ATE274052T1 - Fester träger für die zellkultur insbesondere für leberzellenkultur, biologischer reaktor und diese träger enthaltendes biologischer reaktor und ihre verwendung in einem künstliche leber vorrichtung - Google Patents
Fester träger für die zellkultur insbesondere für leberzellenkultur, biologischer reaktor und diese träger enthaltendes biologischer reaktor und ihre verwendung in einem künstliche leber vorrichtungInfo
- Publication number
- ATE274052T1 ATE274052T1 AT96932875T AT96932875T ATE274052T1 AT E274052 T1 ATE274052 T1 AT E274052T1 AT 96932875 T AT96932875 T AT 96932875T AT 96932875 T AT96932875 T AT 96932875T AT E274052 T1 ATE274052 T1 AT E274052T1
- Authority
- AT
- Austria
- Prior art keywords
- cell culture
- biological reactor
- support
- matrix material
- liver
- Prior art date
Links
- 238000004113 cell culture Methods 0.000 title abstract 3
- 239000007787 solid Substances 0.000 title abstract 2
- 210000004185 liver Anatomy 0.000 title 1
- 210000005229 liver cell Anatomy 0.000 title 1
- 239000011159 matrix material Substances 0.000 abstract 4
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 abstract 2
- 239000000835 fiber Substances 0.000 abstract 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 229910002092 carbon dioxide Inorganic materials 0.000 abstract 1
- 239000001569 carbon dioxide Substances 0.000 abstract 1
- 239000006260 foam Substances 0.000 abstract 1
- 239000012510 hollow fiber Substances 0.000 abstract 1
- 230000002209 hydrophobic effect Effects 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 210000004789 organ system Anatomy 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 238000006213 oxygenation reaction Methods 0.000 abstract 1
- 239000011148 porous material Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
- A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
- A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
- A61M1/3486—Biological, chemical treatment, e.g. chemical precipitation; treatment by absorbents
- A61M1/3489—Biological, chemical treatment, e.g. chemical precipitation; treatment by absorbents by biological cells, e.g. bioreactor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M21/00—Bioreactors or fermenters specially adapted for specific uses
- C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/06—Tubular
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/24—Gas permeable parts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
- C12M25/02—Membranes; Filters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
- C12M25/10—Hollow fibers or tubes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
- C12M25/14—Scaffolds; Matrices
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0068—General culture methods using substrates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Sustainable Development (AREA)
- Heart & Thoracic Surgery (AREA)
- Cell Biology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Clinical Laboratory Science (AREA)
- Vascular Medicine (AREA)
- Biodiversity & Conservation Biology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54038995A | 1995-10-06 | 1995-10-06 | |
| PCT/NL1996/000389 WO1997012960A2 (en) | 1995-10-06 | 1996-10-04 | Solid support for use in cell cultivation, especially for the cultivation of liver cells, biological reactor containing said solid support and the use thereof in a bio-artificial liver system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE274052T1 true ATE274052T1 (de) | 2004-09-15 |
Family
ID=24155248
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96932875T ATE274052T1 (de) | 1995-10-06 | 1996-10-04 | Fester träger für die zellkultur insbesondere für leberzellenkultur, biologischer reaktor und diese träger enthaltendes biologischer reaktor und ihre verwendung in einem künstliche leber vorrichtung |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6372495B1 (de) |
| EP (1) | EP0866849B1 (de) |
| JP (1) | JP4112616B2 (de) |
| AT (1) | ATE274052T1 (de) |
| AU (1) | AU714517B2 (de) |
| CA (1) | CA2244659C (de) |
| DE (1) | DE69633189T2 (de) |
| ES (1) | ES2227607T3 (de) |
| WO (1) | WO1997012960A2 (de) |
Families Citing this family (62)
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|---|---|---|---|---|
| US6306491B1 (en) | 1996-12-20 | 2001-10-23 | Gore Enterprise Holdings, Inc. | Respiratory aids |
| JP4222658B2 (ja) | 1998-06-23 | 2009-02-12 | テルモ株式会社 | 細胞支持基材、培養装置および液体処理装置 |
| DE19919242A1 (de) * | 1999-04-28 | 2000-11-02 | Creavis Tech & Innovation Gmbh | Modulare Zellträgersysteme für dreidimensionales Zellwachstum |
| JP3553858B2 (ja) * | 1999-08-25 | 2004-08-11 | 東洋紡績株式会社 | 血管網類似構造体を有する細胞培養用モジュール |
| RU2163148C1 (ru) * | 2000-01-19 | 2001-02-20 | Соловьев Валерий Владимирович | Биологическая искусственная печень |
| JP2002112763A (ja) * | 2000-10-10 | 2002-04-16 | Nipro Corp | 細胞培養容器 |
| US20040084791A1 (en) * | 2001-01-18 | 2004-05-06 | Kyu-Tek Han | Biodegradale polyurethane capsules and manufacturing method thereof |
| CA2853267C (en) | 2002-04-08 | 2018-06-26 | Octane Biotech Inc. | Automated tissue engineering system comprising sensors linked to a microprocessor |
| AU2002354097A1 (en) * | 2002-12-05 | 2004-06-23 | Amcite Research, Ltd. | Tissue culture apparatus |
| DE10335130A1 (de) * | 2003-07-31 | 2005-02-24 | Blue Membranes Gmbh | Immobilisierung von Katalysatoren auf porösen Körpern auf Kohlenstoffbasis |
| ITMO20030081A1 (it) * | 2003-03-21 | 2004-09-22 | Rand Srl | Bioreattore, particolarmente per organi bioartificiali. |
| EP1479760A1 (de) * | 2003-05-19 | 2004-11-24 | ProBioGen AG | Künstliches Immunorgan |
| US20070048732A1 (en) * | 2005-08-30 | 2007-03-01 | Hepahope, Inc. | Chemosensitivity tester |
| US20050130254A1 (en) | 2003-12-16 | 2005-06-16 | Park Sung-Soo | Drug testing system with bio-artificial liver |
| WO2005039396A2 (en) * | 2003-10-22 | 2005-05-06 | Medtrain Technologies, Llc | Tissue engineered construct analytical imaging system and method of obtaining and analyzing images of tissue engineered constructs |
| US7393687B2 (en) * | 2004-07-16 | 2008-07-01 | William Marsh Rice University | Biomimetic 3-dimensional scaffold with metabolic stream separation for bioartificial liver device |
| JP2006211950A (ja) * | 2005-02-03 | 2006-08-17 | Kaneka Corp | 細胞の生存率を測定する方法 |
| WO2007021919A1 (en) | 2005-08-12 | 2007-02-22 | Clemson University | Co-culture bioreactor system |
| WO2007025154A1 (en) * | 2005-08-24 | 2007-03-01 | Hepahope, Inc. | Chemosensitivity tester |
| WO2008060788A2 (en) | 2006-10-11 | 2008-05-22 | The General Hospital Corporation | Compositions, methods, and devices for treating liver disease |
| JP2010519936A (ja) * | 2007-03-05 | 2010-06-10 | カリディアンビーシーティー、インコーポレーテッド | 中空繊維バイオリアクター内における細胞の動きを制御する方法 |
| EP2152851B1 (de) * | 2007-04-06 | 2018-04-25 | Terumo BCT, Inc. | Verbesserte bioreaktoroberflächen |
| WO2008128165A2 (en) * | 2007-04-13 | 2008-10-23 | Caridianbct, Inc. | Cell expansion system and methods of use |
| US20080294361A1 (en) * | 2007-05-24 | 2008-11-27 | Popp Shane M | Intelligent execution system for the monitoring and execution of vaccine manufacturing |
| TW200927273A (en) * | 2007-09-13 | 2009-07-01 | Applied Process Technology Inc | Water treatment bioreactor using polyester hollow filaments |
| WO2009108654A2 (en) * | 2008-02-25 | 2009-09-03 | Clemson University | Differential pressure pump system |
| JP5271781B2 (ja) * | 2008-11-25 | 2013-08-21 | 日機装株式会社 | 血球除去モジュール及び血球除去モジュールの製造方法 |
| JP5368948B2 (ja) * | 2008-11-21 | 2013-12-18 | 三菱レイヨン株式会社 | 細胞培養用モジュール |
| WO2012009606A1 (en) * | 2010-07-16 | 2012-01-19 | University Of Utah Research Foundation | Electrophysiological recording system and methods of using same |
| US9877822B2 (en) | 2012-04-24 | 2018-01-30 | Biostage, Inc. | Engineered tissue scaffolds and supports therefor |
| WO2014110300A1 (en) | 2013-01-09 | 2014-07-17 | Harvard Apparatus Regenerative Technology | Synthetic scaffolds |
| US9670447B2 (en) * | 2013-01-29 | 2017-06-06 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Microfabricated polymeric vessel mimetics |
| CN105793411B (zh) * | 2013-11-16 | 2018-04-17 | 泰尔茂比司特公司 | 生物反应器中的细胞扩增 |
| US10179896B2 (en) | 2015-05-12 | 2019-01-15 | Baker Group, LLP | Method and system for a bioartificial organ |
| WO2017088928A1 (de) | 2015-11-27 | 2017-06-01 | Technische Universität Ilmenau | Verfahren und anordnung zur fermentation |
| US11104874B2 (en) | 2016-06-07 | 2021-08-31 | Terumo Bct, Inc. | Coating a bioreactor |
| US11685883B2 (en) | 2016-06-07 | 2023-06-27 | Terumo Bct, Inc. | Methods and systems for coating a cell growth surface |
| BE1024733B1 (fr) | 2016-11-09 | 2018-06-14 | Univercells Sa | Matrice de croissance cellulaire |
| CA3248436A1 (en) | 2017-09-01 | 2025-02-21 | Lonza Walkersville, Inc. | END-TO-END AUTOMATION OF CELL THERAPY |
| KR20250167120A (ko) | 2017-12-20 | 2025-11-28 | 유니버셀스 테크놀로지스 에스.에이. | 생물반응기 및 관련 방법 |
| US20240034976A1 (en) * | 2018-01-25 | 2024-02-01 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Rolled scaffold for large scale cell culture in monolayer |
| US12227727B2 (en) * | 2018-02-28 | 2025-02-18 | Pop Test Oncology Llc | Medical devices and uses thereof |
| CN108485965A (zh) * | 2018-03-21 | 2018-09-04 | 重庆理工大学 | 一种膜式板状生物人工肝反应器 |
| JP7396777B2 (ja) | 2018-09-28 | 2023-12-12 | オクタン バイオテック インコーポレーテッド | 磁気分離 |
| IL281472B2 (en) * | 2018-10-03 | 2025-03-01 | Pluri Biotech Ltd | Modular bioreactor |
| ES2974790T3 (es) * | 2018-11-27 | 2024-07-01 | Gambro Lundia Ab | Preparación de un aparato de tratamiento sanguíneo extracorpóreo |
| JP7477091B2 (ja) | 2018-12-21 | 2024-05-01 | オクタン バイオテック インコーポレーテッド | モジュラー生物製剤生産ユニットのためのカルーセル |
| CA3123449A1 (en) | 2018-12-21 | 2020-06-25 | Lonza Walkersville, Inc. | Automated production of viral vectors |
| KR102810534B1 (ko) | 2018-12-28 | 2025-05-22 | 옥테인 바이오테크 인코포레이티드 | 제어된 환경 존을 포함하는 세포 배양 및 조직 공학 시스템 |
| KR20210124233A (ko) * | 2019-01-04 | 2021-10-14 | 프레마스 바이오테크 프라이빗 리미티드 | 다차원 세포 배양 장치 및 방법 |
| CN113498432A (zh) | 2019-02-08 | 2021-10-12 | 隆萨沃克斯维尔股份有限公司 | 用于自动化生物反应器的细胞浓缩方法和装置 |
| CN109967004B (zh) * | 2019-03-12 | 2024-08-13 | 叶涵辰 | 一种强化传热的流化床反应器 |
| CN114269406B (zh) * | 2019-04-05 | 2026-02-13 | 奇德尼实验室公司 | 用于肾脏治疗的吸着剂 |
| US12467025B2 (en) | 2019-09-06 | 2025-11-11 | Amolifescience Co., Ltd. | Cell culture sheet and large-capacity cell culture device including same |
| IL292409A (en) | 2019-10-24 | 2022-06-01 | Octane Biotech Inc | A cell culture chamber with enhanced cell contact surfaces |
| KR20220097457A (ko) | 2019-11-11 | 2022-07-07 | 론자 워커스빌 아이엔씨. | 자동화된 세포 처리를 위한 품질 관리 방법 |
| AT522766B1 (de) * | 2019-11-21 | 2021-01-15 | Spitzer Gesmbh | Filtervorrichtung |
| US20230052695A1 (en) * | 2020-02-05 | 2023-02-16 | Membio Inc. | Cell culture bioreactor with zone control |
| KR20210138976A (ko) * | 2020-05-13 | 2021-11-22 | 아주대학교산학협력단 | 중공섬유와 나노섬유로 만들어진 나노시트 복합체를 이용한 바이오리액터 |
| US20250034503A1 (en) * | 2021-12-22 | 2025-01-30 | Cellular Agriculture Ltd | Cell culture construct |
| GB202212079D0 (en) * | 2022-08-18 | 2022-10-05 | Cellular Agriculture Ltd | Perfusion bioreactor |
| CN120787146A (zh) * | 2023-02-06 | 2025-10-14 | 伊维瓦医疗有限公司 | 血管内人工胰腺 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US4537860A (en) * | 1982-12-08 | 1985-08-27 | Monsanto Company | Static cell culture maintenance system |
| IL75554A (en) * | 1985-06-18 | 1993-01-14 | Yeda Res & Dev | Matrix for cell cultivation in vitro |
| US4721096A (en) * | 1986-04-18 | 1988-01-26 | Marrow-Tech Incorporated | Process for replicating bone marrow in vitro and using the same |
| US5605835A (en) * | 1988-05-23 | 1997-02-25 | Regents Of The University Of Minnesota | Bioreactor device with application as a bioartificial liver |
| US5079168A (en) | 1988-08-10 | 1992-01-07 | Endotronics, Inc. | Cell culture apparatus |
| JPH02109966A (ja) | 1988-10-20 | 1990-04-23 | Kirin Brewery Co Ltd | ラジアルフロー式充填層型バイオリアクタ |
| US5262320A (en) | 1990-06-18 | 1993-11-16 | Massachusetts Institute Of Technology | Cell-culturing apparatus and method employing a macroporous support |
| US5549674A (en) * | 1992-03-02 | 1996-08-27 | The Regents Of The University Of Michigan | Methods and compositions of a bioartificial kidney suitable for use in vivo or ex vivo |
| DE4218917C2 (de) | 1992-06-10 | 1996-07-11 | Schmitz Klaus Peter Dr Ing Hab | Zellkulturmatrix |
| GB9227134D0 (en) | 1992-12-31 | 1993-02-24 | Fuller Jess P | Cell support structure |
| DE4322746A1 (de) | 1993-07-08 | 1995-01-12 | Augustinus Dr Med Bader | Verfahren und Vorrichtung zur Behandlung von Zellkulturen |
| WO1995021911A1 (en) * | 1994-02-09 | 1995-08-17 | Unisyn Technologies, Inc. | High performance cell culture bioreactor and method |
| US5622857A (en) * | 1995-08-08 | 1997-04-22 | Genespan Corporation | High performance cell culture bioreactor and method |
| JPH07298876A (ja) * | 1994-03-09 | 1995-11-14 | Res Dev Corp Of Japan | 通液性細胞培養担体と、この担体を用いる培養方法お よび培養装置 |
-
1996
- 1996-10-04 CA CA002244659A patent/CA2244659C/en not_active Expired - Fee Related
- 1996-10-04 AU AU71482/96A patent/AU714517B2/en not_active Ceased
- 1996-10-04 ES ES96932875T patent/ES2227607T3/es not_active Expired - Lifetime
- 1996-10-04 EP EP96932875A patent/EP0866849B1/de not_active Expired - Lifetime
- 1996-10-04 JP JP51417397A patent/JP4112616B2/ja not_active Expired - Fee Related
- 1996-10-04 US US09/051,273 patent/US6372495B1/en not_active Expired - Lifetime
- 1996-10-04 WO PCT/NL1996/000389 patent/WO1997012960A2/en not_active Ceased
- 1996-10-04 AT AT96932875T patent/ATE274052T1/de not_active IP Right Cessation
- 1996-10-04 DE DE69633189T patent/DE69633189T2/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US6372495B1 (en) | 2002-04-16 |
| DE69633189D1 (de) | 2004-09-23 |
| CA2244659A1 (en) | 1997-04-10 |
| JPH11514229A (ja) | 1999-12-07 |
| EP0866849A1 (de) | 1998-09-30 |
| WO1997012960A2 (en) | 1997-04-10 |
| CA2244659C (en) | 2007-05-01 |
| WO1997012960A3 (en) | 2001-12-20 |
| AU714517B2 (en) | 2000-01-06 |
| AU7148296A (en) | 1997-04-28 |
| JP4112616B2 (ja) | 2008-07-02 |
| ES2227607T3 (es) | 2005-04-01 |
| EP0866849B1 (de) | 2004-08-18 |
| DE69633189T2 (de) | 2005-08-11 |
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