ES2138950T1 - Nuevo procedimiento. - Google Patents
Nuevo procedimiento.Info
- Publication number
- ES2138950T1 ES2138950T1 ES98953132T ES98953132T ES2138950T1 ES 2138950 T1 ES2138950 T1 ES 2138950T1 ES 98953132 T ES98953132 T ES 98953132T ES 98953132 T ES98953132 T ES 98953132T ES 2138950 T1 ES2138950 T1 ES 2138950T1
- Authority
- ES
- Spain
- Prior art keywords
- metoxi
- new procedure
- piridinil
- dimetil
- benzimidazole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
LA PRESENTE INVENCION SE REFIERE A UN NUEVO PROCEDIMIENTO PARA LA SINTESIS DE 5 - METOXI - 2 - [[(4 - METOXI - 3,5 - DIMETIL 2 - PIRIDINIL)METIL]SULFINIL] - 1 - H - BENZIMIDAZOL, CONOCIDO POR EL NOMBRE GENERICO DE OMEPRAZOL. ADEMAS, LA INVENCION SE REFIERE A LA FABRICACION DE UNA PREPARACION FARMACEUTICA DEL MISMO Y A SU UTILIZACION EN MEDICINA. EL NUEVO PROCEDIMIENTO PARA LA PREPARACION DE OMEPRAZOL COMPRENDE LA FASE DE OXIDAR 5 METOXI - 2 - [[(4 - METOXI - 3,5 - DIMETIL - 2 PIRIDINIL)METIL]TIO] - 1H - BENZIMIDAZOL EN UN DISOLVENTE ORGANICO CON UN AGENTE OXIDANTE, EN PRESENCIA DE UN COMPLEJO DE TITANIO Y, OPCIONALMENTE, EN PRESENCIA DE UNA BASE.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9704183A SE9704183D0 (sv) | 1997-11-14 | 1997-11-14 | New process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2138950T1 true ES2138950T1 (es) | 2000-02-01 |
Family
ID=20408989
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES98953132T Pending ES2138950T1 (es) | 1997-11-14 | 1998-11-03 | Nuevo procedimiento. |
Country Status (35)
| Country | Link |
|---|---|
| US (1) | US6303788B1 (es) |
| EP (1) | EP0964859A1 (es) |
| JP (1) | JP2001508466A (es) |
| KR (1) | KR20000070069A (es) |
| CN (1) | CN1145624C (es) |
| AR (1) | AR013740A1 (es) |
| AU (1) | AU750743B2 (es) |
| BR (1) | BR9806871A (es) |
| CA (1) | CA2276753A1 (es) |
| DE (1) | DE964859T1 (es) |
| DZ (1) | DZ2641A1 (es) |
| EE (1) | EE04154B1 (es) |
| ES (1) | ES2138950T1 (es) |
| GR (1) | GR990300046T1 (es) |
| HR (1) | HRP990218A2 (es) |
| HU (1) | HUP0003737A3 (es) |
| ID (1) | ID21999A (es) |
| IL (1) | IL130647A0 (es) |
| IN (1) | IN190801B (es) |
| IS (1) | IS5106A (es) |
| MA (1) | MA26564A1 (es) |
| MY (1) | MY118199A (es) |
| NO (1) | NO318197B1 (es) |
| NZ (1) | NZ336447A (es) |
| PL (1) | PL334701A1 (es) |
| RU (1) | RU2211218C2 (es) |
| SE (1) | SE9704183D0 (es) |
| SK (1) | SK87299A3 (es) |
| TN (1) | TNSN98202A1 (es) |
| TR (1) | TR199901643T1 (es) |
| TW (1) | TW588046B (es) |
| UA (1) | UA68342C2 (es) |
| WO (1) | WO1999025711A1 (es) |
| YU (1) | YU31199A (es) |
| ZA (1) | ZA989999B (es) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9301830D0 (sv) * | 1993-05-28 | 1993-05-28 | Ab Astra | New compounds |
| US5840737A (en) | 1996-01-04 | 1998-11-24 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
| US6489346B1 (en) | 1996-01-04 | 2002-12-03 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
| IL142703A (en) | 1998-11-10 | 2006-04-10 | Astrazeneca Ab | Crystalline form of omeprazole |
| UA72748C2 (en) | 1998-11-10 | 2005-04-15 | Astrazeneca Ab | A novel crystalline form of omeprazole |
| WO2002062786A1 (en) | 2001-02-02 | 2002-08-15 | Teva Pharmaceutical Industries Ltd. | Processes for the production of substituted 2-(2-pyridylmethyl) sulfinyl-1h-benzimidazoles |
| SE0203092D0 (en) | 2002-10-18 | 2002-10-18 | Astrazeneca Ab | Method for the synthesis of a benzimidazole compound |
| US8993599B2 (en) | 2003-07-18 | 2015-03-31 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
| US8906940B2 (en) | 2004-05-25 | 2014-12-09 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
| US7915422B2 (en) | 2004-10-11 | 2011-03-29 | Ranbaxy Laboratories Limited | Processes for the preparation of substituted sulfoxides |
| EP1801110A1 (en) | 2005-12-22 | 2007-06-27 | KRKA, tovarna zdravil, d.d., Novo mesto | Esomeprazole arginine salt |
| CN1810803B (zh) * | 2006-02-17 | 2010-11-17 | 中国科学院上海有机化学研究所 | 高对映体选择性制备(s)-奥美拉唑的方法 |
| CN101538264A (zh) * | 2008-03-19 | 2009-09-23 | 中国科学院成都有机化学有限公司 | 手性亚砜类化合物的制备新方法 |
| CN102603621B (zh) * | 2012-02-07 | 2013-09-04 | 成都苑东药业有限公司 | 一种新型手性亚砜化合物和以该化合物制备埃索美拉唑钠的方法 |
| CN106083819A (zh) * | 2016-06-08 | 2016-11-09 | 扬子江药业集团有限公司 | 一种奥美拉唑的制备方法 |
| ES2948511A1 (es) * | 2021-09-08 | 2023-09-13 | Fundacion Para La Investigacion Biomedica Del Hospital Univ De La Princesa | Derivados de n-sulfonilureas y su uso terapeutico |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE7804231L (sv) | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
| SE9002043D0 (sv) | 1990-06-07 | 1990-06-07 | Astra Ab | Improved method for synthesis |
| WO1993006097A1 (en) | 1991-09-20 | 1993-04-01 | Merck & Co., Inc. | Novel process for the preparation of anti-ulcer agents |
| SE504459C2 (sv) * | 1994-07-15 | 1997-02-17 | Astra Ab | Förfarande för framställning av substituerade sulfoxider |
-
1997
- 1997-11-14 SE SE9704183A patent/SE9704183D0/xx unknown
-
1998
- 1998-03-11 UA UA99073870A patent/UA68342C2/uk unknown
- 1998-11-02 ZA ZA989999A patent/ZA989999B/xx unknown
- 1998-11-02 TW TW087118172A patent/TW588046B/zh not_active IP Right Cessation
- 1998-11-02 IN IN3213DE1998 patent/IN190801B/en unknown
- 1998-11-02 AR ARP980105504A patent/AR013740A1/es unknown
- 1998-11-02 MY MYPI98004977A patent/MY118199A/en unknown
- 1998-11-03 KR KR1019997006290A patent/KR20000070069A/ko active IP Right Grant
- 1998-11-03 EP EP98953132A patent/EP0964859A1/en not_active Ceased
- 1998-11-03 WO PCT/SE1998/001984 patent/WO1999025711A1/en not_active Application Discontinuation
- 1998-11-03 YU YU31199A patent/YU31199A/sh unknown
- 1998-11-03 EE EEP199900391A patent/EE04154B1/xx not_active IP Right Cessation
- 1998-11-03 JP JP52827799A patent/JP2001508466A/ja not_active Ceased
- 1998-11-03 ES ES98953132T patent/ES2138950T1/es active Pending
- 1998-11-03 TR TR1999/01643T patent/TR199901643T1/xx unknown
- 1998-11-03 HU HU0003737A patent/HUP0003737A3/hu unknown
- 1998-11-03 PL PL98334701A patent/PL334701A1/xx unknown
- 1998-11-03 NZ NZ336447A patent/NZ336447A/en unknown
- 1998-11-03 DE DE0964859T patent/DE964859T1/de active Pending
- 1998-11-03 DZ DZ980251A patent/DZ2641A1/xx active
- 1998-11-03 BR BR9806871-7A patent/BR9806871A/pt not_active Application Discontinuation
- 1998-11-03 AU AU10582/99A patent/AU750743B2/en not_active Ceased
- 1998-11-03 CA CA002276753A patent/CA2276753A1/en not_active Abandoned
- 1998-11-03 CN CNB988017970A patent/CN1145624C/zh not_active Expired - Fee Related
- 1998-11-03 RU RU99117541/04A patent/RU2211218C2/ru not_active IP Right Cessation
- 1998-11-03 SK SK872-99A patent/SK87299A3/sk unknown
- 1998-11-03 US US09/194,647 patent/US6303788B1/en not_active Expired - Fee Related
- 1998-11-03 IL IL13064798A patent/IL130647A0/xx not_active IP Right Cessation
- 1998-11-03 ID IDW990692A patent/ID21999A/id unknown
- 1998-11-05 MA MA25335A patent/MA26564A1/fr unknown
- 1998-11-09 TN TNTNSN98202A patent/TNSN98202A1/fr unknown
-
1999
- 1999-07-02 NO NO19993298A patent/NO318197B1/no unknown
- 1999-07-02 IS IS5106A patent/IS5106A/is unknown
- 1999-07-13 HR HR990218A patent/HRP990218A2/hr not_active Application Discontinuation
-
2000
- 2000-07-31 GR GR990300046T patent/GR990300046T1/el unknown
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