ATE262038T1 - Br96 mutantantikörper die mit menschlichen karzinomen reagieren - Google Patents
Br96 mutantantikörper die mit menschlichen karzinomen reagierenInfo
- Publication number
- ATE262038T1 ATE262038T1 AT95305444T AT95305444T ATE262038T1 AT E262038 T1 ATE262038 T1 AT E262038T1 AT 95305444 T AT95305444 T AT 95305444T AT 95305444 T AT95305444 T AT 95305444T AT E262038 T1 ATE262038 T1 AT E262038T1
- Authority
- AT
- Austria
- Prior art keywords
- react
- mutant antibodies
- human carcinoma
- variable region
- mutant
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/285,936 US5728821A (en) | 1994-08-04 | 1994-08-04 | Mutant BR96 antibodies reactive with human carcinomas |
US08/487,860 US5792456A (en) | 1994-08-04 | 1995-06-07 | Mutant BR96 antibodies reactive with human carcinomas |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE262038T1 true ATE262038T1 (de) | 2004-04-15 |
Family
ID=26963478
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT95305444T ATE262038T1 (de) | 1994-08-04 | 1995-08-03 | Br96 mutantantikörper die mit menschlichen karzinomen reagieren |
Country Status (9)
Country | Link |
---|---|
US (1) | US5792456A (de) |
EP (1) | EP0699756B1 (de) |
JP (1) | JPH08191692A (de) |
AT (1) | ATE262038T1 (de) |
AU (1) | AU2834995A (de) |
CA (1) | CA2155397A1 (de) |
DE (1) | DE69532701D1 (de) |
IL (1) | IL114809A0 (de) |
MX (1) | MX9503362A (de) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6247995B1 (en) | 1996-02-06 | 2001-06-19 | Bruce Bryan | Bioluminescent novelty items |
US7247302B1 (en) * | 1996-08-02 | 2007-07-24 | Bristol-Myers Squibb Company | Method for inhibiting immunoglobulin-induced toxicity resulting from the use of immunoglobulins in therapy and in vivo diagnosis |
AU3968897A (en) * | 1996-08-02 | 1998-02-25 | Bristol-Myers Squibb Company | A method for inhibiting immunoglobulin-induced toxicity resulting from the use of immunoglobulins in therapy and in vivo diagnosis |
US6416960B1 (en) | 1996-08-08 | 2002-07-09 | Prolume, Ltd. | Detection and visualization of neoplastic tissues and other tissues |
ATE290205T1 (de) | 1996-12-12 | 2005-03-15 | Prolume Ltd | Vorrichtung und verfahren zum nachweis und identifizieren von infektiösen wirkstoffen |
EP1007967A2 (de) * | 1997-08-04 | 2000-06-14 | Ixsys, Incorporated | Verfahren zur identifizierung ligandspezifischer bindungsmoleküle |
AUPP221098A0 (en) * | 1998-03-06 | 1998-04-02 | Diatech Pty Ltd | V-like domain binding molecules |
US20040009535A1 (en) | 1998-11-27 | 2004-01-15 | Celltech R&D, Inc. | Compositions and methods for increasing bone mineralization |
US6656467B2 (en) | 2000-01-27 | 2003-12-02 | Medimmune, Inc. | Ultra high affinity neutralizing antibodies |
DK1259547T3 (da) | 2000-03-01 | 2012-10-15 | Medimmune Inc | Højpotente, rekombinante antistoffer og fremgangsmåde til fremstilling heraf |
US6599441B1 (en) * | 2000-07-18 | 2003-07-29 | Emerald Biostructures, Inc. | Crystallization solutions |
US7179900B2 (en) | 2000-11-28 | 2007-02-20 | Medimmune, Inc. | Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment |
JP2005502645A (ja) * | 2001-08-08 | 2005-01-27 | ザ ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム | 細胞特異的プロモーターからの発現を増幅するための方法 |
US7132100B2 (en) | 2002-06-14 | 2006-11-07 | Medimmune, Inc. | Stabilized liquid anti-RSV antibody formulations |
AT413487B (de) * | 2002-08-12 | 2006-03-15 | Igeneon Krebs Immuntherapie | Verwendung von antikörpern gegen ein tumor-assoziiertes antigen |
JP4462964B2 (ja) * | 2003-03-10 | 2010-05-12 | 第一三共株式会社 | 癌特異的抗原を標的とした抗体 |
AR048098A1 (es) * | 2004-03-15 | 2006-03-29 | Wyeth Corp | Conjugados de caliqueamicina |
EP1943332A4 (de) * | 2005-10-14 | 2011-04-13 | Medimmune Inc | Zellpräsentation von antikörperbibliotheken |
US8377448B2 (en) * | 2006-05-15 | 2013-02-19 | The Board Of Trustees Of The Leland Standford Junior University | CD47 related compositions and methods for treating immunological diseases and disorders |
US20080131431A1 (en) * | 2006-05-15 | 2008-06-05 | Viral Logic Systems Technology Corp. | CD47 related compositions and methods for treating immunological diseases and disorders |
US7858752B2 (en) * | 2006-12-05 | 2010-12-28 | Abbott Laboratories | Recombinant antibodies against hepatitis C virus and methods of obtaining and using same |
EP1997830A1 (de) | 2007-06-01 | 2008-12-03 | AIMM Therapeutics B.V. | RSV-spezifische Bindemoleküle und Mittel zu ihrer Herstellung |
US8568726B2 (en) | 2009-10-06 | 2013-10-29 | Medimmune Limited | RSV specific binding molecule |
UY34317A (es) | 2011-09-12 | 2013-02-28 | Genzyme Corp | Anticuerpo antireceptor de célula T (alfa)/ß |
BR112015020885A2 (pt) | 2013-03-11 | 2017-10-10 | Genzyme Corp | polipeptídeos de ligação hiperglicosilados |
EP3129067B1 (de) | 2014-03-19 | 2023-01-04 | Genzyme Corporation | Ortsspezifisches glycoengineering von targeting-teilen |
SG11202010025YA (en) | 2018-05-31 | 2020-11-27 | Glyconex Inc | Therapeutic antibodies binding to biantennary lewis b and lewis y antigens |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4474893A (en) * | 1981-07-01 | 1984-10-02 | The University of Texas System Cancer Center | Recombinant monoclonal antibodies |
US4713352A (en) * | 1981-08-31 | 1987-12-15 | Sloan-Kettering Institute For Cancer Reseach | Monoclonal antibody panel for early diagnosis and therapy of renal carcinoma |
US4612282A (en) * | 1981-12-15 | 1986-09-16 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Monoclonal antibodies reactive with human breast cancer |
US4507391A (en) * | 1982-04-02 | 1985-03-26 | Sloan-Kettering Institute For Cancer Research | Method for detecting the presence of GD3 ganglioside |
US4713351A (en) * | 1983-01-28 | 1987-12-15 | The University Of Rochester | Monoclonal antibody directed to an antigen derived from human ovarian tumors and a radioimmunoassay using the antibody |
US4579827A (en) * | 1983-03-11 | 1986-04-01 | Sloan-Kettering Institute For Cancer Research | Monoclonal antibodies to human gastrointestinal cancers and hybridoma method of production of the monoclonal antibodies |
US4753894A (en) * | 1984-02-08 | 1988-06-28 | Cetus Corporation | Monoclonal anti-human breast cancer antibodies |
ZA858371B (en) * | 1984-11-02 | 1987-03-25 | Oncogen | Monoclonal antibodies for human non-small cell lung carcinomas |
US4708930A (en) * | 1984-11-09 | 1987-11-24 | Coulter Corporation | Monoclonal antibody to a human carcinoma tumor associated antigen |
US4676980A (en) * | 1985-09-23 | 1987-06-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Target specific cross-linked heteroantibodies |
PT89107A (pt) * | 1987-11-30 | 1989-11-30 | Idec Pharma Corp | Metodo e meios para a seleccao de anticorpos anti-idiotipos e seu uso para o diagnostico, monitorizacao, tratamento e/ou prevencao de doencas cancerosas, da autoimunidade ou infecciosas |
IL94872A (en) * | 1989-06-30 | 1995-03-30 | Oncogen | Monoclonal or chimeric antibodies that react with human carcinoma, recombinant proteins that contain their anti-binding site, pharmaceutical preparations and kits that contain the |
JPH06501705A (ja) * | 1990-11-05 | 1994-02-24 | ブリストル−マイアーズ スクイブ カンパニー | 抗−腫瘍抗体及び生物学的活性剤の組合せによる相乗治療 |
ATE239506T1 (de) * | 1992-03-05 | 2003-05-15 | Univ Texas | Verwendung von immunokonjugate zur diagnose und/oder therapie der vaskularisierten tumoren |
-
1995
- 1995-06-07 US US08/487,860 patent/US5792456A/en not_active Expired - Fee Related
- 1995-08-02 IL IL11480995A patent/IL114809A0/xx unknown
- 1995-08-03 EP EP95305444A patent/EP0699756B1/de not_active Expired - Lifetime
- 1995-08-03 CA CA002155397A patent/CA2155397A1/en not_active Abandoned
- 1995-08-03 AT AT95305444T patent/ATE262038T1/de not_active IP Right Cessation
- 1995-08-03 DE DE69532701T patent/DE69532701D1/de not_active Expired - Lifetime
- 1995-08-03 AU AU28349/95A patent/AU2834995A/en not_active Abandoned
- 1995-08-04 JP JP7230629A patent/JPH08191692A/ja active Pending
- 1995-08-04 MX MX9503362A patent/MX9503362A/es unknown
Also Published As
Publication number | Publication date |
---|---|
US5792456A (en) | 1998-08-11 |
DE69532701D1 (de) | 2004-04-22 |
IL114809A0 (en) | 1995-12-08 |
JPH08191692A (ja) | 1996-07-30 |
CA2155397A1 (en) | 1996-02-05 |
MX9503362A (es) | 1997-08-30 |
AU2834995A (en) | 1996-02-15 |
EP0699756A1 (de) | 1996-03-06 |
EP0699756B1 (de) | 2004-03-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |