ATE277634T1 - Assembly-defizientes herpesvirus als impfstoff - Google Patents

Assembly-defizientes herpesvirus als impfstoff

Info

Publication number
ATE277634T1
ATE277634T1 AT97937214T AT97937214T ATE277634T1 AT E277634 T1 ATE277634 T1 AT E277634T1 AT 97937214 T AT97937214 T AT 97937214T AT 97937214 T AT97937214 T AT 97937214T AT E277634 T1 ATE277634 T1 AT E277634T1
Authority
AT
Austria
Prior art keywords
assembly
vaccine
deficiency
herpes virus
herpesvirus
Prior art date
Application number
AT97937214T
Other languages
English (en)
Inventor
Paul J Hippenmeyer
Anne M Rankin
Verne A Luckow
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Application granted granted Critical
Publication of ATE277634T1 publication Critical patent/ATE277634T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/245—Herpetoviridae, e.g. herpes simplex virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/503—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Mycology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
AT97937214T 1996-07-26 1997-07-25 Assembly-defizientes herpesvirus als impfstoff ATE277634T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/687,820 US5972666A (en) 1996-07-26 1996-07-26 Assembly-deficient herpesvirus vaccine
PCT/US1997/014192 WO1998004286A2 (en) 1996-07-26 1997-07-25 Assembly-deficient herpesvirus vaccine

Publications (1)

Publication Number Publication Date
ATE277634T1 true ATE277634T1 (de) 2004-10-15

Family

ID=24761993

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97937214T ATE277634T1 (de) 1996-07-26 1997-07-25 Assembly-defizientes herpesvirus als impfstoff

Country Status (14)

Country Link
US (1) US5972666A (de)
EP (1) EP0956045B1 (de)
JP (1) JP2000516597A (de)
CN (1) CN1230893A (de)
AT (1) ATE277634T1 (de)
AU (1) AU3977997A (de)
BR (1) BR9710604A (de)
CA (1) CA2261071A1 (de)
CZ (1) CZ17999A3 (de)
DE (1) DE69730993T2 (de)
DK (1) DK0956045T3 (de)
ES (1) ES2231884T3 (de)
PT (1) PT956045E (de)
WO (1) WO1998004286A2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE50012015D1 (de) * 1999-02-04 2006-03-30 Joern Bullerdiek Mittel zur prävention und/oder behandlung einer gewebeveränderung mesenchymalen ursprungs
US6291226B1 (en) * 1999-02-25 2001-09-18 National Research Council Of Canada Adenovirus mutants with deleted protease gene
HUP0202738A3 (en) * 1999-09-10 2003-12-29 Akzo Nobel Nv Equine herpes virus temperature sensitive mutant and live vaccine thereof
WO2001078776A1 (en) * 2000-04-13 2001-10-25 Avant Immunotherapeutics, Inc. Herpes virus complementing cell line
AU2002305914A1 (en) * 2001-01-12 2002-10-21 Chiron Corporation Nucleic acid mucosal immunization
US7968298B2 (en) * 2001-03-28 2011-06-28 The United States Of America As Represented By The Department Of Health And Human Services Use of herpesviruses, herpesvirus proteins and nucleic acids encoding the proteins to inhibit CCR5-tropic HIV-1 infection and replication
WO2005021746A1 (ja) * 2003-08-29 2005-03-10 Virus Ikagaku Kenkyusho Inc. Ｈｈｖ−６またはｈｈｖ−７由来の組換ウイルスベクター、その製造方法、それを用いた宿主細胞の形質転換方法、それにより形質転換された宿主細胞およびそれを用いた遺伝子治療方法
US20080089910A1 (en) * 2004-06-29 2008-04-17 Visalli Et Al Attenuated Herpes Simplex Virus Type-2, Vectors Thereof and Immunogenic Compositions Thereof
US7628993B2 (en) 2006-07-20 2009-12-08 Vical Incorporated Compositions and methods for vaccinating against HSV-2
CN111117974B (zh) * 2019-12-20 2022-02-22 华南农业大学 一种可视化绿色荧光猪伪狂犬病毒及其构建方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9102126D0 (en) * 1991-01-31 1991-03-13 Smithkline Beecham Biolog Novel vaccine
JPH05236967A (ja) * 1991-05-07 1993-09-17 Medical Res Council ヘルペスウイルス粒子及びワクチン
WO1996012007A1 (en) * 1994-10-17 1996-04-25 Merck & Co., Inc. Stable recombinant hcmv protease
US5728557A (en) * 1995-06-01 1998-03-17 Merck & Co., Inc. Method of making herpes simplex type 1 mutants and mutants so produced

Also Published As

Publication number Publication date
BR9710604A (pt) 1999-08-17
EP0956045A2 (de) 1999-11-17
CN1230893A (zh) 1999-10-06
EP0956045B1 (de) 2004-09-29
DE69730993T2 (de) 2005-10-06
CZ17999A3 (cs) 1999-07-14
US5972666A (en) 1999-10-26
DK0956045T3 (da) 2005-01-24
WO1998004286A2 (en) 1998-02-05
CA2261071A1 (en) 1998-02-05
PT956045E (pt) 2005-01-31
ES2231884T3 (es) 2005-05-16
JP2000516597A (ja) 2000-12-12
WO1998004286A3 (en) 1998-05-14
AU3977997A (en) 1998-02-20
DE69730993D1 (de) 2004-11-04

Similar Documents

Publication Publication Date Title
ATE277634T1 (de) Assembly-defizientes herpesvirus als impfstoff
GB2263480A (en) Viral defective vaccine produced by transcomplementing cell line
AU6489986A (en) Thymidine kinase deletion mutants of bovine herpersvirus-1, vaccines against infectious bovine rhinotracheitis containing same and methods for the production and use of same
DE69535018D1 (de) Papillomavirus vakzine
DE3268361D1 (en) New vaccine and therapy against non-a non-b viral hepatitis, and their preparation process
ATE228008T1 (de) Herpesvirus impfstoffe
SE7504221L (sv) Cellvirusvaccin och forfarande for framstellning av vaccinet.
CA2417923A1 (en) Vaccination against host cell-associated herpesviruses
ATE360061T1 (de) Replikationsmangelhafte mutanten von herpesvirus
AR004464A1 (es) Un metodo para producir una proteina de capside de papilomavirus
DE69533067D1 (de) Hepatis e-virus antigene und dessen verwendungen
AU2403188A (en) Infectious bovine rhinotracheitis virus mutants, vaccines containing same, methods for the production of same and methods for the use of same
ATE248604T1 (de) Avirulente herpetische viren verwendbar als tumorzerstörendes agens und impfstoff
CA2116355A1 (en) Infectious bovine rhinotracheitis virus mutants and vaccines
CA2108292A1 (en) Process for preparing hepatitis a (hav) antigens and vaccines
WO1996001615A3 (en) Hepatitis a virus deletion mutants and vaccine formulations containing the same
ATE228568T1 (de) Herpesvirus-partikel zubereitung und vakzine
WO2000058444A3 (en) Adaptation of virus to vertebrate cells
ES2074965A1 (es) Virus mutante recombinante de rinotraqueitis infecciosa bovina y vacunas que lo contienen.
DE3779444D1 (de) Impfstoff gegen herpes simplex.
ATE46264T1 (de) Thymidinkinase-negativ-temperaturbestaendiger rinder herpes-virus-1-mutant als vakzin gegen infektioese rinder-rhinotracheitis.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0956045

Country of ref document: EP

REN Ceased due to non-payment of the annual fee