ATE256166T1 - Verbindungen und verfahren zur herstellung von sulphoindocyaninfarbstoffen - Google Patents

Verbindungen und verfahren zur herstellung von sulphoindocyaninfarbstoffen

Info

Publication number
ATE256166T1
ATE256166T1 AT97938012T AT97938012T ATE256166T1 AT E256166 T1 ATE256166 T1 AT E256166T1 AT 97938012 T AT97938012 T AT 97938012T AT 97938012 T AT97938012 T AT 97938012T AT E256166 T1 ATE256166 T1 AT E256166T1
Authority
AT
Austria
Prior art keywords
dyes
sulphoindocyanine
intermediates
compounds
producing
Prior art date
Application number
AT97938012T
Other languages
English (en)
Inventor
Mark Norman Bobrow
Thomas Joseph Erickson
Original Assignee
Nen Life Science Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nen Life Science Prod Inc filed Critical Nen Life Science Prod Inc
Application granted granted Critical
Publication of ATE256166T1 publication Critical patent/ATE256166T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/02—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT97938012T 1996-07-26 1997-07-21 Verbindungen und verfahren zur herstellung von sulphoindocyaninfarbstoffen ATE256166T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/687,853 US5688966A (en) 1996-07-26 1996-07-26 Compounds and method for synthesizing sulfoindocyanine dyes
PCT/US1997/012797 WO1998004635A1 (en) 1996-07-26 1997-07-21 Compounds and method for synthesizing sulfoindocyanine dyes

Publications (1)

Publication Number Publication Date
ATE256166T1 true ATE256166T1 (de) 2003-12-15

Family

ID=24762139

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97938012T ATE256166T1 (de) 1996-07-26 1997-07-21 Verbindungen und verfahren zur herstellung von sulphoindocyaninfarbstoffen

Country Status (6)

Country Link
US (2) US5688966A (de)
EP (1) EP0882097B1 (de)
JP (2) JP3863920B2 (de)
AT (1) ATE256166T1 (de)
DE (1) DE69726709T2 (de)
WO (1) WO1998004635A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5741632A (en) * 1995-12-14 1998-04-21 Agfa-Gevaert, N.V. Class of non-sensitizing infra-red dyes for use in photosensitive elements
US5688966A (en) * 1996-07-26 1997-11-18 E. I. Du Pont De Nemours And Company Compounds and method for synthesizing sulfoindocyanine dyes
JPH11322800A (ja) * 1998-05-14 1999-11-24 Matsushita Electric Ind Co Ltd 色素標識タンパク質複合体およびその製造方法
US6307029B1 (en) 1996-11-08 2001-10-23 Matsushita Electric Industrial Co., Ltd. Dye-labeled protein conjugate and method for preparing the same
DE19824487A1 (de) 1998-06-02 1999-12-09 Bayer Ag Substituierte 3-Thiocarbamoylpyrazole
US6372937B1 (en) 1998-11-09 2002-04-16 Mark Norman Bobrow Enhanced catalyzed reporter deposition
US6114350A (en) * 1999-04-19 2000-09-05 Nen Life Science Products, Inc. Cyanine dyes and synthesis methods thereof
DE60126297T2 (de) 2000-09-29 2007-11-15 Molecular Probes, Inc., Eugene Modifizierte carbocyaninfarbstoffe und deren konjugate
WO2002068537A2 (en) * 2001-02-28 2002-09-06 Stratagene Fluorescent dye
US6617125B2 (en) 2001-06-29 2003-09-09 Perkinelmer Life Sciences, Inc. Compositions for enhanced catalyzed reporter deposition
US7091348B2 (en) * 2002-07-01 2006-08-15 Guava Technologies, Inc. Fluorescent dyes, energy transfer couples and methods
JP5639889B2 (ja) * 2007-09-18 2014-12-10 ダコ デンマーク アクティーゼルスカブ 生物学的標的の高速で高感度な検出方法
US8435735B2 (en) 2009-02-19 2013-05-07 Dako Denmark A/S Methods and compounds for detection of molecular targets
US8729276B2 (en) 2009-04-17 2014-05-20 Korea Institute Of Science And Technology Cyanine compound for labeling biomolecule and preparation method thereof
EP2491390B1 (de) 2009-10-20 2014-03-26 Dako Denmark A/S Immunochemischer nachweis von single-target-einheiten
CA2867144C (en) 2012-03-27 2019-07-02 Ventana Medical Systems, Inc. Signaling conjugates and methods of use
CN104704366B (zh) 2012-10-24 2018-06-19 贝克顿·迪金森公司 异羟肟酸取代的氮杂吲哚啉-花菁染料和它的生物共轭物
KR101953819B1 (ko) * 2017-12-22 2019-03-06 (주)바이오액츠 생체 분자 표지를 위한 신규 시아닌 화합물 및 그 제조방법

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4948882A (en) * 1983-02-22 1990-08-14 Syngene, Inc. Single-stranded labelled oligonucleotides, reactive monomers and methods of synthesis
JPS62123454A (ja) * 1985-08-08 1987-06-04 Fuji Photo Film Co Ltd ハロゲン化銀写真感光材料
US5268486A (en) * 1986-04-18 1993-12-07 Carnegie-Mellon Unversity Method for labeling and detecting materials employing arylsulfonate cyanine dyes
DE3912046B4 (de) * 1988-09-02 2004-03-25 Carnegie Mellon University Verfahren zum Markieren einer Komponente einer wäßrigen Flüssigkeit und lumineszenzphotostabiles Reaktionsprodukt
US5196306A (en) * 1989-03-29 1993-03-23 E. I. Du Pont De Nemours And Company Method for the detection or quantitation of an analyte using an analyte dependent enzyme activation system
US4981977A (en) * 1989-06-09 1991-01-01 Carnegie-Mellon University Intermediate for and fluorescent cyanine dyes containing carboxylic acid groups
US5378634A (en) * 1992-08-20 1995-01-03 Matsushita Electric Industrial Co., Ltd. Labelling color for detecting methamphetamine
JPH06123740A (ja) * 1992-10-12 1994-05-06 Canon Inc 蛋白質標識用（メロ）シアニン色素、及び色素標識蛋白質
DE4445065A1 (de) * 1994-12-07 1996-06-13 Diagnostikforschung Inst Verfahren zur In-vivo-Diagnostik mittels NIR-Strahlung
US5688966A (en) * 1996-07-26 1997-11-18 E. I. Du Pont De Nemours And Company Compounds and method for synthesizing sulfoindocyanine dyes

Also Published As

Publication number Publication date
DE69726709D1 (de) 2004-01-22
EP0882097A1 (de) 1998-12-09
US5688966A (en) 1997-11-18
US5767287A (en) 1998-06-16
JP2007016038A (ja) 2007-01-25
EP0882097B1 (de) 2003-12-10
DE69726709T2 (de) 2004-10-07
JP2000503707A (ja) 2000-03-28
WO1998004635A1 (en) 1998-02-05
JP3863920B2 (ja) 2006-12-27

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Legal Events

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