ATE263160T1 - Tocotrienolchinon- zyklisierungsprodukte mit antihypercholesterin wirkung - Google Patents
Tocotrienolchinon- zyklisierungsprodukte mit antihypercholesterin wirkungInfo
- Publication number
- ATE263160T1 ATE263160T1 AT01969391T AT01969391T ATE263160T1 AT E263160 T1 ATE263160 T1 AT E263160T1 AT 01969391 T AT01969391 T AT 01969391T AT 01969391 T AT01969391 T AT 01969391T AT E263160 T1 ATE263160 T1 AT E263160T1
- Authority
- AT
- Austria
- Prior art keywords
- tocotrienolquinone
- antihypercholesterol
- effect
- sup
- cycling products
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/94—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Cardiology (AREA)
- Botany (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Furan Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10034233A DE10034233A1 (de) | 2000-07-14 | 2000-07-14 | Tocotrienolchinon-Cyclisierungsprodukte |
PCT/EP2001/008163 WO2002006261A1 (de) | 2000-07-14 | 2001-07-13 | Tocotrienolchinon-zyklisierungsprodukte mit antihypercholesterin wirkung |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE263160T1 true ATE263160T1 (de) | 2004-04-15 |
Family
ID=7648895
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01969391T ATE263160T1 (de) | 2000-07-14 | 2001-07-13 | Tocotrienolchinon- zyklisierungsprodukte mit antihypercholesterin wirkung |
Country Status (10)
Country | Link |
---|---|
US (1) | US6977270B2 (de) |
EP (1) | EP1301501B1 (de) |
JP (1) | JP2004504313A (de) |
CN (1) | CN1441793A (de) |
AT (1) | ATE263160T1 (de) |
AU (1) | AU2001289659A1 (de) |
DE (2) | DE10034233A1 (de) |
DK (1) | DK1301501T3 (de) |
ES (1) | ES2218448T3 (de) |
WO (1) | WO2002006261A1 (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20120046237A1 (en) * | 1998-04-08 | 2012-02-23 | Theoharides Theoharis C | Compositions for protection against superficial vasodilator flush syndrome, and methods of use |
PL1888059T3 (pl) | 2005-06-01 | 2015-06-30 | Bioelectron Tech Corp | Środki terapeutyczne aktywne wobec układów redoks do leczenia chorób mitochondrialnych i innych zaburzeń oraz modulacja biomarkerów energetycznych |
WO2007035496A1 (en) * | 2005-09-15 | 2007-03-29 | Edison Pharmaceuticals, Inc. | Tail variants of redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers |
JP5374162B2 (ja) | 2006-02-22 | 2013-12-25 | エジソン ファーマシューティカルズ, インコーポレイテッド | ミトコンドリア病および他の症状の処置のためのレドックス活性化治療の側鎖変異体およびエネルギーバイオマーカーの調節 |
MX2011002318A (es) | 2008-09-10 | 2011-05-10 | Edison Pharmaceuticals Inc | Tratamiento de trastornos generalizados del desarrollo con terapeuticos con actividad redox. |
PT2963006T (pt) * | 2008-10-28 | 2018-12-14 | Bioelectron Tech Corp | Composição contendo alfa-tocotrienol quinona e seus intermediários |
EP2424495B1 (de) | 2009-04-28 | 2018-01-17 | Bioelectron Technology Corporation | Behandlung von erblicher leber-optikus-neuropathie und dominanter optikus-neuropathie mit tocotrienol-chinonen |
SI2470168T1 (en) * | 2009-08-26 | 2018-05-31 | Bioelectron Technology Corporation | Procedures for the prevention and treatment of brain ischemia |
WO2013013078A1 (en) | 2011-07-19 | 2013-01-24 | Edison Pharmeceuticals, Inc. | Methods for selective oxidation of alpha tocotrienol in the presence of non-alpha tocotrienols |
ES2700983T3 (es) | 2012-06-08 | 2019-02-20 | Univ Ohio State | Tratamiento de lesión cicatricial usando tocotrienol |
WO2017106786A1 (en) | 2015-12-16 | 2017-06-22 | Bioelectron Technology Corporation | Improved methods for enriching alpha-tocotrienol from mixed tocol compositions |
CA3008849A1 (en) | 2015-12-17 | 2017-06-22 | Bioelectron Technology Corporation | Flouroalkyl, flouroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5217992A (en) * | 1989-10-04 | 1993-06-08 | Bristol-Myers Squibb Company | Tocotrienols in the treatment of hypercholesterolemia, hyperlipidemia and thromboembolic disorders |
KR910007523A (ko) * | 1989-10-04 | 1991-05-30 | 브리스톨-마이어즈 스퀴브 컴페니 | 과콜레스테린혈증, 과지방혈증 및 혈전색전증 질병 치료용 토코트리엔올 |
CA2050514A1 (en) * | 1990-09-14 | 1992-03-15 | Bradley C. Pearce | Acyclic tocotrienol analogs in the treatment of hypercholesterolemia and hyperlipidemia |
CA2096496A1 (en) * | 1992-05-29 | 1993-11-30 | Bradley C. Pearce | Acyclic tocotrienol analogs in the treatment of hypercholesterolemia and hyperlipidemia |
US5318993A (en) * | 1993-04-16 | 1994-06-07 | Bristol-Myers Squibb Company | Antihyperlipidemic benzoquinones |
EP0669132A1 (de) * | 1994-02-23 | 1995-08-30 | van der Kraaij, Antonius Marinus Maria | Kombinationspräparat von Vitamine E und Acetylsalicylate zur Behandlung und Prophylaxis des Atherosclerosis |
JP3926888B2 (ja) | 1997-05-27 | 2007-06-06 | 株式会社カネカ | コレステロール低下剤 |
-
2000
- 2000-07-14 DE DE10034233A patent/DE10034233A1/de not_active Withdrawn
-
2001
- 2001-07-13 AT AT01969391T patent/ATE263160T1/de not_active IP Right Cessation
- 2001-07-13 DK DK01969391T patent/DK1301501T3/da active
- 2001-07-13 ES ES01969391T patent/ES2218448T3/es not_active Expired - Lifetime
- 2001-07-13 WO PCT/EP2001/008163 patent/WO2002006261A1/de active IP Right Grant
- 2001-07-13 AU AU2001289659A patent/AU2001289659A1/en not_active Abandoned
- 2001-07-13 EP EP01969391A patent/EP1301501B1/de not_active Expired - Lifetime
- 2001-07-13 CN CN01812696A patent/CN1441793A/zh active Pending
- 2001-07-13 JP JP2002512165A patent/JP2004504313A/ja not_active Withdrawn
- 2001-07-13 US US10/332,863 patent/US6977270B2/en not_active Expired - Lifetime
- 2001-07-13 DE DE50101861T patent/DE50101861D1/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ES2218448T3 (es) | 2004-11-16 |
AU2001289659A1 (en) | 2002-01-30 |
US20040116715A1 (en) | 2004-06-17 |
WO2002006261A1 (de) | 2002-01-24 |
EP1301501B1 (de) | 2004-03-31 |
DE50101861D1 (de) | 2004-05-06 |
CN1441793A (zh) | 2003-09-10 |
DK1301501T3 (da) | 2004-07-19 |
EP1301501A1 (de) | 2003-04-16 |
JP2004504313A (ja) | 2004-02-12 |
US6977270B2 (en) | 2005-12-20 |
DE10034233A1 (de) | 2002-01-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
REN | Ceased due to non-payment of the annual fee |