ATE267012T1 - Tetrahydro-beta carbolinverbindungen - Google Patents

Tetrahydro-beta carbolinverbindungen

Info

Publication number
ATE267012T1
ATE267012T1 AT97916854T AT97916854T ATE267012T1 AT E267012 T1 ATE267012 T1 AT E267012T1 AT 97916854 T AT97916854 T AT 97916854T AT 97916854 T AT97916854 T AT 97916854T AT E267012 T1 ATE267012 T1 AT E267012T1
Authority
AT
Austria
Prior art keywords
tetrahydro
compounds
beta
carboline compounds
beta carboline
Prior art date
Application number
AT97916854T
Other languages
English (en)
Inventor
James E Audia
David L G Nelson
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE267012T1 publication Critical patent/ATE267012T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT97916854T 1996-03-25 1997-03-24 Tetrahydro-beta carbolinverbindungen ATE267012T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1411996P 1996-03-25 1996-03-25
PCT/US1997/004473 WO1997035578A1 (en) 1996-03-25 1997-03-24 Tetrahydro-beta-carboline compounds

Publications (1)

Publication Number Publication Date
ATE267012T1 true ATE267012T1 (de) 2004-06-15

Family

ID=21763645

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97916854T ATE267012T1 (de) 1996-03-25 1997-03-24 Tetrahydro-beta carbolinverbindungen

Country Status (20)

Country Link
US (1) US5886004A (de)
EP (1) EP0942722B1 (de)
JP (1) JP2001509130A (de)
KR (1) KR20000004963A (de)
CN (1) CN1225584A (de)
AT (1) ATE267012T1 (de)
AU (1) AU714024B2 (de)
BR (1) BR9708347A (de)
CA (1) CA2248874A1 (de)
CZ (1) CZ298098A3 (de)
DE (1) DE69729211T2 (de)
EA (1) EA199800867A1 (de)
ES (1) ES2221049T3 (de)
IL (1) IL126062A0 (de)
NO (1) NO984445L (de)
NZ (1) NZ331827A (de)
PL (1) PL329212A1 (de)
TR (1) TR199801910T2 (de)
WO (1) WO1997035578A1 (de)
YU (1) YU41998A (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5886003A (en) * 1996-03-25 1999-03-23 Eli Lilly And Company Methods of treating or ameliorating the symptoms of venomous bites and stings
ES2152860B1 (es) * 1998-10-23 2001-08-16 Finaf 92 Sa Forma cristalina de la nefazodona y procedimiento para su preparacion.
AU4856600A (en) 1999-05-18 2000-12-05 Synaptic Pharmaceutical Corporation Use of agonists or antagonists of the 5-ht7 receptor to treat disorders of the bladder
US6444477B1 (en) * 2000-11-28 2002-09-03 Pharmagene Laboratories Limited Assay method for detecting 5-HT2B antagonists
DE10252667A1 (de) * 2002-11-11 2004-05-27 Grünenthal GmbH Spirocyclische Cyclohexan-Derivate
US20080161419A1 (en) * 2004-02-20 2008-07-03 Shinobu Akuzawa Prophylactic Antimigraine Agents
US7550499B2 (en) * 2004-05-12 2009-06-23 Bristol-Myers Squibb Company Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
MX2007008434A (es) * 2005-01-19 2007-07-25 Squibb Bristol Myers Co Derivados de 2-fenoxi-n-(1,3,4-tiadizol-2il)piridin-3-amina y compuestos relacionados como inhibidores del receptor p2y1 para el tratamiento de trastornos tromboembolicos.
WO2006085510A1 (ja) * 2005-02-08 2006-08-17 Astellas Pharma Inc. 過敏性腸症候群の治療薬
WO2007002634A1 (en) * 2005-06-27 2007-01-04 Bristol-Myers Squibb Company Carbocycle and heterocycle antagonists of p2y1 receptor useful in the treatment of thrombotic conditions
WO2007002635A2 (en) * 2005-06-27 2007-01-04 Bristol-Myers Squibb Company C-linked cyclic antagonists of p2y1 receptor useful in the treatment of thrombotic conditions
ES2360818T3 (es) 2005-06-27 2011-06-09 Bristol-Myers Squibb Company Miméticos de urea lineal antagonistas del receptor p2y, útiles en el tratamiento de afecciones trombóticas.
US7728008B2 (en) * 2005-06-27 2010-06-01 Bristol-Myers Squibb Company N-linked heterocyclic antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
CA2617473A1 (en) * 2005-08-08 2007-02-15 Astellas Pharma Inc. Acylguanidine derivative or salt thereof
US7960569B2 (en) * 2006-10-17 2011-06-14 Bristol-Myers Squibb Company Indole antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
US9751847B2 (en) 2010-10-14 2017-09-05 University Of Utah Research Foundation Methods and compositions related to neuroactive thiazoline compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5500431A (en) * 1993-04-14 1996-03-19 Eli Lilly And Company Tetrahydro-β-carbolines
EP0749313A4 (de) * 1994-03-11 2001-10-24 Lilly Co Eli Verfahren zur behandlung von mit dem 5-ht2b-rezeptor verbundenen zuständen
US5663178A (en) * 1995-02-06 1997-09-02 Eli Lilly And Company Tetrahydro-beta carbolines
AU724646B2 (en) * 1996-03-15 2000-09-28 Eli Lilly And Company Method of treating common cold or allergic rhinitis
US5886003A (en) * 1996-03-25 1999-03-23 Eli Lilly And Company Methods of treating or ameliorating the symptoms of venomous bites and stings

Also Published As

Publication number Publication date
US5886004A (en) 1999-03-23
IL126062A0 (en) 1999-05-09
NZ331827A (en) 2000-02-28
WO1997035578A1 (en) 1997-10-02
BR9708347A (pt) 1999-08-03
DE69729211T2 (de) 2005-05-04
TR199801910T2 (xx) 1998-12-21
DE69729211D1 (en) 2004-06-24
CN1225584A (zh) 1999-08-11
NO984445L (no) 1998-11-20
NO984445D0 (no) 1998-09-24
AU2536197A (en) 1997-10-17
CA2248874A1 (en) 1997-10-02
EP0942722A1 (de) 1999-09-22
KR20000004963A (ko) 2000-01-25
CZ298098A3 (cs) 1999-02-17
EP0942722B1 (de) 2004-05-19
EA199800867A1 (ru) 1999-02-25
JP2001509130A (ja) 2001-07-10
PL329212A1 (en) 1999-03-15
EP0942722A4 (de) 2002-06-05
YU41998A (sh) 1999-07-28
ES2221049T3 (es) 2004-12-16
AU714024B2 (en) 1999-12-16

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties