ATE250030T1 - Peptidverbindungen mit mmp- und tnf-hemmender wirkung - Google Patents
Peptidverbindungen mit mmp- und tnf-hemmender wirkungInfo
- Publication number
- ATE250030T1 ATE250030T1 AT97915607T AT97915607T ATE250030T1 AT E250030 T1 ATE250030 T1 AT E250030T1 AT 97915607 T AT97915607 T AT 97915607T AT 97915607 T AT97915607 T AT 97915607T AT E250030 T1 ATE250030 T1 AT E250030T1
- Authority
- AT
- Austria
- Prior art keywords
- pct
- compounds
- mmp
- subject invention
- peptide compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 230000002401 inhibitory effect Effects 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 108010092694 L-Selectin Proteins 0.000 abstract 2
- 102000016551 L-selectin Human genes 0.000 abstract 2
- 102000002274 Matrix Metalloproteinases Human genes 0.000 abstract 2
- 108010000684 Matrix Metalloproteinases Proteins 0.000 abstract 2
- 230000001404 mediated effect Effects 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/20—Esters of monothiocarboxylic acids
- C07C327/32—Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9607249.1A GB9607249D0 (en) | 1996-04-04 | 1996-04-04 | Compounds |
| PCT/GB1997/000959 WO1997037974A1 (en) | 1996-04-04 | 1997-04-04 | Peptidyl compounds having mmp and tnf inhibitory activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE250030T1 true ATE250030T1 (de) | 2003-10-15 |
Family
ID=10791700
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97915607T ATE250030T1 (de) | 1996-04-04 | 1997-04-04 | Peptidverbindungen mit mmp- und tnf-hemmender wirkung |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6090840A (de) |
| EP (1) | EP0891329B1 (de) |
| JP (1) | JP2000508640A (de) |
| AT (1) | ATE250030T1 (de) |
| AU (1) | AU713477B2 (de) |
| CA (1) | CA2248070A1 (de) |
| DE (1) | DE69724944T2 (de) |
| GB (1) | GB9607249D0 (de) |
| WO (1) | WO1997037974A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040122011A1 (en) * | 1998-12-23 | 2004-06-24 | Pharmacia Corporation | Method of using a COX-2 inhibitor and a TACE inhibitors as a combination therapy |
| FR2797890A1 (fr) * | 1999-08-31 | 2001-03-02 | Pf Medicament | Nouvelle metalloprotease matricielle mmp-24 homologue aux stromelysines |
| US6808902B1 (en) | 1999-11-12 | 2004-10-26 | Amgen Inc. | Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules |
| PH12012502440A1 (en) | 2001-06-26 | 2013-06-17 | Amgen Inc | Antibodies to opgl |
| EP2181704B1 (de) | 2002-12-30 | 2015-05-06 | Angiotech International Ag | Wirkstofffreisetzung von schnell gelierender Polymerzusammensetzung |
| ATE509956T1 (de) * | 2006-06-08 | 2011-06-15 | Helmholtz Zentrum Muenchen | Spezifische proteaseinhibitoren und ihre verwendung in der krebstherapie |
| US10807962B2 (en) * | 2017-04-14 | 2020-10-20 | Cosma S.P.A. | Process for the synthesis of firocoxib |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9323165D0 (en) * | 1993-11-10 | 1994-01-05 | Chiros Ltd | Compounds |
-
1996
- 1996-04-04 GB GBGB9607249.1A patent/GB9607249D0/en active Pending
-
1997
- 1997-04-04 DE DE69724944T patent/DE69724944T2/de not_active Expired - Fee Related
- 1997-04-04 CA CA002248070A patent/CA2248070A1/en not_active Abandoned
- 1997-04-04 US US09/155,696 patent/US6090840A/en not_active Expired - Fee Related
- 1997-04-04 AU AU23025/97A patent/AU713477B2/en not_active Ceased
- 1997-04-04 WO PCT/GB1997/000959 patent/WO1997037974A1/en not_active Ceased
- 1997-04-04 EP EP97915607A patent/EP0891329B1/de not_active Expired - Lifetime
- 1997-04-04 AT AT97915607T patent/ATE250030T1/de not_active IP Right Cessation
- 1997-04-04 JP JP9535963A patent/JP2000508640A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU713477B2 (en) | 1999-12-02 |
| US6090840A (en) | 2000-07-18 |
| GB9607249D0 (en) | 1996-06-12 |
| WO1997037974A1 (en) | 1997-10-16 |
| EP0891329A1 (de) | 1999-01-20 |
| CA2248070A1 (en) | 1997-10-16 |
| DE69724944D1 (de) | 2003-10-23 |
| DE69724944T2 (de) | 2004-07-15 |
| JP2000508640A (ja) | 2000-07-11 |
| EP0891329B1 (de) | 2003-09-17 |
| AU2302597A (en) | 1997-10-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |