DK0889957T3 - Subtilisindimer med forbedret aktivitet og fremgangsmåde til fremstilling deraf - Google Patents

Subtilisindimer med forbedret aktivitet og fremgangsmåde til fremstilling deraf

Info

Publication number
DK0889957T3
DK0889957T3 DK97906920T DK97906920T DK0889957T3 DK 0889957 T3 DK0889957 T3 DK 0889957T3 DK 97906920 T DK97906920 T DK 97906920T DK 97906920 T DK97906920 T DK 97906920T DK 0889957 T3 DK0889957 T3 DK 0889957T3
Authority
DK
Denmark
Prior art keywords
monomer unit
subtilisin
dimer
preparation
improved activity
Prior art date
Application number
DK97906920T
Other languages
English (en)
Inventor
Richard R Bott
Christian Paech
Shan Wu
Original Assignee
Genencor Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genencor Int filed Critical Genencor Int
Application granted granted Critical
Publication of DK0889957T3 publication Critical patent/DK0889957T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • D—TEXTILES; PAPER
    • D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
    • D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
    • D06M16/00—Biochemical treatment of fibres, threads, yarns, fabrics, or fibrous goods made from such materials, e.g. enzymatic
    • D06M16/003—Biochemical treatment of fibres, threads, yarns, fabrics, or fibrous goods made from such materials, e.g. enzymatic with enzymes or microorganisms
    • D—TEXTILES; PAPER
    • D21—PAPER-MAKING; PRODUCTION OF CELLULOSE
    • D21C—PRODUCTION OF CELLULOSE BY REMOVING NON-CELLULOSE SUBSTANCES FROM CELLULOSE-CONTAINING MATERIALS; REGENERATION OF PULPING LIQUORS; APPARATUS THEREFOR
    • D21C5/00—Other processes for obtaining cellulose, e.g. cooking cotton linters ; Processes characterised by the choice of cellulose-containing starting materials
    • D21C5/005—Treatment of cellulose-containing material with microorganisms or enzymes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Textile Engineering (AREA)
  • General Chemical & Material Sciences (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Detergent Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK97906920T 1996-03-29 1997-02-17 Subtilisindimer med forbedret aktivitet og fremgangsmåde til fremstilling deraf DK0889957T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/625,487 US6946280B1 (en) 1996-03-29 1996-03-29 Enzyme multimer and process of producing same

Publications (1)

Publication Number Publication Date
DK0889957T3 true DK0889957T3 (da) 2007-01-08

Family

ID=24506318

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97906920T DK0889957T3 (da) 1996-03-29 1997-02-17 Subtilisindimer med forbedret aktivitet og fremgangsmåde til fremstilling deraf

Country Status (13)

Country Link
US (3) US6946280B1 (da)
EP (1) EP0889957B1 (da)
JP (1) JP2000507452A (da)
CN (1) CN1215429A (da)
AT (1) ATE338112T1 (da)
AU (1) AU719263B2 (da)
BR (1) BR9708453A (da)
CA (1) CA2248649C (da)
DE (1) DE69736588T2 (da)
DK (1) DK0889957T3 (da)
ES (1) ES2267132T3 (da)
NZ (1) NZ332236A (da)
WO (1) WO1997037007A1 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6946280B1 (en) * 1996-03-29 2005-09-20 Genencor International, Inc. Enzyme multimer and process of producing same
EP1082442A1 (en) 1998-03-26 2001-03-14 The Procter & Gamble Company Serine protease variants having amino acid substitutions
US6908757B1 (en) 1998-03-26 2005-06-21 The Procter & Gamble Company Serine protease variants having amino acid deletions and substitutions
US6495136B1 (en) 1998-03-26 2002-12-17 The Procter & Gamble Company Proteases having modified amino acid sequences conjugated to addition moieties
EP1093459B1 (en) 1998-07-02 2008-09-10 The Governing Council Of The University Of Toronto Chemically modified proteins with a carbohydrate moiety
ATE433485T1 (de) 1998-11-10 2009-06-15 Univ Toronto Chemisch modifizierte mutante serinhydrolasen
JP2002533087A (ja) 1998-12-21 2002-10-08 ジェネンカー インターナショナル，インコーポレイティド 複数荷電変種を有する化学修飾酵素
CA2368213C (en) 1999-04-28 2013-08-06 Genencor International, Inc. Specifically targeted catalytic antagonists and uses thereof
US6627744B2 (en) 1999-07-02 2003-09-30 Genencor International, Inc. Synthesis of glycodendrimer reagents
CN1377406A (zh) 1999-07-22 2002-10-30 宝洁公司 具有空间保护的切割位点的蛋白酶缀合物
US6946128B1 (en) 1999-07-22 2005-09-20 The Procter & Gamble Company Protease conjugates having sterically protected epitope regions
MXPA02000840A (es) 1999-07-22 2002-07-30 Procter & Gamble Variantes de proteasa de subtilisina que tienen substituciones de aminoacidos en regiones de epitopes definidas.
AU777550B2 (en) * 1999-07-22 2004-10-21 Procter & Gamble Company, The Protease conjugates having sterically protected epitope regions
CA2379712A1 (en) 1999-07-22 2001-02-01 The Procter & Gamble Company Subtilisin protease variants having amino acid deletions and substitutions in defined epitope regions
TW593841B (en) * 2003-03-06 2004-06-21 Yuen Foong Yu Paper Mfg Co Ltd A plant nutrition formulated by recovery filtrate from plant fiber biopulping and method thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0155832A3 (en) * 1984-03-16 1987-08-19 Genentech, Inc. Stable proteins, methods for their construction, plasmids and other dna encoding them, cell cultures harboring such plasmids
US5185258A (en) * 1984-05-29 1993-02-09 Genencor International, Inc. Subtilisin mutants
US4844897A (en) * 1985-09-13 1989-07-04 Hiroshi Maeda Anti-tumor protease preparations
US4908773A (en) * 1987-04-06 1990-03-13 Genex Corporation Computer designed stabilized proteins and method for producing same
US4853871A (en) * 1987-04-06 1989-08-01 Genex Corporation Computer-based method for designing stablized proteins
EP0309746A1 (de) * 1987-09-08 1989-04-05 F. Hoffmann-La Roche Ag Antimalaria-Vakzine
US5340735A (en) * 1991-05-29 1994-08-23 Cognis, Inc. Bacillus lentus alkaline protease variants with increased stability
JPH06207941A (ja) * 1992-05-29 1994-07-26 Toray Ind Inc 非ａ非ｂ型肝炎の検査方法
DK132892D0 (da) * 1992-10-30 1992-10-30 Novo Nordisk As Proteiner
US5795761A (en) * 1996-01-11 1998-08-18 Rutgers, The State University Of New Jersey Mutants of 2,5-diketo-D-gluconic acid (2,5-DKG) reductase A
US6946280B1 (en) * 1996-03-29 2005-09-20 Genencor International, Inc. Enzyme multimer and process of producing same

Also Published As

Publication number Publication date
US20060084160A1 (en) 2006-04-20
CN1215429A (zh) 1999-04-28
EP0889957B1 (en) 2006-08-30
ATE338112T1 (de) 2006-09-15
US6946280B1 (en) 2005-09-20
CA2248649C (en) 2010-10-12
ES2267132T3 (es) 2007-03-01
DE69736588T2 (de) 2007-09-27
EP0889957A1 (en) 1999-01-13
NZ332236A (en) 2000-03-27
WO1997037007A1 (en) 1997-10-09
DE69736588D1 (de) 2006-10-12
AU2276997A (en) 1997-10-22
JP2000507452A (ja) 2000-06-20
AU719263B2 (en) 2000-05-04
US7329528B2 (en) 2008-02-12
BR9708453A (pt) 1999-08-03
CA2248649A1 (en) 1997-10-09
US20050170471A1 (en) 2005-08-04

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