ATE280241T1 - Chemilumineszierende zusammensetzungen und entsprechende verfahren - Google Patents

Chemilumineszierende zusammensetzungen und entsprechende verfahren

Info

Publication number
ATE280241T1
ATE280241T1 AT98940778T AT98940778T ATE280241T1 AT E280241 T1 ATE280241 T1 AT E280241T1 AT 98940778 T AT98940778 T AT 98940778T AT 98940778 T AT98940778 T AT 98940778T AT E280241 T1 ATE280241 T1 AT E280241T1
Authority
AT
Austria
Prior art keywords
compositions
methods
peroxidase
compounds
double bond
Prior art date
Application number
AT98940778T
Other languages
English (en)
Inventor
Hashem Akhavan-Tafti
Original Assignee
Lumigen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lumigen Inc filed Critical Lumigen Inc
Application granted granted Critical
Publication of ATE280241T1 publication Critical patent/ATE280241T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00—Luminescent materials, e.g. electroluminescent or chemiluminescent
    • C09K11/06—Luminescent materials, e.g. electroluminescent or chemiluminescent containing organic luminescent materials
    • C09K11/07—Luminescent materials, e.g. electroluminescent or chemiluminescent containing organic luminescent materials having chemically-interreactive components, e.g. reactive chemiluminescent compositions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Materials Engineering (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Luminescent Compositions (AREA)
AT98940778T 1997-09-12 1998-08-12 Chemilumineszierende zusammensetzungen und entsprechende verfahren ATE280241T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/928,793 US5922558A (en) 1997-09-12 1997-09-12 Methods and compositions for generating chemiluminescence with a peroxidase
PCT/US1998/015813 WO1999014358A1 (en) 1997-09-12 1998-08-12 Chemiluminescence compositions and methods

Publications (1)

Publication Number Publication Date
ATE280241T1 true ATE280241T1 (de) 2004-11-15

Family

ID=25456769

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98940778T ATE280241T1 (de) 1997-09-12 1998-08-12 Chemilumineszierende zusammensetzungen und entsprechende verfahren

Country Status (9)

Country Link
US (1) US5922558A (de)
EP (1) EP1019525B1 (de)
JP (1) JP4790905B2 (de)
AT (1) ATE280241T1 (de)
AU (1) AU733086C (de)
CA (1) CA2300096C (de)
DE (1) DE69827152T2 (de)
ES (1) ES2230710T3 (de)
WO (1) WO1999014358A1 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU716233B2 (en) * 1996-01-16 2000-02-24 Lumigen, Inc. Compounds, compositions and methods for generating chemiluminescence with phosphatase enzymes
US6126870A (en) * 1997-09-12 2000-10-03 Lumigen, Inc. Chemiluminescent labeling compounds
US6017769A (en) * 1998-06-17 2000-01-25 Lumigen, Inc. Non-enzymatic methods of generating chemiluminescence from acridan alkenes
US7186568B1 (en) * 2000-06-26 2007-03-06 Lumigen Inc. Electrochemiluminescence from acridan compounds
AU2002215610B2 (en) * 2000-06-26 2004-05-06 Lumigen, Inc. Electrochemiluminescence from acridan compounds
US6872828B2 (en) 2001-12-20 2005-03-29 Lumigen, Inc. Compounds for generating chemiluminescence with a peroxidase
US7560556B2 (en) * 2001-12-20 2009-07-14 Lumigen, Inc. Assay methods using chemiluminescent detection of peroxidase
AU2002352881B2 (en) * 2001-12-20 2008-11-06 Lumigen, Inc. Improved compounds for generating chemiluminescence with a peroxidase
US6897036B2 (en) * 2002-06-06 2005-05-24 Lumigen, Inc. Fluorescent detection of peroxidase enzymes
US7390670B2 (en) 2003-02-20 2008-06-24 Lumigen, Inc. Signalling compounds and methods for detecting hydrogen peroxide
US20060205094A1 (en) * 2005-03-14 2006-09-14 Lumigen, Inc. Methods using novel chemiluminescent labels
US7682839B2 (en) * 2005-03-14 2010-03-23 Lumigen, Inc. Methods using novel chemiluminescent labels
WO2006116686A2 (en) * 2005-04-27 2006-11-02 The Trustees Of The University Of Pennsylvania Nanostructure enhanced luminescent devices
US20090246888A1 (en) * 2005-04-27 2009-10-01 The Trustees Of The University Of Pennsylvania Nanoassays
WO2006116683A1 (en) * 2005-04-27 2006-11-02 The Trustees Of The University Of Pennsylvania Nanostructure enhanced luminescence
US7566573B2 (en) * 2005-12-19 2009-07-28 Idexx Laboratories, Inc. Dual standard curve immunoassay
US7732153B2 (en) 2006-05-09 2010-06-08 Beckman Coulter, Inc. Nonseparation assay methods
US7799534B2 (en) * 2006-05-09 2010-09-21 Beckman Coulter, Inc. Nonseparation assay methods
US7674629B2 (en) * 2007-03-15 2010-03-09 Saint Louis University Method for improving chemiluminescent signal
US20100240070A1 (en) * 2007-11-07 2010-09-23 Beckman Coulter, Inc. Nonseparation Assay Methods Using Peroxide Generating Enzymes
CN101178402B (zh) * 2007-12-06 2011-08-24 武汉赛欣生物技术有限公司 聚合酶标记抗体的制备方法
US20090162876A1 (en) * 2007-12-20 2009-06-25 Abbott Laboratories Myeloperoxidase assays
US8652442B2 (en) 2008-11-03 2014-02-18 Washington University Bioluminescence imaging of myeloperoxidase activity in vivo, methods, compositions and apparatuses therefor
US9029092B2 (en) 2009-02-27 2015-05-12 Beckman Coulter, Inc. Solution phase homogeneous assays
CN102333885A (zh) * 2009-02-27 2012-01-25 贝克曼考尔特公司 使用选择性信号抑制剂的非分离式测定
US20110097723A1 (en) * 2009-09-19 2011-04-28 Qun Liu Methods and reagents for analyte detection
US9075055B2 (en) 2013-03-15 2015-07-07 Hycor Biomedical, Inc. Device and associated methods for performing luminescence and fluorescence measurements of a sample
US9383336B2 (en) 2014-04-04 2016-07-05 General Electric Company System and method for flat panel detector gel and blot imaging
CN104761584A (zh) * 2015-02-27 2015-07-08 北京利德曼生化股份有限公司 吖啶酯衍生物及其合成方法和应用
WO2017045709A1 (en) * 2015-09-16 2017-03-23 General Electric Company System and method for flat panel detector gel and blot imaging
CN112400113B (zh) 2018-07-13 2022-04-15 3M创新有限公司 特异性结合化学发光测定法
CN112400025A (zh) 2018-07-13 2021-02-23 3M创新有限公司 测定
CN113295678B (zh) * 2021-05-14 2022-11-08 济南迪曼生物科技有限公司 一种电化学发光清洗液

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0361470B1 (de) * 1988-09-30 1993-12-22 Fujirebio Inc. Verfahren zur Bestimmung von Peroxidase-Aktivität unter Verwendung von Chemilumineszenz
DE69021161T2 (de) * 1989-04-28 1995-11-30 Toray Industries Verfahren zur Bestimmung einer Substanz durch Verwendung von chemilumineszenz.
WO1991001002A1 (en) * 1989-07-13 1991-01-24 N.V. Innogenetics S.A. Chemiluminescent compositions, chemiluminescent processes and their uses in analytical assays
US5324835A (en) * 1990-03-30 1994-06-28 Biosensor Laboratories Co., Ltd. Pyridazinoquinoxalinones for use as chemiluminescent agents
US5629168A (en) * 1992-02-10 1997-05-13 British Technology Group Limited Chemiluminescent enhancers
US5552298A (en) * 1992-10-23 1996-09-03 Lumigen, Inc. Enzyme-catalyzed chemiluminescence from hydroxyaryl cyclic diacylhydrazide compounds
US5512451A (en) * 1993-04-01 1996-04-30 British Technology Group Limited Enhancement of chemiluminescent reactions
US5670644A (en) * 1993-05-17 1997-09-23 Lumigen, Inc. Acridan compounds
US5491072A (en) * 1993-05-17 1996-02-13 Lumigen, Inc. N-alkylacridan carboxyl derivatives useful for chemiluminescent detection
US5723295A (en) * 1993-05-17 1998-03-03 Lumigen, Inc. Methods, acridan compounds and kits for producing light
US5523212A (en) * 1993-05-17 1996-06-04 Lumigen, Inc. Aryl N-alkylacridanthiocarboxylate derivatives useful for chemiluminescent detection
US5593845A (en) * 1993-05-17 1997-01-14 Lumigen, Inc. Aryl N-alkylacridancarboxylate derivatives useful for chemiluminescent detection
DE19548375A1 (de) * 1995-12-27 1997-07-03 Behringwerke Ag Immunologische Bestimmungsmethode
AU716233B2 (en) * 1996-01-16 2000-02-24 Lumigen, Inc. Compounds, compositions and methods for generating chemiluminescence with phosphatase enzymes
ATE364629T1 (de) * 1996-01-22 2007-07-15 Curis Inc Methoden zur herstellung von op-1 morphogen analoge

Also Published As

Publication number Publication date
JP4790905B2 (ja) 2011-10-12
ES2230710T3 (es) 2005-05-01
EP1019525A4 (de) 2003-01-02
EP1019525B1 (de) 2004-10-20
DE69827152T2 (de) 2006-03-09
JP2001516589A (ja) 2001-10-02
US5922558A (en) 1999-07-13
WO1999014358A1 (en) 1999-03-25
AU8897598A (en) 1999-04-05
AU733086C (en) 2002-01-03
CA2300096A1 (en) 1999-03-25
DE69827152D1 (de) 2004-11-25
EP1019525A1 (de) 2000-07-19
CA2300096C (en) 2010-02-09
AU733086B2 (en) 2001-05-03

Similar Documents

Publication Publication Date Title
ATE280241T1 (de) Chemilumineszierende zusammensetzungen und entsprechende verfahren
CA2300071A1 (en) Novel compounds for generating chemiluminescence with a peroxidase
DE69935408D1 (de) Chemilumineszente markierungsverbindungen
WO2001000865A3 (en) Amperometric sensor
DE69432382D1 (de) N-Alkylacridancarboxylderivate, geeignet für die Detektion von Chemilumineszenz
DE60321333D1 (de) Tetrahydropyranyl-cyclopentyl-tetrahydropyridopyridin-modulatoren der chemokin-rezeptor-aktivität
NO20074925L (no) Stabiliserende enzymaktivitet i elektrokjemiske biosensorer
ATE31734T1 (de) Katalysierte kolorimetrische und fluorimetrische substrate fuer peroxidaseenzym-bestimmungen.
ATE210178T1 (de) Bleichsystem
ES2122145T3 (es) Fosfiniloximetil-cetonas peptidicas como inhibidores de la enzima convertida de la interleuquina-1 beta.
TR200101497T2 (tr) Lipolitik enzim varyantları
AU7532501A (en) Method for increasing luminescence assay sensitivity
DK0915851T3 (da) Dibenzodihydropyridincarboxyl-estre og deres anvendelse i kemiluminiscens-analyse-fremgangsmåder
ATE266867T1 (de) Chemiluminiszenz-nachweis von hydrolytischen enzymen mittels eines acridans
PT2096110E (pt) Derivados de acridano-9-ditiocarboxilato para gerar quimiluminescência com uma peroxidase.
ATE323285T1 (de) Nicht-enzymatische methoden zur erzeugung von chemilumineszenz bei acridan-alkenen
ATE540966T1 (de) Von phenoxazinon abgeleitete neue enzymsubstrate und deren verwendung als entwickler bei der detektion von mikroorganismen mit peptidaseaktivität
DE69128181D1 (de) Enzymtests
NO980812L (no) Anvendelse av vanadiumbromperoksydase som et signalgenererende enzym for kjemilumineserende systemer, testkits og analytiske metoder
CA2251803A1 (en) Assay of peroxidase activity
DE59808166D1 (de) Verwendung von 2-methyl-thiazolidin-2,4-dicarbonsäure als mukolytikum
AU656572B2 (en) Chemiluminescent method and compositions
ATE261124T1 (de) Biotin-peg-substrat für einen lipase-assay
FR2779430B1 (fr) Dithio-bis-nitrobenzenes substitues et leurs applications
WO2003044223A3 (en) Phosphine-containing formulations for chemiluminescent luciferase assays

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1019525

Country of ref document: EP

REN Ceased due to non-payment of the annual fee