AU9102398A - Novel compounds for generating chemiluminescence with a peroxidase - Google Patents

Novel compounds for generating chemiluminescence with a peroxidase Download PDF

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Publication number
AU9102398A
AU9102398A AU91023/98A AU9102398A AU9102398A AU 9102398 A AU9102398 A AU 9102398A AU 91023/98 A AU91023/98 A AU 91023/98A AU 9102398 A AU9102398 A AU 9102398A AU 9102398 A AU9102398 A AU 9102398A
Authority
AU
Australia
Prior art keywords
substituted
compound
groups
atoms
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU91023/98A
Other languages
English (en)
Inventor
Hashem Akhavan-Tafti
Zahra Arghavani
Renuka De Silva
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lumigen Inc
Original Assignee
Lumigen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lumigen Inc filed Critical Lumigen Inc
Publication of AU9102398A publication Critical patent/AU9102398A/en
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/113—Esters of phosphoric acids with unsaturated acyclic alcohols
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/02—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with only hydrogen, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/08—Aza-anthracenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/64—Acridine or hydrogenated acridine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms
    • C07F9/655363—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a six-membered ring
    • C07F9/655372—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00—Luminescent materials, e.g. electroluminescent or chemiluminescent
    • C09K11/06—Luminescent materials, e.g. electroluminescent or chemiluminescent containing organic luminescent materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Materials Engineering (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Enzymes And Modification Thereof (AREA)
AU91023/98A 1997-09-12 1998-08-12 Novel compounds for generating chemiluminescence with a peroxidase Abandoned AU9102398A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US92738197A 1997-09-12 1997-09-12
US08927381 1997-09-12
PCT/US1998/015734 WO1999014220A1 (en) 1997-09-12 1998-08-12 Novel compounds for generating chemiluminescence with a peroxidase

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2004200649A Division AU2004200649B2 (en) 1997-09-12 2004-02-18 Novel compounds for generating chemiluminescence with a peroxidase

Publications (1)

Publication Number Publication Date
AU9102398A true AU9102398A (en) 1999-04-05

Family

ID=25454661

Family Applications (1)

Application Number Title Priority Date Filing Date
AU91023/98A Abandoned AU9102398A (en) 1997-09-12 1998-08-12 Novel compounds for generating chemiluminescence with a peroxidase

Country Status (8)

Country Link
US (2) US6696569B2 (https=)
EP (1) EP1015461B1 (https=)
JP (1) JP4431272B2 (https=)
AT (1) ATE266667T1 (https=)
AU (1) AU9102398A (https=)
CA (1) CA2300071C (https=)
DE (1) DE69823845T2 (https=)
WO (1) WO1999014220A1 (https=)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6017769A (en) * 1998-06-17 2000-01-25 Lumigen, Inc. Non-enzymatic methods of generating chemiluminescence from acridan alkenes
WO2001017435A1 (en) 1999-09-07 2001-03-15 Microvena Corporation Retrievable septal defect closure device
EP1322670B1 (en) * 2000-06-26 2005-12-21 Lumigen, Inc. Electrochemiluminescence from acridan compounds
US6872828B2 (en) 2001-12-20 2005-03-29 Lumigen, Inc. Compounds for generating chemiluminescence with a peroxidase
WO2003053934A1 (en) 2001-12-20 2003-07-03 Lumigen, Inc. Improved compounds for generating chemiluminescence with a peroxidase
US20100056762A1 (en) 2001-05-11 2010-03-04 Old Lloyd J Specific binding proteins and uses thereof
EP1392359B2 (en) 2001-05-11 2013-03-13 Ludwig Institute for Cancer Research Ltd. Specific binding proteins and uses thereof
US7560556B2 (en) * 2001-12-20 2009-07-14 Lumigen, Inc. Assay methods using chemiluminescent detection of peroxidase
US6897036B2 (en) 2002-06-06 2005-05-24 Lumigen, Inc. Fluorescent detection of peroxidase enzymes
EP1763584B1 (en) * 2004-07-02 2009-04-22 Promega Corporation Compositions and processes for the extraction and detection of microbial atp
WO2006116683A1 (en) * 2005-04-27 2006-11-02 The Trustees Of The University Of Pennsylvania Nanostructure enhanced luminescence
WO2006116687A2 (en) * 2005-04-27 2006-11-02 The Trustees Of The University Of Pennsylvania Nanoassays
US7919019B2 (en) * 2005-04-27 2011-04-05 The Trustees Of The University Of Pennsylvania Nanostructure enhanced luminescent devices
WO2007082899A1 (en) 2006-01-17 2007-07-26 Vib Vzw Inhibitors of prolyl-hydroxylase 1 for the treatment of skeletal muscle degeneration
US7732153B2 (en) 2006-05-09 2010-06-08 Beckman Coulter, Inc. Nonseparation assay methods
US7799534B2 (en) * 2006-05-09 2010-09-21 Beckman Coulter, Inc. Nonseparation assay methods
EP2068929A4 (en) * 2006-09-15 2010-04-28 Life Science Pharmaceuticals METHOD OF DETECTING AND TREATING SKIN DISORDERS
US8173423B2 (en) 2006-11-07 2012-05-08 Vib Vzw Diagnosis and treatment of T-cell acute lymphoblastic leukemia
WO2009062027A1 (en) * 2007-11-07 2009-05-14 Beckman Coulter, Inc. Nonseparation assay methods using peroxide generating enzymes
US20100273189A1 (en) * 2009-02-27 2010-10-28 Beckman Coulter, Inc. Non separation assays with selective signal inhibitors
CA2753598C (en) * 2009-02-27 2018-07-10 Beckman Coulter, Inc. Solution phase homogeneous assays
US20110097723A1 (en) * 2009-09-19 2011-04-28 Qun Liu Methods and reagents for analyte detection
EP2535027B1 (en) 2011-06-17 2022-08-17 The Procter & Gamble Company Absorbent article having improved absorption properties
GB2510285B (en) 2011-11-21 2018-12-12 Procter & Gamble Absorbent articles with improved absorption properties
CN104761584A (zh) * 2015-02-27 2015-07-08 北京利德曼生化股份有限公司 吖啶酯衍生物及其合成方法和应用
EP3821249B1 (en) 2018-07-13 2022-06-29 3M Innovative Properties Company Specific binding chemiluminescent assay
US12379379B2 (en) 2018-07-13 2025-08-05 Neogen Food Safety Us Holdco Corporation Assay
CN115433229B (zh) * 2022-08-29 2025-07-25 长沙创新药物工业技术研究院有限公司 一种化学发光底物的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1327361C (en) * 1988-01-14 1994-03-01 Nihon Nohyaku Co., Ltd. Ketenedithioacetal derivative and processes for producing the same as well as a composition containing the same
EP0361470B1 (en) * 1988-09-30 1993-12-22 Fujirebio Inc. Method for the chemiluminescence assay of the activity of peroxidase
EP0422252B1 (en) * 1989-04-28 1995-07-26 Toray Industries, Inc. Method for detecting a substance using chemiluminescence
US5324835A (en) * 1990-03-30 1994-06-28 Biosensor Laboratories Co., Ltd. Pyridazinoquinoxalinones for use as chemiluminescent agents
US5491072A (en) * 1993-05-17 1996-02-13 Lumigen, Inc. N-alkylacridan carboxyl derivatives useful for chemiluminescent detection
US5648484A (en) * 1995-03-07 1997-07-15 Schering Corporation Catalytic enantioselective synthesis of a spriofused azetidinone
JP3169383B2 (ja) * 1996-01-16 2001-05-21 ルミゲン インク ホスファターゼ酵素で化学発光を生成させるための化合物、組成物および方法
US6126870A (en) * 1997-09-12 2000-10-03 Lumigen, Inc. Chemiluminescent labeling compounds

Also Published As

Publication number Publication date
US20040144948A1 (en) 2004-07-29
US20010039345A1 (en) 2001-11-08
US6891057B2 (en) 2005-05-10
WO1999014220A1 (en) 1999-03-25
JP2001516760A (ja) 2001-10-02
CA2300071C (en) 2009-04-07
EP1015461A1 (en) 2000-07-05
EP1015461A4 (en) 2001-07-11
JP4431272B2 (ja) 2010-03-10
US6696569B2 (en) 2004-02-24
ATE266667T1 (de) 2004-05-15
DE69823845T2 (de) 2005-04-28
DE69823845D1 (de) 2004-06-17
CA2300071A1 (en) 1999-03-25
EP1015461B1 (en) 2004-05-12

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Legal Events

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MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted