ATE309351T1 - Einkettigen polypeptiden enthalten troponin i und troponin c - Google Patents

Einkettigen polypeptiden enthalten troponin i und troponin c

Info

Publication number
ATE309351T1
ATE309351T1 AT98958383T AT98958383T ATE309351T1 AT E309351 T1 ATE309351 T1 AT E309351T1 AT 98958383 T AT98958383 T AT 98958383T AT 98958383 T AT98958383 T AT 98958383T AT E309351 T1 ATE309351 T1 AT E309351T1
Authority
AT
Austria
Prior art keywords
troponin
chain polypeptides
single chain
polypeptides contain
linker peptide
Prior art date
Application number
AT98958383T
Other languages
English (en)
Inventor
Qinwei Shi
Qian-Li Song
Original Assignee
Spectral Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spectral Diagnostics Inc filed Critical Spectral Diagnostics Inc
Application granted granted Critical
Publication of ATE309351T1 publication Critical patent/ATE309351T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4716—Muscle proteins, e.g. myosin, actin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT98958383T 1997-12-18 1998-12-18 Einkettigen polypeptiden enthalten troponin i und troponin c ATE309351T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/993,380 US6077676A (en) 1997-12-18 1997-12-18 Single-chain polypeptides comprising troponin I and troponin C
PCT/IB1998/002095 WO1999031235A1 (en) 1997-12-18 1998-12-18 Single-chain polypeptides comprising troponin i and troponin c

Publications (1)

Publication Number Publication Date
ATE309351T1 true ATE309351T1 (de) 2005-11-15

Family

ID=25539476

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98958383T ATE309351T1 (de) 1997-12-18 1998-12-18 Einkettigen polypeptiden enthalten troponin i und troponin c

Country Status (9)

Country Link
US (1) US6077676A (de)
EP (1) EP1037976B1 (de)
JP (1) JP4328019B2 (de)
AT (1) ATE309351T1 (de)
AU (1) AU1444699A (de)
CA (1) CA2315282C (de)
DE (1) DE69832299T2 (de)
ES (1) ES2253835T3 (de)
WO (1) WO1999031235A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2756827B1 (fr) * 1996-12-05 1999-01-29 Pasteur Sanofi Diagnostics Composes synthetiques biepitopiques utilisables comme etalons dans les dosages biologiques de la troponine i
US6475785B1 (en) * 1997-12-18 2002-11-05 Spectral Diagnostics, Inc. Single-chain polypeptides comprising troponin I N-terminal fragments and troponin C
WO2000023585A1 (en) 1998-10-21 2000-04-27 Spectral Diagnostics, Inc. Cardiac troponin i polypeptide fragments and uses in diagnostics
US7078486B2 (en) * 1999-12-10 2006-07-18 Spectral Diagnostics, Inc. Single-chain polypeptides comprising troponin I and troponin C
US20070141710A1 (en) * 2005-12-20 2007-06-21 Beckman Coulter, Inc. Stable calibrators for immunoassays
US20110306148A1 (en) 2010-06-14 2011-12-15 Siemens Healthcare Diagnostics Inc. Composition for use as an assay reagent
CN107245103A (zh) * 2016-12-30 2017-10-13 广西壮族自治区药用植物园 抗肿瘤重组蛋白ifti及其编码基因与应用
CN107245102A (zh) * 2016-12-30 2017-10-13 广西壮族自治区药用植物园 抗肿瘤重组蛋白gpti及其编码基因与应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4892827A (en) * 1986-09-24 1990-01-09 The United States Of America As Represented By The Department Of Health And Human Services Recombinant pseudomonas exotoxins: construction of an active immunotoxin with low side effects
CA2027434C (en) * 1990-10-12 1999-01-05 George Jackowski Diagnostic kit for diagnosing and distinguishing chest pain in early onset thereof
US5604105B1 (en) * 1990-10-12 1999-08-24 Spectral Diagnostics Inc Method and device for diagnosingand distinguishing chest pain in early onset thereof
DE69334095T2 (de) * 1992-07-17 2007-04-12 Dana-Farber Cancer Institute, Boston Verfahren zur intrazellulären Bindung von zielgerichteten Molekülen
FR2701954B1 (fr) * 1993-02-23 1995-07-07 Pasteur Sanofi Diagnostics Composition stabilisée de troponine pour immunoessais et procédé de stabilisation de troponine pour immunoessais.
DE805821T1 (de) * 1995-11-29 1998-05-14 Dade Int Inc MENSCHLICHES HERZ-CNBr TROPONIN I-ISOFORM UND DESSEN VERWENDUNG
FI104857B (fi) * 1996-01-15 2000-04-14 Hytest Oy Sydänlihaksen soluvaurioiden asteen mittaus immunokemiallisella menetelmällä sisältäen menetelmään soveliaat vasta-aineet
WO1997039132A1 (en) * 1996-04-16 1997-10-23 University Of Miami Stabilized preparations of human troponins and modifications thereof, diagnostic assay methods and assay kits
US6072040A (en) * 1996-10-15 2000-06-06 Medical Analysis Systems, Inc. Stabilized conjugates of uncomplexed subunits of multimeric proteins
US5834210A (en) * 1997-05-23 1998-11-10 Spectral Diagnostics, Inc. Stable troponin subunits and complexes
EP0983299A1 (de) * 1997-05-29 2000-03-08 Medical Analysis Systems, Inc. Kovalent-gekoppelte troponinkomplexen

Also Published As

Publication number Publication date
CA2315282A1 (en) 1999-06-24
JP4328019B2 (ja) 2009-09-09
DE69832299T2 (de) 2006-08-10
US6077676A (en) 2000-06-20
EP1037976B1 (de) 2005-11-09
CA2315282C (en) 2012-10-23
DE69832299D1 (de) 2005-12-15
EP1037976A1 (de) 2000-09-27
ES2253835T3 (es) 2006-06-01
WO1999031235A1 (en) 1999-06-24
AU1444699A (en) 1999-07-05
JP2002508181A (ja) 2002-03-19

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Legal Events

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