028696A2 (en) * 2001-10-03 2003-04-10 Celator Technologies Inc. Compositions for delivery of drug combinations
CA2383259A1 (en) 2002-04-23 2003-10-23 Celator Technologies Inc. Synergistic compositions
US7850990B2 (en) 2001-10-03 2010-12-14 Celator Pharmaceuticals, Inc. Compositions for delivery of drug combinations
JP2008518886A (ja) * 2004-11-03 2008-06-05 リプラサム ファーマ アー／エス 非天然ホスホリパーゼａ２分解性脂質誘導体を含有する脂質ベースの薬剤送達系およびその治療的使用
WO2006086992A2 (en) * 2005-02-18 2006-08-24 Liplasome Pharma A/S Drug delivery systems containing phqspholipase a2 degradable lipid prodrug derivatives and the therapeutic uses thereof as. e.g. wound healing agents and peroxisome proliferator activated receptor ligands
US8137693B2 (en) 2005-09-30 2012-03-20 Auburn University Drug delivery nanocarriers targeted by landscape phage
AU2007229160A1 (en) * 2006-03-23 2007-09-27 Liplasome Pharma A/S Lipid based drug delivery systems comprising phospholipase A2 degradable lipids that perform an intramolecular cyclization reaction upon hydrolysis
EP2123258A1 (en) * 2008-05-23 2009-11-25 Liplasome Pharma A/S Liposomes for drug delivery
DK177532B1 (en) 2009-09-17 2013-09-08 Bio Bedst Aps Medical use of sPLA2 hydrolysable liposomes
DK177529B1 (en) * 2009-10-23 2013-09-08 Bio Bedst Aps Liposomes with improved storage stability
EP2343310A1 (en) 2010-01-08 2011-07-13 Novozymes A/S Serine hydrolase formulation
WO2011098578A2 (en) 2010-02-12 2011-08-18 Bioneer A/S Liposome system for ocular administration
CZ308596B6 (cs) * 2017-04-03 2020-12-23 Ústav molekulární genetiky AV ČR, v. v. i. Deriváty fosfolipidů a jejich použití jako léčiva
EP3530266A1 (en) * 2018-02-27 2019-08-28 LipoCoat B.V. A lipid-based coating composition, and an object having a lipid-based coating
EP3530265A1 (en) * 2018-02-27 2019-08-28 LipoCoat B.V. Universal method for the preparation of lipid-based coatings

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4622392A (en) * 1984-06-21 1986-11-11 Health Research Inc. (Roswell Park Division) Thiophospholipid conjugates of antitumor agents
US5153000A (en) * 1988-11-22 1992-10-06 Kao Corporation Phosphate, liposome comprising the phosphate as membrane constituent, and cosmetic and liposome preparation comprising the liposome
JPH07126166A (ja) * 1993-10-29 1995-05-16 Sagami Chem Res Center ホスホリパ−ゼａ２阻害剤
JP3498336B2 (ja) * 1993-12-06 2004-02-16 日本油脂株式会社 リン脂質誘導体
JP3620059B2 (ja) * 1994-03-04 2005-02-16 日本油脂株式会社 反応性小胞体、形成剤および機能性物質固定化小胞体
DE4408011C1 (de) * 1994-03-10 1995-11-02 Max Delbrueck Centrum Pharmazeutisches Mittel zur Tumortherapie
US5817856A (en) * 1995-12-11 1998-10-06 Yissum Research Development Company Of The Hebrew University Of Jerusalem Radiation-protective phospholipid and method
JP3778528B2 (ja) * 1996-11-08 2006-05-24 三菱化学株式会社 ミセルに組み込まれた水溶性高分子物質の分析方法
US5827836A (en) * 1996-11-15 1998-10-27 Clarion Pharmaceuticals Inc. Retinoid glycerol phospholipid conjugates
US6200598B1 (en) * 1998-06-18 2001-03-13 Duke University Temperature-sensitive liposomal formulation

Also Published As

Publication number Publication date
DE60105977D1 (de) 2004-11-04
EP1484332A2 (en) 2004-12-08
AU3153301A (en) 2001-08-20
PT1254143E (pt) 2005-02-28
DE60105977T2 (de) 2006-02-23
JP2003522193A (ja) 2003-07-22
EP1254143A2 (en) 2002-11-06
ES2230268T3 (es) 2005-05-01
AU778659B2 (en) 2004-12-16
WO2001058910A3 (en) 2002-02-21
WO2001058910A2 (en) 2001-08-16
EP1254143B1 (en) 2004-09-29
EP1484332A3 (en) 2009-01-21
CA2399821A1 (en) 2001-08-16

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