ATE275394T1 - R- und s- enantiomere getrennteteile enthaltende dosierungsformen - Google Patents

R- und s- enantiomere getrennteteile enthaltende dosierungsformen

Info

Publication number
ATE275394T1
ATE275394T1 AT98910863T AT98910863T ATE275394T1 AT E275394 T1 ATE275394 T1 AT E275394T1 AT 98910863 T AT98910863 T AT 98910863T AT 98910863 T AT98910863 T AT 98910863T AT E275394 T1 ATE275394 T1 AT E275394T1
Authority
AT
Austria
Prior art keywords
enantiomeric
dosage forms
dosage form
separate parts
enantiomers
Prior art date
Application number
AT98910863T
Other languages
German (de)
English (en)
Inventor
Julian Clive Gilbert
Andrew J M Richards
Hazel Judith Bardsley
Original Assignee
Arakis Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9704978.7A external-priority patent/GB9704978D0/en
Priority claimed from GBGB9719261.1A external-priority patent/GB9719261D0/en
Application filed by Arakis Ltd filed Critical Arakis Ltd
Application granted granted Critical
Publication of ATE275394T1 publication Critical patent/ATE275394T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
AT98910863T 1997-03-11 1998-03-11 R- und s- enantiomere getrennteteile enthaltende dosierungsformen ATE275394T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9704978.7A GB9704978D0 (en) 1997-03-11 1997-03-11 Dosage forms
GBGB9719261.1A GB9719261D0 (en) 1997-09-10 1997-09-10 Dosage forms
PCT/GB1998/000726 WO1998040053A1 (en) 1997-03-11 1998-03-11 Dosage forms comprising separate portions of r- and s-enantiomers
US09/038,873 US6056968A (en) 1997-03-11 1998-03-11 Pharmaceutical drug dosage forms providing different release rates

Publications (1)

Publication Number Publication Date
ATE275394T1 true ATE275394T1 (de) 2004-09-15

Family

ID=27268767

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98910863T ATE275394T1 (de) 1997-03-11 1998-03-11 R- und s- enantiomere getrennteteile enthaltende dosierungsformen

Country Status (15)

Country Link
US (2) US6056968A (https=)
EP (1) EP0969818B1 (https=)
JP (1) JP2001514651A (https=)
CN (1) CN1251987A (https=)
AT (1) ATE275394T1 (https=)
AU (1) AU741821B2 (https=)
BR (1) BR9808325A (https=)
CA (1) CA2285407C (https=)
DE (1) DE69826113T2 (https=)
ES (1) ES2227814T3 (https=)
HU (1) HUP0000759A3 (https=)
IL (1) IL131713A (https=)
NO (1) NO994412L (https=)
PL (1) PL335619A1 (https=)
WO (1) WO1998040053A1 (https=)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5912268A (en) * 1995-05-22 1999-06-15 Alza Corporation Dosage form and method for treating incontinence
US6262115B1 (en) * 1995-05-22 2001-07-17 Alza Coporation Method for the management of incontinence
HUP0104420A2 (en) * 1998-12-02 2002-08-28 Darwin Discovery Ltd Therapeutic composition containing a new form of tramadol and its use
AU3064800A (en) * 1999-01-21 2000-08-07 Darwin Discovery Limited The therapeutic use of r-warfarin as anticoagulant
US20030170181A1 (en) * 1999-04-06 2003-09-11 Midha Kamal K. Method for preventing abuse of methylphenidate
PE20010623A1 (es) * 1999-10-05 2001-07-07 Gruenenthal Chemie Uso de (+)-tramadol y/o o-demetiltramadol para tratamiento de urgencia urinaria incrementada y/o incontinencia urinaria
EP1313460A2 (en) * 1999-11-09 2003-05-28 Darwin Discovery Limited Therapeutic use and formulation of (-)-tramadol
DE10004926A1 (de) 2000-02-04 2001-08-09 Gruenenthal Gmbh Verfahren zur enzymatischen Racematspaltung von Aminomethyl-Aryl-Cyclohexanol-Derivaten
AU3582101A (en) 2000-03-01 2001-09-12 Euro-Celtique S.A. The treatment of functional gastrointestinal disorders
US20010036959A1 (en) * 2000-04-03 2001-11-01 Gabel Rolf Dieter Carvedilol-hydrophilic solutions
CA2423558A1 (en) * 2000-10-03 2002-04-11 Penwest Pharmaceuticals Company Delivery system for multi-pharmaceutical active materials at various release rates
WO2002065834A2 (en) * 2000-10-24 2002-08-29 Smithkline Beecham Corporation Novel formulations of carvedilol
US6562871B1 (en) * 2000-11-06 2003-05-13 Boehringer Ingelheim Pharmaceuticals, Inc. Dry granulation of pharmaceutical formulation comprising mexiletine
DE10108122A1 (de) * 2001-02-21 2002-10-02 Gruenenthal Gmbh Arzneimittel auf Basis von Tramadol
IN191028B (https=) * 2001-05-17 2003-09-13 Sun Pharmaceutical Ind Ltd
US8101209B2 (en) * 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
WO2003048113A1 (en) 2001-11-30 2003-06-12 Sepracor Inc. Tramadol analogs and uses thereof
US8128957B1 (en) 2002-02-21 2012-03-06 Valeant International (Barbados) Srl Modified release compositions of at least one form of tramadol
US20050182056A9 (en) * 2002-02-21 2005-08-18 Seth Pawan Modified release formulations of at least one form of tramadol
EP1562552A1 (en) * 2002-11-08 2005-08-17 Egalet A/S Controlled release carvedilol compositions
WO2004056336A2 (en) * 2002-12-20 2004-07-08 Ranbaxy Laboratories Limited Controlled release, multiple unit drug delivery systems
WO2004071501A1 (en) * 2003-02-10 2004-08-26 Shire Biochem Inc. Enantiomeric amphetamine compositions for the treatment of adhd
WO2004103361A2 (en) * 2003-05-20 2004-12-02 Ranbaxy Laboratories Limited A pharmaceutical dosage form of citalopram
US8263126B2 (en) * 2003-06-06 2012-09-11 Ethypharm Orally-dispersible multilayer tablet
US20060172006A1 (en) * 2003-10-10 2006-08-03 Vincent Lenaerts Sustained-release tramadol formulations with 24-hour clinical efficacy
US20050143350A1 (en) * 2003-11-19 2005-06-30 Seed John C. Combination drug therapy to treat obesity
CA2547137A1 (en) * 2003-11-25 2005-06-09 Sb Pharmco Puerto Rico Inc. Carvedilol free base, salts, anhydrous forms or solvates thereof, corresponding pharmaceutical compositions, controlled release formulations, and treatment or delivery methods
EP1686967A4 (en) * 2003-11-25 2012-08-08 Smithkline Beecham Cork Ltd CARVEDILOL-FREE BASE, SALTS, WATER-FREE FORMS OR SOLVATES THEREOF, CORRESPONDING PHARMACEUTICAL COMPOSITIONS, CONTROLLED RELEASE FORMULAS AND TREATMENT OR DISPOSAL PROCEDURES
AU2005284908B2 (en) 2004-09-13 2011-12-08 Morningside Venture Investments Limited Biosynchronous transdermal drug delivery
AU2005290829B2 (en) * 2004-10-01 2011-06-09 Nippon Zoki Pharmaceutical Co., Ltd. Solid pharmaceutical preparation
WO2007048219A2 (en) 2005-09-09 2007-05-03 Labopharm Inc. Sustained drug release composition
EP1976488A4 (en) * 2006-01-12 2010-02-10 Wockhardt Ltd ALFUZOSIN PROLONGED RELEASE PREPARATIONS
JP5120652B2 (ja) * 2006-03-30 2013-01-16 日本臓器製薬株式会社 固形医薬製剤
CN101674728A (zh) 2007-02-12 2010-03-17 Dmi生物科学公司 降低曲马多的副作用
CA2677690C (en) * 2007-02-12 2012-05-15 James V. Winkler Treatment of comorbid premature ejaculation and erectile dysfunction
CN103977003A (zh) 2007-04-02 2014-08-13 帕金森氏病研究院 用于降低治疗的副作用的方法和组合物
AU2016211330A1 (en) 2015-01-28 2017-08-03 Chrono Therapeutics Inc. Drug delivery methods and systems
CA3049529A1 (en) 2017-01-06 2018-07-12 Chrono Therapeutics Inc. Transdermal drug delivery devices and methods
US11596779B2 (en) 2018-05-29 2023-03-07 Morningside Venture Investments Limited Drug delivery methods and systems
US12397141B2 (en) 2018-11-16 2025-08-26 Morningside Venture Investments Limited Thermally regulated transdermal drug delivery system

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4818541A (en) * 1987-08-19 1989-04-04 Schering Corporation Transdermal delivery of enantiomers of phenylpropanolamine
US5145866A (en) * 1991-04-22 1992-09-08 Hoechst-Roussel Pharmaceuticals Incorporated Method of treating anxiety with the aid of r(+)-3-amino-1-hydroxy-pyrrolidin-2-one
US5204116A (en) * 1991-05-01 1993-04-20 Alza Corporation Dosage form providing immediate therapy followed by prolonged therapy
NZ260408A (en) * 1993-05-10 1996-05-28 Euro Celtique Sa Controlled release preparation comprising tramadol
DE4319438C1 (de) * 1993-06-11 1994-06-01 Gerd Dr Dr Geislinger Arzneimittel auf der Grundlage von Ketoprofen zur Bekämpfung von Schmerzen und/oder Entzündungen und/oder Fieber an Menschen und Tieren
GB9412689D0 (en) * 1994-06-23 1994-08-10 Chiroscience Ltd Cytotoxic agent and its use

Also Published As

Publication number Publication date
IL131713A (en) 2004-08-31
NO994412D0 (no) 1999-09-10
BR9808325A (pt) 2000-05-16
US6221394B1 (en) 2001-04-24
AU6508998A (en) 1998-09-29
IL131713A0 (en) 2001-03-19
AU741821B2 (en) 2001-12-13
NO994412L (no) 1999-10-20
CN1251987A (zh) 2000-05-03
DE69826113T2 (de) 2005-01-20
PL335619A1 (en) 2000-05-08
US6056968A (en) 2000-05-02
ES2227814T3 (es) 2005-04-01
HUP0000759A3 (en) 2000-11-28
HUP0000759A2 (hu) 2000-10-28
EP0969818A1 (en) 2000-01-12
DE69826113D1 (de) 2004-10-14
CA2285407A1 (en) 1998-09-17
CA2285407C (en) 2006-08-01
WO1998040053A1 (en) 1998-09-17
EP0969818B1 (en) 2004-09-08
JP2001514651A (ja) 2001-09-11

Similar Documents

Publication Publication Date Title
ATE275394T1 (de) R- und s- enantiomere getrennteteile enthaltende dosierungsformen
ZA200405029B (en) 17α-Alkyl-17β-oxy-estratrienes and intermediates for the production thereof, and use of said 17α-alkyl-17β-oxy-estratrienes for producing medicaments and pharmaceutical preparations
DK1414816T3 (da) Stabil polymorf af flibanserin, teknisk fremgangsmåde til fremstilling deraf og anvendelse deraf til lægemiddelfremstilling
MY123193A (en) Novel 2-(iminomethyl)amino-phenyl derivatives,preparation,application as medicines and compositions containing same
PT1155692E (pt) Utilizacao de paclitaxel estabilizado com albumina para a preparacao de um farmaco para o tratamento de tumores solidos e o farmaco assim obtido
NO20035496D0 (no) Substituerte sulfonamidforbindelser, fremgangsmåte for deres anvendelse sommedikament til behandling av CNS-forstyrrelser, overvekt og typeII-diabetes
ZA992951B (en) N-substituted aminotetralins as ligands for the neuropeptide Y Y5 receptor useful in the treatment of obesity and other disorders.
DE60034240D1 (de) Drogen zur behandlung maligner tumoren
DK1144386T3 (da) Polymorf form af telmisartan, fremgangsmåde til fremstilling deraf og anvendelse deraf til fremstilling af et lægemiddel
MY124146A (en) Novel 2-(iminomethyl) amino-phenyl derivatives, preparation, application as medicines and pharmaceutical compositions containing same
NO20054739L (no) Metode for okning av oral biotilgjengelighet av S-2'-("1-(2-etylbutyl)cyklo-heksyl!carbonyl!amino)fenyl!-2-metylpropanetioat
AU2003293593A1 (en) Pharmaceutical preparations, use of said preparations and method for increasing the bioavailability of medicaments for peroral administration
ITTO990784A0 (it) Procedimento di rafforzamento di attivita' antitumorale di farmacigrezzi, composizione contenente un farmaco grezzo rafforzante l'atti-
WO2000059489A8 (en) Methods and compositions for the treatment of psychotic and related disorders using ziprasidone metabolites
ES2138950T1 (es) Nuevo procedimiento.
PT1194415E (pt) Novos derivados da piperazinil-alquil-tiopirimidina composicoes farmaceuticas que os contem e um processo de preparacao da substancia activa
DK0966285T3 (da) Anvendelse af (+)mefloquin til behandling af malaria
IT1308678B1 (it) Siringa per infusione di farmaci.
BR0114395A (pt) Composição farmacêutica para administração por suprimento via oral
EE200100596A (et) Ülipuhas (1R,2S,4R)-(-)-2-[(2'-{N,N-dimetüülamino}etoksü)]-2-[fenüül]-1,7,7-tri[metüül]bitsüklo[2.2.1 ]heptaan ja selle farmatseutiliselt vastuvõetavad happeliitsoolad ning nimetatud ühendite, samutiravimite, mis sisaldavad üks või enam nimetatud üh
MY130814A (en) Oral pharmaceutical compositions containing non-steroidal anti-inflammatory drugs and method for preparing the same
DK1151746T3 (da) Mikro-kapsler til vedvarende frigivelse af lægemidler
DK1071397T3 (da) Levosimendan-holdige lægemidler til oral indgivelse med kontrolleret frisætning af det aktive middel
AU3749195A (en) Bis-2-aminopyridines, preparation method therefor and use tereof for controlling parasitic infections
NO20022896L (no) Substituerte 1- og 2-naftol mannich baser

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties