ATE271050T1 - Herstellungsverfahren für derivate der naphthyridin-3-carbonsäure - Google Patents

Herstellungsverfahren für derivate der naphthyridin-3-carbonsäure

Info

Publication number
ATE271050T1
ATE271050T1 AT00958776T AT00958776T ATE271050T1 AT E271050 T1 ATE271050 T1 AT E271050T1 AT 00958776 T AT00958776 T AT 00958776T AT 00958776 T AT00958776 T AT 00958776T AT E271050 T1 ATE271050 T1 AT E271050T1
Authority
AT
Austria
Prior art keywords
naphthyridine
derivatives
production process
carbonic acid
carbonic
Prior art date
Application number
AT00958776T
Other languages
German (de)
English (en)
Inventor
Sungwook Cho
Moonji-Dong
Hoon Choi
John David Hayler
Original Assignee
Lg Life Sciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lg Life Sciences Ltd filed Critical Lg Life Sciences Ltd
Application granted granted Critical
Publication of ATE271050T1 publication Critical patent/ATE271050T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT00958776T 1999-09-03 2000-09-01 Herstellungsverfahren für derivate der naphthyridin-3-carbonsäure ATE271050T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9920917.3A GB9920917D0 (en) 1999-09-03 1999-09-03 Novel process
PCT/GB2000/003366 WO2001018002A1 (en) 1999-09-03 2000-09-01 Process for production of naphthyridine-3-carboxylic acid derivatives

Publications (1)

Publication Number Publication Date
ATE271050T1 true ATE271050T1 (de) 2004-07-15

Family

ID=10860353

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00958776T ATE271050T1 (de) 1999-09-03 2000-09-01 Herstellungsverfahren für derivate der naphthyridin-3-carbonsäure

Country Status (23)

Country Link
US (1) US7232907B2 (enExample)
EP (1) EP1214321B1 (enExample)
JP (1) JP4208464B2 (enExample)
KR (1) KR100724311B1 (enExample)
CN (1) CN1275963C (enExample)
AR (1) AR029002A1 (enExample)
AT (1) ATE271050T1 (enExample)
AU (1) AU773722B2 (enExample)
BR (1) BRPI0013751B8 (enExample)
CA (1) CA2383753C (enExample)
CO (1) CO5470281A1 (enExample)
DE (1) DE60012196T2 (enExample)
DK (1) DK1214321T3 (enExample)
ES (1) ES2223574T3 (enExample)
GB (1) GB9920917D0 (enExample)
HK (1) HK1047093B (enExample)
MX (1) MXPA02002355A (enExample)
MY (1) MY125309A (enExample)
PT (1) PT1214321E (enExample)
SI (1) SI1214321T1 (enExample)
TW (1) TWI274753B (enExample)
WO (1) WO2001018002A1 (enExample)
ZA (1) ZA200201781B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2281817C (en) * 1999-06-29 2008-07-29 Smithkline Beecham Corporation Methods of use of fluoroquinolone compounds against maxillary sinus pathogenic bacteria
GB9920919D0 (en) * 1999-09-03 1999-11-10 Sb Pharmco Inc Novel compound
GB9920917D0 (en) 1999-09-03 1999-11-10 Sb Pharmco Inc Novel process
PT1412078E (pt) 2001-08-02 2009-01-08 Lg Life Sciences Ltd Processos para a produção de derivados amino-protegidos da 4- aminometileno-pirrolidin-3-ona, gemifloxacina ou um seu sal
KR100517638B1 (ko) * 2002-04-08 2005-09-28 주식회사 엘지생명과학 게미플록사신 산염의 새로운 제조방법
KR100653334B1 (ko) * 2003-03-07 2006-12-04 주식회사 엘지생명과학 4-아미노메틸-3-알콕시이미노피롤리딘 메탄설폰산염의 신규한 제조 방법
WO2006134431A1 (en) * 2005-05-03 2006-12-21 Ranbaxy Laboratories Limited Formate salt of gemifloxacin
WO2006134608A1 (en) * 2005-06-15 2006-12-21 Hetero Drugs Limited Gemifloxacin process and polymorphs
WO2008053324A1 (en) * 2006-10-31 2008-05-08 Orchid Chemicals & Pharmaceuticals Limited An improved process for the preparation of gemifloxacin mesylate

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57134482A (en) 1981-02-13 1982-08-19 Dainippon Pharmaceut Co Ltd 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8- naphthyridine-3-carboxylic acid-3/2 hydrate and its preparation
IN162769B (enExample) 1984-11-13 1988-07-09 Kyorin Seiyaku Kk
NZ222047A (en) 1986-10-08 1991-01-29 Bristol Myers Co Quinoline - or naphthyridine - carboxylic acid anti-bacterial agents
JPH01100165A (ja) 1987-10-13 1989-04-18 Shionogi & Co Ltd オキシムまたはヒドロキシアミン誘導体系抗菌剤
US4920120A (en) 1988-01-25 1990-04-24 Warner-Lambert Company Antibacterial agents
JPH0356479A (ja) 1989-07-24 1991-03-12 Takeshi Yokota 水溶性キノロン誘導体のｐ‐トルエンスルホン酸塩
RU2049777C1 (ru) 1989-08-16 1995-12-10 Пфайзер Инк. Азабицикло-хинолон-карбоновые кислоты или их фармацевтически приемлемые кислотно-аддитивные соли и промежуточные продукты для их получения
US5137892A (en) 1990-12-12 1992-08-11 Abbott Laboratories Quinoline, naphthyridine and pyridobenzoxazine derivatives
EP0541086A1 (en) 1991-11-08 1993-05-12 Kaken Pharmaceutical Co., Ltd. Antibacterial 6-fluoro-quinolones having an oxime group on the substituent in position 7
JPH0673056A (ja) 1992-08-26 1994-03-15 Kaken Pharmaceut Co Ltd キノリンカルボン酸誘導体およびその塩
US5776944A (en) 1994-06-16 1998-07-07 Lg Chemical Ltd. 7-(4-aminomethyl-3-methyloxyiminopyrroplidin-1-yl)-1-cyclopropyl-6-flu oro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid and the process for the preparation thereof
DK0688772T3 (da) 1994-06-16 1999-11-01 Lg Chemical Ltd Quinolincarboxylsyrederivater med 7-(4-aminomethyl-3-oxim)-pyrrolidinsubstituenter og fremgangsmåde til deres fremstilling
JP3449658B2 (ja) 1994-12-21 2003-09-22 杏林製薬株式会社 安定性に優れた８−アルコキシキノロンカルボン酸水和物並びにその製造方法
FI974441A7 (fi) 1995-06-06 1997-12-05 Pfizer Vedettömän 7-(/1alfa,5alfa,6alfa/-6-amino-3-atsabisyklo(3.1.0)heks-3-y yli)-6-fluori-1-(2,4-difluorifenyyli)-1,4-dihydro-4-okso,1,8-naftyridi ini-3-karboksyylihapon metaanisulfonihapposuolan uusi kidemuoto
CA2228752C (en) 1995-08-11 2002-12-10 Pfizer Inc. (1s,2s)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidin-1-yl)-1-propanol methanesulfonate trihydrate
ES2198564T3 (es) 1996-03-29 2004-02-01 Smithkline Beecham Corporation Dihidrato de eprosartan y un procedimiento para su produccion y formulacion.
MA24500A1 (fr) * 1997-03-21 1998-10-01 Lg Life Sciences Ltd Derive du sel d'acide carboxylique de naphthyridine .
KR100286874B1 (ko) 1998-03-04 2001-04-16 성재갑 보호된 4-아미노메틸-피롤리딘-3-온의 제조방법
US6127400A (en) 1998-05-29 2000-10-03 Pharmacia & Upjohn Company Salts of diamine pyrrolidine
GB9820405D0 (en) 1998-09-18 1998-11-11 Smithkline Beecham Plc Process
EP1223935B1 (en) 1999-06-29 2008-01-09 LG Life Sciences, Ltd. Use of gemifloxacin compounds against bacteria
AU6947900A (en) 1999-09-01 2001-03-26 Smithkline Beecham Corporation Methods of use of fluoroquinolone compounds against bacteria
GB9920919D0 (en) 1999-09-03 1999-11-10 Sb Pharmco Inc Novel compound
GB9920917D0 (en) 1999-09-03 1999-11-10 Sb Pharmco Inc Novel process
EP1242079A4 (en) 1999-09-22 2003-01-22 Smithkline Beecham Methods of anti-bacterial use of fluoroquinolonic compounds
KR20010091379A (ko) 2000-03-15 2001-10-23 성재갑 7-(4-아미노메틸-3-옥심)피롤리딘 치환체를 갖는 퀴놀린카르복실산 유도체의 신규 제조방법
KR20020018560A (ko) 2000-09-01 2002-03-08 성재갑 3-아미노메틸-4-ｚ-메톡시이미노피롤리딘의 신규 제조방법

Also Published As

Publication number Publication date
CN1275963C (zh) 2006-09-20
DK1214321T3 (da) 2004-10-25
BR0013751A (pt) 2002-05-07
AU773722B2 (en) 2004-06-03
ES2223574T3 (es) 2005-03-01
KR100724311B1 (ko) 2007-06-04
DE60012196T2 (de) 2005-08-18
TWI274753B (en) 2007-03-01
AU7019700A (en) 2001-04-10
US7232907B2 (en) 2007-06-19
MY125309A (en) 2006-07-31
HK1047093B (en) 2005-05-27
JP2003508532A (ja) 2003-03-04
KR20020041421A (ko) 2002-06-01
EP1214321A1 (en) 2002-06-19
CA2383753A1 (en) 2001-03-15
PT1214321E (pt) 2004-10-29
CO5470281A1 (es) 2004-12-30
BRPI0013751B8 (pt) 2021-05-25
AR029002A1 (es) 2003-06-04
JP4208464B2 (ja) 2009-01-14
SI1214321T1 (en) 2004-12-31
CA2383753C (en) 2011-06-28
HK1047093A1 (en) 2003-02-07
DE60012196D1 (de) 2004-08-19
US20050176961A1 (en) 2005-08-11
BR0013751B1 (pt) 2013-02-05
CN1377350A (zh) 2002-10-30
WO2001018002A1 (en) 2001-03-15
MXPA02002355A (es) 2004-07-16
EP1214321B1 (en) 2004-07-14
GB9920917D0 (en) 1999-11-10
ZA200201781B (en) 2003-06-25

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