ATE273293T1 - Aminoalkenylbenzoyl-benzofurane oder benzothiophene, verfahren zur ihrer herstellung und sie enthaltende zubereitungen - Google Patents

Aminoalkenylbenzoyl-benzofurane oder benzothiophene, verfahren zur ihrer herstellung und sie enthaltende zubereitungen

Info

Publication number
ATE273293T1
ATE273293T1 AT01963120T AT01963120T ATE273293T1 AT E273293 T1 ATE273293 T1 AT E273293T1 AT 01963120 T AT01963120 T AT 01963120T AT 01963120 T AT01963120 T AT 01963120T AT E273293 T1 ATE273293 T1 AT E273293T1
Authority
AT
Austria
Prior art keywords
aminoalkenylbenzoyl
benzofuranes
benzothiophenes
production
preparations containing
Prior art date
Application number
AT01963120T
Other languages
German (de)
English (en)
Inventor
Jean-Louis Assens
Claude Bernhart
Frederique Cabanel-Haudricourt
Santos Victor Dos
Patrick Gautier
Dino Nisato
Original Assignee
Sanofi Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo filed Critical Sanofi Synthelabo
Application granted granted Critical
Publication of ATE273293T1 publication Critical patent/ATE273293T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/84Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80Radicals substituted by oxygen atoms
AT01963120T 2000-08-23 2001-08-23 Aminoalkenylbenzoyl-benzofurane oder benzothiophene, verfahren zur ihrer herstellung und sie enthaltende zubereitungen ATE273293T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0010835A FR2813307B1 (fr) 2000-08-23 2000-08-23 Aminoalkenylbenzoyl-benzofurannes ou benzothiophenes, leur procede de preparation et les compositions les contenant
PCT/FR2001/002656 WO2002016338A1 (fr) 2000-08-23 2001-08-23 Aminoalkenylbenzoyl-benzofuranes ou benzothiophenes, leur procede de preparation et les compositions les contenant

Publications (1)

Publication Number Publication Date
ATE273293T1 true ATE273293T1 (de) 2004-08-15

Family

ID=8853675

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01963120T ATE273293T1 (de) 2000-08-23 2001-08-23 Aminoalkenylbenzoyl-benzofurane oder benzothiophene, verfahren zur ihrer herstellung und sie enthaltende zubereitungen

Country Status (25)

Country Link
US (1) US6946483B2 (US06946483-20050920-C00040.png)
EP (1) EP1315708B1 (US06946483-20050920-C00040.png)
JP (1) JP4918209B2 (US06946483-20050920-C00040.png)
KR (1) KR20030023768A (US06946483-20050920-C00040.png)
CN (1) CN1471519A (US06946483-20050920-C00040.png)
AT (1) ATE273293T1 (US06946483-20050920-C00040.png)
AU (1) AU2001284154A1 (US06946483-20050920-C00040.png)
BG (1) BG107553A (US06946483-20050920-C00040.png)
BR (1) BR0113350A (US06946483-20050920-C00040.png)
CA (1) CA2415846A1 (US06946483-20050920-C00040.png)
CZ (1) CZ2003520A3 (US06946483-20050920-C00040.png)
DE (1) DE60104866T2 (US06946483-20050920-C00040.png)
EA (1) EA200300063A1 (US06946483-20050920-C00040.png)
FR (1) FR2813307B1 (US06946483-20050920-C00040.png)
HU (1) HUP0302892A3 (US06946483-20050920-C00040.png)
IL (1) IL153637A0 (US06946483-20050920-C00040.png)
IS (1) IS6676A (US06946483-20050920-C00040.png)
MA (1) MA26944A1 (US06946483-20050920-C00040.png)
MX (1) MXPA03001592A (US06946483-20050920-C00040.png)
NO (1) NO20030801L (US06946483-20050920-C00040.png)
OA (1) OA12358A (US06946483-20050920-C00040.png)
PL (1) PL362123A1 (US06946483-20050920-C00040.png)
SK (1) SK2112003A3 (US06946483-20050920-C00040.png)
WO (1) WO2002016338A1 (US06946483-20050920-C00040.png)
ZA (1) ZA200300746B (US06946483-20050920-C00040.png)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI641593B (zh) 2009-01-16 2018-11-21 美商艾克塞里克斯公司 包含n-(4-{〔6,7-雙(甲氧基)喹啉-4-基〕氧基}苯基)-n’-(4-氟苯基)環丙烷-1,1-二甲醯胺之蘋果酸鹽之醫藥組合物及其用途
AU2011202542A1 (en) 2010-07-14 2012-02-02 Indian Institute Of Science Benzothiophene carboxamide compounds, composition and applications thereof
CN107935972B (zh) * 2017-11-14 2020-06-02 沈阳药科大学 5-[2-羟基-3-(异丙胺基)丙氧基]苯并呋喃类衍生物及其应用
CN107857748B (zh) * 2017-11-14 2020-06-02 沈阳药科大学 5-[2-羟基-3-(烷胺基)丙氧基]苯并呋喃类化合物及其应用
CN107827849B (zh) * 2017-11-14 2020-06-02 沈阳药科大学 6-[2-羟基-3-(烷胺基)丙氧基]苯并呋喃类化合物及其应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3248401A (en) * 1966-04-26 Diethylaminoe hoxybenzoyl benzofurans
US4831054A (en) * 1988-04-18 1989-05-16 Taro Pharmaceuticals, Ltd. 2-Alkyl-3-benzoylbenzofurans useful for treating cardiac arrhythmia
AT391316B (de) * 1988-09-15 1990-09-25 Ebewe Arzneimittel Neue thienyloxy-alkylamin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
FR2665444B1 (fr) * 1990-08-06 1992-11-27 Sanofi Sa Derives d'amino-benzofuranne, benzothiophene ou indole, leur procede de preparation ainsi que les compositions les contenant.
US5364880A (en) * 1993-06-16 1994-11-15 Advanced Therapies, Inc. Compound for treatment of cardiac arrhythmia, synthesis, and methods of use
US6756388B1 (en) * 1993-10-12 2004-06-29 Pfizer Inc. Benzothiophenes and related compounds as estrogen agonists
US5523309A (en) * 1995-03-10 1996-06-04 Eli Lilly And Company Benzofuran pharmaceutical compounds
US5622974A (en) * 1995-03-10 1997-04-22 Eli Lilly And Company α-substituted-3-benzyl-benzofurans
CA2220991A1 (en) * 1995-06-26 1997-01-16 Eli Lilly And Company Benzothiophene compounds
US5827876A (en) * 1996-04-09 1998-10-27 American Home Products Corporation Inhibition of bone loss by 3-(4-acrylamidobenzoyl) benzo b!-thiophenes
WO1999054325A1 (fr) * 1998-04-17 1999-10-28 Senga Pharmaceutical Laboratory Inc. Derives 1-heteroindene et compositions medicinales a base de tels derives

Also Published As

Publication number Publication date
KR20030023768A (ko) 2003-03-19
WO2002016338A1 (fr) 2002-02-28
EP1315708A1 (fr) 2003-06-04
DE60104866T2 (de) 2005-10-20
MXPA03001592A (es) 2003-09-10
NO20030801L (no) 2003-04-23
WO2002016338A8 (fr) 2002-05-10
BR0113350A (pt) 2003-07-08
OA12358A (fr) 2006-05-16
PL362123A1 (en) 2004-10-18
US6946483B2 (en) 2005-09-20
EA200300063A1 (ru) 2003-08-28
IL153637A0 (en) 2003-07-06
DE60104866D1 (de) 2004-09-16
HUP0302892A3 (en) 2005-02-28
NO20030801D0 (no) 2003-02-20
EP1315708B1 (fr) 2004-08-11
IS6676A (is) 2003-01-13
JP2004506726A (ja) 2004-03-04
JP4918209B2 (ja) 2012-04-18
MA26944A1 (fr) 2004-12-20
FR2813307A1 (fr) 2002-03-01
CZ2003520A3 (cs) 2003-05-14
HUP0302892A2 (hu) 2003-12-29
AU2001284154A1 (en) 2002-03-04
CN1471519A (zh) 2004-01-28
SK2112003A3 (en) 2003-08-05
CA2415846A1 (fr) 2002-02-28
FR2813307B1 (fr) 2002-11-08
BG107553A (en) 2004-01-30
ZA200300746B (en) 2004-02-10
US20030187060A1 (en) 2003-10-02

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