ATE25850T1 - Derivate von amiden. - Google Patents

Derivate von amiden.

Info

Publication number
ATE25850T1
ATE25850T1 AT83300169T AT83300169T ATE25850T1 AT E25850 T1 ATE25850 T1 AT E25850T1 AT 83300169 T AT83300169 T AT 83300169T AT 83300169 T AT83300169 T AT 83300169T AT E25850 T1 ATE25850 T1 AT E25850T1
Authority
AT
Austria
Prior art keywords
amino
hydrogen
aryl
carbonyl
hydroxy
Prior art date
Application number
AT83300169T
Other languages
English (en)
Inventor
John Preston
William Robert Carling
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Plc filed Critical Ici Plc
Application granted granted Critical
Publication of ATE25850T1 publication Critical patent/ATE25850T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/80—Antihypertensive peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Furan Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Hydrogenated Pyridines (AREA)
AT83300169T 1982-01-22 1983-01-13 Derivate von amiden. ATE25850T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8201832 1982-01-22
EP83300169A EP0084941B1 (de) 1982-01-22 1983-01-13 Derivate von Amiden

Publications (1)

Publication Number Publication Date
ATE25850T1 true ATE25850T1 (de) 1987-03-15

Family

ID=10527812

Family Applications (1)

Application Number Title Priority Date Filing Date
AT83300169T ATE25850T1 (de) 1982-01-22 1983-01-13 Derivate von amiden.

Country Status (17)

Country Link
US (1) US4528282A (de)
EP (1) EP0084941B1 (de)
JP (1) JPS58134075A (de)
AT (1) ATE25850T1 (de)
AU (1) AU563149B2 (de)
DE (1) DE3370159D1 (de)
DK (1) DK23883A (de)
ES (2) ES525685A0 (de)
FI (1) FI830186L (de)
GR (1) GR77061B (de)
HU (1) HU189637B (de)
IE (1) IE54551B1 (de)
IL (1) IL67705A0 (de)
NO (1) NO830203L (de)
NZ (1) NZ203063A (de)
PT (1) PT76130A (de)
ZA (1) ZA83273B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986000896A1 (en) * 1984-07-30 1986-02-13 Schering Corporation NOVEL PROCESS FOR THE PREPARATION OF CIS, ENDOOCTAHYDROCYCLOPENTA ADb BDPYRROLE-2-CARBOXYLATE
FR2573765B1 (fr) * 1984-11-23 1988-06-10 Solvay Procede pour la synthese de peptides
HU192914B (en) * 1985-02-11 1987-07-28 Richter Gedeon Vegyeszet Process for producing new 3-/substituted amino/-5-phenyl-2/3h/-furanone derivatives and pharmaceutically acceptable salts
ES2051702T3 (es) * 1986-04-01 1994-07-01 Wako Pure Chem Ind Ltd Derivados peptidicos y metodo para medir la actividad de sustancias fisiologicamente activas usandolos como sustratos.
AT395012B (de) * 1986-06-27 1992-08-25 Richter Gedeon Vegyeszet Verfahren zur herstellung von n-(1(s)|thoxycarbonyl-3-phenyl-propyl)-(s)-alanyl-(s)prolin und von dessen saeureadditionssalzen
US5559256A (en) * 1992-07-20 1996-09-24 E. R. Squibb & Sons, Inc. Aminediol protease inhibitors
ATE282602T1 (de) * 1996-08-16 2004-12-15 Warner Lambert Co Buttersäure matrix-metalloproteinase-inhibitoren
TR200101663T2 (tr) 1998-12-10 2001-11-21 F.Hoffmann-La Roche Ag Pro-kollajen c-proteinaz inhibitörleri
WO2004067509A1 (ja) * 2003-01-31 2004-08-12 Sanwa Kagaku Kenkyusho Co., Ltd. ジペプチジルペプチダーゼivを阻害する化合物

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL58849A (en) * 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
US4303583A (en) * 1979-08-13 1981-12-01 American Home Products Corporation 1H,5H-[1,4]Thiazepino[4,3-a]indole-1,5-diones
US4350704A (en) * 1980-10-06 1982-09-21 Warner-Lambert Company Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic acids
US4350633A (en) * 1980-07-01 1982-09-21 American Home Products Corporation N-(2-Substituted-1-oxoalkyl)-2,3-dihydro-1H-indole-2-carboxylic acid derivatives
EP0048159A3 (de) * 1980-09-17 1982-05-12 University Of Miami Carboxyalkyl-Peptide und Thioäther und Äther von Peptiden als antihypertensive Mittel
US4344949A (en) * 1980-10-03 1982-08-17 Warner-Lambert Company Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
FR2492381A1 (fr) * 1980-10-21 1982-04-23 Science Union & Cie Nouveaux acides aza bicyclo alcane carboxyliques substitues leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme
US4296110A (en) * 1980-10-28 1981-10-20 E. I. Du Pont De Nemours And Company Antihypertensive I-substituted cyclic lactam-2-carboxylic acids
US4390700A (en) * 1980-11-10 1983-06-28 Ciba-Geigy Corporation 1-Carboxyazaalkanoyl-tetrahydroquinoline-2-carboxylic acids
US4425355A (en) * 1981-02-17 1984-01-10 Warner-Lambert Company Substituted acyl derivatives of chair form of octahydro-1H-indole-2-carboxylic acids
US4402969A (en) * 1981-03-23 1983-09-06 Merck & Co., Inc. Antihypertensive proline derivatives
US4374246A (en) * 1981-06-18 1983-02-15 Norwich Eaton Pharmaceuticals, Inc. 1-N-[(1-Carboxy-3-phenylpropyl)glycyl]-1,2,3,4-tetrahydroquinoline-2-carboxylic acid compounds
US4410520A (en) * 1981-11-09 1983-10-18 Ciba-Geigy Corporation 3-Amino-[1]-benzazepin-2-one-1-alkanoic acids
US4370494A (en) * 1982-01-15 1983-01-25 Norwich Eaton Pharmaceuticals, Inc. Converting enzyme inhibitors

Also Published As

Publication number Publication date
ES525684A0 (es) 1985-07-01
FI830186A7 (fi) 1983-07-23
ES8506272A1 (es) 1985-07-01
FI830186L (fi) 1983-07-23
IE54551B1 (en) 1989-11-22
IL67705A0 (en) 1983-05-15
GR77061B (de) 1984-09-05
EP0084941B1 (de) 1987-03-11
DE3370159D1 (en) 1987-04-16
AU1034183A (en) 1983-07-28
DK23883D0 (da) 1983-01-21
DK23883A (da) 1983-07-23
NZ203063A (en) 1985-12-13
ES8506271A1 (es) 1985-07-01
PT76130A (en) 1983-02-01
HU189637B (en) 1986-07-28
EP0084941A1 (de) 1983-08-03
US4528282A (en) 1985-07-09
AU563149B2 (en) 1987-07-02
NO830203L (no) 1983-07-25
JPS58134075A (ja) 1983-08-10
FI830186A0 (fi) 1983-01-20
ES525685A0 (es) 1985-07-01
IE830056L (en) 1983-07-22
ZA83273B (en) 1983-10-26

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee