ATE235897T1 - Arzneimittel in form parenenteral verabreichbarer lipidmikropartikel - Google Patents
Arzneimittel in form parenenteral verabreichbarer lipidmikropartikelInfo
- Publication number
- ATE235897T1 ATE235897T1 AT98929383T AT98929383T ATE235897T1 AT E235897 T1 ATE235897 T1 AT E235897T1 AT 98929383 T AT98929383 T AT 98929383T AT 98929383 T AT98929383 T AT 98929383T AT E235897 T1 ATE235897 T1 AT E235897T1
- Authority
- AT
- Austria
- Prior art keywords
- parenenterally
- administerable
- medicinal products
- lipid microparticles
- microparticles
- Prior art date
Links
- 239000011859 microparticle Substances 0.000 title abstract 2
- 150000002632 lipids Chemical class 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
- 206010057249 Phagocytosis Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 210000002540 macrophage Anatomy 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 230000008782 phagocytosis Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5123—Organic compounds, e.g. fats, sugars
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Nanotechnology (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT97MI001385A IT1292142B1 (it) | 1997-06-12 | 1997-06-12 | Composizione farmaceutica in forma di microparticelle lipidiche solide atte alla somministrazione parenterale |
| PCT/EP1998/003110 WO1998056362A1 (en) | 1997-06-12 | 1998-05-27 | Pharmaceutical composition in form of solid lipidic microparticles suitable to parenteral administration |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE235897T1 true ATE235897T1 (de) | 2003-04-15 |
Family
ID=11377349
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98929383T ATE235897T1 (de) | 1997-06-12 | 1998-05-27 | Arzneimittel in form parenenteral verabreichbarer lipidmikropartikel |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6238694B1 (enEXAMPLES) |
| EP (1) | EP0988031B1 (enEXAMPLES) |
| AT (1) | ATE235897T1 (enEXAMPLES) |
| AU (1) | AU7915898A (enEXAMPLES) |
| CA (1) | CA2294172C (enEXAMPLES) |
| DE (1) | DE69812936T2 (enEXAMPLES) |
| IT (1) | IT1292142B1 (enEXAMPLES) |
| WO (1) | WO1998056362A1 (enEXAMPLES) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1296914B1 (it) * | 1997-12-01 | 1999-08-03 | Maria Rosa Gasco | Composizione farmaceutica comprendente microparticelle atte al passaggio transmucosale ed al superamento della barriera |
| IT1303787B1 (it) | 1998-11-25 | 2001-02-23 | Maria Rosa Gasco | "nanosfere lipidiche solide atte ad una rapida internalizzazione nellecellule" |
| EP1246608A4 (en) * | 2000-01-05 | 2005-05-18 | Imarx Therapeutics Inc | PHARMACEUTICAL PREPARATIONS FOR THE ADMINISTRATION OF ACTIVE SUBSTANCES WITH LOW WATER SOLUBILITY |
| US7153525B1 (en) | 2000-03-22 | 2006-12-26 | The University Of Kentucky Research Foundation | Microemulsions as precursors to solid nanoparticles |
| US9700866B2 (en) | 2000-12-22 | 2017-07-11 | Baxter International Inc. | Surfactant systems for delivery of organic compounds |
| US7193084B2 (en) * | 2000-12-22 | 2007-03-20 | Baxter International Inc. | Polymorphic form of itraconazole |
| US8067032B2 (en) | 2000-12-22 | 2011-11-29 | Baxter International Inc. | Method for preparing submicron particles of antineoplastic agents |
| US6884436B2 (en) * | 2000-12-22 | 2005-04-26 | Baxter International Inc. | Method for preparing submicron particle suspensions |
| US7037528B2 (en) | 2000-12-22 | 2006-05-02 | Baxter International Inc. | Microprecipitation method for preparing submicron suspensions |
| US20050048126A1 (en) * | 2000-12-22 | 2005-03-03 | Barrett Rabinow | Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug |
| US20030096013A1 (en) * | 2000-12-22 | 2003-05-22 | Jane Werling | Preparation of submicron sized particles with polymorph control |
| US6977085B2 (en) | 2000-12-22 | 2005-12-20 | Baxter International Inc. | Method for preparing submicron suspensions with polymorph control |
| US20040256749A1 (en) * | 2000-12-22 | 2004-12-23 | Mahesh Chaubal | Process for production of essentially solvent-free small particles |
| US7033348B2 (en) * | 2001-04-10 | 2006-04-25 | The Research Foundation Of The City University Of New York | Gelatin based on Power-gel™ as solders for Cr4+laser tissue welding and sealing of lung air leak and fistulas in organs |
| US20060003012A9 (en) | 2001-09-26 | 2006-01-05 | Sean Brynjelsen | Preparation of submicron solid particle suspensions by sonication of multiphase systems |
| BR0212833A (pt) * | 2001-09-26 | 2004-10-13 | Baxter Int | Preparação de nanopartìculas de tamanho submìcron através de dispersão e de remoção de solvente ou de fase lìquida |
| US7112340B2 (en) * | 2001-10-19 | 2006-09-26 | Baxter International Inc. | Compositions of and method for preparing stable particles in a frozen aqueous matrix |
| AU2003223852A1 (en) | 2002-02-28 | 2003-09-09 | Wolf-Dieter Juelich | Micro/nanoparticle obtained from lipid-containing marine organisms for use in pharmaceutics and cosmetics |
| EP1534213B1 (en) * | 2002-03-13 | 2013-04-24 | Sköld, Thomas | Water-based delivery systems |
| ITMI20022323A1 (it) * | 2002-10-31 | 2004-05-01 | Maria Rosa Gasco | Composizioni farmaceutiche atte al trattamento di malattie oftalmiche. |
| EP1711163A2 (en) * | 2004-02-05 | 2006-10-18 | Baxter International Inc. | Dispersions prepared by use of self-stabilizing agents |
| US20060280787A1 (en) * | 2005-06-14 | 2006-12-14 | Baxter International Inc. | Pharmaceutical formulation of the tubulin inhibitor indibulin for oral administration with improved pharmacokinetic properties, and process for the manufacture thereof |
| JP2008543842A (ja) * | 2005-06-14 | 2008-12-04 | バクスター インターナショナル インコーポレイテッド | 薬物−薬物相互作用を最小にするための薬学的処方物 |
| BRPI0618661A2 (pt) * | 2005-11-15 | 2011-09-06 | Baxter Int | composições de inibidores de lipoxigenase |
| US20070154403A1 (en) * | 2006-01-05 | 2007-07-05 | Thomas Skold | Oral, Pulmonary and Transmucosal Delivery Composition |
| WO2008080047A2 (en) * | 2006-12-23 | 2008-07-03 | Baxter International Inc. | Magnetic separation of fine particles from compositions |
| US8722736B2 (en) * | 2007-05-22 | 2014-05-13 | Baxter International Inc. | Multi-dose concentrate esmolol with benzyl alcohol |
| US20080293814A1 (en) * | 2007-05-22 | 2008-11-27 | Deepak Tiwari | Concentrate esmolol |
| US8426467B2 (en) * | 2007-05-22 | 2013-04-23 | Baxter International Inc. | Colored esmolol concentrate |
| ITTO20070411A1 (it) * | 2007-06-08 | 2008-12-09 | Univ Degli Studi Torino | Metodo per la preparazione di micro e nanoparticelle lipidiche solide |
| US20090061009A1 (en) * | 2007-08-29 | 2009-03-05 | Joseph Schwarz | Composition and Method of Treatment of Bacterial Infections |
| DE102008035442A1 (de) | 2008-07-26 | 2010-01-28 | Ernst-Moritz-Arndt-Universität Greifswald | Zubereitungen aus Artemisia Annua, ihre Umwandlung in Mikro- und Nanopartikel und ihre Verwendung |
| WO2013105026A1 (en) * | 2012-01-09 | 2013-07-18 | Department Of Biotechnology (Dbt) | A process for preparing solid lipid sustained release nanoparticles for delivery of vitamins |
| DE102013224627A1 (de) * | 2013-11-29 | 2015-06-03 | Andreas Lauterbach | Pharmazeutische Formulierung mit Lipidmikropartikeln und Herstellungsverfahren |
| CA2950741C (en) * | 2014-05-30 | 2023-03-28 | Oms Investments, Inc. | Nano-sized water-based dispersion compositions and methods of making thereof |
| CA2974196C (en) | 2015-01-20 | 2023-12-12 | TetraDerm Group LLC | Versatile topical drug delivery vehicle and multifactorial tissue moisturizer that provides mucosal and skin barrier restoration |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5985354A (en) * | 1995-06-07 | 1999-11-16 | Brown University Research Foundation | Preparation of multiwall polymeric microcapsules from hydrophilic polymers |
| IT1240317B (it) * | 1990-02-22 | 1993-12-07 | Maria Rosa Gasco | Microsfere lipidiche solide a stretto intervallo dimensionale e relativo procedimento di preparazione |
| US5145684A (en) * | 1991-01-25 | 1992-09-08 | Sterling Drug Inc. | Surface modified drug nanoparticles |
| US5250236A (en) * | 1991-08-05 | 1993-10-05 | Gasco Maria R | Method for producing solid lipid microspheres having a narrow size distribution |
| CA2091152C (en) * | 1993-03-05 | 2005-05-03 | Kirsten Westesen | Solid lipid particles, particles of bioactive agents and methods for the manfuacture and use thereof |
| US5744155A (en) * | 1993-08-13 | 1998-04-28 | Friedman; Doron | Bioadhesive emulsion preparations for enhanced drug delivery |
-
1997
- 1997-06-12 IT IT97MI001385A patent/IT1292142B1/it active IP Right Grant
-
1998
- 1998-05-27 WO PCT/EP1998/003110 patent/WO1998056362A1/en active IP Right Grant
- 1998-05-27 AT AT98929383T patent/ATE235897T1/de active
- 1998-05-27 EP EP98929383A patent/EP0988031B1/en not_active Expired - Lifetime
- 1998-05-27 AU AU79158/98A patent/AU7915898A/en not_active Abandoned
- 1998-05-27 CA CA002294172A patent/CA2294172C/en not_active Expired - Fee Related
- 1998-05-27 US US09/445,603 patent/US6238694B1/en not_active Expired - Lifetime
- 1998-05-27 DE DE69812936T patent/DE69812936T2/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2294172C (en) | 2007-01-09 |
| ITMI971385A0 (enEXAMPLES) | 1997-06-12 |
| CA2294172A1 (en) | 1998-12-17 |
| DE69812936T2 (de) | 2004-01-29 |
| US6238694B1 (en) | 2001-05-29 |
| AU7915898A (en) | 1998-12-30 |
| EP0988031B1 (en) | 2003-04-02 |
| ITMI971385A1 (it) | 1998-12-12 |
| DE69812936D1 (de) | 2003-05-08 |
| WO1998056362A1 (en) | 1998-12-17 |
| IT1292142B1 (it) | 1999-01-25 |
| EP0988031A1 (en) | 2000-03-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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