ATE241968T1 - Sedativ hypnotische zusammensetzungen mit gesteuerter freisetzung und diesbezügliche verfahren - Google Patents

Sedativ hypnotische zusammensetzungen mit gesteuerter freisetzung und diesbezügliche verfahren

Info

Publication number
ATE241968T1
ATE241968T1 AT00961399T AT00961399T ATE241968T1 AT E241968 T1 ATE241968 T1 AT E241968T1 AT 00961399 T AT00961399 T AT 00961399T AT 00961399 T AT00961399 T AT 00961399T AT E241968 T1 ATE241968 T1 AT E241968T1
Authority
AT
Austria
Prior art keywords
sedative
hypnotic
compound
controlled
related methods
Prior art date
Application number
AT00961399T
Other languages
German (de)
English (en)
Inventor
D Bruce Campbell
W Jay Thiele
Original Assignee
Neurocrine Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurocrine Biosciences Inc filed Critical Neurocrine Biosciences Inc
Application granted granted Critical
Publication of ATE241968T1 publication Critical patent/ATE241968T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT00961399T 1999-08-26 2000-08-28 Sedativ hypnotische zusammensetzungen mit gesteuerter freisetzung und diesbezügliche verfahren ATE241968T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38444899A 1999-08-26 1999-08-26
PCT/US2000/023665 WO2001013895A2 (en) 1999-08-26 2000-08-28 Controlled-release sedative-hypnotic compositions and methods related thereto

Publications (1)

Publication Number Publication Date
ATE241968T1 true ATE241968T1 (de) 2003-06-15

Family

ID=23517364

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00961399T ATE241968T1 (de) 1999-08-26 2000-08-28 Sedativ hypnotische zusammensetzungen mit gesteuerter freisetzung und diesbezügliche verfahren

Country Status (9)

Country Link
EP (2) EP1352647A1 (enExample)
JP (1) JP2003507413A (enExample)
AT (1) ATE241968T1 (enExample)
AU (1) AU7335500A (enExample)
DE (1) DE60003194T2 (enExample)
DK (1) DK1206248T3 (enExample)
ES (1) ES2199857T3 (enExample)
PT (1) PT1206248E (enExample)
WO (1) WO2001013895A2 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050038042A1 (en) * 2002-11-15 2005-02-17 Jenet Codd Modified release composition comprising a short-acting hypnotic for treatment of sleep disorders
WO2005027877A1 (en) * 2003-09-15 2005-03-31 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
GB0423964D0 (en) * 2004-10-28 2004-12-01 Jagotec Ag Dosage form
US20070020333A1 (en) * 2005-07-20 2007-01-25 Chin-Chih Chiang Controlled release of hypnotic agents
EP1970056A1 (en) * 2007-03-15 2008-09-17 Polichem S.A. Time-specific delayed/pulsatile release dosage forms
EP2540294B1 (en) * 2010-02-22 2016-08-03 Daiichi Sankyo Company, Limited Sustained-release solid preparation for oral use
EP2540318B1 (en) 2010-02-22 2018-10-24 Daiichi Sankyo Company, Limited Sustained-release solid preparation for oral use
CN102670613A (zh) * 2011-03-16 2012-09-19 中国人民解放军军事医学科学院毒物药物研究所 用于改善茚地普隆溶出的药物组合物及其制备方法
WO2014034929A1 (ja) 2012-09-03 2014-03-06 第一三共株式会社 ヒドロモルフォン塩酸塩含有の経口用徐放性医薬組成物
BR112016017742A2 (pt) * 2014-02-06 2018-06-26 Sequential Medicine Limited composição e método auxiliares do sono

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4654347A (en) * 1983-06-23 1987-03-31 American Cyanamid Company Aryl and heteroaryl[[7-(3-disubstituted amino)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]methanones
US4948592A (en) * 1986-05-09 1990-08-14 Alza Corporation Pulsed drug delivery
HRP970493A2 (en) * 1996-09-23 1998-08-31 Wienman E. Phlips Oral delayed immediate release medical formulation and method for preparing the same
EP1064937A1 (en) * 1999-06-28 2001-01-03 Sanofi-Synthelabo Timed dual release dosage forms comprising a short acting hypnotic or a salt thereof
US6472528B1 (en) * 1999-08-10 2002-10-29 Neurocrine Biosciences, Inc. Synthesis of substituted pyrazolopyrimidines

Also Published As

Publication number Publication date
EP1352647A1 (en) 2003-10-15
PT1206248E (pt) 2003-11-28
EP1206248A2 (en) 2002-05-22
JP2003507413A (ja) 2003-02-25
DE60003194T2 (de) 2004-06-17
WO2001013895A3 (en) 2001-09-27
AU7335500A (en) 2001-03-19
DE60003194D1 (de) 2003-07-10
ES2199857T3 (es) 2004-03-01
DK1206248T3 (da) 2003-09-29
WO2001013895A2 (en) 2001-03-01
EP1206248B1 (en) 2003-06-04

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