ATE239077T1 - Erzeugung von diversität in kombinatorischen banken - Google Patents
Erzeugung von diversität in kombinatorischen bankenInfo
- Publication number
- ATE239077T1 ATE239077T1 AT98910631T AT98910631T ATE239077T1 AT E239077 T1 ATE239077 T1 AT E239077T1 AT 98910631 T AT98910631 T AT 98910631T AT 98910631 T AT98910631 T AT 98910631T AT E239077 T1 ATE239077 T1 AT E239077T1
- Authority
- AT
- Austria
- Prior art keywords
- ligands
- banks
- combinatory
- creating diversity
- phagemid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/66—General methods for inserting a gene into a vector to form a recombinant vector using cleavage and ligation; Use of non-functional linkers or adaptors, e.g. linkers containing the sequence for a restriction endonuclease
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97101539 | 1997-01-31 | ||
| PCT/EP1998/000533 WO1998033901A2 (en) | 1997-01-31 | 1998-02-02 | Generation of diversity in combinatorial libraries |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE239077T1 true ATE239077T1 (de) | 2003-05-15 |
Family
ID=8226431
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98910631T ATE239077T1 (de) | 1997-01-31 | 1998-02-02 | Erzeugung von diversität in kombinatorischen banken |
Country Status (11)
| Country | Link |
|---|---|
| EP (2) | EP1302540A3 (de) |
| JP (1) | JP2001509672A (de) |
| CN (1) | CN1246150A (de) |
| AT (1) | ATE239077T1 (de) |
| AU (1) | AU749249B2 (de) |
| CA (1) | CA2279341A1 (de) |
| DE (1) | DE69814059T2 (de) |
| DK (1) | DK0968283T3 (de) |
| ES (1) | ES2199431T3 (de) |
| IL (1) | IL131075A0 (de) |
| WO (1) | WO1998033901A2 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050191749A1 (en) * | 2000-12-08 | 2005-09-01 | Bowdish Katherine S. | Novel plasmid vectors |
| DE10145553B4 (de) * | 2001-09-16 | 2006-06-08 | Gene Architects Ag | Nukleinsäure für einen Klonierungsvektor |
| EP1384779A1 (de) * | 2002-07-26 | 2004-01-28 | Cosmix Molecular Biologicals GmbH | Methode zur Generierung von Molekülen mit spezifischen Eigenschaften durch Rekombination und Selektion |
| EP1384780A1 (de) * | 2002-07-26 | 2004-01-28 | Cosmix Molecular Biologicals GmbH | Methode zur Generierung von Molekülen mit spezifischen Eigenschaften durch Rekombination und Selektion |
| EP1398375A1 (de) * | 2002-09-13 | 2004-03-17 | Cosmix Molecular Biologicals GmbH | Recombinationsverfahren für Rekombination von verschiedenen Polynukleotidfragmenten |
| DE10337407A1 (de) * | 2003-08-13 | 2005-03-10 | Transmit Technologietransfer | Klonierungssystem |
| EP2940138B1 (de) | 2014-04-30 | 2018-02-28 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Phagen-Anzeigebibliothek |
| AU2017246593C1 (en) | 2016-04-08 | 2023-12-21 | Phico Therapeutics Ltd | Modified bacteriophage |
| CA3020371A1 (en) | 2016-04-08 | 2017-10-12 | Phico Therapeutics Ltd. | Modifying bacteriophage |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61132187A (ja) * | 1984-11-30 | 1986-06-19 | Banyu Pharmaceut Co Ltd | 新規コスミドベクタ−及びそれを用いる遺伝子バンクの製造方法 |
| IL99553A0 (en) * | 1990-09-28 | 1992-08-18 | Ixsys Inc | Compositions containing oligonucleotides linked to expression elements,a kit for the preparation of vectors useful for the expression of a diverse population of random peptides and methods utilizing the same |
| IL99552A0 (en) * | 1990-09-28 | 1992-08-18 | Ixsys Inc | Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof |
| FR2715940B1 (fr) * | 1994-02-10 | 1996-04-26 | Pasteur Merieux Serums Vacc | Procédé de préparation d'une banque multicombinatoire de vecteurs d'expression de gènes d'anticorps, banque et systèmes d'expression d'anticorps "coliclonaux" obtenus. |
| US5605793A (en) * | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
| EP0699750A1 (de) * | 1994-06-07 | 1996-03-06 | Gesellschaft für biotechnologische Forschung mbH (GBF) | Eine Sammling an Phagemiden, eine Sammling von Escherichia coli Zellen die diese Phagemide tragen, eine Sammling an Phagemid-Partikeln die daraus hergestellt würden und Phagemid-Partikel die durch dieses Verfahren erhalten würden |
| US5702892A (en) * | 1995-05-09 | 1997-12-30 | The United States Of America As Represented By The Department Of Health And Human Services | Phage-display of immunoglobulin heavy chain libraries |
-
1998
- 1998-02-02 ES ES98910631T patent/ES2199431T3/es not_active Expired - Lifetime
- 1998-02-02 WO PCT/EP1998/000533 patent/WO1998033901A2/en active IP Right Grant
- 1998-02-02 AT AT98910631T patent/ATE239077T1/de not_active IP Right Cessation
- 1998-02-02 EP EP02021507A patent/EP1302540A3/de not_active Withdrawn
- 1998-02-02 JP JP53254598A patent/JP2001509672A/ja not_active Withdrawn
- 1998-02-02 DK DK98910631T patent/DK0968283T3/da active
- 1998-02-02 CA CA002279341A patent/CA2279341A1/en not_active Abandoned
- 1998-02-02 DE DE69814059T patent/DE69814059T2/de not_active Expired - Fee Related
- 1998-02-02 AU AU64951/98A patent/AU749249B2/en not_active Ceased
- 1998-02-02 CN CN98802184.6A patent/CN1246150A/zh active Pending
- 1998-02-02 EP EP98910631A patent/EP0968283B1/de not_active Expired - Lifetime
- 1998-02-02 IL IL13107598A patent/IL131075A0/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1302540A3 (de) | 2003-11-05 |
| IL131075A0 (en) | 2001-01-28 |
| CA2279341A1 (en) | 1998-08-06 |
| DE69814059D1 (de) | 2003-06-05 |
| DK0968283T3 (da) | 2003-08-25 |
| JP2001509672A (ja) | 2001-07-24 |
| WO1998033901A9 (en) | 1999-08-05 |
| DE69814059T2 (de) | 2004-05-19 |
| ES2199431T3 (es) | 2004-02-16 |
| EP0968283B1 (de) | 2003-05-02 |
| EP0968283A2 (de) | 2000-01-05 |
| AU6495198A (en) | 1998-08-25 |
| AU749249B2 (en) | 2002-06-20 |
| WO1998033901A3 (en) | 1999-06-17 |
| CN1246150A (zh) | 2000-03-01 |
| EP1302540A2 (de) | 2003-04-16 |
| WO1998033901A2 (en) | 1998-08-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0968283 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |