ATE248604T1 - Avirulente herpetische viren verwendbar als tumorzerstörendes agens und impfstoff - Google Patents
Avirulente herpetische viren verwendbar als tumorzerstörendes agens und impfstoffInfo
- Publication number
- ATE248604T1 ATE248604T1 AT96927257T AT96927257T ATE248604T1 AT E248604 T1 ATE248604 T1 AT E248604T1 AT 96927257 T AT96927257 T AT 96927257T AT 96927257 T AT96927257 T AT 96927257T AT E248604 T1 ATE248604 T1 AT E248604T1
- Authority
- AT
- Austria
- Prior art keywords
- viruses
- neoplastic cells
- herpetic
- avirulent
- tumoricidal
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16621—Viruses as such, e.g. new isolates, mutants or their genomic sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16632—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Mycology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US160295P | 1995-07-27 | 1995-07-27 | |
PCT/US1996/012281 WO1997004804A1 (en) | 1995-07-27 | 1996-07-25 | Avirulent herpetic viruses useful as tumoricidal agents and vaccines |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE248604T1 true ATE248604T1 (de) | 2003-09-15 |
Family
ID=21696918
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT96927257T ATE248604T1 (de) | 1995-07-27 | 1996-07-25 | Avirulente herpetische viren verwendbar als tumorzerstörendes agens und impfstoff |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP0841943B1 (de) |
AT (1) | ATE248604T1 (de) |
AU (1) | AU725557B2 (de) |
CA (1) | CA2227860C (de) |
DE (1) | DE69629819T2 (de) |
DK (1) | DK0841943T3 (de) |
ES (1) | ES2205053T3 (de) |
IL (1) | IL118942A (de) |
WO (1) | WO1997004804A1 (de) |
ZA (1) | ZA966287B (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9704046D0 (en) * | 1997-02-27 | 1997-04-16 | Univ Leeds | Arrestable therapeutic |
KR100701905B1 (ko) * | 1999-08-31 | 2007-04-02 | 더 제너럴 호스피탈 코포레이션 | 헤르페스 감마 34.5 유전자 발현을 재표적화하는 세포특이적 및/또는 종양 특이적 프로모터 |
US6897057B1 (en) | 1999-08-31 | 2005-05-24 | The General Hospital Corporation | Cell-specific and/or tumor-specific promoter retargeting of herpes γ 34.5 gene expression |
CA2398335C (en) | 2000-01-21 | 2010-12-07 | Biovex Limited | Herpes virus strains |
CA2352439A1 (en) * | 2001-07-17 | 2003-01-17 | Patrick W. K. Lee | Engineering oncolytic viruses |
GB0317511D0 (en) | 2003-07-25 | 2003-08-27 | Biovex Ltd | Viral vectors |
JP2007511216A (ja) | 2003-11-17 | 2007-05-10 | クルセイド ラボラトリーズ リミテッド | 変異ウイルス |
US7897146B2 (en) | 2003-11-17 | 2011-03-01 | Crusade Laboratories Limited | Treatment using herpes simplex virus |
GB0326798D0 (en) | 2003-11-17 | 2003-12-24 | Crusade Lab Ltd | Methods for generating mutant virus |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5328688A (en) * | 1990-09-10 | 1994-07-12 | Arch Development Corporation | Recombinant herpes simplex viruses vaccines and methods |
CA2051289C (en) * | 1990-09-14 | 2002-11-26 | Robert L. Martuza | Viral mediated destruction of neoplastic cells |
US5585096A (en) * | 1994-06-23 | 1996-12-17 | Georgetown University | Replication-competent herpes simplex virus mediates destruction of neoplastic cells |
GB9415320D0 (en) * | 1994-07-29 | 1994-09-21 | Medical Res Council | Cancer treatment |
-
1996
- 1996-07-24 IL IL11894296A patent/IL118942A/en not_active IP Right Cessation
- 1996-07-24 ZA ZA9606287A patent/ZA966287B/xx unknown
- 1996-07-25 EP EP96927257A patent/EP0841943B1/de not_active Expired - Lifetime
- 1996-07-25 WO PCT/US1996/012281 patent/WO1997004804A1/en active IP Right Grant
- 1996-07-25 CA CA2227860A patent/CA2227860C/en not_active Expired - Lifetime
- 1996-07-25 DE DE69629819T patent/DE69629819T2/de not_active Expired - Lifetime
- 1996-07-25 AU AU67139/96A patent/AU725557B2/en not_active Expired
- 1996-07-25 ES ES96927257T patent/ES2205053T3/es not_active Expired - Lifetime
- 1996-07-25 DK DK96927257T patent/DK0841943T3/da active
- 1996-07-25 AT AT96927257T patent/ATE248604T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA2227860C (en) | 2011-05-24 |
IL118942A0 (en) | 1996-10-31 |
EP0841943A1 (de) | 1998-05-20 |
DK0841943T3 (da) | 2003-12-08 |
EP0841943B1 (de) | 2003-09-03 |
CA2227860A1 (en) | 1997-02-13 |
ES2205053T3 (es) | 2004-05-01 |
ZA966287B (en) | 1998-03-09 |
AU6713996A (en) | 1997-02-26 |
WO1997004804A1 (en) | 1997-02-13 |
DE69629819T2 (de) | 2004-05-06 |
AU725557B2 (en) | 2000-10-12 |
IL118942A (en) | 2002-09-12 |
DE69629819D1 (de) | 2003-10-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Fields et al. | Genetic and molecular mechanisms of viral pathogenesis: implications for prevention and treatment | |
LU93100I2 (fr) | Talimogene laherparepvec et ses dérivés pharmaceutiquement acceptables (imlygic) | |
Sabin et al. | Behavior of noninfectious SV 40 viral genome in hamster tumor cells: induction of synthesis of infectious virus | |
DK0500917T3 (da) | Vacciner og fremgangsmåder baseret på rekombinante herpes simplex virusser. | |
ES8505719A1 (es) | Procedimiento de preparar mutantes de delecion vivos y metodo de preparar vacunas | |
ATE73348T1 (de) | Thymidinkinase-deletionsmutanten von bovinem herpesvirus-1, diese enthaltende impfstoffe gegen bovine rhinotracheitis und verfahren zu deren herstellung und verwendung. | |
ES2074950A1 (es) | Vacuna para la prevencion de la enfermedad reproductiva y respiratoria de la cerda. | |
DE69121452D1 (de) | Gen-Sequenzentransfer und -exprimierung bei Zellen des zentralen Nervensystems mit mutierenden Herpes-Simplex-Viren, die Deletionen in Viren-Replikationsgenen enthalten | |
NO20091761L (no) | Viruskapsomervaksine, fremgangsmate for fremstilling samt anvendelse derav | |
JP2003520044A5 (de) | ||
WO1994021807A3 (en) | Defective mutant non-retroviral virus (e.g. hsv) as vaccine | |
ATE248604T1 (de) | Avirulente herpetische viren verwendbar als tumorzerstörendes agens und impfstoff | |
NZ315357A (en) | Method for industrially producing a japanese encephalitis vaccine, and resulting vaccine | |
CA2073288A1 (en) | Manipulation of gene copy number in bordetella | |
BR9711998A (pt) | Herpesvìrus saimiri como vetor viral. | |
Vahlne et al. | Herpes simplex virus infection of mouse neuroblastoma cells | |
EP0326127A3 (de) | Infektiöse Rinder-Rhinotracheitis-Virus-Insertionsmutanten, sie enthaltende Impfstoffe, Verfahren zu ihrer Herstellung und ihre Verwendung | |
ATE277634T1 (de) | Assembly-defizientes herpesvirus als impfstoff | |
WO1994000586A3 (fr) | Mutants et vaccins du virus de la rhinotracheite infectieuse bovine | |
Agol et al. | Modification of translational control elements as a new approach to design of attenuated picornavirus strains | |
Gruss et al. | Infectious linear DNA sequences replicating in simian virus 40-infected cells | |
Fenner | Interactions between pox viruses | |
Hradečná | X-ray Inactivation of Lambda Phage: II. Reactivation Processes | |
Detsch et al. | Ultraviolet enhanced reactivation of Herpes simplex virus inactivated by different wavelengths of UV radiation | |
TH45960EX (th) | วัคซีนต่อต้านโรคพิษสุนัขบ้าที่ไม่ทำให้เกิดโรค |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 0841943 Country of ref document: EP |
|
REN | Ceased due to non-payment of the annual fee |