ATE250030T1 - Peptidverbindungen mit mmp- und tnf-hemmender wirkung - Google Patents
Peptidverbindungen mit mmp- und tnf-hemmender wirkungInfo
- Publication number
- ATE250030T1 ATE250030T1 AT97915607T AT97915607T ATE250030T1 AT E250030 T1 ATE250030 T1 AT E250030T1 AT 97915607 T AT97915607 T AT 97915607T AT 97915607 T AT97915607 T AT 97915607T AT E250030 T1 ATE250030 T1 AT E250030T1
- Authority
- AT
- Austria
- Prior art keywords
- pct
- compounds
- mmp
- subject invention
- peptide compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 230000002401 inhibitory effect Effects 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 108010092694 L-Selectin Proteins 0.000 abstract 2
- 102000016551 L-selectin Human genes 0.000 abstract 2
- 102000002274 Matrix Metalloproteinases Human genes 0.000 abstract 2
- 108010000684 Matrix Metalloproteinases Proteins 0.000 abstract 2
- 230000001404 mediated effect Effects 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/20—Esters of monothiocarboxylic acids
- C07C327/32—Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9607249.1A GB9607249D0 (en) | 1996-04-04 | 1996-04-04 | Compounds |
| PCT/GB1997/000959 WO1997037974A1 (en) | 1996-04-04 | 1997-04-04 | Peptidyl compounds having mmp and tnf inhibitory activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE250030T1 true ATE250030T1 (de) | 2003-10-15 |
Family
ID=10791700
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97915607T ATE250030T1 (de) | 1996-04-04 | 1997-04-04 | Peptidverbindungen mit mmp- und tnf-hemmender wirkung |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6090840A (de) |
| EP (1) | EP0891329B1 (de) |
| JP (1) | JP2000508640A (de) |
| AT (1) | ATE250030T1 (de) |
| AU (1) | AU713477B2 (de) |
| CA (1) | CA2248070A1 (de) |
| DE (1) | DE69724944T2 (de) |
| GB (1) | GB9607249D0 (de) |
| WO (1) | WO1997037974A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040122011A1 (en) * | 1998-12-23 | 2004-06-24 | Pharmacia Corporation | Method of using a COX-2 inhibitor and a TACE inhibitors as a combination therapy |
| FR2797890A1 (fr) * | 1999-08-31 | 2001-03-02 | Pf Medicament | Nouvelle metalloprotease matricielle mmp-24 homologue aux stromelysines |
| US6808902B1 (en) | 1999-11-12 | 2004-10-26 | Amgen Inc. | Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules |
| CA2451955C (en) | 2001-06-26 | 2015-09-29 | Abgenix, Inc. | Antibodies to opgl |
| US20040225077A1 (en) | 2002-12-30 | 2004-11-11 | Angiotech International Ag | Drug delivery from rapid gelling polymer composition |
| EP2041181B1 (de) * | 2006-06-08 | 2011-05-18 | Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) | Spezifische proteaseinhibitoren und ihre verwendung in der krebstherapie |
| PL3609877T3 (pl) * | 2017-04-14 | 2021-06-28 | Cosma S.P.A. | Sposób syntezy firokoksybu |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9323165D0 (en) * | 1993-11-10 | 1994-01-05 | Chiros Ltd | Compounds |
-
1996
- 1996-04-04 GB GBGB9607249.1A patent/GB9607249D0/en active Pending
-
1997
- 1997-04-04 CA CA002248070A patent/CA2248070A1/en not_active Abandoned
- 1997-04-04 DE DE69724944T patent/DE69724944T2/de not_active Expired - Fee Related
- 1997-04-04 EP EP97915607A patent/EP0891329B1/de not_active Expired - Lifetime
- 1997-04-04 AU AU23025/97A patent/AU713477B2/en not_active Ceased
- 1997-04-04 WO PCT/GB1997/000959 patent/WO1997037974A1/en not_active Ceased
- 1997-04-04 US US09/155,696 patent/US6090840A/en not_active Expired - Fee Related
- 1997-04-04 JP JP9535963A patent/JP2000508640A/ja active Pending
- 1997-04-04 AT AT97915607T patent/ATE250030T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0891329A1 (de) | 1999-01-20 |
| EP0891329B1 (de) | 2003-09-17 |
| AU713477B2 (en) | 1999-12-02 |
| DE69724944D1 (de) | 2003-10-23 |
| JP2000508640A (ja) | 2000-07-11 |
| AU2302597A (en) | 1997-10-29 |
| CA2248070A1 (en) | 1997-10-16 |
| GB9607249D0 (en) | 1996-06-12 |
| US6090840A (en) | 2000-07-18 |
| WO1997037974A1 (en) | 1997-10-16 |
| DE69724944T2 (de) | 2004-07-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FI961976A0 (fi) | Peptidyyliyhdisteitä ja niiden terapeuttinen käyttö metalloproteinaasien inhibiittoreina | |
| EP1119362A4 (de) | Verwendungsmethode von tetracyclinverbindungen zur steigerung der interleukin-10 produktion | |
| BG104996A (en) | Indole derivatives and their use in the treatment of malignant and other diseases caused by pathological cell proliferation | |
| GEP20063885B (en) | Indazole compounds and pharmaceutical compositions for inhibiting protein kinases, and methods for their use | |
| BG102644A (bg) | Подобрени концентрирани инжекционни и инфузионниразтвори за интравазално прилагане | |
| EA200000871A1 (ru) | Ингибиторы фосфолипазных ферментов | |
| EP1163208A4 (de) | Caspase inhibitoren und deren verwendung | |
| DE69729007D1 (de) | Hydroxamsäure- und carbonsäure-derivate mit mmp und tnf hemmender wirkung | |
| FI943805A0 (fi) | Substituoituja adeniinijohdannaisten käyttö multippeliskleroosin hoitoon | |
| UA26213C2 (uk) | Засіб для профілактики та лікуваhhя остеопорозу та фармацевтичhа композиція hа їх осhові | |
| MY119987A (en) | Antithrombotic agents. | |
| BR9811956B1 (pt) | naftiridinonas e composição farmacêutica compreendendo as mesmas. | |
| CY1111912T1 (el) | Μεθοδος αναστολης της δραστηριοτητας των οστεοκλαστων | |
| DK0682664T3 (da) | Forbindelser med både potent calciumantagonist og antioxiderende aktivitet og anvendelse deraf som cytobeskyttende midler | |
| ES2184077T3 (es) | Nuevas fenantridinas sustituidas en la posicion 6. | |
| BR9811099A (pt) | Inibidores de urocinase | |
| ATE169445T1 (de) | Verwendung von gelformulierungen als beizmittel | |
| NO20000784L (no) | Nye aggrecanaseinhibitorer og matriksmetalloproteinaser for behandling av artritt | |
| DE69724944D1 (de) | Peptidverbindungen mit mmp- und tnf-hemmender wirkung | |
| ATE309352T1 (de) | Inhibitoren der nf-kb aktivierung | |
| ES2175356T3 (es) | Uso de (+)-alfa-(2,3-dimetoxifenil)-1-[2-(4 fluorofenil)et il[-4- piperidinmetanol en el tratamiento de trastornos depresivos y trastornos bipolares. | |
| DE69724112D1 (de) | Peptidverbindungen mit mmp- und tnf-hemmender wirkung | |
| ATE208202T1 (de) | Verwendung von dimeticon zur behandlung der konstipation | |
| DE69424679D1 (de) | Zusammensetzung zur behandlung oder vorbeugung von herpes | |
| ATE236633T1 (de) | Topische verwendung von loperamid zur behandlung mikrobieller infektionen |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |