ATE266667T1 - Neue verbindungen zur erzeugung von chemilumineszenz mit hilfe einer peroxidase - Google Patents
Neue verbindungen zur erzeugung von chemilumineszenz mit hilfe einer peroxidaseInfo
- Publication number
- ATE266667T1 ATE266667T1 AT98943173T AT98943173T ATE266667T1 AT E266667 T1 ATE266667 T1 AT E266667T1 AT 98943173 T AT98943173 T AT 98943173T AT 98943173 T AT98943173 T AT 98943173T AT E266667 T1 ATE266667 T1 AT E266667T1
- Authority
- AT
- Austria
- Prior art keywords
- peroxidase
- chemiluminescence
- new compounds
- generating chemiluminescence
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/113—Esters of phosphoric acids with unsaturated acyclic alcohols
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/02—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with only hydrogen, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/08—Aza-anthracenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/64—Acridine or hydrogenated acridine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms
- C07F9/655363—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a six-membered ring
- C07F9/655372—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K11/00—Luminescent materials, e.g. electroluminescent or chemiluminescent
- C09K11/06—Luminescent materials, e.g. electroluminescent or chemiluminescent containing organic luminescent materials
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Materials Engineering (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92738197A | 1997-09-12 | 1997-09-12 | |
| PCT/US1998/015734 WO1999014220A1 (en) | 1997-09-12 | 1998-08-12 | Novel compounds for generating chemiluminescence with a peroxidase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE266667T1 true ATE266667T1 (de) | 2004-05-15 |
Family
ID=25454661
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98943173T ATE266667T1 (de) | 1997-09-12 | 1998-08-12 | Neue verbindungen zur erzeugung von chemilumineszenz mit hilfe einer peroxidase |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US6696569B2 (https=) |
| EP (1) | EP1015461B1 (https=) |
| JP (1) | JP4431272B2 (https=) |
| AT (1) | ATE266667T1 (https=) |
| AU (1) | AU9102398A (https=) |
| CA (1) | CA2300071C (https=) |
| DE (1) | DE69823845T2 (https=) |
| WO (1) | WO1999014220A1 (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6017769A (en) * | 1998-06-17 | 2000-01-25 | Lumigen, Inc. | Non-enzymatic methods of generating chemiluminescence from acridan alkenes |
| WO2001017435A1 (en) | 1999-09-07 | 2001-03-15 | Microvena Corporation | Retrievable septal defect closure device |
| EP1322670B1 (en) * | 2000-06-26 | 2005-12-21 | Lumigen, Inc. | Electrochemiluminescence from acridan compounds |
| US6872828B2 (en) | 2001-12-20 | 2005-03-29 | Lumigen, Inc. | Compounds for generating chemiluminescence with a peroxidase |
| WO2003053934A1 (en) | 2001-12-20 | 2003-07-03 | Lumigen, Inc. | Improved compounds for generating chemiluminescence with a peroxidase |
| US20100056762A1 (en) | 2001-05-11 | 2010-03-04 | Old Lloyd J | Specific binding proteins and uses thereof |
| EP1392359B2 (en) | 2001-05-11 | 2013-03-13 | Ludwig Institute for Cancer Research Ltd. | Specific binding proteins and uses thereof |
| US7560556B2 (en) * | 2001-12-20 | 2009-07-14 | Lumigen, Inc. | Assay methods using chemiluminescent detection of peroxidase |
| US6897036B2 (en) | 2002-06-06 | 2005-05-24 | Lumigen, Inc. | Fluorescent detection of peroxidase enzymes |
| EP1763584B1 (en) * | 2004-07-02 | 2009-04-22 | Promega Corporation | Compositions and processes for the extraction and detection of microbial atp |
| WO2006116683A1 (en) * | 2005-04-27 | 2006-11-02 | The Trustees Of The University Of Pennsylvania | Nanostructure enhanced luminescence |
| WO2006116687A2 (en) * | 2005-04-27 | 2006-11-02 | The Trustees Of The University Of Pennsylvania | Nanoassays |
| US7919019B2 (en) * | 2005-04-27 | 2011-04-05 | The Trustees Of The University Of Pennsylvania | Nanostructure enhanced luminescent devices |
| WO2007082899A1 (en) | 2006-01-17 | 2007-07-26 | Vib Vzw | Inhibitors of prolyl-hydroxylase 1 for the treatment of skeletal muscle degeneration |
| US7732153B2 (en) | 2006-05-09 | 2010-06-08 | Beckman Coulter, Inc. | Nonseparation assay methods |
| US7799534B2 (en) * | 2006-05-09 | 2010-09-21 | Beckman Coulter, Inc. | Nonseparation assay methods |
| EP2068929A4 (en) * | 2006-09-15 | 2010-04-28 | Life Science Pharmaceuticals | METHOD OF DETECTING AND TREATING SKIN DISORDERS |
| US8173423B2 (en) | 2006-11-07 | 2012-05-08 | Vib Vzw | Diagnosis and treatment of T-cell acute lymphoblastic leukemia |
| WO2009062027A1 (en) * | 2007-11-07 | 2009-05-14 | Beckman Coulter, Inc. | Nonseparation assay methods using peroxide generating enzymes |
| US20100273189A1 (en) * | 2009-02-27 | 2010-10-28 | Beckman Coulter, Inc. | Non separation assays with selective signal inhibitors |
| CA2753598C (en) * | 2009-02-27 | 2018-07-10 | Beckman Coulter, Inc. | Solution phase homogeneous assays |
| US20110097723A1 (en) * | 2009-09-19 | 2011-04-28 | Qun Liu | Methods and reagents for analyte detection |
| EP2535027B1 (en) | 2011-06-17 | 2022-08-17 | The Procter & Gamble Company | Absorbent article having improved absorption properties |
| GB2510285B (en) | 2011-11-21 | 2018-12-12 | Procter & Gamble | Absorbent articles with improved absorption properties |
| CN104761584A (zh) * | 2015-02-27 | 2015-07-08 | 北京利德曼生化股份有限公司 | 吖啶酯衍生物及其合成方法和应用 |
| EP3821249B1 (en) | 2018-07-13 | 2022-06-29 | 3M Innovative Properties Company | Specific binding chemiluminescent assay |
| US12379379B2 (en) | 2018-07-13 | 2025-08-05 | Neogen Food Safety Us Holdco Corporation | Assay |
| CN115433229B (zh) * | 2022-08-29 | 2025-07-25 | 长沙创新药物工业技术研究院有限公司 | 一种化学发光底物的制备方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1327361C (en) * | 1988-01-14 | 1994-03-01 | Nihon Nohyaku Co., Ltd. | Ketenedithioacetal derivative and processes for producing the same as well as a composition containing the same |
| EP0361470B1 (en) * | 1988-09-30 | 1993-12-22 | Fujirebio Inc. | Method for the chemiluminescence assay of the activity of peroxidase |
| EP0422252B1 (en) * | 1989-04-28 | 1995-07-26 | Toray Industries, Inc. | Method for detecting a substance using chemiluminescence |
| US5324835A (en) * | 1990-03-30 | 1994-06-28 | Biosensor Laboratories Co., Ltd. | Pyridazinoquinoxalinones for use as chemiluminescent agents |
| US5491072A (en) * | 1993-05-17 | 1996-02-13 | Lumigen, Inc. | N-alkylacridan carboxyl derivatives useful for chemiluminescent detection |
| US5648484A (en) * | 1995-03-07 | 1997-07-15 | Schering Corporation | Catalytic enantioselective synthesis of a spriofused azetidinone |
| JP3169383B2 (ja) * | 1996-01-16 | 2001-05-21 | ルミゲン インク | ホスファターゼ酵素で化学発光を生成させるための化合物、組成物および方法 |
| US6126870A (en) * | 1997-09-12 | 2000-10-03 | Lumigen, Inc. | Chemiluminescent labeling compounds |
-
1998
- 1998-08-12 EP EP98943173A patent/EP1015461B1/en not_active Expired - Lifetime
- 1998-08-12 AT AT98943173T patent/ATE266667T1/de not_active IP Right Cessation
- 1998-08-12 DE DE69823845T patent/DE69823845T2/de not_active Expired - Lifetime
- 1998-08-12 WO PCT/US1998/015734 patent/WO1999014220A1/en not_active Ceased
- 1998-08-12 JP JP2000511769A patent/JP4431272B2/ja not_active Expired - Lifetime
- 1998-08-12 CA CA002300071A patent/CA2300071C/en not_active Expired - Lifetime
- 1998-08-12 AU AU91023/98A patent/AU9102398A/en not_active Abandoned
-
2001
- 2001-04-11 US US09/833,050 patent/US6696569B2/en not_active Expired - Lifetime
-
2004
- 2004-01-09 US US10/754,750 patent/US6891057B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US20040144948A1 (en) | 2004-07-29 |
| US20010039345A1 (en) | 2001-11-08 |
| US6891057B2 (en) | 2005-05-10 |
| WO1999014220A1 (en) | 1999-03-25 |
| JP2001516760A (ja) | 2001-10-02 |
| CA2300071C (en) | 2009-04-07 |
| EP1015461A1 (en) | 2000-07-05 |
| EP1015461A4 (en) | 2001-07-11 |
| AU9102398A (en) | 1999-04-05 |
| JP4431272B2 (ja) | 2010-03-10 |
| US6696569B2 (en) | 2004-02-24 |
| DE69823845T2 (de) | 2005-04-28 |
| DE69823845D1 (de) | 2004-06-17 |
| CA2300071A1 (en) | 1999-03-25 |
| EP1015461B1 (en) | 2004-05-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |