ATE268754T1 - N-substituierte indoline als östrogene mittel - Google Patents
N-substituierte indoline als östrogene mittelInfo
- Publication number
- ATE268754T1 ATE268754T1 AT00913549T AT00913549T ATE268754T1 AT E268754 T1 ATE268754 T1 AT E268754T1 AT 00913549 T AT00913549 T AT 00913549T AT 00913549 T AT00913549 T AT 00913549T AT E268754 T1 ATE268754 T1 AT E268754T1
- Authority
- AT
- Austria
- Prior art keywords
- estrogenic agents
- substituted indolines
- indolines
- substituted
- estrogenic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Obesity (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Reproductive Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US26256999A | 1999-03-04 | 1999-03-04 | |
PCT/US2000/004343 WO2000051982A1 (en) | 1999-03-04 | 2000-02-22 | N-substituted indolines as estrogenic agents |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE268754T1 true ATE268754T1 (de) | 2004-06-15 |
Family
ID=22998068
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00913549T ATE268754T1 (de) | 1999-03-04 | 2000-02-22 | N-substituierte indoline als östrogene mittel |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP1159267B1 (de) |
JP (1) | JP2002538140A (de) |
CN (1) | CN1152861C (de) |
AR (1) | AR022798A1 (de) |
AT (1) | ATE268754T1 (de) |
AU (1) | AU3497700A (de) |
CA (1) | CA2364911A1 (de) |
DE (1) | DE60011401T2 (de) |
DK (1) | DK1159267T3 (de) |
ES (1) | ES2220434T3 (de) |
HK (1) | HK1038922B (de) |
PT (1) | PT1159267E (de) |
TW (1) | TWI220898B (de) |
WO (1) | WO2000051982A1 (de) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2016518449A (ja) * | 2013-05-15 | 2016-06-23 | インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation | インドール製剤を調製するためのプロセスおよび中間体 |
CN103664733B (zh) * | 2013-12-10 | 2016-04-20 | 邯郸惠达化工有限公司 | 一种吲哚啉的制备方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0802183B1 (de) * | 1996-04-19 | 2001-10-10 | American Home Products Corporation | Östrogene Verbindungen |
-
2000
- 2000-02-18 TW TW089102843A patent/TWI220898B/zh not_active IP Right Cessation
- 2000-02-22 EP EP00913549A patent/EP1159267B1/de not_active Expired - Lifetime
- 2000-02-22 DE DE60011401T patent/DE60011401T2/de not_active Expired - Fee Related
- 2000-02-22 WO PCT/US2000/004343 patent/WO2000051982A1/en active IP Right Grant
- 2000-02-22 CN CNB008044619A patent/CN1152861C/zh not_active Expired - Fee Related
- 2000-02-22 AT AT00913549T patent/ATE268754T1/de not_active IP Right Cessation
- 2000-02-22 PT PT00913549T patent/PT1159267E/pt unknown
- 2000-02-22 AU AU34977/00A patent/AU3497700A/en not_active Abandoned
- 2000-02-22 ES ES00913549T patent/ES2220434T3/es not_active Expired - Lifetime
- 2000-02-22 DK DK00913549T patent/DK1159267T3/da active
- 2000-02-22 CA CA002364911A patent/CA2364911A1/en not_active Abandoned
- 2000-02-22 JP JP2000602210A patent/JP2002538140A/ja active Pending
- 2000-03-01 AR ARP000100899A patent/AR022798A1/es not_active Application Discontinuation
-
2002
- 2002-01-22 HK HK02100496.7A patent/HK1038922B/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DK1159267T3 (da) | 2004-08-09 |
DE60011401D1 (de) | 2004-07-15 |
AR022798A1 (es) | 2002-09-04 |
CA2364911A1 (en) | 2000-09-08 |
DE60011401T2 (de) | 2005-07-14 |
ES2220434T3 (es) | 2004-12-16 |
TWI220898B (en) | 2004-09-11 |
PT1159267E (pt) | 2004-09-30 |
HK1038922B (zh) | 2004-12-03 |
EP1159267A1 (de) | 2001-12-05 |
JP2002538140A (ja) | 2002-11-12 |
AU3497700A (en) | 2000-09-21 |
HK1038922A1 (en) | 2002-04-04 |
EP1159267B1 (de) | 2004-06-09 |
CN1152861C (zh) | 2004-06-09 |
WO2000051982A1 (en) | 2000-09-08 |
CN1342143A (zh) | 2002-03-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CY2016002I1 (el) | Ν-υποκατεστημενο καρβαμουλοξυαλκυλιο - παραγωγα αζολιου | |
ATE359275T1 (de) | Substituierte bizyclische derivate verwendbar als antitumor mittel | |
DE60032601D1 (de) | Als antikrebsmittel verwendbare heterocyklische derivate | |
ATE253067T1 (de) | Diazabicyloderivate als nikotin-acetylcholin- rezeptorliganden | |
ATE275553T1 (de) | Isothiazole derivate verwendbar als antikrebsmittel | |
DE60020812D1 (de) | Heteroaryl-substituierte chinolin-2-on derivate verwendbar als antikrebsmittel | |
NO20014286L (no) | Trefaseseparator | |
DE50001729D1 (de) | N-(indolcarbonyl-)piperazinderivate als 5-ht2a-rezeptor liganden | |
NO20022803L (no) | Substituerte indol-mannichbaser | |
ATE299142T1 (de) | Phenylpiperazin-derivate als inhibitoren der serotonin-wiederaufnahme | |
DE60008239D1 (de) | Indolylpiperidinderivate als antihistaminische und antiallergische mittel | |
DE60028085D1 (de) | Piperidinyloxy- und pyrrolidinyloxyphenyloxazolidinone als antibakterielle mittel | |
NO20020565L (no) | Interleukin-5-hemmende 6-azauracilderivater | |
ATE254621T1 (de) | Thienoisoxazolyl- und thienylpyrazolyl-phenoxy substituierte propyl derivate als d4 antagonisten | |
ATE240317T1 (de) | Indolderivate als pkc-inhibitoren | |
DE60021384D1 (de) | Indolderivate | |
ATE282606T1 (de) | Indolderivate als serotonergische mittel | |
IS6434A (is) | Nýjar indól afleiður | |
NO20020306D0 (no) | Indolderivater | |
AU3859400A (en) | N-substituted benzoyl indoles as estrogenic agents | |
ATE236150T1 (de) | (4-piperidinyl)-1h-2-benzopyran derivate verwendbar als antipsychotische mittel | |
ATE268754T1 (de) | N-substituierte indoline als östrogene mittel | |
NO20015920D0 (no) | Etansulfonyl-piperidin-derivater | |
ATE241615T1 (de) | 5-heteroaryl-substituierte indole | |
DK1073651T3 (da) | Indolylderivater som serotonerge midler |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 1159267 Country of ref document: EP |
|
REN | Ceased due to non-payment of the annual fee |